relaxation of muscle Gene Set
Dataset
GO Biological Process Annotations 2025
Category
structural or functional annotations
Type
biological process
Description
A process in which the extent of muscle contraction is reduced. Muscle relaxation can involve a number of processes including the removal of calcium from the cytoplasm to the sarcoplasmic reticulum lumen through the action of Ca2+ ATPases. In some muscles, calcium-independent pathways also play a role in muscle relaxation by decreasing the phosphorylation state of myosin light chain. (Gene Ontology , GO_0090075 )
External Link
http://amigo.geneontology.org/amigo/term/GO:0090075
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Genes
15 genes participating in the relaxation of muscle biological process from the curated GO Biological Process Annotations 2025 dataset.
Symbol
Name
ATP1A2
ATPase, Na+/K+ transporting, alpha 2 polypeptide
ATP1A4
ATPase, Na+/K+ transporting, alpha 4 polypeptide
ATP1B1
ATPase, Na+/K+ transporting, beta 1 polypeptide
ATP2A1
ATPase, Ca++ transporting, cardiac muscle, fast twitch 1
ATP2A2
ATPase, Ca++ transporting, cardiac muscle, slow twitch 2
CAMK2D
calcium/calmodulin-dependent protein kinase II delta
GSN
gelsolin
GSTM2
glutathione S-transferase mu 2 (muscle)
KBTBD13
kelch repeat and BTB (POZ) domain containing 13
KCNJ2
potassium channel, inwardly rectifying subfamily J, member 2
P2RX4
purinergic receptor P2X, ligand gated ion channel, 4
PIK3CA
phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit alpha
PLN
phospholamban
RGS2
regulator of G-protein signaling 2
SLC8A1
solute carrier family 8 (sodium/calcium exchanger), member 1