responsiveness Gene Set

Dataset GeneRIF Biological Term Annotations
Category structural or functional annotations
Type biological term
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Genes

395 genes co-occuring with the biological term responsiveness in literature-supported statements describing functions of genes from the GeneRIF Biological Term Annotations dataset.

Symbol Name
A2M alpha-2-macroglobulin
ABCA1 ATP-binding cassette, sub-family A (ABC1), member 1
ABCB1 ATP-binding cassette, sub-family B (MDR/TAP), member 1
ABCC2 ATP-binding cassette, sub-family C (CFTR/MRP), member 2
ABCG5 ATP-binding cassette, sub-family G (WHITE), member 5
ABCG8 ATP-binding cassette, sub-family G (WHITE), member 8
ABL1 ABL proto-oncogene 1, non-receptor tyrosine kinase
ABRA actin binding Rho activating protein
ACE angiotensin I converting enzyme
ACO1 aconitase 1, soluble
ACSL5 acyl-CoA synthetase long-chain family member 5
ACTN3 actinin, alpha 3 (gene/pseudogene)
ADAMTS13 ADAM metallopeptidase with thrombospondin type 1 motif, 13
ADORA2A adenosine A2a receptor
ADORA2B adenosine A2b receptor
ADRA2B adrenoceptor alpha 2B
ADRB1 adrenoceptor beta 1
ADRB2 adrenoceptor beta 2, surface
ADRBK1 adrenergic, beta, receptor kinase 1
AGT angiotensinogen (serpin peptidase inhibitor, clade A, member 8)
AGTR1 angiotensin II receptor, type 1
AGXT alanine-glyoxylate aminotransferase
AKT1 v-akt murine thymoma viral oncogene homolog 1
ALK anaplastic lymphoma receptor tyrosine kinase
ALOX5AP arachidonate 5-lipoxygenase-activating protein
AMOT angiomotin
ANKRD11 ankyrin repeat domain 11
ANXA5 annexin A5
APAF1 apoptotic peptidase activating factor 1
APEX1 APEX nuclease (multifunctional DNA repair enzyme) 1
AQP1 aquaporin 1 (Colton blood group)
AR androgen receptor
ARRB2 arrestin, beta 2
ATP13A2 ATPase type 13A2
ATP5J ATP synthase, H+ transporting, mitochondrial Fo complex, subunit F6
BAG3 BCL2-associated athanogene 3
BAX BCL2-associated X protein
BCL2 B-cell CLL/lymphoma 2
BCL2L1 BCL2-like 1
BCO1 beta-carotene oxygenase 1
BMP2 bone morphogenetic protein 2
BMP4 bone morphogenetic protein 4
BRAF B-Raf proto-oncogene, serine/threonine kinase
BTNL2 butyrophilin-like 2
C4B complement component 4B (Chido blood group)
CA9 carbonic anhydrase IX
CALCA calcitonin-related polypeptide alpha
CASR calcium-sensing receptor
CCL20 chemokine (C-C motif) ligand 20
CCL22 chemokine (C-C motif) ligand 22
CCR1 chemokine (C-C motif) receptor 1
CCR2 chemokine (C-C motif) receptor 2
CCR5 chemokine (C-C motif) receptor 5 (gene/pseudogene)
CCR6 chemokine (C-C motif) receptor 6
CD160 CD160 molecule
CD1D CD1d molecule
CD274 CD274 molecule
CD4 CD4 molecule
CD40 CD40 molecule, TNF receptor superfamily member 5
CD5 CD5 molecule
CDKN2A cyclin-dependent kinase inhibitor 2A
CDKN2B cyclin-dependent kinase inhibitor 2B (p15, inhibits CDK4)
CEACAM5 carcinoembryonic antigen-related cell adhesion molecule 5
CEBPB CCAAT/enhancer binding protein (C/EBP), beta
CES1 carboxylesterase 1
CES2 carboxylesterase 2
CETP cholesteryl ester transfer protein, plasma
CFTR cystic fibrosis transmembrane conductance regulator (ATP-binding cassette sub-family C, member 7)
CHRM4 cholinergic receptor, muscarinic 4
CHRNA4 cholinergic receptor, nicotinic, alpha 4 (neuronal)
CHRNB2 cholinergic receptor, nicotinic, beta 2 (neuronal)
CKS1BP7 CDC28 protein kinase regulatory subunit 1B pseudogene 7
CNTN2 contactin 2 (axonal)
COMT catechol-O-methyltransferase
CREB1 cAMP responsive element binding protein 1
CRHR1 corticotropin releasing hormone receptor 1
CRP C-reactive protein, pentraxin-related
CSF1 colony stimulating factor 1 (macrophage)
CSF2 colony stimulating factor 2 (granulocyte-macrophage)
CTLA4 cytotoxic T-lymphocyte-associated protein 4
CTSG cathepsin G
CXCL10 chemokine (C-X-C motif) ligand 10
CXCL12 chemokine (C-X-C motif) ligand 12
CXCR3 chemokine (C-X-C motif) receptor 3
CXCR4 chemokine (C-X-C motif) receptor 4
CYP17A1 cytochrome P450, family 17, subfamily A, polypeptide 1
CYP1A2 cytochrome P450, family 1, subfamily A, polypeptide 2
CYP24A1 cytochrome P450, family 24, subfamily A, polypeptide 1
CYP2C19 cytochrome P450, family 2, subfamily C, polypeptide 19
CYP2D6 cytochrome P450, family 2, subfamily D, polypeptide 6
CYP3A4 cytochrome P450, family 3, subfamily A, polypeptide 4
DEFB1 defensin, beta 1
DIO3 deiodinase, iodothyronine, type III
DPP3 dipeptidyl-peptidase 3
DRD1 dopamine receptor D1
DRD5 dopamine receptor D5
DSP desmoplakin
EDN1 endothelin 1
EGF epidermal growth factor
EGFR epidermal growth factor receptor
EI24 etoposide induced 2.4
EIF3I eukaryotic translation initiation factor 3, subunit I
ELANE elastase, neutrophil expressed
ELK1 ELK1, member of ETS oncogene family
EPHA2 EPH receptor A2
EPO erythropoietin
EPS8 epidermal growth factor receptor pathway substrate 8
ERBB2 erb-b2 receptor tyrosine kinase 2
ERBB3 erb-b2 receptor tyrosine kinase 3
ERBB4 erb-b2 receptor tyrosine kinase 4
ESR1 estrogen receptor 1
ESR2 estrogen receptor 2 (ER beta)
ETS1 v-ets avian erythroblastosis virus E26 oncogene homolog 1
F2R coagulation factor II (thrombin) receptor
F2RL3 coagulation factor II (thrombin) receptor-like 3
FAAH fatty acid amide hydrolase
FAS Fas cell surface death receptor
FASLG Fas ligand (TNF superfamily, member 6)
FBXO7 F-box protein 7
FBXW7 F-box and WD repeat domain containing 7, E3 ubiquitin protein ligase
FKBP5 FK506 binding protein 5
FOS FBJ murine osteosarcoma viral oncogene homolog
FSHR follicle stimulating hormone receptor
FTO fat mass and obesity associated
GCG glucagon
GCK glucokinase (hexokinase 4)
GDNF glial cell derived neurotrophic factor
GFRA1 GDNF family receptor alpha 1
GH1 growth hormone 1
GHR growth hormone receptor
GHRH growth hormone releasing hormone
GHRL ghrelin/obestatin prepropeptide
GIP gastric inhibitory polypeptide
GLP1R glucagon-like peptide 1 receptor
GP6 glycoprotein VI (platelet)
GPBAR1 G protein-coupled bile acid receptor 1
GRIN1 glutamate receptor, ionotropic, N-methyl D-aspartate 1
GRK6 G protein-coupled receptor kinase 6
GSTK1 glutathione S-transferase kappa 1
GSTT1 glutathione S-transferase theta 1
GULP1 GULP, engulfment adaptor PTB domain containing 1
GYPA glycophorin A (MNS blood group)
HBEGF heparin-binding EGF-like growth factor
HDAC2 histone deacetylase 2
HDAC6 histone deacetylase 6
HES1 hes family bHLH transcription factor 1
HGF hepatocyte growth factor (hepapoietin A; scatter factor)
HIF1A hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor)
HLA-A major histocompatibility complex, class I, A
HLA-B major histocompatibility complex, class I, B
HLA-DPB1 major histocompatibility complex, class II, DP beta 1
HLA-DQB1 major histocompatibility complex, class II, DQ beta 1
HMOX1 heme oxygenase 1
HRH1 histamine receptor H1
HSD11B1 hydroxysteroid (11-beta) dehydrogenase 1
HSPA5 heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa)
HTR3A 5-hydroxytryptamine (serotonin) receptor 3A, ionotropic
HTRA1 HtrA serine peptidase 1
IFN1@ interferon, type 1, cluster
IFNAR2 interferon (alpha, beta and omega) receptor 2
IFNG interferon, gamma
IFNGR1 interferon gamma receptor 1
IFNL1 interferon, lambda 1
IFNL3 interferon, lambda 3
IGF1 insulin-like growth factor 1 (somatomedin C)
IGFBP1 insulin-like growth factor binding protein 1
IGFBP3 insulin-like growth factor binding protein 3
IKBKE inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase epsilon
IL10 interleukin 10
IL13 interleukin 13
IL13RA2 interleukin 13 receptor, alpha 2
IL15 interleukin 15
IL17A interleukin 17A
IL18 interleukin 18
IL1B interleukin 1, beta
IL1R2 interleukin 1 receptor, type II
IL2 interleukin 2
IL27 interleukin 27
IL2RA interleukin 2 receptor, alpha
IL2RB interleukin 2 receptor, beta
IL34 interleukin 34
IL4 interleukin 4
IL4R interleukin 4 receptor
IL5 interleukin 5
IL6 interleukin 6
IL6R interleukin 6 receptor
IL7 interleukin 7
IL7R interleukin 7 receptor
INPP5F inositol polyphosphate-5-phosphatase F
INS insulin
INSR insulin receptor
IRF1 interferon regulatory factor 1
IRF5 interferon regulatory factor 5
ITGAL integrin, alpha L (antigen CD11A (p180), lymphocyte function-associated antigen 1; alpha polypeptide)
JAK2 Janus kinase 2
JUN jun proto-oncogene
KCNA1 potassium channel, voltage gated shaker related subfamily A, member 1
KCNA3 potassium channel, voltage gated shaker related subfamily A, member 3
KCNMA1 potassium channel, calcium activated large conductance subfamily M alpha, member 1
KIF21A kinesin family member 21A
KISS1R KISS1 receptor
KLRK1 killer cell lectin-like receptor subfamily K, member 1
KRAS Kirsten rat sarcoma viral oncogene homolog
KRT19 keratin 19, type I
LCN2 lipocalin 2
LHCGR luteinizing hormone/choriogonadotropin receptor
LTA4H leukotriene A4 hydrolase
LTBR lymphotoxin beta receptor (TNFR superfamily, member 3)
LTC4S leukotriene C4 synthase
LY96 lymphocyte antigen 96
MAPK1 mitogen-activated protein kinase 1
MAPK3 mitogen-activated protein kinase 3
MAPK8IP1 mitogen-activated protein kinase 8 interacting protein 1
MAPT microtubule-associated protein tau
MARCKS myristoylated alanine-rich protein kinase C substrate
MC1R melanocortin 1 receptor (alpha melanocyte stimulating hormone receptor)
MC4R melanocortin 4 receptor
MCL1 myeloid cell leukemia 1
MEFV Mediterranean fever
MICA MHC class I polypeptide-related sequence A
MICB MHC class I polypeptide-related sequence B
MIR223 microRNA 223
MMP2 matrix metallopeptidase 2
MST1R macrophage stimulating 1 receptor
MTHFR methylenetetrahydrofolate reductase (NAD(P)H)
MTOR mechanistic target of rapamycin (serine/threonine kinase)
MYC v-myc avian myelocytomatosis viral oncogene homolog
NCF1C neutrophil cytosolic factor 1C pseudogene
NCOA3 nuclear receptor coactivator 3
NDST1 N-deacetylase/N-sulfotransferase (heparan glucosaminyl) 1
NFATC1 nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 1
NFATC2 nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 2
NFE2L2 nuclear factor, erythroid 2-like 2
NFKB1 nuclear factor of kappa light polypeptide gene enhancer in B-cells 1
NFYB nuclear transcription factor Y, beta
NKX2-5 NK2 homeobox 5
NME1 NME/NM23 nucleoside diphosphate kinase 1
NOD2 nucleotide-binding oligomerization domain containing 2
NOS1 nitric oxide synthase 1 (neuronal)
NOS3 nitric oxide synthase 3 (endothelial cell)
NOTCH1 notch 1
NPM1 nucleophosmin (nucleolar phosphoprotein B23, numatrin)
NPR1 natriuretic peptide receptor 1
NPSR1 neuropeptide S receptor 1
NQO1 NAD(P)H dehydrogenase, quinone 1
NR1H2 nuclear receptor subfamily 1, group H, member 2
NR3C1 nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor)
NR3C2 nuclear receptor subfamily 3, group C, member 2
NUP214 nucleoporin 214kDa
OR1A1 olfactory receptor, family 1, subfamily A, member 1
OR1A2 olfactory receptor, family 1, subfamily A, member 2
OXT oxytocin/neurophysin I prepropeptide
OXTR oxytocin receptor
P2RX1 purinergic receptor P2X, ligand gated ion channel, 1
P2RY12 purinergic receptor P2Y, G-protein coupled, 12
PARK2 parkin RBR E3 ubiquitin protein ligase
PARP1 poly (ADP-ribose) polymerase 1
PCNA proliferating cell nuclear antigen
PDCD1 programmed cell death 1
PDGFRA platelet-derived growth factor receptor, alpha polypeptide
PDGFRB platelet-derived growth factor receptor, beta polypeptide
PDLIM7 PDZ and LIM domain 7 (enigma)
PDZD2 PDZ domain containing 2
PGR progesterone receptor
PIGR polymeric immunoglobulin receptor
PIK3CG phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit gamma
PINK1 PTEN induced putative kinase 1
PLA2G6 phospholipase A2, group VI (cytosolic, calcium-independent)
PLAC1 placenta-specific 1
PLCE1 phospholipase C, epsilon 1
PNPO pyridoxamine 5'-phosphate oxidase
POLR2M polymerase (RNA) II (DNA directed) polypeptide M
POMC proopiomelanocortin
PON1 paraoxonase 1
POU1F1 POU class 1 homeobox 1
PPARA peroxisome proliferator-activated receptor alpha
PPARG peroxisome proliferator-activated receptor gamma
PRDM16 PR domain containing 16
PRDX2 peroxiredoxin 2
PRKCD protein kinase C, delta
PRL prolactin
PRLR prolactin receptor
PTEN phosphatase and tensin homolog
PTGDR prostaglandin D2 receptor (DP)
PTGER2 prostaglandin E receptor 2 (subtype EP2), 53kDa
PTK2B protein tyrosine kinase 2 beta
PTPN11 protein tyrosine phosphatase, non-receptor type 11
PTPN2 protein tyrosine phosphatase, non-receptor type 2
PTPN6 protein tyrosine phosphatase, non-receptor type 6
RAC1 ras-related C3 botulinum toxin substrate 1 (rho family, small GTP binding protein Rac1)
RARRES1 retinoic acid receptor responder (tazarotene induced) 1
RASD1 RAS, dexamethasone-induced 1
RBP2 retinol binding protein 2, cellular
RBPJ recombination signal binding protein for immunoglobulin kappa J region
RETN resistin
RGS4 regulator of G-protein signaling 4
RGS7BP regulator of G-protein signaling 7 binding protein
RIPK3 receptor-interacting serine-threonine kinase 3
RNF11 ring finger protein 11
ROBO3 roundabout, axon guidance receptor, homolog 3 (Drosophila)
ROBO4 roundabout, axon guidance receptor, homolog 4 (Drosophila)
ROR2 receptor tyrosine kinase-like orphan receptor 2
RPS6KA1 ribosomal protein S6 kinase, 90kDa, polypeptide 1
RUNX1 runt-related transcription factor 1
RUNX2 runt-related transcription factor 2
RXRA retinoid X receptor, alpha
RXRB retinoid X receptor, beta
S100A9 S100 calcium binding protein A9
S1PR1 sphingosine-1-phosphate receptor 1
SCGB1A1 secretoglobin, family 1A, member 1 (uteroglobin)
SCN1A sodium channel, voltage gated, type I alpha subunit
SCN2A sodium channel, voltage gated, type II alpha subunit
SCN3A sodium channel, voltage gated, type III alpha subunit
SDC2 syndecan 2
SDC4 syndecan 4
SET SET nuclear proto-oncogene
SHH sonic hedgehog
SIGLEC9 sialic acid binding Ig-like lectin 9
SIRT1 sirtuin 1
SKI SKI proto-oncogene
SKP2 S-phase kinase-associated protein 2, E3 ubiquitin protein ligase
SLAMF1 signaling lymphocytic activation molecule family member 1
SLC16A2 solute carrier family 16, member 2 (thyroid hormone transporter)
SLC2A4 solute carrier family 2 (facilitated glucose transporter), member 4
SLC4A1 solute carrier family 4 (anion exchanger), member 1 (Diego blood group)
SLC6A3 solute carrier family 6 (neurotransmitter transporter), member 3
SLC6A4 solute carrier family 6 (neurotransmitter transporter), member 4
SMAD3 SMAD family member 3
SMAD4 SMAD family member 4
SMARCA2 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 2
SMARCA4 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 4
SMURF1 SMAD specific E3 ubiquitin protein ligase 1
SMURF2 SMAD specific E3 ubiquitin protein ligase 2
SOCS1 suppressor of cytokine signaling 1
SOCS3 suppressor of cytokine signaling 3
SOD1 superoxide dismutase 1, soluble
SP1 Sp1 transcription factor
SPP1 secreted phosphoprotein 1
SRSF3 serine/arginine-rich splicing factor 3
SRSF5 serine/arginine-rich splicing factor 5
SRSF9 serine/arginine-rich splicing factor 9
SSTR2 somatostatin receptor 2
SSTR5 somatostatin receptor 5
STAT1 signal transducer and activator of transcription 1, 91kDa
STAT3 signal transducer and activator of transcription 3 (acute-phase response factor)
STAT6 signal transducer and activator of transcription 6, interleukin-4 induced
STK17B serine/threonine kinase 17b
SULT2B1 sulfotransferase family, cytosolic, 2B, member 1
TBK1 TANK-binding kinase 1
TBX21 T-box 21
TERT telomerase reverse transcriptase
TFAP2C transcription factor AP-2 gamma (activating enhancer binding protein 2 gamma)
TG thyroglobulin
TGFB1 transforming growth factor, beta 1
TGFBR1 transforming growth factor, beta receptor 1
TGM2 transglutaminase 2
THRB thyroid hormone receptor, beta
TLR1 toll-like receptor 1
TLR2 toll-like receptor 2
TLR3 toll-like receptor 3
TLR4 toll-like receptor 4
TLR5 toll-like receptor 5
TLR6 toll-like receptor 6
TLR7 toll-like receptor 7
TLR8 toll-like receptor 8
TLR9 toll-like receptor 9
TNC tenascin C
TNF tumor necrosis factor
TNFRSF13C tumor necrosis factor receptor superfamily, member 13C
TNFRSF1A tumor necrosis factor receptor superfamily, member 1A
TNFRSF1B tumor necrosis factor receptor superfamily, member 1B
TNFSF11 tumor necrosis factor (ligand) superfamily, member 11
TOP2A topoisomerase (DNA) II alpha 170kDa
TP53 tumor protein p53
TP63 tumor protein p63
TP73 tumor protein p73
TPH2 tryptophan hydroxylase 2
TREM1 triggering receptor expressed on myeloid cells 1
TRIM22 tripartite motif containing 22
TRPC3 transient receptor potential cation channel, subfamily C, member 3
TRPC6 transient receptor potential cation channel, subfamily C, member 6
TRPM2 transient receptor potential cation channel, subfamily M, member 2
UBE2I ubiquitin-conjugating enzyme E2I
UNC93B1 unc-93 homolog B1 (C. elegans)
VASP vasodilator-stimulated phosphoprotein
VDR vitamin D (1,25- dihydroxyvitamin D3) receptor
VEGFA vascular endothelial growth factor A
VEGFC vascular endothelial growth factor C
VKORC1 vitamin K epoxide reductase complex, subunit 1
VSNL1 visinin-like 1
WNT3A wingless-type MMTV integration site family, member 3A
XBP1 X-box binding protein 1
XIAP X-linked inhibitor of apoptosis, E3 ubiquitin protein ligase
YWHAE tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, epsilon
ZNF217 zinc finger protein 217