restricted Gene Set

Dataset GeneRIF Biological Term Annotations
Category structural or functional annotations
Type biological term
Similar Terms
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Genes

442 genes co-occuring with the biological term restricted in literature-supported statements describing functions of genes from the GeneRIF Biological Term Annotations dataset.

Symbol Name
ACHE acetylcholinesterase (Yt blood group)
ACPP acid phosphatase, prostate
ACTA2 actin, alpha 2, smooth muscle, aorta
ACVR2A activin A receptor, type IIA
ADAM10 ADAM metallopeptidase domain 10
ADAM12 ADAM metallopeptidase domain 12
ADAM9 ADAM metallopeptidase domain 9
ADAMTS4 ADAM metallopeptidase with thrombospondin type 1 motif, 4
ADAMTS5 ADAM metallopeptidase with thrombospondin type 1 motif, 5
ADGRE5 adhesion G protein-coupled receptor E5
AGER advanced glycosylation end product-specific receptor
AGO2 argonaute RISC catalytic component 2
AHR aryl hydrocarbon receptor
AIRE autoimmune regulator
ALCAM activated leukocyte cell adhesion molecule
ALDH1A1 aldehyde dehydrogenase 1 family, member A1
ALK anaplastic lymphoma receptor tyrosine kinase
APOA5 apolipoprotein A-V
APOBEC3C apolipoprotein B mRNA editing enzyme, catalytic polypeptide-like 3C
APOE apolipoprotein E
APP amyloid beta (A4) precursor protein
APPL1 adaptor protein, phosphotyrosine interaction, PH domain and leucine zipper containing 1
AQP4 aquaporin 4
ARHGDIB Rho GDP dissociation inhibitor (GDI) beta
ARHGEF18 Rho/Rac guanine nucleotide exchange factor (GEF) 18
ARHGEF4 Rho guanine nucleotide exchange factor (GEF) 4
ARL2BP ADP-ribosylation factor-like 2 binding protein
ASCL1 achaete-scute family bHLH transcription factor 1
ASPM asp (abnormal spindle) homolog, microcephaly associated (Drosophila)
ATF3 activating transcription factor 3
ATM ATM serine/threonine kinase
ATP7A ATPase, Cu++ transporting, alpha polypeptide
ATR ATR serine/threonine kinase
AURKA aurora kinase A
AURKB aurora kinase B
AXL AXL receptor tyrosine kinase
AZIN2 antizyme inhibitor 2
BAX BCL2-associated X protein
BCAR4 breast cancer anti-estrogen resistance 4 (non-protein coding)
BCAT1 branched chain amino-acid transaminase 1, cytosolic
BCAT2 branched chain amino-acid transaminase 2, mitochondrial
BCL2 B-cell CLL/lymphoma 2
BCL2A1 BCL2-related protein A1
BCL3 B-cell CLL/lymphoma 3
BCR breakpoint cluster region
BDNF brain-derived neurotrophic factor
BIRC5 baculoviral IAP repeat containing 5
BLK BLK proto-oncogene, Src family tyrosine kinase
BMP7 bone morphogenetic protein 7
BMPR1A bone morphogenetic protein receptor, type IA
BRAF B-Raf proto-oncogene, serine/threonine kinase
BRCA2 breast cancer 2, early onset
BST2 bone marrow stromal cell antigen 2
C6ORF25 chromosome 6 open reading frame 25
CALB2 calbindin 2
CALCA calcitonin-related polypeptide alpha
CALR calreticulin
CAMK2A calcium/calmodulin-dependent protein kinase II alpha
CASP3 caspase 3, apoptosis-related cysteine peptidase
CCL13 chemokine (C-C motif) ligand 13
CCNA2 cyclin A2
CCNB3 cyclin B3
CCR1 chemokine (C-C motif) receptor 1
CD163 CD163 molecule
CD19 CD19 molecule
CD28 CD28 molecule
CD300E CD300e molecule
CD300LB CD300 molecule-like family member b
CD300LD CD300 molecule-like family member d
CD300LF CD300 molecule-like family member f
CD4 CD4 molecule
CD44 CD44 molecule (Indian blood group)
CD46 CD46 molecule, complement regulatory protein
CD6 CD6 molecule
CD69 CD69 molecule
CD8A CD8a molecule
CDH1 cadherin 1, type 1, E-cadherin (epithelial)
CDK1 cyclin-dependent kinase 1
CDKN1A cyclin-dependent kinase inhibitor 1A (p21, Cip1)
CDKN2A cyclin-dependent kinase inhibitor 2A
CENPA centromere protein A
CENPT centromere protein T
CFH complement factor H
CHRDL2 chordin-like 2
CHRNA2 cholinergic receptor, nicotinic, alpha 2 (neuronal)
CLEC4M C-type lectin domain family 4, member M
CNR1 cannabinoid receptor 1 (brain)
CNR2 cannabinoid receptor 2 (macrophage)
COL4A1 collagen, type IV, alpha 1
COL4A3 collagen, type IV, alpha 3 (Goodpasture antigen)
COL4A5 collagen, type IV, alpha 5
COL4A6 collagen, type IV, alpha 6
COL5A1 collagen, type V, alpha 1
COL6A5 collagen, type VI, alpha 5
COL6A6 collagen, type VI, alpha 6
COMT catechol-O-methyltransferase
CRYGD crystallin, gamma D
CSF2 colony stimulating factor 2 (granulocyte-macrophage)
CTCF CCCTC-binding factor (zinc finger protein)
CTNNB1 catenin (cadherin-associated protein), beta 1, 88kDa
CTSG cathepsin G
CTSK cathepsin K
CTSZ cathepsin Z
CTXN3 cortexin 3
CXCR2 chemokine (C-X-C motif) receptor 2
CYBB cytochrome b-245, beta polypeptide
CYP17A1 cytochrome P450, family 17, subfamily A, polypeptide 1
CYP1B1 cytochrome P450, family 1, subfamily B, polypeptide 1
CYP21A2 cytochrome P450, family 21, subfamily A, polypeptide 2
CYP26A1 cytochrome P450, family 26, subfamily A, polypeptide 1
CYP27B1 cytochrome P450, family 27, subfamily B, polypeptide 1
CYP2C9 cytochrome P450, family 2, subfamily C, polypeptide 9
CYP2D6 cytochrome P450, family 2, subfamily D, polypeptide 6
CYP3A4 cytochrome P450, family 3, subfamily A, polypeptide 4
DAAM1 dishevelled associated activator of morphogenesis 1
DAZ1 deleted in azoospermia 1
DEFB126 defensin, beta 126
DNM1 dynamin 1
DNMT1 DNA (cytosine-5-)-methyltransferase 1
DNMT3B DNA (cytosine-5-)-methyltransferase 3 beta
DPP4 dipeptidyl-peptidase 4
DPPA2 developmental pluripotency associated 2
DSG1 desmoglein 1
DYRK1B dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1B
DYRK4 dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 4
EBI3 Epstein-Barr virus induced 3
EEF1A2 eukaryotic translation elongation factor 1 alpha 2
EGFL7 EGF-like-domain, multiple 7
EGFR epidermal growth factor receptor
EGR1 early growth response 1
ELF5 E74-like factor 5 (ets domain transcription factor)
ENTPD1 ectonucleoside triphosphate diphosphohydrolase 1
EPHA2 EPH receptor A2
ERBB2 erb-b2 receptor tyrosine kinase 2
ESPL1 extra spindle pole bodies homolog 1 (S. cerevisiae)
F2 coagulation factor II (thrombin)
F8 coagulation factor VIII, procoagulant component
FAP fibroblast activation protein, alpha
FAS Fas cell surface death receptor
FCRL4 Fc receptor-like 4
FDCSP follicular dendritic cell secreted protein
FGA fibrinogen alpha chain
FGB fibrinogen beta chain
FGG fibrinogen gamma chain
FLG filaggrin
FLT4 fms-related tyrosine kinase 4
FMO1 flavin containing monooxygenase 1
FOLR1 folate receptor 1 (adult)
FOXM1 forkhead box M1
FOXP3 forkhead box P3
FRMD7 FERM domain containing 7
FTO fat mass and obesity associated
FYN FYN proto-oncogene, Src family tyrosine kinase
GAPDHS glyceraldehyde-3-phosphate dehydrogenase, spermatogenic
GART phosphoribosylglycinamide formyltransferase, phosphoribosylglycinamide synthetase, phosphoribosylaminoimidazole synthetase
GATA1 GATA binding protein 1 (globin transcription factor 1)
GATA3 GATA binding protein 3
GCSAM germinal center-associated, signaling and motility
GDF5 growth differentiation factor 5
GFRA1 GDNF family receptor alpha 1
GHRL ghrelin/obestatin prepropeptide
GLI3 GLI family zinc finger 3
GLP1R glucagon-like peptide 1 receptor
GNAS GNAS complex locus
GSTM1 glutathione S-transferase mu 1
GZMB granzyme B (granzyme 2, cytotoxic T-lymphocyte-associated serine esterase 1)
HAVCR1 hepatitis A virus cellular receptor 1
HAVCR2 hepatitis A virus cellular receptor 2
HBB hemoglobin, beta
HCAR1 hydroxycarboxylic acid receptor 1
HDC histidine decarboxylase
HIST4H4 histone cluster 4, H4
HLA-A major histocompatibility complex, class I, A
HLA-B major histocompatibility complex, class I, B
HLA-DPB1 major histocompatibility complex, class II, DP beta 1
HLA-DQB1 major histocompatibility complex, class II, DQ beta 1
HLA-DRB1 major histocompatibility complex, class II, DR beta 1
HLA-DRB4 major histocompatibility complex, class II, DR beta 4
HMGA1 high mobility group AT-hook 1
HMHA1 histocompatibility (minor) HA-1
HNF1B HNF1 homeobox B
HNRNPD heterogeneous nuclear ribonucleoprotein D (AU-rich element RNA binding protein 1, 37kDa)
HOXA10 homeobox A10
HPS5 Hermansky-Pudlak syndrome 5
HRAS Harvey rat sarcoma viral oncogene homolog
HTR1D 5-hydroxytryptamine (serotonin) receptor 1D, G protein-coupled
HTR2A 5-hydroxytryptamine (serotonin) receptor 2A, G protein-coupled
IDH1 isocitrate dehydrogenase 1 (NADP+), soluble
IDH2 isocitrate dehydrogenase 2 (NADP+), mitochondrial
IFNA1 interferon, alpha 1
IFNG interferon, gamma
IFNL1 interferon, lambda 1
IGF1 insulin-like growth factor 1 (somatomedin C)
IGF2 insulin-like growth factor 2
IGF2BP3 insulin-like growth factor 2 mRNA binding protein 3
IHH indian hedgehog
IKBKB inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase beta
IKZF1 IKAROS family zinc finger 1 (Ikaros)
IL10 interleukin 10
IL17F interleukin 17F
IL17RB interleukin 17 receptor B
IL1B interleukin 1, beta
IL21 interleukin 21
IL22 interleukin 22
IL22RA1 interleukin 22 receptor, alpha 1
IL27 interleukin 27
IL2RA interleukin 2 receptor, alpha
IL2RG interleukin 2 receptor, gamma
IL4 interleukin 4
IL6 interleukin 6
ITGA2B integrin, alpha 2b (platelet glycoprotein IIb of IIb/IIIa complex, antigen CD41)
ITGB2 integrin, beta 2 (complement component 3 receptor 3 and 4 subunit)
ITGB3 integrin, beta 3 (platelet glycoprotein IIIa, antigen CD61)
ITGB4 integrin, beta 4
JAG1 jagged 1
JAK2 Janus kinase 2
JAK3 Janus kinase 3
KCNH2 potassium channel, voltage gated eag related subfamily H, member 2
KCNJ5 potassium channel, inwardly rectifying subfamily J, member 5
KCNMB1 potassium channel subfamily M regulatory beta subunit 1
KCNQ1OT1 KCNQ1 opposite strand/antisense transcript 1 (non-protein coding)
KIF21A kinesin family member 21A
KIF4A kinesin family member 4A
KIR2DL3 killer cell immunoglobulin-like receptor, two domains, long cytoplasmic tail, 3
KIR2DL4 killer cell immunoglobulin-like receptor, two domains, long cytoplasmic tail, 4
KIR3DL2 killer cell immunoglobulin-like receptor, three domains, long cytoplasmic tail, 2
KLC3 kinesin light chain 3
KLK1 kallikrein 1
KRAS Kirsten rat sarcoma viral oncogene homolog
LACRT lacritin
LBP lipopolysaccharide binding protein
LGALS3 lectin, galactoside-binding, soluble, 3
LGALS7 lectin, galactoside-binding, soluble, 7
LGR5 leucine-rich repeat containing G protein-coupled receptor 5
LHCGR luteinizing hormone/choriogonadotropin receptor
LIG4 ligase IV, DNA, ATP-dependent
LIN28A lin-28 homolog A (C. elegans)
LINGO1 leucine rich repeat and Ig domain containing 1
LIPG lipase, endothelial
LMO2 LIM domain only 2 (rhombotin-like 1)
LPA lipoprotein, Lp(a)
LPL lipoprotein lipase
LRP1B low density lipoprotein receptor-related protein 1B
LRP6 low density lipoprotein receptor-related protein 6
LRRK2 leucine-rich repeat kinase 2
LRRTM3 leucine rich repeat transmembrane neuronal 3
LTB4R leukotriene B4 receptor
LY96 lymphocyte antigen 96
MAOA monoamine oxidase A
MAP2K4 mitogen-activated protein kinase kinase 4
MAPK1 mitogen-activated protein kinase 1
MAPK3 mitogen-activated protein kinase 3
MBL2 mannose-binding lectin (protein C) 2, soluble
MBP myelin basic protein
MDM2 MDM2 proto-oncogene, E3 ubiquitin protein ligase
MED15 mediator complex subunit 15
MEG3 maternally expressed 3 (non-protein coding)
MET MET proto-oncogene, receptor tyrosine kinase
MFSD8 major facilitator superfamily domain containing 8
MGMT O-6-methylguanine-DNA methyltransferase
MIR122 microRNA 122
MIR490 microRNA 490
MKI67 marker of proliferation Ki-67
MKS1 Meckel syndrome, type 1
MLANA melan-A
MLPH melanophilin
MMP9 matrix metallopeptidase 9
MPDZ multiple PDZ domain protein
MPL MPL proto-oncogene, thrombopoietin receptor
MSI1 musashi RNA-binding protein 1
MT1A metallothionein 1A
MTHFD1 methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 1, methenyltetrahydrofolate cyclohydrolase, formyltetrahydrofolate synthetase
MTHFR methylenetetrahydrofolate reductase (NAD(P)H)
MTRR 5-methyltetrahydrofolate-homocysteine methyltransferase reductase
MUC19 mucin 19, oligomeric
MUC4 mucin 4, cell surface associated
MYC v-myc avian myelocytomatosis viral oncogene homolog
MYCN v-myc avian myelocytomatosis viral oncogene neuroblastoma derived homolog
MYD88 myeloid differentiation primary response 88
MYLK myosin light chain kinase
MYO5A myosin VA (heavy chain 12, myoxin)
NAMPT nicotinamide phosphoribosyltransferase
NBL1 neuroblastoma 1, DAN family BMP antagonist
NBR1 neighbor of BRCA1 gene 1
NEO1 neogenin 1
NES nestin
NEWENTRY Record to support submission of GeneRIFs for a gene not in Gene (human; man).
NFE2L2 nuclear factor, erythroid 2-like 2
NKX3-1 NK3 homeobox 1
NLRP3 NLR family, pyrin domain containing 3
NOS3 nitric oxide synthase 3 (endothelial cell)
NOTCH3 notch 3
NPC2 Niemann-Pick disease, type C2
NPY2R neuropeptide Y receptor Y2
NQO1 NAD(P)H dehydrogenase, quinone 1
NR2E1 nuclear receptor subfamily 2, group E, member 1
NR3C2 nuclear receptor subfamily 3, group C, member 2
NRAS neuroblastoma RAS viral (v-ras) oncogene homolog
NRP2 neuropilin 2
NTN4 netrin 4
NTRK1 neurotrophic tyrosine kinase, receptor, type 1
NUP62 nucleoporin 62kDa
OLIG2 oligodendrocyte lineage transcription factor 2
P2RY14 purinergic receptor P2Y, G-protein coupled, 14
P3H1 prolyl 3-hydroxylase 1
PAFAH2 platelet-activating factor acetylhydrolase 2, 40kDa
PARK2 parkin RBR E3 ubiquitin protein ligase
PARK7 parkinson protein 7
PCSK1 proprotein convertase subtilisin/kexin type 1
PCSK2 proprotein convertase subtilisin/kexin type 2
PCSK6 proprotein convertase subtilisin/kexin type 6
PDHA1 pyruvate dehydrogenase (lipoamide) alpha 1
PDHA2 pyruvate dehydrogenase (lipoamide) alpha 2
PEBP1 phosphatidylethanolamine binding protein 1
PEMT phosphatidylethanolamine N-methyltransferase
PF4 platelet factor 4
PHLPP1 PH domain and leucine rich repeat protein phosphatase 1
PIK3CG phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit gamma
PIP prolactin-induced protein
PKP4 plakophilin 4
PLAC1 placenta-specific 1
PLAUR plasminogen activator, urokinase receptor
PLK4 polo-like kinase 4
PLN phospholamban
PLS3 plastin 3
POF1B premature ovarian failure, 1B
PON1 paraoxonase 1
POU4F1 POU class 4 homeobox 1
POU5F1 POU class 5 homeobox 1
PPARGC1A peroxisome proliferator-activated receptor gamma, coactivator 1 alpha
PPP1CA protein phosphatase 1, catalytic subunit, alpha isozyme
PPP2R2A protein phosphatase 2, regulatory subunit B, alpha
PPP2R5C protein phosphatase 2, regulatory subunit B', gamma
PPP2R5E protein phosphatase 2, regulatory subunit B', epsilon isoform
PRDM1 PR domain containing 1, with ZNF domain
PRKCI protein kinase C, iota
PRKDC protein kinase, DNA-activated, catalytic polypeptide
PRNP prion protein
PROM1 prominin 1
PRSS27 protease, serine 27
PSORS1C2 psoriasis susceptibility 1 candidate 2
PTEN phosphatase and tensin homolog
PTGDS prostaglandin D2 synthase 21kDa (brain)
PTGS2 prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase)
PUM1 pumilio RNA-binding family member 1
PVT1 Pvt1 oncogene (non-protein coding)
RAF1 Raf-1 proto-oncogene, serine/threonine kinase
RANBP2 RAN binding protein 2
REEP1 receptor accessory protein 1
REEP2 receptor accessory protein 2
RET ret proto-oncogene
RFX6 regulatory factor X, 6
RHO rhodopsin
RHOA ras homolog family member A
RMDN3 regulator of microtubule dynamics 3
RNF123 ring finger protein 123
RPGR retinitis pigmentosa GTPase regulator
RPGRIP1 retinitis pigmentosa GTPase regulator interacting protein 1
RRN3 RRN3 RNA polymerase I transcription factor homolog (S. cerevisiae)
RSPH1 radial spoke head 1 homolog (Chlamydomonas)
RTN4R reticulon 4 receptor
RXRG retinoid X receptor, gamma
S100A12 S100 calcium binding protein A12
S100A9 S100 calcium binding protein A9
SCGB1D2 secretoglobin, family 1D, member 2
SEMA4D sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4D
SERPINA9 serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 9
SERPINI1 serpin peptidase inhibitor, clade I (neuroserpin), member 1
SFRP5 secreted frizzled-related protein 5
SHC1 SHC (Src homology 2 domain containing) transforming protein 1
SHH sonic hedgehog
SIRT1 sirtuin 1
SLC22A6 solute carrier family 22 (organic anion transporter), member 6
SLC2A3 solute carrier family 2 (facilitated glucose transporter), member 3
SLC3A2 solute carrier family 3 (amino acid transporter heavy chain), member 2
SLC43A2 solute carrier family 43 (amino acid system L transporter), member 2
SLC5A5 solute carrier family 5 (sodium/iodide cotransporter), member 5
SLC6A4 solute carrier family 6 (neurotransmitter transporter), member 4
SLC9A3R2 solute carrier family 9, subfamily A (NHE3, cation proton antiporter 3), member 3 regulator 2
SLC9B2 solute carrier family 9, subfamily B (NHA2, cation proton antiporter 2), member 2
SMARCB1 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily b, member 1
SMC1A structural maintenance of chromosomes 1A
SMPDL3A sphingomyelin phosphodiesterase, acid-like 3A
SNCA synuclein, alpha (non A4 component of amyloid precursor)
SOD1 superoxide dismutase 1, soluble
SOX10 SRY (sex determining region Y)-box 10
SOX9 SRY (sex determining region Y)-box 9
SPP1 secreted phosphoprotein 1
SPPL2B signal peptide peptidase like 2B
SPPL3 signal peptide peptidase like 3
SRSF2 serine/arginine-rich splicing factor 2
STRA8 stimulated by retinoic acid 8
STX16 syntaxin 16
SYCP3 synaptonemal complex protein 3
TACR1 tachykinin receptor 1
TAP2 transporter 2, ATP-binding cassette, sub-family B (MDR/TAP)
TARDBP TAR DNA binding protein
TAS2R38 taste receptor, type 2, member 38
TCF4 transcription factor 4
TCF7L2 transcription factor 7-like 2 (T-cell specific, HMG-box)
TFAP2A transcription factor AP-2 alpha (activating enhancer binding protein 2 alpha)
TGFB1 transforming growth factor, beta 1
TGM1 transglutaminase 1
TGM2 transglutaminase 2
TIMD4 T-cell immunoglobulin and mucin domain containing 4
TINF2 TERF1 (TRF1)-interacting nuclear factor 2
TLR10 toll-like receptor 10
TLR2 toll-like receptor 2
TLR3 toll-like receptor 3
TLR4 toll-like receptor 4
TLR5 toll-like receptor 5
TMEM173 transmembrane protein 173
TMSB10 thymosin beta 10
TNF tumor necrosis factor
TNFRSF13C tumor necrosis factor receptor superfamily, member 13C
TNFRSF25 tumor necrosis factor receptor superfamily, member 25
TNFRSF8 tumor necrosis factor receptor superfamily, member 8
TNFSF11 tumor necrosis factor (ligand) superfamily, member 11
TNS1 tensin 1
TP53 tumor protein p53
TRA T cell receptor alpha locus
TRB T cell receptor beta locus
TRIM5 tripartite motif containing 5
TRO trophinin
TRPC2 transient receptor potential cation channel, subfamily C, member 2, pseudogene
TSC22D1 TSC22 domain family, member 1
TSHR thyroid stimulating hormone receptor
TYK2 tyrosine kinase 2
TYROBP TYRO protein tyrosine kinase binding protein
U2AF1 U2 small nuclear RNA auxiliary factor 1
UCHL1 ubiquitin carboxyl-terminal esterase L1 (ubiquitin thiolesterase)
VANGL1 VANGL planar cell polarity protein 1
VEGFA vascular endothelial growth factor A
VEGFB vascular endothelial growth factor B
VSIG1 V-set and immunoglobulin domain containing 1
VWF von Willebrand factor
WT1 Wilms tumor 1
XAGE1B X antigen family, member 1B
YBX2 Y box binding protein 2
YIPF5 Yip1 domain family, member 5
ZBTB33 zinc finger and BTB domain containing 33
ZNF382 zinc finger protein 382