replicative senescence Gene Set

Dataset GO Biological Process Annotations 2015
Category structural or functional annotations
Type biological process
Description A cell aging process associated with the dismantling of a cell as a response to telomere shortening and/or cellular aging. (Gene Ontology, GO_0090399)
External Link http://amigo.geneontology.org/amigo/term/GO:0090399
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Genes

11 genes participating in the replicative senescence biological process from the curated GO Biological Process Annotations 2015 dataset.

Symbol Name
ATM ATM serine/threonine kinase
ATR ATR serine/threonine kinase
CDKN2A cyclin-dependent kinase inhibitor 2A
CHEK1 checkpoint kinase 1
CHEK2 checkpoint kinase 2
CTC1 CTS telomere maintenance complex component 1
MME membrane metallo-endopeptidase
PLA2R1 phospholipase A2 receptor 1, 180kDa
TERT telomerase reverse transcriptase
TP53 tumor protein p53
WNT16 wingless-type MMTV integration site family, member 16