rgs4 Gene Set

Dataset GeneRIF Biological Term Annotations
Category structural or functional annotations
Type biological term
Description regulator of G-protein signaling 4|Regulator of G protein signaling (RGS) family members are regulatory molecules that act as GTPase activating proteins (GAPs) for G alpha subunits of heterotrimeric G proteins. RGS proteins are able to deactivate G protein subunits of the Gi alpha, Go alpha and Gq alpha subtypes. They drive G proteins into their inactive GDP-bound forms. Regulator of G protein signaling 4 belongs to this family. All RGS proteins share a conserved 120-amino acid sequence termed the RGS domain. Regulator of G protein signaling 4 protein is 37% identical to RGS1 and 97% identical to rat Rgs4. This protein negatively regulate signaling upstream or at the level of the heterotrimeric G protein and is localized in the cytoplasm. Alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Jul 2008] (NCBI Entrez Gene Database, 5999)
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Genes

31 genes co-occuring with the biological term rgs4 in literature-supported statements describing functions of genes from the GeneRIF Biological Term Annotations dataset.

Symbol Name
ATF3 activating transcription factor 3
BCL6 B-cell CLL/lymphoma 6
COMT catechol-O-methyltransferase
DAOA D-amino acid oxidase activator
DAOA-AS1 DAOA antisense RNA 1
DISC1 disrupted in schizophrenia 1
DTNBP1 dystrobrevin binding protein 1
F2R coagulation factor II (thrombin) receptor
FEZ1 fasciculation and elongation protein zeta 1 (zygin I)
GAD1 glutamate decarboxylase 1 (brain, 67kDa)
GRM3 glutamate receptor, metabotropic 3
IKBKB inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase beta
MUC5AC mucin 5AC, oligomeric mucus/gel-forming
NFKB1 nuclear factor of kappa light polypeptide gene enhancer in B-cells 1
NFKBIA nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha
NFYA nuclear transcription factor Y, alpha
NRG1 neuregulin 1
OPRD1 opioid receptor, delta 1
OPRM1 opioid receptor, mu 1
PIP4K2A phosphatidylinositol-5-phosphate 4-kinase, type II, alpha
PRODH proline dehydrogenase (oxidase) 1
RAB11A RAB11A, member RAS oncogene family
RAB5A RAB5A, member RAS oncogene family
RAB7A RAB7A, member RAS oncogene family
RGS10 regulator of G-protein signaling 10
RGS16 regulator of G-protein signaling 16
RGS2 regulator of G-protein signaling 2
RGS3 regulator of G-protein signaling 3
RGS4 regulator of G-protein signaling 4
RGS5 regulator of G-protein signaling 5
UHMK1 U2AF homology motif (UHM) kinase 1