remoxipride-5443 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

199 genes differentially expressed following the remoxipride-5443 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ABCA7 ATP-binding cassette, sub-family A (ABC1), member 7
ACADS acyl-CoA dehydrogenase, C-2 to C-3 short chain
ACPP acid phosphatase, prostate
AGFG2 ArfGAP with FG repeats 2
ATN1 atrophin 1
ATP10A ATPase, class V, type 10A
BIN1 bridging integrator 1
BST1 bone marrow stromal cell antigen 1
C3 complement component 3
CACNA1D calcium channel, voltage-dependent, L type, alpha 1D subunit
CCRL2 chemokine (C-C motif) receptor-like 2
CD3D CD3d molecule, delta (CD3-TCR complex)
CD48 CD48 molecule
CD58 CD58 molecule
CDRT1 CMT1A duplicated region transcript 1
CLEC4E C-type lectin domain family 4, member E
COL5A1 collagen, type V, alpha 1
CSTA cystatin A (stefin A)
CYP4F11 cytochrome P450, family 4, subfamily F, polypeptide 11
DCAF4 DDB1 and CUL4 associated factor 4
DMBT1 deleted in malignant brain tumors 1
EFNB3 ephrin-B3
ELSPBP1 epididymal sperm binding protein 1
ENOX1 ecto-NOX disulfide-thiol exchanger 1
ERO1LB ERO1-like beta (S. cerevisiae)
EXT1 exostosin glycosyltransferase 1
FAM214B family with sequence similarity 214, member B
FLOT1 flotillin 1
FUT3 fucosyltransferase 3 (galactoside 3(4)-L-fucosyltransferase, Lewis blood group)
FZR1 fizzy/cell division cycle 20 related 1 (Drosophila)
GATM glycine amidinotransferase (L-arginine:glycine amidinotransferase)
GLS glutaminase
HCN4 hyperpolarization activated cyclic nucleotide gated potassium channel 4
HOXB2 homeobox B2
HPCAL4 hippocalcin like 4
HPGD hydroxyprostaglandin dehydrogenase 15-(NAD)
HS3ST2 heparan sulfate (glucosamine) 3-O-sulfotransferase 2
IFI27 interferon, alpha-inducible protein 27
IFI6 interferon, alpha-inducible protein 6
IFIT1 interferon-induced protein with tetratricopeptide repeats 1
IFITM1 interferon induced transmembrane protein 1
IPW imprinted in Prader-Willi syndrome (non-protein coding)
ISG15 ISG15 ubiquitin-like modifier
ITIH5 inter-alpha-trypsin inhibitor heavy chain family, member 5
ITM2C integral membrane protein 2C
ITPR1 inositol 1,4,5-trisphosphate receptor, type 1
KCNAB1 potassium channel, voltage gated subfamily A regulatory beta subunit 1
KDM8 lysine (K)-specific demethylase 8
KIF21B kinesin family member 21B
KLK13 kallikrein-related peptidase 13
KLK7 kallikrein-related peptidase 7
LMF2 lipase maturation factor 2
MALL mal, T-cell differentiation protein-like
MAP4 microtubule-associated protein 4
MC2R melanocortin 2 receptor (adrenocorticotropic hormone)
MCPH1 microcephalin 1
MIER2 mesoderm induction early response 1, family member 2
MMP25 matrix metallopeptidase 25
MOBP myelin-associated oligodendrocyte basic protein
N4BP2L2-IT2 N4BPL2 intronic transcript 2
NF1 neurofibromin 1
NIPSNAP3B nipsnap homolog 3B (C. elegans)
NKG7 natural killer cell granule protein 7
NOP16 NOP16 nucleolar protein
NR2E3 nuclear receptor subfamily 2, group E, member 3
NTF3 neurotrophin 3
PAX8 paired box 8
PCDH9 protocadherin 9
PIDD1 p53-induced death domain protein 1
PLCB3 phospholipase C, beta 3 (phosphatidylinositol-specific)
PLEKHO2 pleckstrin homology domain containing, family O member 2
PRKDC protein kinase, DNA-activated, catalytic polypeptide
PTPRO protein tyrosine phosphatase, receptor type, O
RHO rhodopsin
RPL35A ribosomal protein L35a
S100A7 S100 calcium binding protein A7
S100A8 S100 calcium binding protein A8
SC5D sterol-C5-desaturase
SCARF1 scavenger receptor class F, member 1
SCN11A sodium channel, voltage gated, type XI alpha subunit
SECTM1 secreted and transmembrane 1
SH3BP2 SH3-domain binding protein 2
SLC16A5 solute carrier family 16 (monocarboxylate transporter), member 5
SLC24A2 solute carrier family 24 (sodium/potassium/calcium exchanger), member 2
SULT4A1 sulfotransferase family 4A, member 1
TGFBR1 transforming growth factor, beta receptor 1
TGM2 transglutaminase 2
TMEM212 transmembrane protein 212
TNFRSF25 tumor necrosis factor receptor superfamily, member 25
TNIK TRAF2 and NCK interacting kinase
UCHL1 ubiquitin carboxyl-terminal esterase L1 (ubiquitin thiolesterase)
USP22 ubiquitin specific peptidase 22
VN1R1 vomeronasal 1 receptor 1
XRCC6 X-ray repair complementing defective repair in Chinese hamster cells 6
ZIC3 Zic family member 3
ZNF3 zinc finger protein 3
ZNF423 zinc finger protein 423
ZNF516 zinc finger protein 516
ZNF76 zinc finger protein 76

decreased expression

Symbol Name
ABHD17B abhydrolase domain containing 17B
ACTG2 actin, gamma 2, smooth muscle, enteric
ADCY7 adenylate cyclase 7
ADGRG2 adhesion G protein-coupled receptor G2
ADPRM ADP-ribose/CDP-alcohol diphosphatase, manganese-dependent
AKR1B1 aldo-keto reductase family 1, member B1 (aldose reductase)
ANKFY1 ankyrin repeat and FYVE domain containing 1
ANXA1 annexin A1
ANXA2P3 annexin A2 pseudogene 3
AOC2 amine oxidase, copper containing 2 (retina-specific)
ARSB arylsulfatase B
B3GALT4 UDP-Gal:betaGlcNAc beta 1,3-galactosyltransferase, polypeptide 4
C10ORF95 chromosome 10 open reading frame 95
C19ORF73 chromosome 19 open reading frame 73
C1QTNF3 C1q and tumor necrosis factor related protein 3
C2ORF54 chromosome 2 open reading frame 54
CARF calcium responsive transcription factor
CCDC186 coiled-coil domain containing 186
CCDC71 coiled-coil domain containing 71
CDKN2D cyclin-dependent kinase inhibitor 2D (p19, inhibits CDK4)
CLCN6 chloride channel, voltage-sensitive 6
CNGB3 cyclic nucleotide gated channel beta 3
COPZ2 coatomer protein complex, subunit zeta 2
CRLF1 cytokine receptor-like factor 1
CRYBB2P1 crystallin, beta B2 pseudogene 1
DEAF1 DEAF1 transcription factor
DGKE diacylglycerol kinase, epsilon 64kDa
DPY19L1P1 DPY19L1 pseudogene 1
DSCAM Down syndrome cell adhesion molecule
DUSP2 dual specificity phosphatase 2
ERCC6 excision repair cross-complementation group 6
FBXO31 F-box protein 31
FBXO4 F-box protein 4
FGD1 FYVE, RhoGEF and PH domain containing 1
GADD45G growth arrest and DNA-damage-inducible, gamma
GAN gigaxonin
GFPT2 glutamine-fructose-6-phosphate transaminase 2
GLB1L galactosidase, beta 1-like
GPR143 G protein-coupled receptor 143
HIST1H1B histone cluster 1, H1b
HIST1H3B histone cluster 1, H3b
HIST1H4C histone cluster 1, H4c
HP1BP3 heterochromatin protein 1, binding protein 3
INPP5J inositol polyphosphate-5-phosphatase J
KCNMB3 potassium channel subfamily M regulatory beta subunit 3
KIFC1 kinesin family member C1
KLRG1 killer cell lectin-like receptor subfamily G, member 1
LAMC3 laminin, gamma 3
LEFTY1 left-right determination factor 1
LHX6 LIM homeobox 6
LIN7A lin-7 homolog A (C. elegans)
LOC730101 uncharacterized LOC730101
LRRC6 leucine rich repeat containing 6
LSM14B LSM14B, SCD6 homolog B (S. cerevisiae)
MAPKBP1 mitogen-activated protein kinase binding protein 1
MAST3 microtubule associated serine/threonine kinase 3
MUC3A mucin 3A, cell surface associated
NOL12 nucleolar protein 12
NPFFR1 neuropeptide FF receptor 1
OR7E47P olfactory receptor, family 7, subfamily E, member 47 pseudogene
OSGIN1 oxidative stress induced growth inhibitor 1
PCDHB13 protocadherin beta 13
PCDHB8 protocadherin beta 8
PDE12 phosphodiesterase 12
PDE8B phosphodiesterase 8B
PELI1 pellino E3 ubiquitin protein ligase 1
POMT2 protein-O-mannosyltransferase 2
PRICKLE3 prickle homolog 3 (Drosophila)
PSG4 pregnancy specific beta-1-glycoprotein 4
PTDSS2 phosphatidylserine synthase 2
PTPN14 protein tyrosine phosphatase, non-receptor type 14
PVRL3 poliovirus receptor-related 3
QPCTL glutaminyl-peptide cyclotransferase-like
RAB30 RAB30, member RAS oncogene family
RHOBTB2 Rho-related BTB domain containing 2
RNF122 ring finger protein 122
RNF39 ring finger protein 39
S100A4 S100 calcium binding protein A4
SCGB2A2 secretoglobin, family 2A, member 2
SCML2 sex comb on midleg-like 2 (Drosophila)
SERPINI1 serpin peptidase inhibitor, clade I (neuroserpin), member 1
SHARPIN SHANK-associated RH domain interactor
SLC17A5 solute carrier family 17 (acidic sugar transporter), member 5
SLC22A18AS solute carrier family 22 (organic cation transporter), member 18 antisense
SNHG3 small nucleolar RNA host gene 3
SOAT2 sterol O-acyltransferase 2
SP1 Sp1 transcription factor
SRD5A3 steroid 5 alpha-reductase 3
STRA6 stimulated by retinoic acid 6
TAOK1 TAO kinase 1
TBL1XR1 transducin (beta)-like 1 X-linked receptor 1
TNFSF9 tumor necrosis factor (ligand) superfamily, member 9
TRAIP TRAF interacting protein
TSGA10 testis specific, 10
VASH2 vasohibin 2
VCPIP1 valosin containing protein (p97)/p47 complex interacting protein 1
ZFP69B ZFP69 zinc finger protein B
ZNF250 zinc finger protein 250
ZNF365 zinc finger protein 365
ZNF701 zinc finger protein 701