rheumatic disease Gene Set

Dataset GWASdb SNP-Disease Associations
Category disease or phenotype associations
Type disease
External Link http://jjwanglab.org/gwasdb/gwasdb2/gwasdb2/go_trait/DOID:1575
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Genes

86 genes associated with the disease rheumatic disease in GWAS and other genetic association datasets from the GWASdb SNP-Disease Associations dataset.

Symbol Name Standardized Value
HLA-DRA major histocompatibility complex, class II, DR alpha 1.75765
STAT4 signal transducer and activator of transcription 4 1.67541
NOTCH4 notch 4 1.57715
HLA-DPA1 major histocompatibility complex, class II, DP alpha 1 1.56661
TNIP1 TNFAIP3 interacting protein 1 1.42467
TNPO3 transportin 3 1.24855
IL12RB2 interleukin 12 receptor, beta 2 1.07513
SOX5 SRY (sex determining region Y)-box 5 1.03371
ITGAM integrin, alpha M (complement component 3 receptor 3 subunit) 1.0279
PXK PX domain containing serine/threonine kinase 1.00275
KIAA0319L KIAA0319-like 0.958374
PSORS1C1 psoriasis susceptibility 1 candidate 1 0.856349
LOC100506023 uncharacterized LOC100506023 0.769438
AGER advanced glycosylation end product-specific receptor 0.759653
TNXB tenascin XB 0.758332
CD247 CD247 molecule 0.75119
HLA-DPB1 major histocompatibility complex, class II, DP beta 1 0.699021
C10ORF11 chromosome 10 open reading frame 11 0.671708
JAZF1 JAZF zinc finger 1 0.638262
HSPA1L heat shock 70kDa protein 1-like 0.565204
SAMD9L sterile alpha motif domain containing 9-like 0.555938
STK19 serine/threonine kinase 19 0.55063
ANKS1A ankyrin repeat and sterile alpha motif domain containing 1A 0.539904
HLA-DQB2 major histocompatibility complex, class II, DQ beta 2 0.539099
ATG5 autophagy related 5 0.519576
AVEN apoptosis, caspase activation inhibitor 0.517605
LINC00305 long intergenic non-protein coding RNA 305 0.509883
MSH5 mutS homolog 5 0.509179
GRB2 growth factor receptor-bound protein 2 0.501056
PHRF1 PHD and ring finger domains 1 0.497346
GRB10 growth factor receptor-bound protein 10 0.496271
CLCA1 chloride channel accessory 1 0.494845
BANP BTG3 associated nuclear protein 0.492503
MACROD2 MACRO domain containing 2 0.492088
C6ORF10 chromosome 6 open reading frame 10 0.489227
RAMP1 receptor (G protein-coupled) activity modifying protein 1 0.488023
CNTNAP2 contactin associated protein-like 2 0.487202
BBS5 Bardet-Biedl syndrome 5 0.486518
GRK4 G protein-coupled receptor kinase 4 0.484681
PRRC2A proline-rich coiled-coil 2A 0.482679
UPK1B uroplakin 1B 0.482044
DPH2 DPH2 homolog (S. cerevisiae) 0.481775
ABCC9 ATP-binding cassette, sub-family C (CFTR/MRP), member 9 0.481611
STPG2 sperm-tail PG-rich repeat containing 2 0.481515
TTC7A tetratricopeptide repeat domain 7A 0.481276
RHPN2 rhophilin, Rho GTPase binding protein 2 0.480464
TMTC1 transmembrane and tetratricopeptide repeat containing 1 0.480358
PDE4B phosphodiesterase 4B, cAMP-specific 0.479798
ANKRD44 ankyrin repeat domain 44 0.477968
ITPR1 inositol 1,4,5-trisphosphate receptor, type 1 0.476686
LAMC2 laminin, gamma 2 0.476572
OPCML opioid binding protein/cell adhesion molecule-like 0.474551
IKZF3 IKAROS family zinc finger 3 (Aiolos) 0.473391
CDH18 cadherin 18, type 2 0.469512
DYSF dysferlin 0.469142
ICA1 islet cell autoantigen 1, 69kDa 0.465507
ADARB2 adenosine deaminase, RNA-specific, B2 (non-functional) 0.464999
UBE2L3 ubiquitin-conjugating enzyme E2L 3 0.464937
SMAD3 SMAD family member 3 0.464876
CNDP2 CNDP dipeptidase 2 (metallopeptidase M20 family) 0.463999
SORCS2 sortilin-related VPS10 domain containing receptor 2 0.463943
DGKQ diacylglycerol kinase, theta 110kDa 0.462899
RBMS3 RNA binding motif, single stranded interacting protein 3 0.462498
ASAP1 ArfGAP with SH3 domain, ankyrin repeat and PH domain 1 0.46233
BANK1 B-cell scaffold protein with ankyrin repeats 1 0.462055
ZNF423 zinc finger protein 423 0.460301
SLIT3 slit homolog 3 (Drosophila) 0.458704
WBSCR17 Williams-Beuren syndrome chromosome region 17 0.45627
CACNA2D1 calcium channel, voltage-dependent, alpha 2/delta subunit 1 0.455369
SFSWAP splicing factor, suppressor of white-apricot family 0.446629
ARMC9 armadillo repeat containing 9 0.443289
TSPAN16 tetraspanin 16 0.443021
IRAK2 interleukin-1 receptor-associated kinase 2 0.442858
NOL10 nucleolar protein 10 0.442423
CHODL chondrolectin 0.441932
NPAS3 neuronal PAS domain protein 3 0.441779
C1QB complement component 1, q subcomponent, B chain 0.440805
SUSD3 sushi domain containing 3 0.440237
CADPS2 Ca++-dependent secretion activator 2 0.439824
FBXO32 F-box protein 32 0.439785
HPGDS hematopoietic prostaglandin D synthase 0.439458
AKAP2 A kinase (PRKA) anchor protein 2 0.428917
TMEM39A transmembrane protein 39A 0.422053
RSBN1 round spermatid basic protein 1 0.42006
FCGR2A Fc fragment of IgG, low affinity IIa, receptor (CD32) 0.408512
MCAT malonyl CoA:ACP acyltransferase (mitochondrial) 0.405313