renal cast Gene Set

Dataset MPO Gene-Phenotype Associations
Category disease or phenotype associations
Type phenotype
Description any of the various casts formed from gelled protein precipitated in the distal convoluted tubules and collecting ducts of nephrons and molded to the tubular or duct lumen which dislodge and pass into the urine; types named for their constituent material include acellular casts (e.g. granular, hyaline, waxy, or fatty casts) and cellular casts (e.g. red or white blood cell casts) (Mammalian Phenotype Ontology, MP_0011402)
External Link http://www.informatics.jax.org/searches/Phat.cgi?id=MP:0011402
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Genes

28 gene mutations causing the renal cast phenotype in transgenic mice from the MPO Gene-Phenotype Associations dataset.

Symbol Name
ACTN4 actinin, alpha 4
APRT adenine phosphoribosyltransferase
ARHGDIA Rho GDP dissociation inhibitor (GDI) alpha
ASIP agouti signaling protein
BCL2L11 BCL2-like 11 (apoptosis facilitator)
C1GALT1 core 1 synthase, glycoprotein-N-acetylgalactosamine 3-beta-galactosyltransferase 1
CD151 CD151 molecule (Raph blood group)
COL4A3 collagen, type IV, alpha 3 (Goodpasture antigen)
FAS Fas cell surface death receptor
FASLG Fas ligand (TNF superfamily, member 6)
GLIS2 GLIS family zinc finger 2
GOLM1 golgi membrane protein 1
GRM1 glutamate receptor, metabotropic 1
HMOX1 heme oxygenase 1
MYO1E myosin IE
NOS3 nitric oxide synthase 3 (endothelial cell)
NPHS2 nephrosis 2, idiopathic, steroid-resistant (podocin)
PCCA propionyl CoA carboxylase, alpha polypeptide
PDSS2 prenyl (decaprenyl) diphosphate synthase, subunit 2
PRDX6 peroxiredoxin 6
PTGS2 prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase)
RET ret proto-oncogene
SLC7A9 solute carrier family 7 (amino acid transporter light chain, bo,+ system), member 9
TLR4 toll-like receptor 4
TNS1 tensin 1
TUSC2 tumor suppressor candidate 2
UOX urate oxidase, pseudogene
WT1 Wilms tumor 1