ribostamycin-6765 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

198 genes differentially expressed following the ribostamycin-6765 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ADAM17 ADAM metallopeptidase domain 17
AKAP4 A kinase (PRKA) anchor protein 4
AKT3 v-akt murine thymoma viral oncogene homolog 3
ANP32A-IT1 ANP32A intronic transcript 1
ARTN artemin
BMP1 bone morphogenetic protein 1
C1QL1 complement component 1, q subcomponent-like 1
CACFD1 calcium channel flower domain containing 1
CALD1 caldesmon 1
CDC42EP2 CDC42 effector protein (Rho GTPase binding) 2
CFLAR CASP8 and FADD-like apoptosis regulator
CHKB choline kinase beta
CLCN7 chloride channel, voltage-sensitive 7
COL6A1 collagen, type VI, alpha 1
CTBP2 C-terminal binding protein 2
CYP3A4 cytochrome P450, family 3, subfamily A, polypeptide 4
DNAJB12 DnaJ (Hsp40) homolog, subfamily B, member 12
DUSP13 dual specificity phosphatase 13
DUSP6 dual specificity phosphatase 6
EGF epidermal growth factor
EGFL7 EGF-like-domain, multiple 7
EHD2 EH-domain containing 2
ENO2 enolase 2 (gamma, neuronal)
ETAA1 Ewing tumor-associated antigen 1
ETV6 ets variant 6
EXOSC2 exosome component 2
FLJ22184
FRAT2 frequently rearranged in advanced T-cell lymphomas 2
GALNT12 polypeptide N-acetylgalactosaminyltransferase 12
GK glycerol kinase
GOSR2 golgi SNAP receptor complex member 2
GPR15 G protein-coupled receptor 15
GPR157 G protein-coupled receptor 157
GPR85 G protein-coupled receptor 85
GSPT1 G1 to S phase transition 1
GUSBP3 glucuronidase, beta pseudogene 3
HMGA1 high mobility group AT-hook 1
HOXA4 homeobox A4
HOXC5 homeobox C5
HYAL3 hyaluronoglucosaminidase 3
IKBKE inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase epsilon
IL11 interleukin 11
IL1B interleukin 1, beta
ITGB3 integrin, beta 3 (platelet glycoprotein IIIa, antigen CD61)
JAK2 Janus kinase 2
JUN jun proto-oncogene
LEPR leptin receptor
LLPH LLP homolog, long-term synaptic facilitation (Aplysia)
LMF2 lipase maturation factor 2
MAPK7 mitogen-activated protein kinase 7
MAPK8 mitogen-activated protein kinase 8
MAST4 microtubule associated serine/threonine kinase family member 4
MBNL3 muscleblind-like splicing regulator 3
MMP16 matrix metallopeptidase 16 (membrane-inserted)
MYCN v-myc avian myelocytomatosis viral oncogene neuroblastoma derived homolog
NDRG2 NDRG family member 2
NFKB2 nuclear factor of kappa light polypeptide gene enhancer in B-cells 2 (p49/p100)
NLE1 notchless homolog 1 (Drosophila)
NPY1R neuropeptide Y receptor Y1
OR2F1 olfactory receptor, family 2, subfamily F, member 1 (gene/pseudogene)
PAIP2B poly(A) binding protein interacting protein 2B
PARG poly (ADP-ribose) glycohydrolase
PDE6B phosphodiesterase 6B, cGMP-specific, rod, beta
PER3 period circadian clock 3
PEX1 peroxisomal biogenesis factor 1
PHKA2 phosphorylase kinase, alpha 2 (liver)
PHLDA1 pleckstrin homology-like domain, family A, member 1
PI4K2A phosphatidylinositol 4-kinase type 2 alpha
PIGQ phosphatidylinositol glycan anchor biosynthesis, class Q
PKNOX2 PBX/knotted 1 homeobox 2
PLK3 polo-like kinase 3
PML promyelocytic leukemia
POFUT1 protein O-fucosyltransferase 1
POLR2A polymerase (RNA) II (DNA directed) polypeptide A, 220kDa
RAD51 RAD51 recombinase
RALGAPA1 Ral GTPase activating protein, alpha subunit 1 (catalytic)
RALGPS2 Ral GEF with PH domain and SH3 binding motif 2
RBM25 RNA binding motif protein 25
RECQL5 RecQ protein-like 5
SAYSD1 SAYSVFN motif domain containing 1
SECTM1 secreted and transmembrane 1
SERGEF secretion regulating guanine nucleotide exchange factor
SETD1B SET domain containing 1B
SFTPB surfactant protein B
SLC30A3 solute carrier family 30 (zinc transporter), member 3
SLC7A8 solute carrier family 7 (amino acid transporter light chain, L system), member 8
SRF serum response factor (c-fos serum response element-binding transcription factor)
STAT5B signal transducer and activator of transcription 5B
SYT12 synaptotagmin XII
TBC1D30 TBC1 domain family, member 30
TFPI tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor)
TTC38 tetratricopeptide repeat domain 38
TUBA3C tubulin, alpha 3c
UTP18 UTP18 small subunit (SSU) processome component homolog (yeast)
YTHDC2 YTH domain containing 2
ZNF277 zinc finger protein 277
ZNF34 zinc finger protein 34
ZNF350 zinc finger protein 350
ZNF37BP zinc finger protein 37B, pseudogene
ZNF552 zinc finger protein 552

decreased expression

Symbol Name
ABCA12 ATP-binding cassette, sub-family A (ABC1), member 12
ADGRG2 adhesion G protein-coupled receptor G2
ARID3B AT rich interactive domain 3B (BRIGHT-like)
ARRB1 arrestin, beta 1
B3GNT3 UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 3
C11ORF30 chromosome 11 open reading frame 30
CACNA2D2 calcium channel, voltage-dependent, alpha 2/delta subunit 2
CCDC85C coiled-coil domain containing 85C
CCDC88C coiled-coil domain containing 88C
CD3D CD3d molecule, delta (CD3-TCR complex)
CD82 CD82 molecule
CD83 CD83 molecule
CDK3 cyclin-dependent kinase 3
CES3 carboxylesterase 3
CGA glycoprotein hormones, alpha polypeptide
CHAC1 ChaC glutathione-specific gamma-glutamylcyclotransferase 1
CHST7 carbohydrate (N-acetylglucosamine 6-O) sulfotransferase 7
CLSPN claspin
CNPY3 canopy FGF signaling regulator 3
CORO7 coronin 7
CORT cortistatin
CRLF1 cytokine receptor-like factor 1
CST6 cystatin E/M
CTSC cathepsin C
CYP2B7P cytochrome P450, family 2, subfamily B, polypeptide 7, pseudogene
DAGLA diacylglycerol lipase, alpha
DNAL4 dynein, axonemal, light chain 4
EPB41L5 erythrocyte membrane protein band 4.1 like 5
F2R coagulation factor II (thrombin) receptor
FAM184A family with sequence similarity 184, member A
FAM63A family with sequence similarity 63, member A
FOXI1 forkhead box I1
FOXRED2 FAD-dependent oxidoreductase domain containing 2
FURIN furin (paired basic amino acid cleaving enzyme)
GAMT guanidinoacetate N-methyltransferase
GAS2 growth arrest-specific 2
GID4 GID complex subunit 4
HDAC7 histone deacetylase 7
HIRA histone cell cycle regulator
HIST1H2AJ histone cluster 1, H2aj
HIST1H2AK histone cluster 1, H2ak
HIST1H2BN histone cluster 1, H2bn
IDI2-AS1 IDI2 antisense RNA 1
IFI27 interferon, alpha-inducible protein 27
IFI6 interferon, alpha-inducible protein 6
IRF7 interferon regulatory factor 7
ITPKB inositol-trisphosphate 3-kinase B
JMJD4 jumonji domain containing 4
KPTN kaptin (actin binding protein)
LIME1 Lck interacting transmembrane adaptor 1
LOC202181 SUMO-interacting motifs containing 1 pseudogene
LOC730101 uncharacterized LOC730101
MAN2C1 mannosidase, alpha, class 2C, member 1
MED9 mediator complex subunit 9
METTL8 methyltransferase like 8
MFGE8 milk fat globule-EGF factor 8 protein
MTHFD2L methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 2-like
NCALD neurocalcin delta
NEAT1 nuclear paraspeckle assembly transcript 1 (non-protein coding)
NNAT neuronatin
NUP62CL nucleoporin 62kDa C-terminal like
OAS3 2'-5'-oligoadenylate synthetase 3, 100kDa
P3H1 prolyl 3-hydroxylase 1
PICK1 protein interacting with PRKCA 1
PLD2 phospholipase D2
PLEKHF1 pleckstrin homology domain containing, family F (with FYVE domain) member 1
PRICKLE3 prickle homolog 3 (Drosophila)
R3HCC1L R3H domain and coiled-coil containing 1-like
RAB17 RAB17, member RAS oncogene family
RCN1 reticulocalbin 1, EF-hand calcium binding domain
RHBG Rh family, B glycoprotein (gene/pseudogene)
RNF170 ring finger protein 170
SAMD9 sterile alpha motif domain containing 9
SCML2 sex comb on midleg-like 2 (Drosophila)
SDC3 syndecan 3
SEMA4D sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4D
SH2D3A SH2 domain containing 3A
SIGLEC15 sialic acid binding Ig-like lectin 15
SIRAL2 SIR2 antiphage like 2
SLC44A1 solute carrier family 44 (choline transporter), member 1
SLIT2 slit homolog 2 (Drosophila)
SMR3A submaxillary gland androgen regulated protein 3A
SOX12 SRY (sex determining region Y)-box 12
STAG3 stromal antigen 3
STARD5 StAR-related lipid transfer (START) domain containing 5
STMN3 stathmin-like 3
SULT2B1 sulfotransferase family, cytosolic, 2B, member 1
TMEM53 transmembrane protein 53
TRAIP TRAF interacting protein
TUBA4B tubulin, alpha 4b
USB1 U6 snRNA biogenesis 1
USP27X ubiquitin specific peptidase 27, X-linked
USP5 ubiquitin specific peptidase 5 (isopeptidase T)
VN1R1 vomeronasal 1 receptor 1
ZBTB22 zinc finger and BTB domain containing 22
ZFHX3 zinc finger homeobox 3
ZNF254 zinc finger protein 254
ZNF747 zinc finger protein 747