relaxation of muscle Gene Set
Dataset
GO Biological Process Annotations 2015
Category
structural or functional annotations
Type
biological process
Description
A process in which the extent of muscle contraction is reduced. Muscle relaxation can involve a number of processes including the removal of calcium from the cytoplasm to the sarcoplasmic reticulum lumen through the action of Ca2+ ATPases. In some muscles, calcium-independent pathways also play a role in muscle relaxation by decreasing the phosphorylation state of myosin light chain. (Gene Ontology , GO_0090075 )
External Link
http://amigo.geneontology.org/amigo/term/GO:0090075
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Genes
19 genes participating in the relaxation of muscle biological process from the curated GO Biological Process Annotations 2015 dataset.
Symbol
Name
ADORA1
adenosine A1 receptor
ADORA2B
adenosine A2b receptor
ATP1A1
ATPase, Na+/K+ transporting, alpha 1 polypeptide
ATP1A2
ATPase, Na+/K+ transporting, alpha 2 polypeptide
ATP1B1
ATPase, Na+/K+ transporting, beta 1 polypeptide
ATP2A1
ATPase, Ca++ transporting, cardiac muscle, fast twitch 1
CAMK2D
calcium/calmodulin-dependent protein kinase II delta
GSTM2
glutathione S-transferase mu 2 (muscle)
GUCY1A3
guanylate cyclase 1, soluble, alpha 3
KCNJ2
potassium channel, inwardly rectifying subfamily J, member 2
MRVI1
murine retrovirus integration site 1 homolog
P2RX4
purinergic receptor P2X, ligand gated ion channel, 4
P2RY1
purinergic receptor P2Y, G-protein coupled, 1
PDE5A
phosphodiesterase 5A, cGMP-specific
PLN
phospholamban
PRKG1
protein kinase, cGMP-dependent, type I
RGS2
regulator of G-protein signaling 2
SLC8A1
solute carrier family 8 (sodium/calcium exchanger), member 1
SOD1
superoxide dismutase 1, soluble