resveratrol-622 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

199 genes differentially expressed following the resveratrol-622 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ACOT8 acyl-CoA thioesterase 8
ACTA2 actin, alpha 2, smooth muscle, aorta
ACVR1B activin A receptor, type IB
ADCK3 aarF domain containing kinase 3
AKIP1 A kinase (PRKA) interacting protein 1
ASNS asparagine synthetase (glutamine-hydrolyzing)
AZGP1 alpha-2-glycoprotein 1, zinc-binding
BBC3 BCL2 binding component 3
BTG2 BTG family, member 2
C21ORF2 chromosome 21 open reading frame 2
CACNG4 calcium channel, voltage-dependent, gamma subunit 4
CCNG2 cyclin G2
CD248 CD248 molecule, endosialin
CDKN1A cyclin-dependent kinase inhibitor 1A (p21, Cip1)
CHAC1 ChaC glutathione-specific gamma-glutamylcyclotransferase 1
CHMP5 charged multivesicular body protein 5
CREM cAMP responsive element modulator
DDIT3 DNA-damage-inducible transcript 3
DDIT4 DNA-damage-inducible transcript 4
DGKA diacylglycerol kinase, alpha 80kDa
DNAJC3 DnaJ (Hsp40) homolog, subfamily C, member 3
EIF2S3 eukaryotic translation initiation factor 2, subunit 3 gamma, 52kDa
EPOR erythropoietin receptor
ERN2 endoplasmic reticulum to nucleus signaling 2
EXTL3 exostosin-like glycosyltransferase 3
FAM182B family with sequence similarity 182, member B
FAM212B family with sequence similarity 212, member B
FAS Fas cell surface death receptor
FDXR ferredoxin reductase
FOSL2 FOS-like antigen 2
FURIN furin (paired basic amino acid cleaving enzyme)
GADD45A growth arrest and DNA-damage-inducible, alpha
GMPPB GDP-mannose pyrophosphorylase B
GOLGA4 golgin A4
GRK5 G protein-coupled receptor kinase 5
HCFC1R1 host cell factor C1 regulator 1 (XPO1 dependent)
HERPUD1 homocysteine-inducible, endoplasmic reticulum stress-inducible, ubiquitin-like domain member 1
HIST1H2AI histone cluster 1, H2ai
HIST1H3H histone cluster 1, H3h
HIST2H2BE histone cluster 2, H2be
HNF1A HNF1 homeobox A
HSD17B14 hydroxysteroid (17-beta) dehydrogenase 14
HSPA6 heat shock 70kDa protein 6 (HSP70B')
IER5 immediate early response 5
IFNGR1 interferon gamma receptor 1
KCNAB2 potassium channel, voltage gated subfamily A regulatory beta subunit 2
KDM4A lysine (K)-specific demethylase 4A
KIAA0141 KIAA0141
KIAA1109 KIAA1109
KLHL24 kelch-like family member 24
LZTR1 leucine-zipper-like transcription regulator 1
MANBA mannosidase, beta A, lysosomal
MBP myelin basic protein
MDM2 MDM2 proto-oncogene, E3 ubiquitin protein ligase
MR1 major histocompatibility complex, class I-related
MT1E metallothionein 1E
MT1F metallothionein 1F
MT1G metallothionein 1G
MT1HL1 metallothionein 1H-like 1
MTSS1 metastasis suppressor 1
NEAT1 nuclear paraspeckle assembly transcript 1 (non-protein coding)
NFKB2 nuclear factor of kappa light polypeptide gene enhancer in B-cells 2 (p49/p100)
ORAI3 ORAI calcium release-activated calcium modulator 3
OSGIN1 oxidative stress induced growth inhibitor 1
PCDHA10 protocadherin alpha 10
PDE6D phosphodiesterase 6D, cGMP-specific, rod, delta
PDXK pyridoxal (pyridoxine, vitamin B6) kinase
PEX7 peroxisomal biogenesis factor 7
PLCD1 phospholipase C, delta 1
PMAIP1 phorbol-12-myristate-13-acetate-induced protein 1
PMEPA1 prostate transmembrane protein, androgen induced 1
PMS2P2 postmeiotic segregation increased 2 pseudogene 2
PNRC1 proline-rich nuclear receptor coactivator 1
PSMB10 proteasome (prosome, macropain) subunit, beta type, 10
PTCRA pre T-cell antigen receptor alpha
PTP4A1 protein tyrosine phosphatase type IVA, member 1
PVT1 Pvt1 oncogene (non-protein coding)
PYGL phosphorylase, glycogen, liver
RPL13 ribosomal protein L13
RWDD2A RWD domain containing 2A
SEC61A2 Sec61 alpha 2 subunit (S. cerevisiae)
SIDT2 SID1 transmembrane family, member 2
SIRT5 sirtuin 5
SMIM8 small integral membrane protein 8
SPG21 spastic paraplegia 21 (autosomal recessive, Mast syndrome)
STRA6 stimulated by retinoic acid 6
STX5 syntaxin 5
TIPARP TCDD-inducible poly(ADP-ribose) polymerase
TMED9 transmembrane emp24 protein transport domain containing 9
TMEM80 transmembrane protein 80
TMPRSS15 transmembrane protease, serine 15
TNFRSF10B tumor necrosis factor receptor superfamily, member 10b
TNFRSF25 tumor necrosis factor receptor superfamily, member 25
TRIM8 tripartite motif containing 8
UFSP2 UFM1-specific peptidase 2
VRK3 vaccinia related kinase 3
ZNF444 zinc finger protein 444
ZNF446 zinc finger protein 446
ZNF652 zinc finger protein 652

decreased expression

Symbol Name
ADGRG6 adhesion G protein-coupled receptor G6
ADNP activity-dependent neuroprotector homeobox
AGPAT5 1-acylglycerol-3-phosphate O-acyltransferase 5
ARGLU1 arginine and glutamate rich 1
ARMT1 acidic residue methyltransferase 1
ASPM asp (abnormal spindle) homolog, microcephaly associated (Drosophila)
ATOX1 antioxidant 1 copper chaperone
BRD7 bromodomain containing 7
BUB1B BUB1 mitotic checkpoint serine/threonine kinase B
CCNA2 cyclin A2
CCNB1 cyclin B1
CDC20 cell division cycle 20
CDC23 cell division cycle 23
CDCA8 cell division cycle associated 8
CDR2L cerebellar degeneration-related protein 2-like
CENPE centromere protein E, 312kDa
CHKA choline kinase alpha
CHORDC1 cysteine and histidine-rich domain (CHORD) containing 1
CHRNA5 cholinergic receptor, nicotinic, alpha 5 (neuronal)
CIC capicua transcriptional repressor
CKS2 CDC28 protein kinase regulatory subunit 2
CNP 2',3'-cyclic nucleotide 3' phosphodiesterase
CTDSP1 CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) small phosphatase 1
CYP27B1 cytochrome P450, family 27, subfamily B, polypeptide 1
DBF4 DBF4 zinc finger
DCP2 decapping mRNA 2
DCTN4 dynactin 4 (p62)
DDX5 DEAD (Asp-Glu-Ala-Asp) box helicase 5
DENND4B DENN/MADD domain containing 4B
DEPDC1 DEP domain containing 1
DHX38 DEAH (Asp-Glu-Ala-His) box polypeptide 38
DLGAP5 discs, large (Drosophila) homolog-associated protein 5
EGLN2 egl-9 family hypoxia-inducible factor 2
EZH2 enhancer of zeste 2 polycomb repressive complex 2 subunit
FAM193A family with sequence similarity 193, member A
FAM64A family with sequence similarity 64, member A
GINS1 GINS complex subunit 1 (Psf1 homolog)
GPHN gephyrin
GPRC5C G protein-coupled receptor, class C, group 5, member C
GTPBP8 GTP-binding protein 8 (putative)
HOXC11 homeobox C11
HYAL2 hyaluronoglucosaminidase 2
ID1 inhibitor of DNA binding 1, dominant negative helix-loop-helix protein
ILF2 interleukin enhancer binding factor 2
IP6K2 inositol hexakisphosphate kinase 2
ITGAE integrin, alpha E (antigen CD103, human mucosal lymphocyte antigen 1; alpha polypeptide)
KIF11 kinesin family member 11
KIF14 kinesin family member 14
KIF18B kinesin family member 18B
KIF20A kinesin family member 20A
KIF20B kinesin family member 20B
KIF23 kinesin family member 23
KIF4A kinesin family member 4A
KPNA2 karyopherin alpha 2 (RAG cohort 1, importin alpha 1)
LAMA5 laminin, alpha 5
LBR lamin B receptor
LRFN4 leucine rich repeat and fibronectin type III domain containing 4
MAP7D1 MAP7 domain containing 1
MED15 mediator complex subunit 15
MELK maternal embryonic leucine zipper kinase
NHEJ1 nonhomologous end-joining factor 1
P2RY2 purinergic receptor P2Y, G-protein coupled, 2
PBX3 pre-B-cell leukemia homeobox 3
PHLDA2 pleckstrin homology-like domain, family A, member 2
PLK1 polo-like kinase 1
POLR3E polymerase (RNA) III (DNA directed) polypeptide E (80kD)
PPM1H protein phosphatase, Mg2+/Mn2+ dependent, 1H
PRC1 protein regulator of cytokinesis 1
PRPF38B pre-mRNA processing factor 38B
PSRC1 proline/serine-rich coiled-coil 1
RACGAP1 Rac GTPase activating protein 1
RBM15B RNA binding motif protein 15B
RBM42 RNA binding motif protein 42
RRS1 RRS1 ribosome biogenesis regulator homolog (S. cerevisiae)
SCML2 sex comb on midleg-like 2 (Drosophila)
SLC25A24 solute carrier family 25 (mitochondrial carrier; phosphate carrier), member 24
SLC25A32 solute carrier family 25 (mitochondrial folate carrier), member 32
SLC35A1 solute carrier family 35 (CMP-sialic acid transporter), member A1
SLC38A1 solute carrier family 38, member 1
SLC6A14 solute carrier family 6 (amino acid transporter), member 14
SLCO4A1 solute carrier organic anion transporter family, member 4A1
SMNDC1 survival motor neuron domain containing 1
SURF2 surfeit 2
TACC3 transforming, acidic coiled-coil containing protein 3
TCERG1 transcription elongation regulator 1
TMEM165 transmembrane protein 165
TOE1 target of EGR1, member 1 (nuclear)
TOP2A topoisomerase (DNA) II alpha 170kDa
TPX2 TPX2, microtubule-associated
TROAP trophinin associated protein
TTK TTK protein kinase
UBE2C ubiquitin-conjugating enzyme E2C
UBE2S ubiquitin-conjugating enzyme E2S
UGDH UDP-glucose 6-dehydrogenase
URB2 URB2 ribosome biogenesis 2 homolog (S. cerevisiae)
USB1 U6 snRNA biogenesis 1
UTP20 UTP20, small subunit (SSU) processome component, homolog (yeast)
VANGL1 VANGL planar cell polarity protein 1
ZHX2 zinc fingers and homeoboxes 2
ZIC1 Zic family member 1