reserpine-3341 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

197 genes differentially expressed following the reserpine-3341 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ADAM18 ADAM metallopeptidase domain 18
ADGRA2 adhesion G protein-coupled receptor A2
ALDH3B2 aldehyde dehydrogenase 3 family, member B2
ARR3 arrestin 3, retinal (X-arrestin)
ATF6 activating transcription factor 6
BCAM basal cell adhesion molecule (Lutheran blood group)
BCO1 beta-carotene oxygenase 1
BDKRB2 bradykinin receptor B2
C11ORF21 chromosome 11 open reading frame 21
C22ORF46 chromosome 22 open reading frame 46
CCDC64 coiled-coil domain containing 64
CCZ1 CCZ1 vacuolar protein trafficking and biogenesis associated homolog (S. cerevisiae)
CDH6 cadherin 6, type 2, K-cadherin (fetal kidney)
CES3 carboxylesterase 3
CHAC1 ChaC glutathione-specific gamma-glutamylcyclotransferase 1
CHRNA6 cholinergic receptor, nicotinic, alpha 6 (neuronal)
CLTA clathrin, light chain A
CNGB3 cyclic nucleotide gated channel beta 3
COL14A1 collagen, type XIV, alpha 1
CTIF CBP80/20-dependent translation initiation factor
CYHR1 cysteine/histidine-rich 1
DDIT4 DNA-damage-inducible transcript 4
DEF6 differentially expressed in FDCP 6 homolog (mouse)
DLK2 delta-like 2 homolog (Drosophila)
DLX2 distal-less homeobox 2
DNAH17 dynein, axonemal, heavy chain 17
DNASE1L3 deoxyribonuclease I-like 3
FCGR3B Fc fragment of IgG, low affinity IIIb, receptor (CD16b)
FHL1 four and a half LIM domains 1
FLT3LG fms-related tyrosine kinase 3 ligand
FN1 fibronectin 1
GAS7 growth arrest-specific 7
GIMAP6 GTPase, IMAP family member 6
GK glycerol kinase
GNAT2 guanine nucleotide binding protein (G protein), alpha transducing activity polypeptide 2
GPLD1 glycosylphosphatidylinositol specific phospholipase D1
GPR3 G protein-coupled receptor 3
GPRIN2 G protein regulated inducer of neurite outgrowth 2
HDLBP high density lipoprotein binding protein
HFE hemochromatosis
HHAT hedgehog acyltransferase
HIPK3 homeodomain interacting protein kinase 3
HNRNPA3P1 heterogeneous nuclear ribonucleoprotein A3 pseudogene 1
HTR1B 5-hydroxytryptamine (serotonin) receptor 1B, G protein-coupled
ISG20L2 interferon stimulated exonuclease gene 20kDa-like 2
JMJD6 jumonji domain containing 6
KCNA6 potassium channel, voltage gated shaker related subfamily A, member 6
KHDRBS2 KH domain containing, RNA binding, signal transduction associated 2
KIAA0195 KIAA0195
KLK13 kallikrein-related peptidase 13
KRT6B keratin 6B, type II
LEPR leptin receptor
LILRB3 leukocyte immunoglobulin-like receptor, subfamily B (with TM and ITIM domains), member 3
LIMD1 LIM domains containing 1
LINC00652 long intergenic non-protein coding RNA 652
MBD2 methyl-CpG binding domain protein 2
MEF2D myocyte enhancer factor 2D
MST1L macrophage stimulating 1-like
MTMR8 myotubularin related protein 8
N4BP2L2-IT2 N4BPL2 intronic transcript 2
NCOR2 nuclear receptor corepressor 2
NF2 neurofibromin 2 (merlin)
NR6A1 nuclear receptor subfamily 6, group A, member 1
NUPR1 nuclear protein, transcriptional regulator, 1
PARP3 poly (ADP-ribose) polymerase family, member 3
PCDHA9 protocadherin alpha 9
PCLO piccolo presynaptic cytomatrix protein
PHLDA1 pleckstrin homology-like domain, family A, member 1
PMS2P3 postmeiotic segregation increased 2 pseudogene 3
PRDM5 PR domain containing 5
PRSS2 protease, serine, 2 (trypsin 2)
RAB6B RAB6B, member RAS oncogene family
RAD52 RAD52 homolog (S. cerevisiae)
RBP4 retinol binding protein 4, plasma
REM1 RAS (RAD and GEM)-like GTP-binding 1
RIMS2 regulating synaptic membrane exocytosis 2
RND1 Rho family GTPase 1
RUNX1 runt-related transcription factor 1
SEMA3G sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3G
SFI1 Sfi1 homolog, spindle assembly associated (yeast)
SLC1A4 solute carrier family 1 (glutamate/neutral amino acid transporter), member 4
SLC5A2 solute carrier family 5 (sodium/glucose cotransporter), member 2
SLC7A11 solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11
SNCA synuclein, alpha (non A4 component of amyloid precursor)
SOS2 son of sevenless homolog 2 (Drosophila)
SPAG8 sperm associated antigen 8
SPDEF SAM pointed domain containing ETS transcription factor
SSX1 synovial sarcoma, X breakpoint 1
SYT2 synaptotagmin II
TAAR5 trace amine associated receptor 5
TBX3 T-box 3
TDRKH tudor and KH domain containing
TIMP3 TIMP metallopeptidase inhibitor 3
TSPAN9 tetraspanin 9
TXNIP thioredoxin interacting protein
UGT2B15 UDP glucuronosyltransferase 2 family, polypeptide B15
UPK3A uroplakin 3A
WSB1 WD repeat and SOCS box containing 1
ZNF155 zinc finger protein 155
ZNF236 zinc finger protein 236

decreased expression

Symbol Name
ABLIM3 actin binding LIM protein family, member 3
ACAD10 acyl-CoA dehydrogenase family, member 10
ADGRL2 adhesion G protein-coupled receptor L2
AFAP1 actin filament associated protein 1
ALPK1 alpha-kinase 1
ANXA2P3 annexin A2 pseudogene 3
APLP1 amyloid beta (A4) precursor-like protein 1
ARFGAP1 ADP-ribosylation factor GTPase activating protein 1
ARHGEF5 Rho guanine nucleotide exchange factor (GEF) 5
ARVCF armadillo repeat gene deleted in velocardiofacial syndrome
B3GALT4 UDP-Gal:betaGlcNAc beta 1,3-galactosyltransferase, polypeptide 4
B4GALT2 UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 2
BFSP1 beaded filament structural protein 1, filensin
C11ORF95 chromosome 11 open reading frame 95
C4ORF29 chromosome 4 open reading frame 29
CACNA1H calcium channel, voltage-dependent, T type, alpha 1H subunit
CASD1 CAS1 domain containing 1
CCNK cyclin K
CEP97 centrosomal protein 97kDa
CHML choroideremia-like (Rab escort protein 2)
CPSF4 cleavage and polyadenylation specific factor 4, 30kDa
CRY2 cryptochrome circadian clock 2
CST6 cystatin E/M
CUEDC1 CUE domain containing 1
CYP20A1 cytochrome P450, family 20, subfamily A, polypeptide 1
CYP4F12 cytochrome P450, family 4, subfamily F, polypeptide 12
DCAF13 DDB1 and CUL4 associated factor 13
DGCR11 DiGeorge syndrome critical region gene 11 (non-protein coding)
DNAJB2 DnaJ (Hsp40) homolog, subfamily B, member 2
DNMT3A DNA (cytosine-5-)-methyltransferase 3 alpha
EFNA3 ephrin-A3
ENO3 enolase 3 (beta, muscle)
FGD1 FYVE, RhoGEF and PH domain containing 1
FGL1 fibrinogen-like 1
FOXI1 forkhead box I1
GLS2 glutaminase 2 (liver, mitochondrial)
GLTSCR1 glioma tumor suppressor candidate region gene 1
GUSBP3 glucuronidase, beta pseudogene 3
HERC6 HECT and RLD domain containing E3 ubiquitin protein ligase family member 6
HIRA histone cell cycle regulator
HIST1H2AI histone cluster 1, H2ai
HIST2H2AA3 histone cluster 2, H2aa3
HIVEP3 human immunodeficiency virus type I enhancer binding protein 3
HYAL2 hyaluronoglucosaminidase 2
IFNAR2 interferon (alpha, beta and omega) receptor 2
IL17RA interleukin 17 receptor A
IL17RB interleukin 17 receptor B
KIAA0319L KIAA0319-like
KIF15 kinesin family member 15
LHX1 LIM homeobox 1
LNPEP leucyl/cystinyl aminopeptidase
MAST3 microtubule associated serine/threonine kinase 3
MTERF4 mitochondrial transcription termination factor 4
NPFFR1 neuropeptide FF receptor 1
NPY1R neuropeptide Y receptor Y1
NT5DC3 5'-nucleotidase domain containing 3
PADI1 peptidyl arginine deiminase, type I
PCDHA6 protocadherin alpha 6
PCDHB8 protocadherin beta 8
PITPNM1 phosphatidylinositol transfer protein, membrane-associated 1
PLEKHA6 pleckstrin homology domain containing, family A member 6
PODXL2 podocalyxin-like 2
PPM1G protein phosphatase, Mg2+/Mn2+ dependent, 1G
PRR4 proline rich 4 (lacrimal)
RAD54L2 RAD54-like 2 (S. cerevisiae)
RIBC2 RIB43A domain with coiled-coils 2
RPL23AP32 ribosomal protein L23a pseudogene 32
S100A9 S100 calcium binding protein A9
SCGB2A2 secretoglobin, family 2A, member 2
SDC3 syndecan 3
SEMA4A sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4A
SETD6 SET domain containing 6
SMEK2 SMEK homolog 2, suppressor of mek1 (Dictyostelium)
SMG1 SMG1 phosphatidylinositol 3-kinase-related kinase
STAG3 stromal antigen 3
TBC1D17 TBC1 domain family, member 17
TBC1D2 TBC1 domain family, member 2
TGFBRAP1 transforming growth factor, beta receptor associated protein 1
THBS3 thrombospondin 3
TICAM1 toll-like receptor adaptor molecule 1
TLR5 toll-like receptor 5
TMEM121 transmembrane protein 121
TMEM127 transmembrane protein 127
TMEM2 transmembrane protein 2
TMEM242 transmembrane protein 242
TRAF5 TNF receptor-associated factor 5
TXLNA taxilin alpha
URB2 URB2 ribosome biogenesis 2 homolog (S. cerevisiae)
WDR33 WD repeat domain 33
XRCC3 X-ray repair complementing defective repair in Chinese hamster cells 3
YIF1B Yip1 interacting factor homolog B (S. cerevisiae)
ZAK sterile alpha motif and leucine zipper containing kinase AZK
ZBTB22 zinc finger and BTB domain containing 22
ZNF23 zinc finger protein 23
ZNF268 zinc finger protein 268
ZNF282 zinc finger protein 282
ZNF37BP zinc finger protein 37B, pseudogene