relationships Gene Set

Dataset GeneRIF Biological Term Annotations
Category structural or functional annotations
Type biological term
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Genes

177 genes co-occuring with the biological term relationships in literature-supported statements describing functions of genes from the GeneRIF Biological Term Annotations dataset.

Symbol Name
A2M alpha-2-macroglobulin
ABCA4 ATP-binding cassette, sub-family A (ABC1), member 4
ABCB1 ATP-binding cassette, sub-family B (MDR/TAP), member 1
ABCC2 ATP-binding cassette, sub-family C (CFTR/MRP), member 2
ABCG1 ATP-binding cassette, sub-family G (WHITE), member 1
ACE angiotensin I converting enzyme
ACTA2 actin, alpha 2, smooth muscle, aorta
ACTN3 actinin, alpha 3 (gene/pseudogene)
ACVR2B activin A receptor, type IIB
ADAR adenosine deaminase, RNA-specific
ADD2 adducin 2 (beta)
ADIPOQ adiponectin, C1Q and collagen domain containing
AFP alpha-fetoprotein
AGER advanced glycosylation end product-specific receptor
AHCYL1 adenosylhomocysteinase-like 1
ALPL alkaline phosphatase, liver/bone/kidney
APOE apolipoprotein E
APOO apolipoprotein O
APP amyloid beta (A4) precursor protein
ARMS2 age-related maculopathy susceptibility 2
BCL2 B-cell CLL/lymphoma 2
BGLAP bone gamma-carboxyglutamate (gla) protein
BMP7 bone morphogenetic protein 7
C5 complement component 5
CA9 carbonic anhydrase IX
CALCA calcitonin-related polypeptide alpha
CALY calcyon neuron-specific vesicular protein
CAV1 caveolin 1, caveolae protein, 22kDa
CCR7 chemokine (C-C motif) receptor 7
CD22 CD22 molecule
CD27 CD27 molecule
CD38 CD38 molecule
CD59 CD59 molecule, complement regulatory protein
CD63 CD63 molecule
CD79B CD79b molecule, immunoglobulin-associated beta
CDC7 cell division cycle 7
CDH1 cadherin 1, type 1, E-cadherin (epithelial)
CDKN1C cyclin-dependent kinase inhibitor 1C (p57, Kip2)
CDKN2A cyclin-dependent kinase inhibitor 2A
CFTR cystic fibrosis transmembrane conductance regulator (ATP-binding cassette sub-family C, member 7)
CHI3L1 chitinase 3-like 1 (cartilage glycoprotein-39)
CLCN1 chloride channel, voltage-sensitive 1
COMT catechol-O-methyltransferase
CORIN corin, serine peptidase
CRP C-reactive protein, pentraxin-related
CST3 cystatin C
CTNNB1 catenin (cadherin-associated protein), beta 1, 88kDa
CX3CL1 chemokine (C-X3-C motif) ligand 1
CXCL12 chemokine (C-X-C motif) ligand 12
CXCL8 chemokine (C-X-C motif) ligand 8
CYP17A1 cytochrome P450, family 17, subfamily A, polypeptide 1
CYP19A1 cytochrome P450, family 19, subfamily A, polypeptide 1
CYP2A6 cytochrome P450, family 2, subfamily A, polypeptide 6
DIO1 deiodinase, iodothyronine, type I
DRD2 dopamine receptor D2
DUSP2 dual specificity phosphatase 2
EDN1 endothelin 1
EEF1A1 eukaryotic translation elongation factor 1 alpha 1
EGFR epidermal growth factor receptor
EPHX2 epoxide hydrolase 2, cytoplasmic
ERBB2 erb-b2 receptor tyrosine kinase 2
ERCC2 excision repair cross-complementation group 2
F3 coagulation factor III (thromboplastin, tissue factor)
FCER1A Fc fragment of IgE, high affinity I, receptor for; alpha polypeptide
FCER2 Fc fragment of IgE, low affinity II, receptor for (CD23)
FCN2 ficolin (collagen/fibrinogen domain containing lectin) 2
FGF2 fibroblast growth factor 2 (basic)
FGF23 fibroblast growth factor 23
FST follistatin
FTO fat mass and obesity associated
GABBR1 gamma-aminobutyric acid (GABA) B receptor, 1
GBA glucosidase, beta, acid
GGT2 gamma-glutamyltransferase 2
GHRL ghrelin/obestatin prepropeptide
GNLY granulysin
GNRHR gonadotropin-releasing hormone receptor
GRM3 glutamate receptor, metabotropic 3
GSTM1 glutathione S-transferase mu 1
GSTT1 glutathione S-transferase theta 1
H19 H19, imprinted maternally expressed transcript (non-protein coding)
HFE hemochromatosis
HIF1A hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor)
HLA-DQB1 major histocompatibility complex, class II, DQ beta 1
HLA-DRB1 major histocompatibility complex, class II, DR beta 1
HMOX1 heme oxygenase 1
HNF1B HNF1 homeobox B
HORMAD1 HORMA domain containing 1
HP haptoglobin
HSD3B1 hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 1
HSD3B2 hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 2
HTR2A 5-hydroxytryptamine (serotonin) receptor 2A, G protein-coupled
HTR2B 5-hydroxytryptamine (serotonin) receptor 2B, G protein-coupled
ICAM1 intercellular adhesion molecule 1
IDO2 indoleamine 2,3-dioxygenase 2
IFNG interferon, gamma
IFNGR1 interferon gamma receptor 1
IFNL3 interferon, lambda 3
IGF1 insulin-like growth factor 1 (somatomedin C)
IGFBP1 insulin-like growth factor binding protein 1
IL17A interleukin 17A
IL1A interleukin 1, alpha
IL1B interleukin 1, beta
IL6 interleukin 6
IRF7 interferon regulatory factor 7
IRS2 insulin receptor substrate 2
ITGA2B integrin, alpha 2b (platelet glycoprotein IIb of IIb/IIIa complex, antigen CD41)
ITGB3 integrin, beta 3 (platelet glycoprotein IIIa, antigen CD61)
KCNH2 potassium channel, voltage gated eag related subfamily H, member 2
KISS1 KiSS-1 metastasis-suppressor
LCT lactase
LEP leptin
LEPR leptin receptor
LHCGR luteinizing hormone/choriogonadotropin receptor
LMNA lamin A/C
MAOA monoamine oxidase A
MAPT microtubule-associated protein tau
MECP2 methyl CpG binding protein 2
MGEA5 meningioma expressed antigen 5 (hyaluronidase)
MKI67 marker of proliferation Ki-67
MMP7 matrix metallopeptidase 7
MSH2 mutS homolog 2
NAT1 N-acetyltransferase 1 (arylamine N-acetyltransferase)
NAT2 N-acetyltransferase 2 (arylamine N-acetyltransferase)
NOTCH3 notch 3
NPPB natriuretic peptide B
NPY neuropeptide Y
NPY2R neuropeptide Y receptor Y2
NR1H4 nuclear receptor subfamily 1, group H, member 4
P2RX7 purinergic receptor P2X, ligand gated ion channel, 7
PCNA proliferating cell nuclear antigen
PLET1 placenta expressed transcript 1
POLG polymerase (DNA directed), gamma
PON1 paraoxonase 1
PON3 paraoxonase 3
PPARD peroxisome proliferator-activated receptor delta
PPARGC1A peroxisome proliferator-activated receptor gamma, coactivator 1 alpha
PSMB10 proteasome (prosome, macropain) subunit, beta type, 10
PSMD3 proteasome (prosome, macropain) 26S subunit, non-ATPase, 3
PTCH1 patched 1
PTGS1 prostaglandin-endoperoxide synthase 1 (prostaglandin G/H synthase and cyclooxygenase)
PTGS2 prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase)
PXN paxillin
RAB27A RAB27A, member RAS oncogene family
RAP1B RAP1B, member of RAS oncogene family
RB1 retinoblastoma 1
SCML2 sex comb on midleg-like 2 (Drosophila)
SCNN1A sodium channel, non voltage gated 1 alpha subunit
SELM selenoprotein M
SERPINE1 serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1
SHBG sex hormone-binding globulin
SHC1 SHC (Src homology 2 domain containing) transforming protein 1
SIRPA signal-regulatory protein alpha
SLC11A1 solute carrier family 11 (proton-coupled divalent metal ion transporter), member 1
SLC11A2 solute carrier family 11 (proton-coupled divalent metal ion transporter), member 2
SLC18A2 solute carrier family 18 (vesicular monoamine transporter), member 2
SLC2A1 solute carrier family 2 (facilitated glucose transporter), member 1
SLC6A4 solute carrier family 6 (neurotransmitter transporter), member 4
SOD1 superoxide dismutase 1, soluble
SOD2 superoxide dismutase 2, mitochondrial
SOST sclerostin
SULT1A3 sulfotransferase family, cytosolic, 1A, phenol-preferring, member 3
TAC3 tachykinin 3
TACC1 transforming, acidic coiled-coil containing protein 1
TACR3 tachykinin receptor 3
TERT telomerase reverse transcriptase
TGM2 transglutaminase 2
THPO thrombopoietin
TLR2 toll-like receptor 2
TNFAIP3 tumor necrosis factor, alpha-induced protein 3
TNFRSF11B tumor necrosis factor receptor superfamily, member 11b
TOR1A torsin family 1, member A (torsin A)
TP53 tumor protein p53
TSHR thyroid stimulating hormone receptor
TWIST1 twist family bHLH transcription factor 1
UCHL1 ubiquitin carboxyl-terminal esterase L1 (ubiquitin thiolesterase)
UGT1A1 UDP glucuronosyltransferase 1 family, polypeptide A1
VEGFA vascular endothelial growth factor A