reserpine-3003 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

199 genes differentially expressed following the reserpine-3003 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ALDH1B1 aldehyde dehydrogenase 1 family, member B1
ANG angiogenin, ribonuclease, RNase A family, 5
ARAP1 ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 1
ASAP3 ArfGAP with SH3 domain, ankyrin repeat and PH domain 3
ATP2B3 ATPase, Ca++ transporting, plasma membrane 3
C1QTNF1 C1q and tumor necrosis factor related protein 1
C21ORF2 chromosome 21 open reading frame 2
CALB1 calbindin 1, 28kDa
CCL11 chemokine (C-C motif) ligand 11
CD22 CD22 molecule
CD300C CD300c molecule
CEACAM4 carcinoembryonic antigen-related cell adhesion molecule 4
CEACAM7 carcinoembryonic antigen-related cell adhesion molecule 7
CX3CL1 chemokine (C-X3-C motif) ligand 1
CYP2D6 cytochrome P450, family 2, subfamily D, polypeptide 6
DGCR8 DGCR8 microprocessor complex subunit
DOCK5 dedicator of cytokinesis 5
EPHB2 EPH receptor B2
EPM2A epilepsy, progressive myoclonus type 2A, Lafora disease (laforin)
EPN3 epsin 3
EVA1B eva-1 homolog B (C. elegans)
EXOSC2 exosome component 2
EXPH5 exophilin 5
FGF9 fibroblast growth factor 9
FJX1 four jointed box 1 (Drosophila)
FSHB follicle stimulating hormone, beta polypeptide
GRIK5 glutamate receptor, ionotropic, kainate 5
HFE hemochromatosis
HOXC4 homeobox C4
HOXD10 homeobox D10
HSF2BP heat shock transcription factor 2 binding protein
HUWE1 HECT, UBA and WWE domain containing 1, E3 ubiquitin protein ligase
HYI hydroxypyruvate isomerase (putative)
ICOSLG inducible T-cell co-stimulator ligand
IFNA21 interferon, alpha 21
IL24 interleukin 24
IRF4 interferon regulatory factor 4
ITGA2B integrin, alpha 2b (platelet glycoprotein IIb of IIb/IIIa complex, antigen CD41)
ITGBL1 integrin, beta-like 1 (with EGF-like repeat domains)
KIAA0895 KIAA0895
KIF24 kinesin family member 24
KLF6 Kruppel-like factor 6
KLHL18 kelch-like family member 18
LMOD1 leiomodin 1 (smooth muscle)
MLF1 myeloid leukemia factor 1
MMP14 matrix metallopeptidase 14 (membrane-inserted)
MS4A4A membrane-spanning 4-domains, subfamily A, member 4A
MST1R macrophage stimulating 1 receptor
MYH11 myosin, heavy chain 11, smooth muscle
MYRF myelin regulatory factor
NBR2 neighbor of BRCA1 gene 2 (non-protein coding)
NCKIPSD NCK interacting protein with SH3 domain
NDUFA2 NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 2, 8kDa
NOP16 NOP16 nucleolar protein
NR4A2 nuclear receptor subfamily 4, group A, member 2
NR4A3 nuclear receptor subfamily 4, group A, member 3
NR5A2 nuclear receptor subfamily 5, group A, member 2
OXTR oxytocin receptor
PAGE1 P antigen family, member 1 (prostate associated)
PALLD palladin, cytoskeletal associated protein
PCSK5 proprotein convertase subtilisin/kexin type 5
PDE1C phosphodiesterase 1C, calmodulin-dependent 70kDa
POLL polymerase (DNA directed), lambda
PPL periplakin
PPP1R3A protein phosphatase 1, regulatory subunit 3A
RAB26 RAB26, member RAS oncogene family
RASAL2 RAS protein activator like 2
RNF122 ring finger protein 122
RNF39 ring finger protein 39
SCAND2P SCAN domain containing 2 pseudogene
SCIN scinderin
SEZ6L seizure related 6 homolog (mouse)-like
SGCB sarcoglycan, beta (43kDa dystrophin-associated glycoprotein)
SGCD sarcoglycan, delta (35kDa dystrophin-associated glycoprotein)
SH3TC1 SH3 domain and tetratricopeptide repeats 1
SHOX2 short stature homeobox 2
SLC5A1 solute carrier family 5 (sodium/glucose cotransporter), member 1
SNAPC2 small nuclear RNA activating complex, polypeptide 2, 45kDa
SPHK2 sphingosine kinase 2
SRCAP Snf2-related CREBBP activator protein
SSPN sarcospan
STARD5 StAR-related lipid transfer (START) domain containing 5
STK38 serine/threonine kinase 38
STRA6 stimulated by retinoic acid 6
SULT4A1 sulfotransferase family 4A, member 1
TAS2R4 taste receptor, type 2, member 4
TAT tyrosine aminotransferase
THBS1 thrombospondin 1
TMEM257 transmembrane protein 257
TNFRSF12A tumor necrosis factor receptor superfamily, member 12A
TRIM49 tripartite motif containing 49
TSPAN2 tetraspanin 2
VGF VGF nerve growth factor inducible
ZBTB20 zinc finger and BTB domain containing 20
ZC3H13 zinc finger CCCH-type containing 13
ZFP36L1 ZFP36 ring finger protein-like 1
ZNF214 zinc finger protein 214
ZNF287 zinc finger protein 287
ZNF646 zinc finger protein 646

decreased expression

Symbol Name
ABHD17B abhydrolase domain containing 17B
ACPP acid phosphatase, prostate
ADGB androglobin
AIM2 absent in melanoma 2
ALDOAP2 aldolase A, fructose-bisphosphate pseudogene 2
APBB1IP amyloid beta (A4) precursor protein-binding, family B, member 1 interacting protein
ARAP3 ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 3
ARHGEF10L Rho guanine nucleotide exchange factor (GEF) 10-like
ATG9A autophagy related 9A
BIK BCL2-interacting killer (apoptosis-inducing)
BIRC3 baculoviral IAP repeat containing 3
BTBD2 BTB (POZ) domain containing 2
C3ORF18 chromosome 3 open reading frame 18
C8A complement component 8, alpha polypeptide
CARF calcium responsive transcription factor
CCDC71 coiled-coil domain containing 71
CCDC85C coiled-coil domain containing 85C
CCRN4L CCR4 carbon catabolite repression 4-like (S. cerevisiae)
CD82 CD82 molecule
CDK6 cyclin-dependent kinase 6
CEP295 centrosomal protein 295kDa
CHRNB1 cholinergic receptor, nicotinic, beta 1 (muscle)
CISH cytokine inducible SH2-containing protein
CLCN5 chloride channel, voltage-sensitive 5
CNR2 cannabinoid receptor 2 (macrophage)
CSGALNACT1 chondroitin sulfate N-acetylgalactosaminyltransferase 1
CTNNBIP1 catenin, beta interacting protein 1
DDX6 DEAD (Asp-Glu-Ala-Asp) box helicase 6
DHRS3 dehydrogenase/reductase (SDR family) member 3
DOLK dolichol kinase
ECI2 enoyl-CoA delta isomerase 2
ELP6 elongator acetyltransferase complex subunit 6
ENTPD6 ectonucleoside triphosphate diphosphohydrolase 6 (putative)
EPHX1 epoxide hydrolase 1, microsomal (xenobiotic)
EYA3 EYA transcriptional coactivator and phosphatase 3
FAM106A family with sequence similarity 106, member A
FBXL2 F-box and leucine-rich repeat protein 2
FGL2 fibrinogen-like 2
GABRP gamma-aminobutyric acid (GABA) A receptor, pi
GIPC1 GIPC PDZ domain containing family, member 1
GNRH1 gonadotropin-releasing hormone 1 (luteinizing-releasing hormone)
GPATCH2L G patch domain containing 2-like
GPR27 G protein-coupled receptor 27
GSDMD gasdermin D
GSTA4 glutathione S-transferase alpha 4
HDAC7 histone deacetylase 7
HIST1H1T histone cluster 1, H1t
HIST1H2AJ histone cluster 1, H2aj
HOXB9 homeobox B9
IFIT1 interferon-induced protein with tetratricopeptide repeats 1
IFT81 intraflagellar transport 81
IGH immunoglobulin heavy locus
KCNA3 potassium channel, voltage gated shaker related subfamily A, member 3
KIF1B kinesin family member 1B
LATS1 large tumor suppressor kinase 1
LOC100287590 uncharacterized LOC100287590
LRP5 low density lipoprotein receptor-related protein 5
LRP5L low density lipoprotein receptor-related protein 5-like
LSM14B LSM14B, SCD6 homolog B (S. cerevisiae)
LTBP2 latent transforming growth factor beta binding protein 2
LY6E lymphocyte antigen 6 complex, locus E
MLYCD malonyl-CoA decarboxylase
MTERF4 mitochondrial transcription termination factor 4
MTSS1L metastasis suppressor 1-like
MUC6 mucin 6, oligomeric mucus/gel-forming
NLGN1 neuroligin 1
NMUR1 neuromedin U receptor 1
NOD1 nucleotide-binding oligomerization domain containing 1
OLR1 oxidized low density lipoprotein (lectin-like) receptor 1
PECR peroxisomal trans-2-enoyl-CoA reductase
PITPNM1 phosphatidylinositol transfer protein, membrane-associated 1
PLAT plasminogen activator, tissue
PLCB3 phospholipase C, beta 3 (phosphatidylinositol-specific)
PRO2964 uncharacterized protein PRO2964
PRR4 proline rich 4 (lacrimal)
RAB23 RAB23, member RAS oncogene family
RAB3IL1 RAB3A interacting protein (rabin3)-like 1
RBM12B-AS1 RBM12B antisense RNA 1
SCAMP4 secretory carrier membrane protein 4
SEMA3G sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3G
SERPINB10 serpin peptidase inhibitor, clade B (ovalbumin), member 10
SEZ6L2 seizure related 6 homolog (mouse)-like 2
SLC16A4 solute carrier family 16, member 4
SLC16A6 solute carrier family 16, member 6
SLC44A1 solute carrier family 44 (choline transporter), member 1
SLITRK5 SLIT and NTRK-like family, member 5
SMUG1 single-strand-selective monofunctional uracil-DNA glycosylase 1
SPAG1 sperm associated antigen 1
SPATA2L spermatogenesis associated 2-like
SUPT3H suppressor of Ty 3 homolog (S. cerevisiae)
TAF13 TAF13 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 18kDa
TANC2 tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 2
TGM5 transglutaminase 5
TLR8 toll-like receptor 8
TOM1 target of myb1 (chicken)
VNN1 vanin 1
VPS11 vacuolar protein sorting 11 homolog (S. cerevisiae)
ZKSCAN8 zinc finger with KRAB and SCAN domains 8
ZNF81 zinc finger protein 81
ZSCAN31 zinc finger and SCAN domain containing 31