renal necrosis Gene Set

Dataset MPO Gene-Phenotype Associations
Category disease or phenotype associations
Type phenotype
Description morphological changes resulting from pathological death of renal tissue; usually due to irreversible damage (Mammalian Phenotype Ontology, MP_0003946)
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22 gene mutations causing the renal necrosis phenotype in transgenic mice from the MPO Gene-Phenotype Associations dataset.

Symbol Name
APRT adenine phosphoribosyltransferase
BCR breakpoint cluster region
CRIM1 cysteine rich transmembrane BMP regulator 1 (chordin-like)
DNASE1 deoxyribonuclease I
GSTZ1 glutathione S-transferase zeta 1
HELLS helicase, lymphoid-specific
HMOX1 heme oxygenase 1
ITGB3 integrin, beta 3 (platelet glycoprotein IIIa, antigen CD61)
NOS3 nitric oxide synthase 3 (endothelial cell)
PKHD1 polycystic kidney and hepatic disease 1 (autosomal recessive)
PTGIS prostaglandin I2 (prostacyclin) synthase
RRM2B ribonucleotide reductase M2 B (TP53 inducible)
SALL1 spalt-like transcription factor 1
SLC7A9 solute carrier family 7 (amino acid transporter light chain, bo,+ system), member 9
SMAD3 SMAD family member 3
SPP1 secreted phosphoprotein 1
SPTA1 spectrin, alpha, erythrocytic 1
SPTB spectrin, beta, erythrocytic
TGFB1 transforming growth factor, beta 1
TLR4 toll-like receptor 4
TREX1 three prime repair exonuclease 1
UMOD uromodulin