response to methotrexate Gene Set

Dataset GO Biological Process Annotations 2015
Category structural or functional annotations
Type biological process
Description Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a methotrexate stimulus. Methotrexate is 4-amino-10-methylformic acid, a folic acid analogue that is a potent competitive inhibitor of dihydrofolate reductase. (Gene Ontology, GO_0031427)
External Link http://amigo.geneontology.org/amigo/term/GO:0031427
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Genes

5 genes participating in the response to methotrexate biological process from the curated GO Biological Process Annotations 2015 dataset.

Symbol Name
ABCC2 ATP-binding cassette, sub-family C (CFTR/MRP), member 2
ASNS asparagine synthetase (glutamine-hydrolyzing)
DHFR dihydrofolate reductase
SLC22A6 solute carrier family 22 (organic anion transporter), member 6
SLC22A8 solute carrier family 22 (organic anion transporter), member 8