response to ionizing radiation Gene Set

Dataset GO Biological Process Annotations 2023
Category structural or functional annotations
Type biological process
Description Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a ionizing radiation stimulus. Ionizing radiation is radiation with sufficient energy to remove electrons from atoms and may arise from spontaneous decay of unstable isotopes, resulting in alpha and beta particles and gamma rays. Ionizing radiation also includes X-rays. (Gene Ontology, GO_0010212)
External Link http://amigo.geneontology.org/amigo/term/GO_0010212
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Genes

73 genes participating in the response to ionizing radiation biological process from the curated GO Biological Process Annotations 2023 dataset.

Symbol Name
ABRAXAS1 abraxas 1, BRCA1 A complex subunit
AEN apoptosis enhancing nuclease
ANXA1 annexin A1
ATM ATM serine/threonine kinase
BABAM1 BRISC and BRCA1 A complex member 1
BABAM2 BRISC and BRCA1 A complex member 2
BARD1 BRCA1 associated RING domain 1
BLM Bloom syndrome, RecQ helicase-like
BRAT1 BRCA1-associated ATM activator 1
BRCA1 breast cancer 1, early onset
BRCA2 breast cancer 2, early onset
BRSK1 BR serine/threonine kinase 1
CDKN1A cyclin-dependent kinase inhibitor 1A (p21, Cip1)
CLK2 CDC-like kinase 2
CLOCK clock circadian regulator
CNOT12 CCR4-NOT transcription complex subunit 12
COP1 COP1 E3 ubiquitin ligase
DCUN1D3 DCN1, defective in cullin neddylation 1, domain containing 3
DEPDC1B DEP domain containing 1B
ECT2 epithelial cell transforming 2
EEF1D eukaryotic translation elongation factor 1 delta (guanine nucleotide exchange protein)
ERCC4 excision repair cross-complementation group 4
EYA1 EYA transcriptional coactivator and phosphatase 1
EYA3 EYA transcriptional coactivator and phosphatase 3
FANCD2 Fanconi anemia, complementation group D2
FIGNL1 fidgetin-like 1
GADD45A growth arrest and DNA-damage-inducible, alpha
GRB2 growth factor receptor-bound protein 2
H2AX H2A.X variant histone
HUS1 HUS1 checkpoint homolog (S. pombe)
IFI16 interferon, gamma-inducible protein 16
IKBIP IKBKB interacting protein
INIP INTS3 and NABP interacting protein
INO80 INO80 complex subunit
INTS3 integrator complex subunit 3
INTS7 integrator complex subunit 7
KAT5 K(lysine) acetyltransferase 5
KDM4D lysine (K)-specific demethylase 4D
LIG4 ligase IV, DNA, ATP-dependent
MAPK14 mitogen-activated protein kinase 14
MEN1 multiple endocrine neoplasia I
MRNIP MRN complex interacting protein
MSH2 mutS homolog 2
MTA1 metastasis associated 1
MYC v-myc avian myelocytomatosis viral oncogene homolog
NABP1 nucleic acid binding protein 1
NABP2 nucleic acid binding protein 2
NHEJ1 nonhomologous end-joining factor 1
PAXIP1 PAX interacting (with transcription-activation domain) protein 1
PRKAA1 protein kinase, AMP-activated, alpha 1 catalytic subunit
RAD51 RAD51 recombinase
RAD51AP1 RAD51 associated protein 1
RAD9A RAD9 homolog A (S. pombe)
RAD9B RAD9 homolog B (S. pombe)
RFWD3 ring finger and WD repeat domain 3
RHNO1 RAD9-HUS1-RAD1 interacting nuclear orphan 1
RHOB ras homolog family member B
RNF168 ring finger protein 168, E3 ubiquitin protein ligase
RNF8 ring finger protein 8, E3 ubiquitin protein ligase
SIRT1 sirtuin 1
SLC6A2 solute carrier family 6 (neurotransmitter transporter), member 2
SMPD1 sphingomyelin phosphodiesterase 1, acid lysosomal
SPIDR scaffolding protein involved in DNA repair
STK11 serine/threonine kinase 11
SWI5 SWI5 recombination repair homolog (yeast)
TANK TRAF family member-associated NFKB activator
TICRR TOPBP1-interacting checkpoint and replication regulator
TOPBP1 topoisomerase (DNA) II binding protein 1
TP53 tumor protein p53
UIMC1 ubiquitin interaction motif containing 1
USP28 ubiquitin specific peptidase 28
XRCC4 X-ray repair complementing defective repair in Chinese hamster cells 4
XRRA1 X-ray radiation resistance associated 1