retinopathy Gene Set

Dataset GeneRIF Biological Term Annotations
Category structural or functional annotations
Type biological term
Description Any disease or disorder of the retina. (Experimental Factor Ontology, EFO_0003839)
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Genes

185 genes co-occuring with the biological term retinopathy in literature-supported statements describing functions of genes from the GeneRIF Biological Term Annotations dataset.

Symbol Name
ABCA4 ATP-binding cassette, sub-family A (ABC1), member 4
ACAD9 acyl-CoA dehydrogenase family, member 9
ACE angiotensin I converting enzyme
ADIPOQ adiponectin, C1Q and collagen domain containing
AGER advanced glycosylation end product-specific receptor
AGK acylglycerol kinase
AGT angiotensinogen (serpin peptidase inhibitor, clade A, member 8)
AGTR1 angiotensin II receptor, type 1
AIRE autoimmune regulator
AKR1B1 aldo-keto reductase family 1, member B1 (aldose reductase)
AKR1B10 aldo-keto reductase family 1, member B10 (aldose reductase)
ALB albumin
ALDH2 aldehyde dehydrogenase 2 family (mitochondrial)
ALMS1 Alstrom syndrome protein 1
ANG angiogenin, ribonuclease, RNase A family, 5
ANGPT1 angiopoietin 1
ANGPT2 angiopoietin 2
AOC3 amine oxidase, copper containing 3
APLN apelin
APLNR apelin receptor
APOA1 apolipoprotein A-I
APOE apolipoprotein E
ARHGAP22 Rho GTPase activating protein 22
ARMS2 age-related maculopathy susceptibility 2
ATP6AP2 ATPase, H+ transporting, lysosomal accessory protein 2
ATXN1 ataxin 1
B4GALT2 UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 2
BDNF brain-derived neurotrophic factor
BEST1 bestrophin 1
BMP4 bone morphogenetic protein 4
BTC betacellulin
C1QTNF5 C1q and tumor necrosis factor related protein 5
CASP14 caspase 14, apoptosis-related cysteine peptidase
CCL2 chemokine (C-C motif) ligand 2
CCL5 chemokine (C-C motif) ligand 5
CD59 CD59 molecule, complement regulatory protein
CDH5 cadherin 5, type 2 (vascular endothelium)
CFB complement factor B
CFH complement factor H
CHN2 chimerin 2
CNR1 cannabinoid receptor 1 (brain)
COL4A5 collagen, type IV, alpha 5
CORT cortistatin
CPT1A carnitine palmitoyltransferase 1A (liver)
CPT1C carnitine palmitoyltransferase 1C
CPVL carboxypeptidase, vitellogenic-like
CRP C-reactive protein, pentraxin-related
CTGF connective tissue growth factor
CXCL10 chemokine (C-X-C motif) ligand 10
CXCL12 chemokine (C-X-C motif) ligand 12
CXCL8 chemokine (C-X-C motif) ligand 8
CXCL9 chemokine (C-X-C motif) ligand 9
CYBA cytochrome b-245, alpha polypeptide
CYP2C19 cytochrome P450, family 2, subfamily C, polypeptide 19
CYR61 cysteine-rich, angiogenic inducer, 61
EDN1 endothelin 1
ENG endoglin
ENO2 enolase 2 (gamma, neuronal)
ENPP2 ectonucleotide pyrophosphatase/phosphodiesterase 2
EPO erythropoietin
FAAH fatty acid amide hydrolase
FABP2 fatty acid binding protein 2, intestinal
FCN3 ficolin (collagen/fibrinogen domain containing) 3
FDPS farnesyl diphosphate synthase
FGF2 fibroblast growth factor 2 (basic)
FGF21 fibroblast growth factor 21
FLT1 fms-related tyrosine kinase 1
FZD4 frizzled class receptor 4
GDNF glial cell derived neurotrophic factor
GHRL ghrelin/obestatin prepropeptide
GHSR growth hormone secretagogue receptor
GLO1 glyoxalase I
GSTM1 glutathione S-transferase mu 1
GSTT1 glutathione S-transferase theta 1
HADHA hydroxyacyl-CoA dehydrogenase/3-ketoacyl-CoA thiolase/enoyl-CoA hydratase (trifunctional protein), alpha subunit
HBA1 hemoglobin, alpha 1
HDAC9 histone deacetylase 9
HGF hepatocyte growth factor (hepapoietin A; scatter factor)
HIF1A hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor)
HLA-A major histocompatibility complex, class I, A
HLA-B major histocompatibility complex, class I, B
HLA-DQA1 major histocompatibility complex, class II, DQ alpha 1
HLA-DQB1 major histocompatibility complex, class II, DQ beta 1
HLA-DRB1 major histocompatibility complex, class II, DR beta 1
HMGB1 high mobility group box 1
HP haptoglobin
ICAM1 intercellular adhesion molecule 1
IFNG interferon, gamma
IGF1 insulin-like growth factor 1 (somatomedin C)
IGF1R insulin-like growth factor 1 receptor
IGFBP3 insulin-like growth factor binding protein 3
IL10 interleukin 10
IL17A interleukin 17A
IL18 interleukin 18
IL1R1 interleukin 1 receptor, type I
IL6 interleukin 6
INS insulin
ITGA2 integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor)
ITGB3 integrin, beta 3 (platelet glycoprotein IIIa, antigen CD61)
KCNV2 potassium channel, voltage gated modifier subfamily V, member 2
KIT v-kit Hardy-Zuckerman 4 feline sarcoma viral oncogene homolog
KITLG KIT ligand
LAMP2 lysosomal-associated membrane protein 2
LIPG lipase, endothelial
LRP5 low density lipoprotein receptor-related protein 5
LTA lymphotoxin alpha
MAPK3 mitogen-activated protein kinase 3
MIR195 microRNA 195
MLXIPL MLX interacting protein-like
MME membrane metallo-endopeptidase
MMP10 matrix metallopeptidase 10
MMP2 matrix metallopeptidase 2
MMP9 matrix metallopeptidase 9
MTHFR methylenetetrahydrofolate reductase (NAD(P)H)
MYO7A myosin VIIA
NAA15 N(alpha)-acetyltransferase 15, NatA auxiliary subunit
NAMPT nicotinamide phosphoribosyltransferase
NDP Norrie disease (pseudoglioma)
NEUROD1 neuronal differentiation 1
NFKB1 nuclear factor of kappa light polypeptide gene enhancer in B-cells 1
NOS2 nitric oxide synthase 2, inducible
NOS3 nitric oxide synthase 3 (endothelial cell)
PF4 platelet factor 4
PGF placental growth factor
PLXDC1 plexin domain containing 1
PLXDC2 plexin domain containing 2
PLXND1 plexin D1
PML promyelocytic leukemia
PON1 paraoxonase 1
PON2 paraoxonase 2
POSTN periostin, osteoblast specific factor
PPARG peroxisome proliferator-activated receptor gamma
PRKCB protein kinase C, beta
PRKCD protein kinase C, delta
PRL prolactin
PROM1 prominin 1
PSMD9 proteasome (prosome, macropain) 26S subunit, non-ATPase, 9
PTGS2 prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase)
PTX3 pentraxin 3, long
RBP4 retinol binding protein 4, plasma
RCVRN recoverin
RDH5 retinol dehydrogenase 5 (11-cis/9-cis)
REN renin
ROBO1 roundabout, axon guidance receptor, homolog 1 (Drosophila)
ROBO4 roundabout, axon guidance receptor, homolog 4 (Drosophila)
ROCK2 Rho-associated, coiled-coil containing protein kinase 2
RXRG retinoid X receptor, gamma
SELE selectin E
SELL selectin L
SEMA3A sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3A
SEMA3E sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3E
SERPINE1 serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1
SERPINF1 serpin peptidase inhibitor, clade F (alpha-2 antiplasmin, pigment epithelium derived factor), member 1
SERPINF2 serpin peptidase inhibitor, clade F (alpha-2 antiplasmin, pigment epithelium derived factor), member 2
SIRT1 sirtuin 1
SLC2A1 solute carrier family 2 (facilitated glucose transporter), member 1
SLIT2 slit homolog 2 (Drosophila)
SOD1 superoxide dismutase 1, soluble
SOD2 superoxide dismutase 2, mitochondrial
SORD sorbitol dehydrogenase
SP1 Sp1 transcription factor
SPARC secreted protein, acidic, cysteine-rich (osteonectin)
SST somatostatin
SUCNR1 succinate receptor 1
SUMO4 small ubiquitin-like modifier 4
SUV39H2 suppressor of variegation 3-9 homolog 2 (Drosophila)
TCF7L2 transcription factor 7-like 2 (T-cell specific, HMG-box)
TEAD4 TEA domain family member 4
TEK TEK tyrosine kinase, endothelial
TERT telomerase reverse transcriptase
TGFB1 transforming growth factor, beta 1
THBS2 thrombospondin 2
TIMP3 TIMP metallopeptidase inhibitor 3
TLR4 toll-like receptor 4
TNC tenascin C
TNF tumor necrosis factor
TNFRSF11B tumor necrosis factor receptor superfamily, member 11b
TRPM1 transient receptor potential cation channel, subfamily M, member 1
UTS2 urotensin 2
VASH1 vasohibin 1
VCAM1 vascular cell adhesion molecule 1
VDR vitamin D (1,25- dihydroxyvitamin D3) receptor
VEGFA vascular endothelial growth factor A
VPS13B vacuolar protein sorting 13 homolog B (yeast)
VWF von Willebrand factor