| Dataset | CMAP Signatures of Differentially Expressed Genes for Small Molecules |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis) |
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197 genes differentially expressed following the reserpine-3341 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
| Symbol | Name |
|---|---|
| ADAM18 | ADAM metallopeptidase domain 18 |
| ADGRA2 | adhesion G protein-coupled receptor A2 |
| ALDH3B2 | aldehyde dehydrogenase 3 family, member B2 |
| ARR3 | arrestin 3, retinal (X-arrestin) |
| ATF6 | activating transcription factor 6 |
| BCAM | basal cell adhesion molecule (Lutheran blood group) |
| BCO1 | beta-carotene oxygenase 1 |
| BDKRB2 | bradykinin receptor B2 |
| C11ORF21 | chromosome 11 open reading frame 21 |
| C22ORF46 | chromosome 22 open reading frame 46 |
| CCDC64 | coiled-coil domain containing 64 |
| CCZ1 | CCZ1 vacuolar protein trafficking and biogenesis associated homolog (S. cerevisiae) |
| CDH6 | cadherin 6, type 2, K-cadherin (fetal kidney) |
| CES3 | carboxylesterase 3 |
| CHAC1 | ChaC glutathione-specific gamma-glutamylcyclotransferase 1 |
| CHRNA6 | cholinergic receptor, nicotinic, alpha 6 (neuronal) |
| CLTA | clathrin, light chain A |
| CNGB3 | cyclic nucleotide gated channel beta 3 |
| COL14A1 | collagen, type XIV, alpha 1 |
| CTIF | CBP80/20-dependent translation initiation factor |
| CYHR1 | cysteine/histidine-rich 1 |
| DDIT4 | DNA-damage-inducible transcript 4 |
| DEF6 | differentially expressed in FDCP 6 homolog (mouse) |
| DLK2 | delta-like 2 homolog (Drosophila) |
| DLX2 | distal-less homeobox 2 |
| DNAH17 | dynein, axonemal, heavy chain 17 |
| DNASE1L3 | deoxyribonuclease I-like 3 |
| FCGR3B | Fc fragment of IgG, low affinity IIIb, receptor (CD16b) |
| FHL1 | four and a half LIM domains 1 |
| FLT3LG | fms-related tyrosine kinase 3 ligand |
| FN1 | fibronectin 1 |
| GAS7 | growth arrest-specific 7 |
| GIMAP6 | GTPase, IMAP family member 6 |
| GK | glycerol kinase |
| GNAT2 | guanine nucleotide binding protein (G protein), alpha transducing activity polypeptide 2 |
| GPLD1 | glycosylphosphatidylinositol specific phospholipase D1 |
| GPR3 | G protein-coupled receptor 3 |
| GPRIN2 | G protein regulated inducer of neurite outgrowth 2 |
| HDLBP | high density lipoprotein binding protein |
| HFE | hemochromatosis |
| HHAT | hedgehog acyltransferase |
| HIPK3 | homeodomain interacting protein kinase 3 |
| HNRNPA3P1 | heterogeneous nuclear ribonucleoprotein A3 pseudogene 1 |
| HTR1B | 5-hydroxytryptamine (serotonin) receptor 1B, G protein-coupled |
| ISG20L2 | interferon stimulated exonuclease gene 20kDa-like 2 |
| JMJD6 | jumonji domain containing 6 |
| KCNA6 | potassium channel, voltage gated shaker related subfamily A, member 6 |
| KHDRBS2 | KH domain containing, RNA binding, signal transduction associated 2 |
| KIAA0195 | KIAA0195 |
| KLK13 | kallikrein-related peptidase 13 |
| KRT6B | keratin 6B, type II |
| LEPR | leptin receptor |
| LILRB3 | leukocyte immunoglobulin-like receptor, subfamily B (with TM and ITIM domains), member 3 |
| LIMD1 | LIM domains containing 1 |
| LINC00652 | long intergenic non-protein coding RNA 652 |
| MBD2 | methyl-CpG binding domain protein 2 |
| MEF2D | myocyte enhancer factor 2D |
| MST1L | macrophage stimulating 1-like |
| MTMR8 | myotubularin related protein 8 |
| N4BP2L2-IT2 | N4BPL2 intronic transcript 2 |
| NCOR2 | nuclear receptor corepressor 2 |
| NF2 | neurofibromin 2 (merlin) |
| NR6A1 | nuclear receptor subfamily 6, group A, member 1 |
| NUPR1 | nuclear protein, transcriptional regulator, 1 |
| PARP3 | poly (ADP-ribose) polymerase family, member 3 |
| PCDHA9 | protocadherin alpha 9 |
| PCLO | piccolo presynaptic cytomatrix protein |
| PHLDA1 | pleckstrin homology-like domain, family A, member 1 |
| PMS2P3 | postmeiotic segregation increased 2 pseudogene 3 |
| PRDM5 | PR domain containing 5 |
| PRSS2 | protease, serine, 2 (trypsin 2) |
| RAB6B | RAB6B, member RAS oncogene family |
| RAD52 | RAD52 homolog (S. cerevisiae) |
| RBP4 | retinol binding protein 4, plasma |
| REM1 | RAS (RAD and GEM)-like GTP-binding 1 |
| RIMS2 | regulating synaptic membrane exocytosis 2 |
| RND1 | Rho family GTPase 1 |
| RUNX1 | runt-related transcription factor 1 |
| SEMA3G | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3G |
| SFI1 | Sfi1 homolog, spindle assembly associated (yeast) |
| SLC1A4 | solute carrier family 1 (glutamate/neutral amino acid transporter), member 4 |
| SLC5A2 | solute carrier family 5 (sodium/glucose cotransporter), member 2 |
| SLC7A11 | solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11 |
| SNCA | synuclein, alpha (non A4 component of amyloid precursor) |
| SOS2 | son of sevenless homolog 2 (Drosophila) |
| SPAG8 | sperm associated antigen 8 |
| SPDEF | SAM pointed domain containing ETS transcription factor |
| SSX1 | synovial sarcoma, X breakpoint 1 |
| SYT2 | synaptotagmin II |
| TAAR5 | trace amine associated receptor 5 |
| TBX3 | T-box 3 |
| TDRKH | tudor and KH domain containing |
| TIMP3 | TIMP metallopeptidase inhibitor 3 |
| TSPAN9 | tetraspanin 9 |
| TXNIP | thioredoxin interacting protein |
| UGT2B15 | UDP glucuronosyltransferase 2 family, polypeptide B15 |
| UPK3A | uroplakin 3A |
| WSB1 | WD repeat and SOCS box containing 1 |
| ZNF155 | zinc finger protein 155 |
| ZNF236 | zinc finger protein 236 |
| Symbol | Name |
|---|---|
| ABLIM3 | actin binding LIM protein family, member 3 |
| ACAD10 | acyl-CoA dehydrogenase family, member 10 |
| ADGRL2 | adhesion G protein-coupled receptor L2 |
| AFAP1 | actin filament associated protein 1 |
| ALPK1 | alpha-kinase 1 |
| ANXA2P3 | annexin A2 pseudogene 3 |
| APLP1 | amyloid beta (A4) precursor-like protein 1 |
| ARFGAP1 | ADP-ribosylation factor GTPase activating protein 1 |
| ARHGEF5 | Rho guanine nucleotide exchange factor (GEF) 5 |
| ARVCF | armadillo repeat gene deleted in velocardiofacial syndrome |
| B3GALT4 | UDP-Gal:betaGlcNAc beta 1,3-galactosyltransferase, polypeptide 4 |
| B4GALT2 | UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 2 |
| BFSP1 | beaded filament structural protein 1, filensin |
| C11ORF95 | chromosome 11 open reading frame 95 |
| C4ORF29 | chromosome 4 open reading frame 29 |
| CACNA1H | calcium channel, voltage-dependent, T type, alpha 1H subunit |
| CASD1 | CAS1 domain containing 1 |
| CCNK | cyclin K |
| CEP97 | centrosomal protein 97kDa |
| CHML | choroideremia-like (Rab escort protein 2) |
| CPSF4 | cleavage and polyadenylation specific factor 4, 30kDa |
| CRY2 | cryptochrome circadian clock 2 |
| CST6 | cystatin E/M |
| CUEDC1 | CUE domain containing 1 |
| CYP20A1 | cytochrome P450, family 20, subfamily A, polypeptide 1 |
| CYP4F12 | cytochrome P450, family 4, subfamily F, polypeptide 12 |
| DCAF13 | DDB1 and CUL4 associated factor 13 |
| DGCR11 | DiGeorge syndrome critical region gene 11 (non-protein coding) |
| DNAJB2 | DnaJ (Hsp40) homolog, subfamily B, member 2 |
| DNMT3A | DNA (cytosine-5-)-methyltransferase 3 alpha |
| EFNA3 | ephrin-A3 |
| ENO3 | enolase 3 (beta, muscle) |
| FGD1 | FYVE, RhoGEF and PH domain containing 1 |
| FGL1 | fibrinogen-like 1 |
| FOXI1 | forkhead box I1 |
| GLS2 | glutaminase 2 (liver, mitochondrial) |
| GLTSCR1 | glioma tumor suppressor candidate region gene 1 |
| GUSBP3 | glucuronidase, beta pseudogene 3 |
| HERC6 | HECT and RLD domain containing E3 ubiquitin protein ligase family member 6 |
| HIRA | histone cell cycle regulator |
| HIST1H2AI | histone cluster 1, H2ai |
| HIST2H2AA3 | histone cluster 2, H2aa3 |
| HIVEP3 | human immunodeficiency virus type I enhancer binding protein 3 |
| HYAL2 | hyaluronoglucosaminidase 2 |
| IFNAR2 | interferon (alpha, beta and omega) receptor 2 |
| IL17RA | interleukin 17 receptor A |
| IL17RB | interleukin 17 receptor B |
| KIAA0319L | KIAA0319-like |
| KIF15 | kinesin family member 15 |
| LHX1 | LIM homeobox 1 |
| LNPEP | leucyl/cystinyl aminopeptidase |
| MAST3 | microtubule associated serine/threonine kinase 3 |
| MTERF4 | mitochondrial transcription termination factor 4 |
| NPFFR1 | neuropeptide FF receptor 1 |
| NPY1R | neuropeptide Y receptor Y1 |
| NT5DC3 | 5'-nucleotidase domain containing 3 |
| PADI1 | peptidyl arginine deiminase, type I |
| PCDHA6 | protocadherin alpha 6 |
| PCDHB8 | protocadherin beta 8 |
| PITPNM1 | phosphatidylinositol transfer protein, membrane-associated 1 |
| PLEKHA6 | pleckstrin homology domain containing, family A member 6 |
| PODXL2 | podocalyxin-like 2 |
| PPM1G | protein phosphatase, Mg2+/Mn2+ dependent, 1G |
| PRR4 | proline rich 4 (lacrimal) |
| RAD54L2 | RAD54-like 2 (S. cerevisiae) |
| RIBC2 | RIB43A domain with coiled-coils 2 |
| RPL23AP32 | ribosomal protein L23a pseudogene 32 |
| S100A9 | S100 calcium binding protein A9 |
| SCGB2A2 | secretoglobin, family 2A, member 2 |
| SDC3 | syndecan 3 |
| SEMA4A | sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4A |
| SETD6 | SET domain containing 6 |
| SMEK2 | SMEK homolog 2, suppressor of mek1 (Dictyostelium) |
| SMG1 | SMG1 phosphatidylinositol 3-kinase-related kinase |
| STAG3 | stromal antigen 3 |
| TBC1D17 | TBC1 domain family, member 17 |
| TBC1D2 | TBC1 domain family, member 2 |
| TGFBRAP1 | transforming growth factor, beta receptor associated protein 1 |
| THBS3 | thrombospondin 3 |
| TICAM1 | toll-like receptor adaptor molecule 1 |
| TLR5 | toll-like receptor 5 |
| TMEM121 | transmembrane protein 121 |
| TMEM127 | transmembrane protein 127 |
| TMEM2 | transmembrane protein 2 |
| TMEM242 | transmembrane protein 242 |
| TRAF5 | TNF receptor-associated factor 5 |
| TXLNA | taxilin alpha |
| URB2 | URB2 ribosome biogenesis 2 homolog (S. cerevisiae) |
| WDR33 | WD repeat domain 33 |
| XRCC3 | X-ray repair complementing defective repair in Chinese hamster cells 3 |
| YIF1B | Yip1 interacting factor homolog B (S. cerevisiae) |
| ZAK | sterile alpha motif and leucine zipper containing kinase AZK |
| ZBTB22 | zinc finger and BTB domain containing 22 |
| ZNF23 | zinc finger protein 23 |
| ZNF268 | zinc finger protein 268 |
| ZNF282 | zinc finger protein 282 |
| ZNF37BP | zinc finger protein 37B, pseudogene |