reserpine-4203 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
Similar Terms
Downloads & Tools

Genes

197 genes differentially expressed following the reserpine-4203 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ACAA2 acetyl-CoA acyltransferase 2
ACVR1B activin A receptor, type IB
ADCY9 adenylate cyclase 9
AKAP8L A kinase (PRKA) anchor protein 8-like
ASPN asporin
ATG10 autophagy related 10
ATG16L1 autophagy related 16-like 1 (S. cerevisiae)
B9D1 B9 protein domain 1
BTNL3 butyrophilin-like 3
BTRC beta-transducin repeat containing E3 ubiquitin protein ligase
C17ORF59 chromosome 17 open reading frame 59
C17ORF70 chromosome 17 open reading frame 70
CD58 CD58 molecule
CDK10 cyclin-dependent kinase 10
CDKAL1 CDK5 regulatory subunit associated protein 1-like 1
CHRNA10 cholinergic receptor, nicotinic, alpha 10 (neuronal)
CLCN7 chloride channel, voltage-sensitive 7
CNOT4 CCR4-NOT transcription complex, subunit 4
DBNDD1 dysbindin (dystrobrevin binding protein 1) domain containing 1
DDX51 DEAD (Asp-Glu-Ala-Asp) box polypeptide 51
DIAPH2-AS1 DIAPH2 antisense RNA 1
DMBT1 deleted in malignant brain tumors 1
DNPH1 2'-deoxynucleoside 5'-phosphate N-hydrolase 1
DTNA dystrobrevin, alpha
ENPP2 ectonucleotide pyrophosphatase/phosphodiesterase 2
EPHA1 EPH receptor A1
FAM189A2 family with sequence similarity 189, member A2
FAM46C family with sequence similarity 46, member C
FLJ11292
FZD10 frizzled class receptor 10
GATM glycine amidinotransferase (L-arginine:glycine amidinotransferase)
GK3P glycerol kinase 3 pseudogene
GLB1L galactosidase, beta 1-like
GLUL glutamate-ammonia ligase
GNG7 guanine nucleotide binding protein (G protein), gamma 7
GP6 glycoprotein VI (platelet)
GPLD1 glycosylphosphatidylinositol specific phospholipase D1
HIST1H4H histone cluster 1, H4h
HLA-DMA major histocompatibility complex, class II, DM alpha
HSD17B8 hydroxysteroid (17-beta) dehydrogenase 8
HTR3A 5-hydroxytryptamine (serotonin) receptor 3A, ionotropic
ICOSLG inducible T-cell co-stimulator ligand
IL22 interleukin 22
INO80D INO80 complex subunit D
INPP4A inositol polyphosphate-4-phosphatase, type I, 107kDa
KCNJ5 potassium channel, inwardly rectifying subfamily J, member 5
KCNS1 potassium voltage-gated channel, modifier subfamily S, member 1
KIF13A kinesin family member 13A
L3MBTL1 l(3)mbt-like 1 (Drosophila)
LPL lipoprotein lipase
LRP1 low density lipoprotein receptor-related protein 1
LTB4R leukotriene B4 receptor
LTBP4 latent transforming growth factor beta binding protein 4
LYPD3 LY6/PLAUR domain containing 3
MORN1 MORN repeat containing 1
MST1 macrophage stimulating 1
MYL4 myosin, light chain 4, alkali; atrial, embryonic
N4BP2L2-IT2 N4BPL2 intronic transcript 2
NAAA N-acylethanolamine acid amidase
NFKBIL1 nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor-like 1
NOD1 nucleotide-binding oligomerization domain containing 1
NR1H3 nuclear receptor subfamily 1, group H, member 3
NR4A2 nuclear receptor subfamily 4, group A, member 2
PARP6 poly (ADP-ribose) polymerase family, member 6
PATZ1 POZ (BTB) and AT hook containing zinc finger 1
PDLIM3 PDZ and LIM domain 3
PDPR pyruvate dehydrogenase phosphatase regulatory subunit
PLCD1 phospholipase C, delta 1
PTN pleiotrophin
PTPRU protein tyrosine phosphatase, receptor type, U
PVR poliovirus receptor
RAB36 RAB36, member RAS oncogene family
RAB3D RAB3D, member RAS oncogene family
RB1 retinoblastoma 1
REC8 REC8 meiotic recombination protein
RFPL3S RFPL3 antisense
RHPN1-AS1 RHPN1 antisense RNA 1 (head to head)
RUNX1 runt-related transcription factor 1
SARM1 sterile alpha and TIR motif containing 1
SBNO1 strawberry notch homolog 1 (Drosophila)
SCARB1 scavenger receptor class B, member 1
SERPINB3 serpin peptidase inhibitor, clade B (ovalbumin), member 3
SMAD4 SMAD family member 4
SNX13 sorting nexin 13
SOS2 son of sevenless homolog 2 (Drosophila)
STC1 stanniocalcin 1
STK17B serine/threonine kinase 17b
SWAP70 SWAP switching B-cell complex 70kDa subunit
TAOK1 TAO kinase 1
TBRG4 transforming growth factor beta regulator 4
TFAP2C transcription factor AP-2 gamma (activating enhancer binding protein 2 gamma)
TNFSF15 tumor necrosis factor (ligand) superfamily, member 15
TNK2 tyrosine kinase, non-receptor, 2
TPP1 tripeptidyl peptidase I
TRA2A transformer 2 alpha homolog (Drosophila)
TSPAN8 tetraspanin 8
TTLL4 tubulin tyrosine ligase-like family member 4
WFDC2 WAP four-disulfide core domain 2
ZMIZ2 zinc finger, MIZ-type containing 2
ZNF639 zinc finger protein 639

decreased expression

Symbol Name
ACE angiotensin I converting enzyme
ACSBG2 acyl-CoA synthetase bubblegum family member 2
AGMAT agmatine ureohydrolase (agmatinase)
ANKRD2 ankyrin repeat domain 2 (stretch responsive muscle)
ARPIN actin-related protein 2/3 complex inhibitor
C22ORF46 chromosome 22 open reading frame 46
C7ORF69 chromosome 7 open reading frame 69
C8A complement component 8, alpha polypeptide
CAPN15 calpain 15
CASP5 caspase 5, apoptosis-related cysteine peptidase
CASS4 Cas scaffolding protein family member 4
CEMP1 cementum protein 1
CENPT centromere protein T
CLDN1 claudin 1
CLTCL1 clathrin, heavy chain-like 1
CNN1 calponin 1, basic, smooth muscle
CPA4 carboxypeptidase A4
CRYGC crystallin, gamma C
CXCL3 chemokine (C-X-C motif) ligand 3
DNAH17 dynein, axonemal, heavy chain 17
DSPP dentin sialophosphoprotein
DUSP8 dual specificity phosphatase 8
FAM53B family with sequence similarity 53, member B
FAM86C1 family with sequence similarity 86, member C1
FBRS fibrosin
FLT4 fms-related tyrosine kinase 4
FRMPD1 FERM and PDZ domain containing 1
GAS8 growth arrest-specific 8
GIT1 G protein-coupled receptor kinase interacting ArfGAP 1
GPR1 G protein-coupled receptor 1
GSTA3 glutathione S-transferase alpha 3
GTF2A1 general transcription factor IIA, 1, 19/37kDa
HIST1H1D histone cluster 1, H1d
HOOK1 hook microtubule-tethering protein 1
IBA57 IBA57, iron-sulfur cluster assembly homolog (S. cerevisiae)
IFI44L interferon-induced protein 44-like
IFT140 intraflagellar transport 140
IRF2BP1 interferon regulatory factor 2 binding protein 1
ITGB7 integrin, beta 7
KANSL3 KAT8 regulatory NSL complex subunit 3
KIAA1456 KIAA1456
KLF13 Kruppel-like factor 13
KRT20 keratin 20, type I
LOC202181 SUMO-interacting motifs containing 1 pseudogene
LRP3 low density lipoprotein receptor-related protein 3
LY6D lymphocyte antigen 6 complex, locus D
MAP6D1 MAP6 domain containing 1
MFGE8 milk fat globule-EGF factor 8 protein
MGP matrix Gla protein
MRPL41 mitochondrial ribosomal protein L41
MTCP1 mature T-cell proliferation 1
MTSS1L metastasis suppressor 1-like
MXRA8 matrix-remodelling associated 8
NACA2 nascent polypeptide-associated complex alpha subunit 2
NOTCH4 notch 4
NSD1 nuclear receptor binding SET domain protein 1
NTSR1 neurotensin receptor 1 (high affinity)
NUDT6 nudix (nucleoside diphosphate linked moiety X)-type motif 6
OR2F1 olfactory receptor, family 2, subfamily F, member 1 (gene/pseudogene)
PCDH12 protocadherin 12
PCDHGB5 protocadherin gamma subfamily B, 5
PDK4 pyruvate dehydrogenase kinase, isozyme 4
PITPNM1 phosphatidylinositol transfer protein, membrane-associated 1
PLAG1 pleiomorphic adenoma gene 1
PLBD1 phospholipase B domain containing 1
PLEKHF1 pleckstrin homology domain containing, family F (with FYVE domain) member 1
PPDPF pancreatic progenitor cell differentiation and proliferation factor
PROX1 prospero homeobox 1
RAPGEFL1 Rap guanine nucleotide exchange factor (GEF)-like 1
RAPSN receptor-associated protein of the synapse
RNF39 ring finger protein 39
RPP25 ribonuclease P/MRP 25kDa subunit
S1PR1 sphingosine-1-phosphate receptor 1
SCAMP5 secretory carrier membrane protein 5
SCARA3 scavenger receptor class A, member 3
SCIN scinderin
SLC2A8 solute carrier family 2 (facilitated glucose transporter), member 8
SLC9A2 solute carrier family 9, subfamily A (NHE2, cation proton antiporter 2), member 2
SOX21 SRY (sex determining region Y)-box 21
SPATA1 spermatogenesis associated 1
ST6GALNAC5 ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 5
STAG3 stromal antigen 3
TCTN2 tectonic family member 2
TESPA1 thymocyte expressed, positive selection associated 1
TMEM184C transmembrane protein 184C
TMEM212 transmembrane protein 212
TMPRSS4 transmembrane protease, serine 4
TNFRSF14 tumor necrosis factor receptor superfamily, member 14
TSPAN2 tetraspanin 2
TUT1 terminal uridylyl transferase 1, U6 snRNA-specific
VGF VGF nerve growth factor inducible
WNT1 wingless-type MMTV integration site family, member 1
ZNF358 zinc finger protein 358
ZNF391 zinc finger protein 391
ZNF428 zinc finger protein 428
ZNF747 zinc finger protein 747
ZNF749 zinc finger protein 749