response to insulin Gene Set

Dataset GO Biological Process Annotations 2025
Category structural or functional annotations
Type biological process
Description Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an insulin stimulus. Insulin is a polypeptide hormone produced by the islets of Langerhans of the pancreas in mammals, and by the homologous organs of other organisms. (Gene Ontology, GO_0032868)
External Link http://amigo.geneontology.org/amigo/term/GO:0032868
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Genes

83 genes participating in the response to insulin biological process from the curated GO Biological Process Annotations 2025 dataset.

Symbol Name
ADIPOQ adiponectin, C1Q and collagen domain containing
AKT1 v-akt murine thymoma viral oncogene homolog 1
AKT2 v-akt murine thymoma viral oncogene homolog 2
BGLAP bone gamma-carboxyglutamate (gla) protein
CAPN10 calpain 10
CEACAM1 carcinoembryonic antigen-related cell adhesion molecule 1 (biliary glycoprotein)
CELA2A chymotrypsin-like elastase family, member 2A
CITED1 Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 1
CPEB1 cytoplasmic polyadenylation element binding protein 1
CPEB2 cytoplasmic polyadenylation element binding protein 2
DENND4C DENN/MADD domain containing 4C
EIF6 eukaryotic translation initiation factor 6
ENPP1 ectonucleotide pyrophosphatase/phosphodiesterase 1
EPRS1 glutamyl-prolyl-tRNA synthetase 1
FOXO1 forkhead box O1
GHRHR growth hormone releasing hormone receptor
GOLT1A golgi transport 1A
GPLD1 glycosylphosphatidylinositol specific phospholipase D1
GRB10 growth factor receptor-bound protein 10
GSK3A glycogen synthase kinase 3 alpha
HDAC5 histone deacetylase 5
HDAC9 histone deacetylase 9
INHBB inhibin, beta B
INPP5K inositol polyphosphate-5-phosphatase K
INSIG1 insulin induced gene 1
INSIG2 insulin induced gene 2
INSR insulin receptor
IRS1 insulin receptor substrate 1
IRS2 insulin receptor substrate 2
KAT2B K(lysine) acetyltransferase 2B
KHK ketohexokinase (fructokinase)
LEP leptin
LPIN1 lipin 1
LPIN2 lipin 2
LPIN3 lipin 3
MAP4K2 mitogen-activated protein kinase kinase kinase kinase 2
MAPKAP1 mitogen-activated protein kinase associated protein 1
MEAK7 MTOR associated protein, eak-7 homolog
MTOR mechanistic target of rapamycin (serine/threonine kinase)
MYO5A myosin VA (heavy chain 12, myoxin)
OGT O-linked N-acetylglucosamine (GlcNAc) transferase
OTOP1 otopetrin 1
PARP1 poly (ADP-ribose) polymerase 1
PCK1 phosphoenolpyruvate carboxykinase 1 (soluble)
PCK2 phosphoenolpyruvate carboxykinase 2 (mitochondrial)
PCSK9 proprotein convertase subtilisin/kexin type 9
PDE3B phosphodiesterase 3B, cGMP-inhibited
PDPK1 3-phosphoinositide dependent protein kinase 1
PIK3CA phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit alpha
PIK3R1 phosphoinositide-3-kinase, regulatory subunit 1 (alpha)
PIK3R2 phosphoinositide-3-kinase, regulatory subunit 2 (beta)
PKLR pyruvate kinase, liver and RBC
PKM pyruvate kinase, muscle
PLA2G1B phospholipase A2, group IB (pancreas)
PPARG peroxisome proliferator-activated receptor gamma
PRKCI protein kinase C, iota
PRKCZ protein kinase C, zeta
PRKDC protein kinase, DNA-activated, catalytic polypeptide
RAB10 RAB10, member RAS oncogene family
RAB13 RAB13, member RAS oncogene family
RAB31 RAB31, member RAS oncogene family
RAB8A RAB8A, member RAS oncogene family
RHOQ ras homolog family member Q
RPS6KB1 ribosomal protein S6 kinase, 70kDa, polypeptide 1
SELENOS selenoprotein S
SIRT1 sirtuin 1
SLC25A33 solute carrier family 25 (pyrimidine nucleotide carrier), member 33
SLC2A1 solute carrier family 2 (facilitated glucose transporter), member 1
SLC2A4 solute carrier family 2 (facilitated glucose transporter), member 4
SLC39A14 solute carrier family 39 (zinc transporter), member 14
SORBS1 sorbin and SH3 domain containing 1
SORT1 sortilin 1
SYAP1 synapse associated protein 1
TBC1D4 TBC1 domain family, member 4
TRARG1 trafficking regulator of GLUT4 (SLC2A4) 1
TRIB3 tribbles pseudokinase 3
TSC1 tuberous sclerosis 1
USF1 upstream transcription factor 1
VAMP2 vesicle-associated membrane protein 2 (synaptobrevin 2)
XBP1 X-box binding protein 1
ZBED3 zinc finger, BED-type containing 3
ZBTB7B zinc finger and BTB domain containing 7B
ZFP36L1 ZFP36 ring finger protein-like 1