retinal rod Gene Set

Dataset TISSUES Text-mining Tissue Protein Expression Evidence Scores
Category structural or functional annotations
Type tissue
Description Major photoreceptor cell of vertebrate retina (about 125 million in a human eye). Columnar cells having three distinct regions: a region adjacent to, and synapsed with, the neural layer of the retina contains the nucleus and other cytoplasmic organelles, below this is the inner segment, rich in mitochondria, that is connected through a thin neck (in which is located a ciliary body) to the outer segment. The outer segment largely consists of a stack of discs (membrane infoldings that are incompletely separated in cones) that are continually replenished near the inner segment and that are shed from the distal end and phagocytosed by the pigmented epithelium. The membranes of the discs are rich in rhodopsin, the pigment that absorbs light. (BRENDA Tissue and Enzyme Source Ontology, BTO_0001024)
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Genes

125 proteins co-occuring with the tissue retinal rod in abstracts of biomedical publications from the TISSUES Text-mining Tissue Protein Expression Evidence Scores dataset.

Symbol Name Standardized Value
RHO rhodopsin 3.57747
SLC24A1 solute carrier family 24 (sodium/potassium/calcium exchanger), member 1 2.36765
GRK1 G protein-coupled receptor kinase 1 2.25125
RCVRN recoverin 2.08028
SAG S-antigen; retina and pineal gland (arrestin) 1.76174
GUCY2C guanylate cyclase 2C 1.61111
NPR1 natriuretic peptide receptor 1 1.60813
PDE6A phosphodiesterase 6A, cGMP-specific, rod, alpha 1.46355
PDE6C phosphodiesterase 6C, cGMP-specific, cone, alpha prime 1.36496
PDE6B phosphodiesterase 6B, cGMP-specific, rod, beta 1.31153
PDC phosducin 1.2519
GUCY2D guanylate cyclase 2D, membrane (retina-specific) 1.22514
PDE11A phosphodiesterase 11A 1.20422
PDE5A phosphodiesterase 5A, cGMP-specific 1.14432
PPEF2 protein phosphatase, EF-hand calcium binding domain 2 1.11199
GUCA1B guanylate cyclase activator 1B (retina) 1.07265
ABCA4 ATP-binding cassette, sub-family A (ABC1), member 4 1.06779
GUCY1B2 guanylate cyclase 1, soluble, beta 2 (pseudogene) 1.03478
GUCY1A2 guanylate cyclase 1, soluble, alpha 2 1.03478
DMTN dematin actin binding protein 1.03083
PDE6G phosphodiesterase 6G, cGMP-specific, rod, gamma 1.02469
SRGN serglycin 1.019
OPN4 opsin 4 0.972417
GNA15 guanine nucleotide binding protein (G protein), alpha 15 (Gq class) 0.971119
GNA11 guanine nucleotide binding protein (G protein), alpha 11 (Gq class) 0.964199
CALM2 calmodulin 2 (phosphorylase kinase, delta) 0.95729
CALM3 calmodulin 3 (phosphorylase kinase, delta) 0.95729
CALM1 calmodulin 1 (phosphorylase kinase, delta) 0.955996
PDE10A phosphodiesterase 10A 0.946947
RP2 retinitis pigmentosa 2 (X-linked recessive) 0.940495
KCNV2 potassium channel, voltage gated modifier subfamily V, member 2 0.917779
CABP2 calcium binding protein 2 0.91308
CABP5 calcium binding protein 5 0.901573
ELOVL4 ELOVL fatty acid elongase 4 0.900721
GUCA1A guanylate cyclase activator 1A (retina) 0.87782
RHOD ras homolog family member D 0.875284
CRYGD crystallin, gamma D 0.857153
SLC24A5 solute carrier family 24 (sodium/potassium/calcium exchanger), member 5 0.856732
CERKL ceramide kinase-like 0.851266
GUCY2F guanylate cyclase 2F, retinal 0.845805
CABP4 calcium binding protein 4 0.837833
NME4 NME/NM23 nucleoside diphosphate kinase 4 0.837414
NME3 NME/NM23 nucleoside diphosphate kinase 3 0.837414
SLC8B1 solute carrier family 8 (sodium/lithium/calcium exchanger), member B1 0.826942
NMT2 N-myristoyltransferase 2 0.803961
RERG RAS-like, estrogen-regulated, growth inhibitor 0.792293
GUCY1A3 guanylate cyclase 1, soluble, alpha 3 0.756604
GNAT1 guanine nucleotide binding protein (G protein), alpha transducing activity polypeptide 1 0.743389
SLC24A4 solute carrier family 24 (sodium/potassium/calcium exchanger), member 4 0.737206
DOK3 docking protein 3 0.719524
PHLPP2 PH domain and leucine rich repeat protein phosphatase 2 0.704764
GUCY1B3 guanylate cyclase 1, soluble, beta 3 0.704764
GNAT2 guanine nucleotide binding protein (G protein), alpha transducing activity polypeptide 2 0.688817
SLC24A3 solute carrier family 24 (sodium/potassium/calcium exchanger), member 3 0.686776
ACER3 alkaline ceramidase 3 0.67984
AIPL1 aryl hydrocarbon receptor interacting protein-like 1 0.675765
CNGA1 cyclic nucleotide gated channel alpha 1 0.668436
PRCD progressive rod-cone degeneration 0.663149
SYNPR synaptoporin 0.633953
PRPH2 peripherin 2 (retinal degeneration, slow) 0.628293
NACA3P NACA family member 3 pseudogene 0.615377
SUCLG2 succinate-CoA ligase, GDP-forming, beta subunit 0.614571
HCN1 hyperpolarization activated cyclic nucleotide gated potassium channel 1 0.59646
PDE6D phosphodiesterase 6D, cGMP-specific, rod, delta 0.589234
NME2 NME/NM23 nucleoside diphosphate kinase 2 0.578016
GNB5 guanine nucleotide binding protein (G protein), beta 5 0.570021
RAB8A RAB8A, member RAS oncogene family 0.570021
GRB14 growth factor receptor-bound protein 14 0.561644
RGS11 regulator of G-protein signaling 11 0.56005
CRX cone-rod homeobox 0.544946
ARR3 arrestin 3, retinal (X-arrestin) 0.540585
NACA nascent polypeptide-associated complex alpha subunit 0.536625
NPR2 natriuretic peptide receptor 2 0.527139
CMAS cytidine monophosphate N-acetylneuraminic acid synthetase 0.494136
CHAD chondroadherin 0.489838
MGAM maltase-glucoamylase 0.484376
RGS7 regulator of G-protein signaling 7 0.483206
DNAH8 dynein, axonemal, heavy chain 8 0.482428
CNGB1 cyclic nucleotide gated channel beta 1 0.478534
CERK ceramide kinase 0.475812
ARRB1 arrestin, beta 1 0.471927
ENPP3 ectonucleotide pyrophosphatase/phosphodiesterase 3 0.460305
RBP3 retinol binding protein 3, interstitial 0.447576
PLCB2 phospholipase C, beta 2 0.442578
CNGA3 cyclic nucleotide gated channel alpha 3 0.439123
NGDN neuroguidin, EIF4E binding protein 0.434523
SLC8A1 solute carrier family 8 (sodium/calcium exchanger), member 1 0.430312
SAR1A secretion associated, Ras related GTPase 1A 0.428018
TRPM1 transient receptor potential cation channel, subfamily M, member 1 0.409731
CHIA chitinase, acidic 0.401765
GNB3 guanine nucleotide binding protein (G protein), beta polypeptide 3 0.401386
PIAS3 protein inhibitor of activated STAT, 3 0.400628
NR2E3 nuclear receptor subfamily 2, group E, member 3 0.393064
DDAH2 dimethylarginine dimethylaminohydrolase 2 0.392686
CTBP2 C-terminal binding protein 2 0.377996
GNB1 guanine nucleotide binding protein (G protein), beta polypeptide 1 0.376119
SLC26A2 solute carrier family 26 (anion exchanger), member 2 0.373493
SLC8A2 solute carrier family 8 (sodium/calcium exchanger), member 2 0.368998
CDH6 cadherin 6, type 2, K-cadherin (fetal kidney) 0.34963
ADCY4 adenylate cyclase 4 0.347038
OGN osteoglycin 0.331927
ADCY7 adenylate cyclase 7 0.331927
PDHX pyruvate dehydrogenase complex, component X 0.316951
ALYREF Aly/REF export factor 0.316224
ADCY5 adenylate cyclase 5 0.306083
SNED1 sushi, nidogen and EGF-like domains 1 0.302118
PDCL phosducin-like 0.298524
ADCY1 adenylate cyclase 1 (brain) 0.290652
ADCY9 adenylate cyclase 9 0.288514
ADCY3 adenylate cyclase 3 0.288158
PPA1 pyrophosphatase (inorganic) 1 0.283899
SDF4 stromal cell derived factor 4 0.271604
GUK1 guanylate kinase 1 0.269521
ENPP1 ectonucleotide pyrophosphatase/phosphodiesterase 1 0.244232
ADCY10 adenylate cyclase 10 (soluble) 0.242983
ASPN asporin 0.238706
CA2 carbonic anhydrase II 0.237513
NGB neuroglobin 0.236627
NRL neural retina leucine zipper 0.233162
ADCY8 adenylate cyclase 8 (brain) 0.229839
ANXA4 annexin A4 0.229299
PPEF1 protein phosphatase, EF-hand calcium binding domain 1 0.226667
ADCY6 adenylate cyclase 6 0.220378
TGM4 transglutaminase 4 0.219928
ADCY2 adenylate cyclase 2 (brain) 0.217554
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