ribostamycin-2705 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

197 genes differentially expressed following the ribostamycin-2705 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ABCB4 ATP-binding cassette, sub-family B (MDR/TAP), member 4
ABCB6 ATP-binding cassette, sub-family B (MDR/TAP), member 6 (Langereis blood group)
ABCG4 ATP-binding cassette, sub-family G (WHITE), member 4
ADORA1 adenosine A1 receptor
ARSD arylsulfatase D
ATP10A ATPase, class V, type 10A
BIRC7 baculoviral IAP repeat containing 7
BLK BLK proto-oncogene, Src family tyrosine kinase
C14ORF1 chromosome 14 open reading frame 1
CADM4 cell adhesion molecule 4
CCDC85B coiled-coil domain containing 85B
CEACAM3 carcinoembryonic antigen-related cell adhesion molecule 3
CELA2A chymotrypsin-like elastase family, member 2A
CHRNB2 cholinergic receptor, nicotinic, beta 2 (neuronal)
CLMN calmin (calponin-like, transmembrane)
CNTNAP2 contactin associated protein-like 2
COL4A5 collagen, type IV, alpha 5
COL6A1 collagen, type VI, alpha 1
CPE carboxypeptidase E
CXCR3 chemokine (C-X-C motif) receptor 3
DCN decorin
DDX28 DEAD (Asp-Glu-Ala-Asp) box polypeptide 28
DES desmin
DMP1 dentin matrix acidic phosphoprotein 1
DNAH17 dynein, axonemal, heavy chain 17
FAM149B1 family with sequence similarity 149, member B1
FBP1 fructose-1,6-bisphosphatase 1
FPR3 formyl peptide receptor 3
GDPD2 glycerophosphodiester phosphodiesterase domain containing 2
GJA8 gap junction protein, alpha 8, 50kDa
GLS glutaminase
GPR132 G protein-coupled receptor 132
GSTA3 glutathione S-transferase alpha 3
HLA-DPA1 major histocompatibility complex, class II, DP alpha 1
HNF1A HNF1 homeobox A
HRG histidine-rich glycoprotein
HTR2B 5-hydroxytryptamine (serotonin) receptor 2B, G protein-coupled
IGFBP5 insulin-like growth factor binding protein 5
IGHA1 immunoglobulin heavy constant alpha 1
IGHM immunoglobulin heavy constant mu
KCNH6 potassium channel, voltage gated eag related subfamily H, member 6
KCNMA1 potassium channel, calcium activated large conductance subfamily M alpha, member 1
KSR1 kinase suppressor of ras 1
LHB luteinizing hormone beta polypeptide
LOX lysyl oxidase
LRRC48 leucine rich repeat containing 48
MAGEA5 melanoma antigen family A5
MAPT microtubule-associated protein tau
MARC1 mitochondrial amidoxime reducing component 1
MBNL1 muscleblind-like splicing regulator 1
ME3 malic enzyme 3, NADP(+)-dependent, mitochondrial
MPDZ multiple PDZ domain protein
MYF5 myogenic factor 5
MYL10 myosin, light chain 10, regulatory
MYL2 myosin, light chain 2, regulatory, cardiac, slow
MYLPF myosin light chain, phosphorylatable, fast skeletal muscle
NNMT nicotinamide N-methyltransferase
NR1I2 nuclear receptor subfamily 1, group I, member 2
NRL neural retina leucine zipper
OLFM1 olfactomedin 1
OR2B2 olfactory receptor, family 2, subfamily B, member 2
PAPPA2 pappalysin 2
PAX2 paired box 2
PCDHGA3 protocadherin gamma subfamily A, 3
PDCD6 programmed cell death 6
PDE4DIP phosphodiesterase 4D interacting protein
PGAM2 phosphoglycerate mutase 2 (muscle)
PLCB1 phospholipase C, beta 1 (phosphoinositide-specific)
PLXDC1 plexin domain containing 1
PPP2R2B protein phosphatase 2, regulatory subunit B, beta
PPP2R5B protein phosphatase 2, regulatory subunit B', beta
PRSS22 protease, serine, 22
PVT1 Pvt1 oncogene (non-protein coding)
RAB11B RAB11B, member RAS oncogene family
RAB27B RAB27B, member RAS oncogene family
RAI1 retinoic acid induced 1
RARRES3 retinoic acid receptor responder (tazarotene induced) 3
RASGRP2 RAS guanyl releasing protein 2 (calcium and DAG-regulated)
SIGLEC15 sialic acid binding Ig-like lectin 15
SIGLEC8 sialic acid binding Ig-like lectin 8
SIM2 single-minded family bHLH transcription factor 2
SLAMF1 signaling lymphocytic activation molecule family member 1
SLC17A6 solute carrier family 17 (vesicular glutamate transporter), member 6
SLC24A1 solute carrier family 24 (sodium/potassium/calcium exchanger), member 1
SLCO2A1 solute carrier organic anion transporter family, member 2A1
SLMO1 slowmo homolog 1 (Drosophila)
SNAP25 synaptosomal-associated protein, 25kDa
SORBS3 sorbin and SH3 domain containing 3
SORCS3 sortilin-related VPS10 domain containing receptor 3
SPN sialophorin
SULF1 sulfatase 1
SULT1A2 sulfotransferase family, cytosolic, 1A, phenol-preferring, member 2
TLX3 T-cell leukemia homeobox 3
TM4SF1 transmembrane 4 L six family member 1
TNFRSF11B tumor necrosis factor receptor superfamily, member 11b
TP53I11 tumor protein p53 inducible protein 11
TRAF1 TNF receptor-associated factor 1
UTP14A UTP14, U3 small nucleolar ribonucleoprotein, homolog A (yeast)
ZNF205 zinc finger protein 205

decreased expression

Symbol Name
ACOX2 acyl-CoA oxidase 2, branched chain
AMDHD2 amidohydrolase domain containing 2
ANKH ANKH inorganic pyrophosphate transport regulator
ATG9A autophagy related 9A
BATF basic leucine zipper transcription factor, ATF-like
C16ORF45 chromosome 16 open reading frame 45
C6ORF47 chromosome 6 open reading frame 47
CAMKMT calmodulin-lysine N-methyltransferase
CBX4 chromobox homolog 4
CCDC57 coiled-coil domain containing 57
CCDC85C coiled-coil domain containing 85C
CCL4 chemokine (C-C motif) ligand 4
CCT6B chaperonin containing TCP1, subunit 6B (zeta 2)
CD37 CD37 molecule
CD69 CD69 molecule
CDA cytidine deaminase
CES3 carboxylesterase 3
CHRNA5 cholinergic receptor, nicotinic, alpha 5 (neuronal)
CHST7 carbohydrate (N-acetylglucosamine 6-O) sulfotransferase 7
CLGN calmegin
CLIP2 CAP-GLY domain containing linker protein 2
COLQ collagen-like tail subunit (single strand of homotrimer) of asymmetric acetylcholinesterase
CSGALNACT1 chondroitin sulfate N-acetylgalactosaminyltransferase 1
CTSO cathepsin O
CXCL2 chemokine (C-X-C motif) ligand 2
DKK2 dickkopf WNT signaling pathway inhibitor 2
DNAJC1 DnaJ (Hsp40) homolog, subfamily C, member 1
DNM3 dynamin 3
DZANK1 double zinc ribbon and ankyrin repeat domains 1
EFNA3 ephrin-A3
EIF5A2 eukaryotic translation initiation factor 5A2
ERN2 endoplasmic reticulum to nucleus signaling 2
ETAA1 Ewing tumor-associated antigen 1
FAM120C family with sequence similarity 120C
FAM50B family with sequence similarity 50, member B
FLT4 fms-related tyrosine kinase 4
GCH1 GTP cyclohydrolase 1
GLCE glucuronic acid epimerase
GPALPP1 GPALPP motifs containing 1
GPR27 G protein-coupled receptor 27
GPR65 G protein-coupled receptor 65
GRPR gastrin-releasing peptide receptor
IDI2-AS1 IDI2 antisense RNA 1
IFNA14 interferon, alpha 14
INA internexin neuronal intermediate filament protein, alpha
IQSEC1 IQ motif and Sec7 domain 1
JUP junction plakoglobin
KCTD7 potassium channel tetramerization domain containing 7
LRP3 low density lipoprotein receptor-related protein 3
MAGEH1 melanoma antigen family H1
MILR1 mast cell immunoglobulin-like receptor 1
MKL2 MKL/myocardin-like 2
NBR2 neighbor of BRCA1 gene 2 (non-protein coding)
NINJ2 ninjurin 2
NME8 NME/NM23 family member 8
OLAH oleoyl-ACP hydrolase
OLR1 oxidized low density lipoprotein (lectin-like) receptor 1
OVGP1 oviductal glycoprotein 1, 120kDa
PARG poly (ADP-ribose) glycohydrolase
PDE6C phosphodiesterase 6C, cGMP-specific, cone, alpha prime
PENK proenkephalin
PEX13 peroxisomal biogenesis factor 13
PIGH phosphatidylinositol glycan anchor biosynthesis, class H
PIK3R2 phosphoinositide-3-kinase, regulatory subunit 2 (beta)
PIM2 Pim-2 proto-oncogene, serine/threonine kinase
PLD3 phospholipase D family, member 3
PODXL2 podocalyxin-like 2
PRF1 perforin 1 (pore forming protein)
QPCT glutaminyl-peptide cyclotransferase
RAB3IL1 RAB3A interacting protein (rabin3)-like 1
RAC3 ras-related C3 botulinum toxin substrate 3 (rho family, small GTP binding protein Rac3)
RHBDD3 rhomboid domain containing 3
RRAGB Ras-related GTP binding B
RUSC2 RUN and SH3 domain containing 2
SCG5 secretogranin V
SH2D4A SH2 domain containing 4A
SLC25A23 solute carrier family 25 (mitochondrial carrier; phosphate carrier), member 23
SLC35E3 solute carrier family 35, member E3
SLC38A6 solute carrier family 38, member 6
SLC3A1 solute carrier family 3 (amino acid transporter heavy chain), member 1
SLC7A9 solute carrier family 7 (amino acid transporter light chain, bo,+ system), member 9
SLC9A3R1 solute carrier family 9, subfamily A (NHE3, cation proton antiporter 3), member 3 regulator 1
SPINK2 serine peptidase inhibitor, Kazal type 2 (acrosin-trypsin inhibitor)
SRPX sushi-repeat containing protein, X-linked
SSBP3 single stranded DNA binding protein 3
TBX19 T-box 19
THAP7 THAP domain containing 7
TMBIM1 transmembrane BAX inhibitor motif containing 1
TMEM134 transmembrane protein 134
TSPAN13 tetraspanin 13
ULK1 unc-51 like autophagy activating kinase 1
VASH2 vasohibin 2
ZBTB25 zinc finger and BTB domain containing 25
ZNF177 zinc finger protein 177
ZNF219 zinc finger protein 219
ZNF329 zinc finger protein 329
ZNF668 zinc finger protein 668
ZNF76 zinc finger protein 76