relaxation of vascular smooth muscle Gene Set

Dataset GO Biological Process Annotations
Category structural or functional annotations
Type biological process
Description A process in which the extent of vascular smooth muscle contraction is reduced. Vascular smooth muscle relaxation is mediated via a decrease in the phosphorylation state of myosin light chain. This can be achieved by removal of calcium from the cytoplasm to the sarcoplasmic reticulum lumen through the action of Ca2+ ATPases leading to a decrease myosin light chain kinase activity, and through calcium-independent pathways leading to a increase in myosin light chain phosphatase activity. (Gene Ontology, GO_0060087)
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7 genes participating in the relaxation of vascular smooth muscle biological process from the curated GO Biological Process Annotations dataset.

Symbol Name
ADORA1 adenosine A1 receptor
ADORA2B adenosine A2b receptor
GUCY1A3 guanylate cyclase 1, soluble, alpha 3
MRVI1 murine retrovirus integration site 1 homolog
PRKG1 protein kinase, cGMP-dependent, type I
RGS2 regulator of G-protein signaling 2
SOD1 superoxide dismutase 1, soluble