rescinnamine-2785 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

197 genes differentially expressed following the rescinnamine-2785 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ABCB9 ATP-binding cassette, sub-family B (MDR/TAP), member 9
ACBD4 acyl-CoA binding domain containing 4
ADGRA2 adhesion G protein-coupled receptor A2
ANGPT4 angiopoietin 4
ARNT aryl hydrocarbon receptor nuclear translocator
ASIC1 acid sensing (proton gated) ion channel 1
ATRNL1 attractin-like 1
BST2 bone marrow stromal cell antigen 2
C2ORF27A chromosome 2 open reading frame 27A
CBFA2T2 core-binding factor, runt domain, alpha subunit 2; translocated to, 2
CBX7 chromobox homolog 7
CD1A CD1a molecule
CD22 CD22 molecule
CHAC1 ChaC glutathione-specific gamma-glutamylcyclotransferase 1
CTSF cathepsin F
CXCL13 chemokine (C-X-C motif) ligand 13
CYLC1 cylicin, basic protein of sperm head cytoskeleton 1
CYLD cylindromatosis (turban tumor syndrome)
DAPK1 death-associated protein kinase 1
DDIT3 DNA-damage-inducible transcript 3
DDIT4 DNA-damage-inducible transcript 4
DDX60 DEAD (Asp-Glu-Ala-Asp) box polypeptide 60
DLGAP4 discs, large (Drosophila) homolog-associated protein 4
DMBT1 deleted in malignant brain tumors 1
DMPK dystrophia myotonica-protein kinase
ERN2 endoplasmic reticulum to nucleus signaling 2
EVA1B eva-1 homolog B (C. elegans)
GABBR1 gamma-aminobutyric acid (GABA) B receptor, 1
GADD45G growth arrest and DNA-damage-inducible, gamma
GPATCH4 G patch domain containing 4
GPR1 G protein-coupled receptor 1
GRB10 growth factor receptor-bound protein 10
GSK3A glycogen synthase kinase 3 alpha
HADHA hydroxyacyl-CoA dehydrogenase/3-ketoacyl-CoA thiolase/enoyl-CoA hydratase (trifunctional protein), alpha subunit
HECW1 HECT, C2 and WW domain containing E3 ubiquitin protein ligase 1
HFE hemochromatosis
HMGCR 3-hydroxy-3-methylglutaryl-CoA reductase
HMGCS1 3-hydroxy-3-methylglutaryl-CoA synthase 1 (soluble)
HS3ST3A1 heparan sulfate (glucosamine) 3-O-sulfotransferase 3A1
HSD17B7 hydroxysteroid (17-beta) dehydrogenase 7
IDI1 isopentenyl-diphosphate delta isomerase 1
IFI27 interferon, alpha-inducible protein 27
IFI6 interferon, alpha-inducible protein 6
IFIT1 interferon-induced protein with tetratricopeptide repeats 1
IFITM1 interferon induced transmembrane protein 1
IL21R interleukin 21 receptor
INHBE inhibin, beta E
INSIG1 insulin induced gene 1
IRF4 interferon regulatory factor 4
IRF9 interferon regulatory factor 9
ISG15 ISG15 ubiquitin-like modifier
ITGA3 integrin, alpha 3 (antigen CD49C, alpha 3 subunit of VLA-3 receptor)
LPIN1 lipin 1
LSS lanosterol synthase (2,3-oxidosqualene-lanosterol cyclase)
MAFF v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog F
MAGOH2P mago-nashi homolog 2, pseudogene
MFSD6 major facilitator superfamily domain containing 6
MSMO1 methylsterol monooxygenase 1
MVD mevalonate (diphospho) decarboxylase
MVK mevalonate kinase
MVP major vault protein
MYOF myoferlin
NEAT1 nuclear paraspeckle assembly transcript 1 (non-protein coding)
NKX3-2 NK3 homeobox 2
NUDT18 nudix (nucleoside diphosphate linked moiety X)-type motif 18
NUPR1 nuclear protein, transcriptional regulator, 1
OAS1 2'-5'-oligoadenylate synthetase 1, 40/46kDa
OAS2 2'-5'-oligoadenylate synthetase 2, 69/71kDa
ONECUT2 one cut homeobox 2
OPTN optineurin
PCK2 phosphoenolpyruvate carboxykinase 2 (mitochondrial)
PLA2G3 phospholipase A2, group III
PPP1R15A protein phosphatase 1, regulatory subunit 15A
PRF1 perforin 1 (pore forming protein)
PTCRA pre T-cell antigen receptor alpha
RARA retinoic acid receptor, alpha
RBP4 retinol binding protein 4, plasma
RGS2 regulator of G-protein signaling 2
RUNX1 runt-related transcription factor 1
SCD stearoyl-CoA desaturase (delta-9-desaturase)
SEMA3B sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3B
SLC1A4 solute carrier family 1 (glutamate/neutral amino acid transporter), member 4
SLC2A5 solute carrier family 2 (facilitated glucose/fructose transporter), member 5
SLC2A6 solute carrier family 2 (facilitated glucose transporter), member 6
SLC48A1 solute carrier family 48 (heme transporter), member 1
SLC7A11 solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11
SLCO4C1 solute carrier organic anion transporter family, member 4C1
SQLE squalene epoxidase
ST3GAL5 ST3 beta-galactoside alpha-2,3-sialyltransferase 5
STAT1 signal transducer and activator of transcription 1, 91kDa
TJAP1 tight junction associated protein 1 (peripheral)
TRBC1 T cell receptor beta constant 1
TSC22D3 TSC22 domain family, member 3
TTC28 tetratricopeptide repeat domain 28
TTLL4 tubulin tyrosine ligase-like family member 4
WSCD1 WSC domain containing 1
ZNF16 zinc finger protein 16
ZNF230 zinc finger protein 230
ZNF589 zinc finger protein 589

decreased expression

Symbol Name
AAR2 AAR2 splicing factor homolog (S. cerevisiae)
ABHD17B abhydrolase domain containing 17B
ACADSB acyl-CoA dehydrogenase, short/branched chain
ACSF2 acyl-CoA synthetase family member 2
ADGRE5 adhesion G protein-coupled receptor E5
AKR1C3 aldo-keto reductase family 1, member C3
AP1S2 adaptor-related protein complex 1, sigma 2 subunit
ARHGDIG Rho GDP dissociation inhibitor (GDI) gamma
ARSB arylsulfatase B
ASAP1-IT1 ASAP1 intronic transcript 1
BCOR BCL6 corepressor
C16ORF59 chromosome 16 open reading frame 59
C22ORF29 chromosome 22 open reading frame 29
C5ORF30 chromosome 5 open reading frame 30
C7ORF43 chromosome 7 open reading frame 43
CCNE1 cyclin E1
CEBPA CCAAT/enhancer binding protein (C/EBP), alpha
CEP97 centrosomal protein 97kDa
CHKB choline kinase beta
CPPED1 calcineurin-like phosphoesterase domain containing 1
CROT carnitine O-octanoyltransferase
CWF19L1 CWF19-like 1, cell cycle control (S. pombe)
CYP20A1 cytochrome P450, family 20, subfamily A, polypeptide 1
CYP26A1 cytochrome P450, family 26, subfamily A, polypeptide 1
DNAJC24 DnaJ (Hsp40) homolog, subfamily C, member 24
DNAL4 dynein, axonemal, light chain 4
DUSP2 dual specificity phosphatase 2
E2F8 E2F transcription factor 8
EFNA3 ephrin-A3
EHD3 EH-domain containing 3
EPN3 epsin 3
FAM204A family with sequence similarity 204, member A
FOXC1 forkhead box C1
GAMT guanidinoacetate N-methyltransferase
GJA1 gap junction protein, alpha 1, 43kDa
HTR1E 5-hydroxytryptamine (serotonin) receptor 1E, G protein-coupled
IFT22 intraflagellar transport 22
IL17RB interleukin 17 receptor B
JAK2 Janus kinase 2
KCNN4 potassium channel, calcium activated intermediate/small conductance subfamily N alpha, member 4
KDM7A lysine (K)-specific demethylase 7A
KRI1 KRI1 homolog (S. cerevisiae)
LY6D lymphocyte antigen 6 complex, locus D
LZTR1 leucine-zipper-like transcription regulator 1
MAP2K3 mitogen-activated protein kinase kinase 3
MCOLN1 mucolipin 1
MGA MGA, MAX dimerization protein
MGC12488
MSMB microseminoprotein, beta-
MUM1 melanoma associated antigen (mutated) 1
NFE2L3 nuclear factor, erythroid 2-like 3
NIPAL2 NIPA-like domain containing 2
NOD1 nucleotide-binding oligomerization domain containing 1
NPFFR1 neuropeptide FF receptor 1
NPY1R neuropeptide Y receptor Y1
NPY5R neuropeptide Y receptor Y5
NRGN neurogranin (protein kinase C substrate, RC3)
NT5DC3 5'-nucleotidase domain containing 3
NT5E 5'-nucleotidase, ecto (CD73)
PDZK1 PDZ domain containing 1
PIGN phosphatidylinositol glycan anchor biosynthesis, class N
POR P450 (cytochrome) oxidoreductase
PPIP5K1 diphosphoinositol pentakisphosphate kinase 1
QSER1 glutamine and serine rich 1
RAB30 RAB30, member RAS oncogene family
RHOBTB2 Rho-related BTB domain containing 2
RHPN1-AS1 RHPN1 antisense RNA 1 (head to head)
ROBO1 roundabout, axon guidance receptor, homolog 1 (Drosophila)
RPS6KA4 ribosomal protein S6 kinase, 90kDa, polypeptide 4
SAYSD1 SAYSVFN motif domain containing 1
SEC61A2 Sec61 alpha 2 subunit (S. cerevisiae)
SERPINA5 serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 5
SERPINF1 serpin peptidase inhibitor, clade F (alpha-2 antiplasmin, pigment epithelium derived factor), member 1
SGK1 serum/glucocorticoid regulated kinase 1
SLC22A18 solute carrier family 22, member 18
SLC39A7 solute carrier family 39 (zinc transporter), member 7
SLC8B1 solute carrier family 8 (sodium/lithium/calcium exchanger), member B1
SOCS6 suppressor of cytokine signaling 6
SPINK4 serine peptidase inhibitor, Kazal type 4
SPRYD7 SPRY domain containing 7
STARD13 StAR-related lipid transfer (START) domain containing 13
STK16 serine/threonine kinase 16
SULT2B1 sulfotransferase family, cytosolic, 2B, member 1
SUV39H2 suppressor of variegation 3-9 homolog 2 (Drosophila)
TFAP4 transcription factor AP-4 (activating enhancer binding protein 4)
TGFB3 transforming growth factor, beta 3
TMPRSS3 transmembrane protease, serine 3
TNS2 tensin 2
TRMT13 tRNA methyltransferase 13 homolog (S. cerevisiae)
TRMT61A tRNA methyltransferase 61A
TRMU tRNA 5-methylaminomethyl-2-thiouridylate methyltransferase
VEZT vezatin, adherens junctions transmembrane protein
ZNF211 zinc finger protein 211
ZNF282 zinc finger protein 282
ZNF492 zinc finger protein 492
ZNF532 zinc finger protein 532
ZNF665 zinc finger protein 665
ZNF696 zinc finger protein 696