| Symbol |
Name |
|
ABCA1
|
ATP-binding cassette, sub-family A (ABC1), member 1
|
|
ABL2
|
ABL proto-oncogene 2, non-receptor tyrosine kinase
|
|
ACTA1
|
actin, alpha 1, skeletal muscle
|
|
ACTA2
|
actin, alpha 2, smooth muscle, aorta
|
|
ACTN4
|
actinin, alpha 4
|
|
ADORA3
|
adenosine A3 receptor
|
|
ADRB2
|
adrenoceptor beta 2, surface
|
|
AGAP3
|
ArfGAP with GTPase domain, ankyrin repeat and PH domain 3
|
|
AGT
|
angiotensinogen (serpin peptidase inhibitor, clade A, member 8)
|
|
AKAP13
|
A kinase (PRKA) anchor protein 13
|
|
AKT1
|
v-akt murine thymoma viral oncogene homolog 1
|
|
ANGPT1
|
angiopoietin 1
|
|
APP
|
amyloid beta (A4) precursor protein
|
|
AR
|
androgen receptor
|
|
ARAP2
|
ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 2
|
|
ARF6
|
ADP-ribosylation factor 6
|
|
ARG2
|
arginase 2
|
|
ARHGAP1
|
Rho GTPase activating protein 1
|
|
ARHGAP18
|
Rho GTPase activating protein 18
|
|
ARHGAP26
|
Rho GTPase activating protein 26
|
|
ARHGAP32
|
Rho GTPase activating protein 32
|
|
ARHGAP35
|
Rho GTPase activating protein 35
|
|
ARHGAP4
|
Rho GTPase activating protein 4
|
|
ARHGAP44
|
Rho GTPase activating protein 44
|
|
ARHGAP5
|
Rho GTPase activating protein 5
|
|
ARHGAP6
|
Rho GTPase activating protein 6
|
|
ARHGDIA
|
Rho GDP dissociation inhibitor (GDI) alpha
|
|
ARHGDIB
|
Rho GDP dissociation inhibitor (GDI) beta
|
|
ARHGEF1
|
Rho guanine nucleotide exchange factor (GEF) 1
|
|
ARHGEF11
|
Rho guanine nucleotide exchange factor (GEF) 11
|
|
ARHGEF12
|
Rho guanine nucleotide exchange factor (GEF) 12
|
|
ARHGEF18
|
Rho/Rac guanine nucleotide exchange factor (GEF) 18
|
|
ARHGEF2
|
Rho/Rac guanine nucleotide exchange factor (GEF) 2
|
|
ARHGEF25
|
Rho guanine nucleotide exchange factor (GEF) 25
|
|
ARHGEF3
|
Rho guanine nucleotide exchange factor (GEF) 3
|
|
ARHGEF5
|
Rho guanine nucleotide exchange factor (GEF) 5
|
|
ARHGEF7
|
Rho guanine nucleotide exchange factor (GEF) 7
|
|
ARL2BP
|
ADP-ribosylation factor-like 2 binding protein
|
|
ARRB1
|
arrestin, beta 1
|
|
ARSB
|
arylsulfatase B
|
|
AURKA
|
aurora kinase A
|
|
AURKB
|
aurora kinase B
|
|
BBS4
|
Bardet-Biedl syndrome 4
|
|
BIRC2
|
baculoviral IAP repeat containing 2
|
|
BIRC3
|
baculoviral IAP repeat containing 3
|
|
BTRC
|
beta-transducin repeat containing E3 ubiquitin protein ligase
|
|
BVES
|
blood vessel epicardial substance
|
|
CAMK2D
|
calcium/calmodulin-dependent protein kinase II delta
|
|
CAMP
|
cathelicidin antimicrobial peptide
|
|
CAPN2
|
calpain 2, (m/II) large subunit
|
|
CCDC125
|
coiled-coil domain containing 125
|
|
CCL11
|
chemokine (C-C motif) ligand 11
|
|
CCL17
|
chemokine (C-C motif) ligand 17
|
|
CCM2
|
cerebral cavernous malformation 2
|
|
CCNA1
|
cyclin A1
|
|
CCNA2
|
cyclin A2
|
|
CCND1
|
cyclin D1
|
|
CCR4
|
chemokine (C-C motif) receptor 4
|
|
CD151
|
CD151 molecule (Raph blood group)
|
|
CD44
|
CD44 molecule (Indian blood group)
|
|
CDC42
|
cell division cycle 42
|
|
CDH1
|
cadherin 1, type 1, E-cadherin (epithelial)
|
|
CDH5
|
cadherin 5, type 2 (vascular endothelium)
|
|
CDK1
|
cyclin-dependent kinase 1
|
|
CDKN1B
|
cyclin-dependent kinase inhibitor 1B (p27, Kip1)
|
|
CDKN1C
|
cyclin-dependent kinase inhibitor 1C (p57, Kip2)
|
|
CES1
|
carboxylesterase 1
|
|
CGNL1
|
cingulin-like 1
|
|
CIT
|
citron rho-interacting serine/threonine kinase
|
|
CKAP2
|
cytoskeleton associated protein 2
|
|
CLIC4
|
chloride intracellular channel 4
|
|
CNKSR1
|
connector enhancer of kinase suppressor of Ras 1
|
|
CNR1
|
cannabinoid receptor 1 (brain)
|
|
CNR2
|
cannabinoid receptor 2 (macrophage)
|
|
CREB1
|
cAMP responsive element binding protein 1
|
|
CSF2
|
colony stimulating factor 2 (granulocyte-macrophage)
|
|
CTGF
|
connective tissue growth factor
|
|
CTNNA1
|
catenin (cadherin-associated protein), alpha 1, 102kDa
|
|
CTNND1
|
catenin (cadherin-associated protein), delta 1
|
|
CTSB
|
cathepsin B
|
|
CTTN
|
cortactin
|
|
CUL3
|
cullin 3
|
|
CXCL12
|
chemokine (C-X-C motif) ligand 12
|
|
CXCL8
|
chemokine (C-X-C motif) ligand 8
|
|
CYR61
|
cysteine-rich, angiogenic inducer, 61
|
|
DEF6
|
differentially expressed in FDCP 6 homolog (mouse)
|
|
DIAPH1
|
diaphanous-related formin 1
|
|
DLC1
|
DLC1 Rho GTPase activating protein
|
|
DLG1
|
discs, large homolog 1 (Drosophila)
|
|
DYNLRB1
|
dynein, light chain, roadblock-type 1
|
|
ECT2
|
epithelial cell transforming 2
|
|
EDN1
|
endothelin 1
|
|
EFNB1
|
ephrin-B1
|
|
EGF
|
epidermal growth factor
|
|
EGFR
|
epidermal growth factor receptor
|
|
EIF4E
|
eukaryotic translation initiation factor 4E
|
|
EIF5A2
|
eukaryotic translation initiation factor 5A2
|
|
EPHA2
|
EPH receptor A2
|
|
ERBB2
|
erb-b2 receptor tyrosine kinase 2
|
|
ESR1
|
estrogen receptor 1
|
|
EXOC1
|
exocyst complex component 1
|
|
EXOC4
|
exocyst complex component 4
|
|
EZR
|
ezrin
|
|
F2R
|
coagulation factor II (thrombin) receptor
|
|
F2RL1
|
coagulation factor II (thrombin) receptor-like 1
|
|
F3
|
coagulation factor III (thromboplastin, tissue factor)
|
|
FAP
|
fibroblast activation protein, alpha
|
|
FDPS
|
farnesyl diphosphate synthase
|
|
FERMT3
|
fermitin family member 3
|
|
FLCN
|
folliculin
|
|
FLNA
|
filamin A, alpha
|
|
GAB2
|
GRB2-associated binding protein 2
|
|
GLI1
|
GLI family zinc finger 1
|
|
GMIP
|
GEM interacting protein
|
|
GNA13
|
guanine nucleotide binding protein (G protein), alpha 13
|
|
GNAQ
|
guanine nucleotide binding protein (G protein), q polypeptide
|
|
GOLPH3
|
golgi phosphoprotein 3 (coat-protein)
|
|
GPR55
|
G protein-coupled receptor 55
|
|
GRB2
|
growth factor receptor-bound protein 2
|
|
HAX1
|
HCLS1 associated protein X-1
|
|
HIF1A
|
hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor)
|
|
HRAS
|
Harvey rat sarcoma viral oncogene homolog
|
|
HRH1
|
histamine receptor H1
|
|
HSPA1A
|
heat shock 70kDa protein 1A
|
|
HSPA1B
|
heat shock 70kDa protein 1B
|
|
HSPB1
|
heat shock 27kDa protein 1
|
|
HSPB6
|
heat shock protein, alpha-crystallin-related, B6
|
|
HSPB7
|
heat shock 27kDa protein family, member 7 (cardiovascular)
|
|
HSPB8
|
heat shock 22kDa protein 8
|
|
ICAM1
|
intercellular adhesion molecule 1
|
|
ICAM2
|
intercellular adhesion molecule 2
|
|
ICMT
|
isoprenylcysteine carboxyl methyltransferase
|
|
IKBKB
|
inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase beta
|
|
IKBKG
|
inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase gamma
|
|
IL13
|
interleukin 13
|
|
IL4
|
interleukin 4
|
|
INPPL1
|
inositol polyphosphate phosphatase-like 1
|
|
IQGAP1
|
IQ motif containing GTPase activating protein 1
|
|
ITGA2B
|
integrin, alpha 2b (platelet glycoprotein IIb of IIb/IIIa complex, antigen CD41)
|
|
ITGA5
|
integrin, alpha 5 (fibronectin receptor, alpha polypeptide)
|
|
ITGA6
|
integrin, alpha 6
|
|
ITGAV
|
integrin, alpha V
|
|
ITGB1
|
integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12)
|
|
ITGB3
|
integrin, beta 3 (platelet glycoprotein IIIa, antigen CD61)
|
|
ITGB4
|
integrin, beta 4
|
|
JUN
|
jun proto-oncogene
|
|
KANK1
|
KN motif and ankyrin repeat domains 1
|
|
KISS1
|
KiSS-1 metastasis-suppressor
|
|
KLF2
|
Kruppel-like factor 2
|
|
LAMTOR1
|
late endosomal/lysosomal adaptor, MAPK and MTOR activator 1
|
|
LIPG
|
lipase, endothelial
|
|
LPAR1
|
lysophosphatidic acid receptor 1
|
|
LPAR2
|
lysophosphatidic acid receptor 2
|
|
MAGI3
|
membrane associated guanylate kinase, WW and PDZ domain containing 3
|
|
MAP2K1
|
mitogen-activated protein kinase kinase 1
|
|
MAP3K1
|
mitogen-activated protein kinase kinase kinase 1, E3 ubiquitin protein ligase
|
|
MAPK1
|
mitogen-activated protein kinase 1
|
|
MAPK14
|
mitogen-activated protein kinase 14
|
|
MAPK3
|
mitogen-activated protein kinase 3
|
|
MAPK8
|
mitogen-activated protein kinase 8
|
|
MCF2
|
MCF.2 cell line derived transforming sequence
|
|
MIR182
|
microRNA 182
|
|
MIR185
|
microRNA 185
|
|
MIR31
|
microRNA 31
|
|
MIR340
|
microRNA 340
|
|
MIR34A
|
microRNA 34a
|
|
MKKS
|
McKusick-Kaufman syndrome
|
|
MKL1
|
megakaryoblastic leukemia (translocation) 1
|
|
MME
|
membrane metallo-endopeptidase
|
|
MMP14
|
matrix metallopeptidase 14 (membrane-inserted)
|
|
MMP2
|
matrix metallopeptidase 2
|
|
MMP9
|
matrix metallopeptidase 9
|
|
MPRIP
|
myosin phosphatase Rho interacting protein
|
|
MSN
|
moesin
|
|
MTSS1
|
metastasis suppressor 1
|
|
MURC
|
muscle-related coiled-coil protein
|
|
MVK
|
mevalonate kinase
|
|
MYC
|
v-myc avian myelocytomatosis viral oncogene homolog
|
|
MYO9A
|
myosin IXA
|
|
NCK1
|
NCK adaptor protein 1
|
|
NCK2
|
NCK adaptor protein 2
|
|
NEDD9
|
neural precursor cell expressed, developmentally down-regulated 9
|
|
NEO1
|
neogenin 1
|
|
NET1
|
neuroepithelial cell transforming 1
|
|
NEWENTRY
|
Record to support submission of GeneRIFs for a gene not in Gene (human; man).
|
|
NFE2L2
|
nuclear factor, erythroid 2-like 2
|
|
NFKB1
|
nuclear factor of kappa light polypeptide gene enhancer in B-cells 1
|
|
NFKBIA
|
nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha
|
|
NGEF
|
neuronal guanine nucleotide exchange factor
|
|
NOS3
|
nitric oxide synthase 3 (endothelial cell)
|
|
NTN1
|
netrin 1
|
|
NUCLEOLIN
|
nucleolin multifunctional protein
|
|
OCRL
|
oculocerebrorenal syndrome of Lowe
|
|
OLIG2
|
oligodendrocyte lineage transcription factor 2
|
|
OLR1
|
oxidized low density lipoprotein (lectin-like) receptor 1
|
|
ORAI1
|
ORAI calcium release-activated calcium modulator 1
|
|
P2RX7
|
purinergic receptor P2X, ligand gated ion channel, 7
|
|
PAG1
|
phosphoprotein membrane anchor with glycosphingolipid microdomains 1
|
|
PARD6A
|
par-6 family cell polarity regulator alpha
|
|
PDGFRA
|
platelet-derived growth factor receptor, alpha polypeptide
|
|
PDPN
|
podoplanin
|
|
PGGT1B
|
protein geranylgeranyltransferase type I, beta subunit
|
|
PHF8
|
PHD finger protein 8
|
|
PIK3CA
|
phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit alpha
|
|
PIK3CB
|
phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit beta
|
|
PKN1
|
protein kinase N1
|
|
PKN2
|
protein kinase N2
|
|
PKP2
|
plakophilin 2
|
|
PKP4
|
plakophilin 4
|
|
PLAU
|
plasminogen activator, urokinase
|
|
PLCD1
|
phospholipase C, delta 1
|
|
PLCG1
|
phospholipase C, gamma 1
|
|
PLD1
|
phospholipase D1, phosphatidylcholine-specific
|
|
PLD2
|
phospholipase D2
|
|
PLEKHG6
|
pleckstrin homology domain containing, family G (with RhoGef domain) member 6
|
|
PLK1
|
polo-like kinase 1
|
|
PLXNB1
|
plexin B1
|
|
PPARG
|
peroxisome proliferator-activated receptor gamma
|
|
PPP1R12C
|
protein phosphatase 1, regulatory subunit 12C
|
|
PRC1
|
protein regulator of cytokinesis 1
|
|
PRKACA
|
protein kinase, cAMP-dependent, catalytic, alpha
|
|
PRKCA
|
protein kinase C, alpha
|
|
PRKCD
|
protein kinase C, delta
|
|
PRKCE
|
protein kinase C, epsilon
|
|
PRKCZ
|
protein kinase C, zeta
|
|
PRKD1
|
protein kinase D1
|
|
PRKG1
|
protein kinase, cGMP-dependent, type I
|
|
PRKG2
|
protein kinase, cGMP-dependent, type II
|
|
PRUNE2
|
prune homolog 2 (Drosophila)
|
|
PTGES
|
prostaglandin E synthase
|
|
PTK2
|
protein tyrosine kinase 2
|
|
PTK6
|
protein tyrosine kinase 6
|
|
PTP4A1
|
protein tyrosine phosphatase type IVA, member 1
|
|
PTP4A3
|
protein tyrosine phosphatase type IVA, member 3
|
|
PTPN11
|
protein tyrosine phosphatase, non-receptor type 11
|
|
RAC1
|
ras-related C3 botulinum toxin substrate 1 (rho family, small GTP binding protein Rac1)
|
|
RACGAP1
|
Rac GTPase activating protein 1
|
|
RAP1A
|
RAP1A, member of RAS oncogene family
|
|
RAP1GDS1
|
RAP1, GTP-GDP dissociation stimulator 1
|
|
RAPGEF3
|
Rap guanine nucleotide exchange factor (GEF) 3
|
|
RASA1
|
RAS p21 protein activator (GTPase activating protein) 1
|
|
RGS3
|
regulator of G-protein signaling 3
|
|
RHOA
|
ras homolog family member A
|
|
RHOB
|
ras homolog family member B
|
|
RHOC
|
ras homolog family member C
|
|
RHOD
|
ras homolog family member D
|
|
RHPN2
|
rhophilin, Rho GTPase binding protein 2
|
|
RND2
|
Rho family GTPase 2
|
|
RND3
|
Rho family GTPase 3
|
|
ROCK1
|
Rho-associated, coiled-coil containing protein kinase 1
|
|
ROCK2
|
Rho-associated, coiled-coil containing protein kinase 2
|
|
RTKN
|
rhotekin
|
|
RTN4
|
reticulon 4
|
|
RYK
|
receptor-like tyrosine kinase
|
|
S100A4
|
S100 calcium binding protein A4
|
|
SDC1
|
syndecan 1
|
|
SDC2
|
syndecan 2
|
|
SDC4
|
syndecan 4
|
|
SEMA3A
|
sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3A
|
|
SEMA3B
|
sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3B
|
|
SEMA3F
|
sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3F
|
|
SERPINB5
|
serpin peptidase inhibitor, clade B (ovalbumin), member 5
|
|
SGK223
|
homolog of rat pragma of Rnd2
|
|
SHH
|
sonic hedgehog
|
|
SKP2
|
S-phase kinase-associated protein 2, E3 ubiquitin protein ligase
|
|
SLC28A3
|
solute carrier family 28 (concentrative nucleoside transporter), member 3
|
|
SLC9A1
|
solute carrier family 9, subfamily A (NHE1, cation proton antiporter 1), member 1
|
|
SLIT2
|
slit homolog 2 (Drosophila)
|
|
SMAD2
|
SMAD family member 2
|
|
SMAD3
|
SMAD family member 3
|
|
SMO
|
smoothened, frizzled class receptor
|
|
SMPD2
|
sphingomyelin phosphodiesterase 2, neutral membrane (neutral sphingomyelinase)
|
|
SMURF1
|
SMAD specific E3 ubiquitin protein ligase 1
|
|
SNW1
|
SNW domain containing 1
|
|
SORT1
|
sortilin 1
|
|
SRC
|
SRC proto-oncogene, non-receptor tyrosine kinase
|
|
SRF
|
serum response factor (c-fos serum response element-binding transcription factor)
|
|
SRGAP1
|
SLIT-ROBO Rho GTPase activating protein 1
|
|
STARD13
|
StAR-related lipid transfer (START) domain containing 13
|
|
STAT6
|
signal transducer and activator of transcription 6, interleukin-4 induced
|
|
STIM1
|
stromal interaction molecule 1
|
|
STK11
|
serine/threonine kinase 11
|
|
SYK
|
spleen tyrosine kinase
|
|
SYNPO
|
synaptopodin
|
|
TAX1BP3
|
Tax1 (human T-cell leukemia virus type I) binding protein 3
|
|
TBC1D15
|
TBC1 domain family, member 15
|
|
TBXA2R
|
thromboxane A2 receptor
|
|
TEK
|
TEK tyrosine kinase, endothelial
|
|
TET2
|
tet methylcytosine dioxygenase 2
|
|
TGFB1
|
transforming growth factor, beta 1
|
|
TGFBR1
|
transforming growth factor, beta receptor 1
|
|
TGM2
|
transglutaminase 2
|
|
THSD1
|
thrombospondin, type I, domain containing 1
|
|
TIAM1
|
T-cell lymphoma invasion and metastasis 1
|
|
TLR2
|
toll-like receptor 2
|
|
TLR3
|
toll-like receptor 3
|
|
TNC
|
tenascin C
|
|
TNF
|
tumor necrosis factor
|
|
TNFRSF19
|
tumor necrosis factor receptor superfamily, member 19
|
|
TNFRSF1B
|
tumor necrosis factor receptor superfamily, member 1B
|
|
TP53
|
tumor protein p53
|
|
TPT1
|
tumor protein, translationally-controlled 1
|
|
TRPC6
|
transient receptor potential cation channel, subfamily C, member 6
|
|
TYK2
|
tyrosine kinase 2
|
|
UBXN11
|
UBX domain protein 11
|
|
VASP
|
vasodilator-stimulated phosphoprotein
|
|
VAV2
|
vav 2 guanine nucleotide exchange factor
|
|
VEGFA
|
vascular endothelial growth factor A
|
|
VEGFC
|
vascular endothelial growth factor C
|
|
VWF
|
von Willebrand factor
|
|
WNT5A
|
wingless-type MMTV integration site family, member 5A
|
|
WNT5B
|
wingless-type MMTV integration site family, member 5B
|
|
XIAP
|
X-linked inhibitor of apoptosis, E3 ubiquitin protein ligase
|
