ribostamycin-7123 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

199 genes differentially expressed following the ribostamycin-7123 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
AAK1 AP2 associated kinase 1
ABCA7 ATP-binding cassette, sub-family A (ABC1), member 7
ACADSB acyl-CoA dehydrogenase, short/branched chain
ARG2 arginase 2
ARHGEF5 Rho guanine nucleotide exchange factor (GEF) 5
ARHGEF9 Cdc42 guanine nucleotide exchange factor (GEF) 9
ASF1A anti-silencing function 1A histone chaperone
ATP5SL ATP5S-like
BAZ1B bromodomain adjacent to zinc finger domain, 1B
BCAS4 breast carcinoma amplified sequence 4
BRD9 bromodomain containing 9
BRF1 BRF1, RNA polymerase III transcription initiation factor 90 kDa subunit
C9ORF114 chromosome 9 open reading frame 114
C9ORF156 chromosome 9 open reading frame 156
CDKN1C cyclin-dependent kinase inhibitor 1C (p57, Kip2)
CEMIP cell migration inducing protein, hyaluronan binding
CENPJ centromere protein J
CEP295 centrosomal protein 295kDa
CLEC2B C-type lectin domain family 2, member B
CNTNAP2 contactin associated protein-like 2
CORO2A coronin, actin binding protein, 2A
COX6B1 cytochrome c oxidase subunit VIb polypeptide 1 (ubiquitous)
DENND2A DENN/MADD domain containing 2A
DHRS9 dehydrogenase/reductase (SDR family) member 9
DNAJB2 DnaJ (Hsp40) homolog, subfamily B, member 2
DOHH deoxyhypusine hydroxylase/monooxygenase
DOLPP1 dolichyldiphosphatase 1
DUSP8 dual specificity phosphatase 8
EIF5A2 eukaryotic translation initiation factor 5A2
ESRRA estrogen-related receptor alpha
ETV1 ets variant 1
FAM105A family with sequence similarity 105, member A
FAM173A family with sequence similarity 173, member A
GAD1 glutamate decarboxylase 1 (brain, 67kDa)
GALT galactose-1-phosphate uridylyltransferase
GGA2 golgi-associated, gamma adaptin ear containing, ARF binding protein 2
GRK5 G protein-coupled receptor kinase 5
GTSE1 G-2 and S-phase expressed 1
H2AFX H2A histone family, member X
HAPLN1 hyaluronan and proteoglycan link protein 1
HEATR6 HEAT repeat containing 6
HIST1H2BO histone cluster 1, H2bo
HLX H2.0-like homeobox
HRASLS2 HRAS-like suppressor 2
HSDL2 hydroxysteroid dehydrogenase like 2
IER3IP1 immediate early response 3 interacting protein 1
IGSF3 immunoglobulin superfamily, member 3
IQCK IQ motif containing K
KIAA0922 KIAA0922
KRT34 keratin 34, type I
LRP2 low density lipoprotein receptor-related protein 2
LRRFIP1 leucine rich repeat (in FLII) interacting protein 1
MPP3 membrane protein, palmitoylated 3 (MAGUK p55 subfamily member 3)
MUC7 mucin 7, secreted
MXRA8 matrix-remodelling associated 8
MYB v-myb avian myeloblastosis viral oncogene homolog
NCAPH2 non-SMC condensin II complex, subunit H2
NEDD9 neural precursor cell expressed, developmentally down-regulated 9
NFKBIE nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, epsilon
NPR2 natriuretic peptide receptor 2
NRF1 nuclear respiratory factor 1
NSD1 nuclear receptor binding SET domain protein 1
OSBPL3 oxysterol binding protein-like 3
PCDH7 protocadherin 7
PDK3 pyruvate dehydrogenase kinase, isozyme 3
PEG3 paternally expressed 3
PGK1 phosphoglycerate kinase 1
PHLDB1 pleckstrin homology-like domain, family B, member 1
PIN1 peptidylprolyl cis/trans isomerase, NIMA-interacting 1
PLEKHO1 pleckstrin homology domain containing, family O member 1
PLIN2 perilipin 2
PPIL2 peptidylprolyl isomerase (cyclophilin)-like 2
PTPN18 protein tyrosine phosphatase, non-receptor type 18 (brain-derived)
RABEP2 rabaptin, RAB GTPase binding effector protein 2
RAPGEF5 Rap guanine nucleotide exchange factor (GEF) 5
RNF41 ring finger protein 41, E3 ubiquitin protein ligase
RTEL1 regulator of telomere elongation helicase 1
SESN1 sestrin 1
SLC12A4 solute carrier family 12 (potassium/chloride transporter), member 4
SLC19A1 solute carrier family 19 (folate transporter), member 1
SLC25A23 solute carrier family 25 (mitochondrial carrier; phosphate carrier), member 23
SPRYD7 SPRY domain containing 7
STAC SH3 and cysteine rich domain
STAG3 stromal antigen 3
STAM2 signal transducing adaptor molecule (SH3 domain and ITAM motif) 2
TH tyrosine hydroxylase
TK2 thymidine kinase 2, mitochondrial
TM6SF1 transmembrane 6 superfamily member 1
TNK1 tyrosine kinase, non-receptor, 1
TRIM21 tripartite motif containing 21
TTC12 tetratricopeptide repeat domain 12
UROD uroporphyrinogen decarboxylase
VAMP2 vesicle-associated membrane protein 2 (synaptobrevin 2)
VWA8 von Willebrand factor A domain containing 8
WSCD1 WSC domain containing 1
ZC3H12A zinc finger CCCH-type containing 12A
ZFPM2 zinc finger protein, FOG family member 2
ZNF174 zinc finger protein 174
ZNF767P zinc finger family member 767, pseudogene
ZNF839 zinc finger protein 839

decreased expression

Symbol Name
AMPD2 adenosine monophosphate deaminase 2
ANKFY1 ankyrin repeat and FYVE domain containing 1
ANKS1A ankyrin repeat and sterile alpha motif domain containing 1A
ARMC6 armadillo repeat containing 6
BAHD1 bromo adjacent homology domain containing 1
BAX BCL2-associated X protein
BGLAP bone gamma-carboxyglutamate (gla) protein
BRIX1 BRX1, biogenesis of ribosomes
C16ORF62 chromosome 16 open reading frame 62
CCDC47 coiled-coil domain containing 47
CCDC69 coiled-coil domain containing 69
CDKN1A cyclin-dependent kinase inhibitor 1A (p21, Cip1)
CHPF chondroitin polymerizing factor
COL18A1 collagen, type XVIII, alpha 1
CSK c-src tyrosine kinase
DAPP1 dual adaptor of phosphotyrosine and 3-phosphoinositides
DCLRE1A DNA cross-link repair 1A
DDIT3 DNA-damage-inducible transcript 3
FAM155A family with sequence similarity 155, member A
FAM160B2 family with sequence similarity 160, member B2
FARP1 FERM, RhoGEF (ARHGEF) and pleckstrin domain protein 1 (chondrocyte-derived)
FCHSD2 FCH and double SH3 domains 2
GNAZ guanine nucleotide binding protein (G protein), alpha z polypeptide
GPALPP1 GPALPP motifs containing 1
HIRA histone cell cycle regulator
HIVEP1 human immunodeficiency virus type I enhancer binding protein 1
HOMER1 homer scaffolding protein 1
INCENP inner centromere protein antigens 135/155kDa
JUP junction plakoglobin
KBTBD4 kelch repeat and BTB (POZ) domain containing 4
KIAA0430 KIAA0430
KIAA0513 KIAA0513
KIAA0556 KIAA0556
KIAA0894 KIAA0894 protein
KIAA1462 KIAA1462
KIFC1 kinesin family member C1
KLC2 kinesin light chain 2
LPAR6 lysophosphatidic acid receptor 6
LTBP2 latent transforming growth factor beta binding protein 2
LYPLA2P1 lysophospholipase II pseudogene 1
MAP6D1 MAP6 domain containing 1
MAPK3 mitogen-activated protein kinase 3
MEX3C mex-3 RNA binding family member C
MFSD12 major facilitator superfamily domain containing 12
MGC12488
MISP mitotic spindle positioning
MXD3 MAX dimerization protein 3
NCSTN nicastrin
NRSN2 neurensin 2
NXPE3 neurexophilin and PC-esterase domain family, member 3
OPA3 optic atrophy 3 (autosomal recessive, with chorea and spastic paraplegia)
PID1 phosphotyrosine interaction domain containing 1
PNRC1 proline-rich nuclear receptor coactivator 1
PPDPF pancreatic progenitor cell differentiation and proliferation factor
PTGFR prostaglandin F receptor (FP)
PYCRL pyrroline-5-carboxylate reductase-like
RAB3A RAB3A, member RAS oncogene family
RABGGTA Rab geranylgeranyltransferase, alpha subunit
RASSF8 Ras association (RalGDS/AF-6) domain family (N-terminal) member 8
REPIN1 replication initiator 1
RFNG RFNG O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase
RGS20 regulator of G-protein signaling 20
RIPPLY3 ripply transcriptional repressor 3
RNF123 ring finger protein 123
RPS6KA4 ribosomal protein S6 kinase, 90kDa, polypeptide 4
RRNAD1 ribosomal RNA adenine dimethylase domain containing 1
RSF1 remodeling and spacing factor 1
SCML2 sex comb on midleg-like 2 (Drosophila)
SCYL2 SCY1-like 2 (S. cerevisiae)
SDC3 syndecan 3
SIX1 SIX homeobox 1
SLC39A1 solute carrier family 39 (zinc transporter), member 1
SMG1 SMG1 phosphatidylinositol 3-kinase-related kinase
SNX16 sorting nexin 16
SPATA7 spermatogenesis associated 7
STK16 serine/threonine kinase 16
STX1A syntaxin 1A (brain)
TESK1 testis-specific kinase 1
THOC6 THO complex 6
TIMM50 translocase of inner mitochondrial membrane 50 homolog (S. cerevisiae)
TNKS2 tankyrase, TRF1-interacting ankyrin-related ADP-ribose polymerase 2
TRAF6 TNF receptor-associated factor 6, E3 ubiquitin protein ligase
TRMT13 tRNA methyltransferase 13 homolog (S. cerevisiae)
TRMU tRNA 5-methylaminomethyl-2-thiouridylate methyltransferase
TROAP trophinin associated protein
TRPM2 transient receptor potential cation channel, subfamily M, member 2
TUBA3C tubulin, alpha 3c
TULP4 tubby like protein 4
UBXN2B UBX domain protein 2B
ULK1 unc-51 like autophagy activating kinase 1
UNKL unkempt family zinc finger-like
WWC2 WW and C2 domain containing 2
ZBTB10 zinc finger and BTB domain containing 10
ZDHHC14 zinc finger, DHHC-type containing 14
ZFP36 ZFP36 ring finger protein
ZNF107 zinc finger protein 107
ZNF12 zinc finger protein 12
ZNF180 zinc finger protein 180
ZNF813 zinc finger protein 813