rhoh Gene Set

Dataset GeneRIF Biological Term Annotations
Category structural or functional annotations
Type biological term
Description ras homolog family member H|The protein encoded by this gene is a member of the Ras superfamily of guanosine triphosphate (GTP)-metabolizing enzymes. The encoded protein is expressed in hematopoietic cells, where it functions as a negative regulator of cell growth and survival. This gene may be hypermutated or misexpressed in leukemias and lymphomas. Chromosomal translocations in non-Hodgkin's lymphoma occur between this locus and B-cell CLL/lymphoma 6 (BCL6) on chromosome 3, leading to the production of fusion transcripts. Alternative splicing in the 5' untranslated region results in multiple transcript variants that encode the same protein. [provided by RefSeq, May 2013] (NCBI Entrez Gene Database, 399)
Similar Terms
Downloads & Tools

Genes

4 genes co-occuring with the biological term rhoh in literature-supported statements describing functions of genes from the GeneRIF Biological Term Annotations dataset.

Symbol Name
IL3 interleukin 3
JUND jun D proto-oncogene
RAC2 ras-related C3 botulinum toxin substrate 2 (rho family, small GTP binding protein Rac2)
RHOH ras homolog family member H