repaglinide-5862 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

197 genes differentially expressed following the repaglinide-5862 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ABCG1 ATP-binding cassette, sub-family G (WHITE), member 1
ACSS3 acyl-CoA synthetase short-chain family member 3
AGO4 argonaute RISC catalytic component 4
AMACR alpha-methylacyl-CoA racemase
ANGPTL2 angiopoietin-like 2
ANKFY1 ankyrin repeat and FYVE domain containing 1
AP1S1 adaptor-related protein complex 1, sigma 1 subunit
APC adenomatous polyposis coli
ARHGAP26 Rho GTPase activating protein 26
ARVCF armadillo repeat gene deleted in velocardiofacial syndrome
ATP2A2 ATPase, Ca++ transporting, cardiac muscle, slow twitch 2
BAHCC1 BAH domain and coiled-coil containing 1
BCAN brevican
C1ORF54 chromosome 1 open reading frame 54
CA9 carbonic anhydrase IX
CACTIN cactin, spliceosome C complex subunit
CASS4 Cas scaffolding protein family member 4
CCKAR cholecystokinin A receptor
CD2 CD2 molecule
CDH4 cadherin 4, type 1, R-cadherin (retinal)
CEP41 centrosomal protein 41kDa
CNOT4 CCR4-NOT transcription complex, subunit 4
COPE coatomer protein complex, subunit epsilon
CPNE7 copine VII
CYP2C9 cytochrome P450, family 2, subfamily C, polypeptide 9
DCN decorin
DNAJA4 DnaJ (Hsp40) homolog, subfamily A, member 4
DNASE1L2 deoxyribonuclease I-like 2
DUSP7 dual specificity phosphatase 7
ELSPBP1 epididymal sperm binding protein 1
FAM134B family with sequence similarity 134, member B
FAM65B family with sequence similarity 65, member B
FLT3LG fms-related tyrosine kinase 3 ligand
FNTB farnesyltransferase, CAAX box, beta
FSTL3 follistatin-like 3 (secreted glycoprotein)
FUT7 fucosyltransferase 7 (alpha (1,3) fucosyltransferase)
FZD10 frizzled class receptor 10
GGA2 golgi-associated, gamma adaptin ear containing, ARF binding protein 2
GREB1L growth regulation by estrogen in breast cancer-like
HDAC5 histone deacetylase 5
HNF4A hepatocyte nuclear factor 4, alpha
HPS4 Hermansky-Pudlak syndrome 4
HSD17B14 hydroxysteroid (17-beta) dehydrogenase 14
ITGA7 integrin, alpha 7
ITIH3 inter-alpha-trypsin inhibitor heavy chain 3
KCTD14 potassium channel tetramerization domain containing 14
KLHL29 kelch-like family member 29
LMF2 lipase maturation factor 2
LMTK2 lemur tyrosine kinase 2
MTHFR methylenetetrahydrofolate reductase (NAD(P)H)
MZF1 myeloid zinc finger 1
NLGN1 neuroligin 1
NPY6R neuropeptide Y receptor Y6 (pseudogene)
ODAM odontogenic, ameloblast asssociated
PASK PAS domain containing serine/threonine kinase
PCDHGB6 protocadherin gamma subfamily B, 6
PIK3R5 phosphoinositide-3-kinase, regulatory subunit 5
PKNOX2 PBX/knotted 1 homeobox 2
PRKACG protein kinase, cAMP-dependent, catalytic, gamma
PTCRA pre T-cell antigen receptor alpha
PTGDS prostaglandin D2 synthase 21kDa (brain)
PTPRD protein tyrosine phosphatase, receptor type, D
PTPRR protein tyrosine phosphatase, receptor type, R
RAB26 RAB26, member RAS oncogene family
RAB6B RAB6B, member RAS oncogene family
RAD50 RAD50 homolog (S. cerevisiae)
RAD51B RAD51 paralog B
RAD51D RAD51 paralog D
RAPGEFL1 Rap guanine nucleotide exchange factor (GEF)-like 1
RGS12 regulator of G-protein signaling 12
ROCK2 Rho-associated, coiled-coil containing protein kinase 2
RPL35A ribosomal protein L35a
RUNX1T1 runt-related transcription factor 1; translocated to, 1 (cyclin D-related)
SATB2 SATB homeobox 2
SCD stearoyl-CoA desaturase (delta-9-desaturase)
SENP3 SUMO1/sentrin/SMT3 specific peptidase 3
SFTPD surfactant protein D
SIRT3 sirtuin 3
SIRT5 sirtuin 5
SLC18A1 solute carrier family 18 (vesicular monoamine transporter), member 1
SPOCK2 sparc/osteonectin, cwcv and kazal-like domains proteoglycan (testican) 2
SPTB spectrin, beta, erythrocytic
ST3GAL5 ST3 beta-galactoside alpha-2,3-sialyltransferase 5
STAG3 stromal antigen 3
STS steroid sulfatase (microsomal), isozyme S
SYK spleen tyrosine kinase
THAP9 THAP domain containing 9
THPO thrombopoietin
TJAP1 tight junction associated protein 1 (peripheral)
TK2 thymidine kinase 2, mitochondrial
TRIM25 tripartite motif containing 25
UBA6 ubiquitin-like modifier activating enzyme 6
UBXN1 UBX domain protein 1
WDR78 WD repeat domain 78
ZCCHC11 zinc finger, CCHC domain containing 11
ZFP30 ZFP30 zinc finger protein
ZNF280A zinc finger protein 280A
ZNF589 zinc finger protein 589

decreased expression

Symbol Name
A1CF APOBEC1 complementation factor
AATF apoptosis antagonizing transcription factor
ACKR3 atypical chemokine receptor 3
ACYP1 acylphosphatase 1, erythrocyte (common) type
ADGRG2 adhesion G protein-coupled receptor G2
ANKRD36 ankyrin repeat domain 36
APOL6 apolipoprotein L, 6
APPL1 adaptor protein, phosphotyrosine interaction, PH domain and leucine zipper containing 1
ARL14 ADP-ribosylation factor-like 14
ATP10D ATPase, class V, type 10D
BCL2L2 BCL2-like 2
C5 complement component 5
C5ORF30 chromosome 5 open reading frame 30
C7ORF43 chromosome 7 open reading frame 43
CCDC68 coiled-coil domain containing 68
CHKB choline kinase beta
CHMP6 charged multivesicular body protein 6
CHPF chondroitin polymerizing factor
CLSPN claspin
CORT cortistatin
CTSO cathepsin O
CWC25 CWC25 spliceosome-associated protein homolog (S. cerevisiae)
CYP27A1 cytochrome P450, family 27, subfamily A, polypeptide 1
DHRS11 dehydrogenase/reductase (SDR family) member 11
DNAJC3 DnaJ (Hsp40) homolog, subfamily C, member 3
DYNC1I1 dynein, cytoplasmic 1, intermediate chain 1
EFNA3 ephrin-A3
ELOVL4 ELOVL fatty acid elongase 4
ERMAP erythroblast membrane-associated protein (Scianna blood group)
ERN2 endoplasmic reticulum to nucleus signaling 2
FADS2 fatty acid desaturase 2
FGF13 fibroblast growth factor 13
GATC glutamyl-tRNA(Gln) amidotransferase, subunit C
GCA grancalcin, EF-hand calcium binding protein
GLCE glucuronic acid epimerase
GNAZ guanine nucleotide binding protein (G protein), alpha z polypeptide
GPHN gephyrin
GPR137B G protein-coupled receptor 137B
GSTZ1 glutathione S-transferase zeta 1
GTF2H2B general transcription factor IIH, polypeptide 2B (pseudogene)
HAUS6 HAUS augmin-like complex, subunit 6
IMPDH1 IMP (inosine 5'-monophosphate) dehydrogenase 1
INPP5E inositol polyphosphate-5-phosphatase, 72 kDa
IQCE IQ motif containing E
IRF1 interferon regulatory factor 1
KCTD15 potassium channel tetramerization domain containing 15
KIAA0895 KIAA0895
KLHL12 kelch-like family member 12
LRP5L low density lipoprotein receptor-related protein 5-like
MANEA mannosidase, endo-alpha
MCM3 minichromosome maintenance complex component 3
MRPL2 mitochondrial ribosomal protein L2
MTRF1 mitochondrial translational release factor 1
MYLK myosin light chain kinase
NME6 NME/NM23 nucleoside diphosphate kinase 6
NPM3 nucleophosmin/nucleoplasmin 3
OAS3 2'-5'-oligoadenylate synthetase 3, 100kDa
ODF2 outer dense fiber of sperm tails 2
PARP16 poly (ADP-ribose) polymerase family, member 16
PECR peroxisomal trans-2-enoyl-CoA reductase
PLEKHO2 pleckstrin homology domain containing, family O member 2
PMCH pro-melanin-concentrating hormone
PRKRIP1 PRKR interacting protein 1 (IL11 inducible)
PRMT7 protein arginine methyltransferase 7
PRSS16 protease, serine, 16 (thymus)
QTRT1 queuine tRNA-ribosyltransferase 1
RAB3A RAB3A, member RAS oncogene family
RCBTB2 regulator of chromosome condensation (RCC1) and BTB (POZ) domain containing protein 2
RMND1 required for meiotic nuclear division 1 homolog (S. cerevisiae)
RNF121 ring finger protein 121
RRNAD1 ribosomal RNA adenine dimethylase domain containing 1
SCAMP5 secretory carrier membrane protein 5
SCN1B sodium channel, voltage gated, type I beta subunit
SCYL2 SCY1-like 2 (S. cerevisiae)
SELENBP1 selenium binding protein 1
SLC39A7 solute carrier family 39 (zinc transporter), member 7
SPATA7 spermatogenesis associated 7
STX5 syntaxin 5
TAF15 TAF15 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 68kDa
TAGLN3 transgelin 3
TBL3 transducin (beta)-like 3
TDRD7 tudor domain containing 7
TMEM62 transmembrane protein 62
TPMT thiopurine S-methyltransferase
TPST2 tyrosylprotein sulfotransferase 2
TTPAL tocopherol (alpha) transfer protein-like
UBQLN4 ubiquilin 4
USB1 U6 snRNA biogenesis 1
USP27X ubiquitin specific peptidase 27, X-linked
VPS11 vacuolar protein sorting 11 homolog (S. cerevisiae)
ZBTB10 zinc finger and BTB domain containing 10
ZBTB39 zinc finger and BTB domain containing 39
ZC3H12A zinc finger CCCH-type containing 12A
ZDHHC14 zinc finger, DHHC-type containing 14
ZFP69B ZFP69 zinc finger protein B
ZNF276 zinc finger protein 276
ZNF571 zinc finger protein 571
ZNF668 zinc finger protein 668
ZNHIT2 zinc finger, HIT-type containing 2