ribostamycin Gene Set

Dataset LINCS L1000 CMAP Chemical Perturbation Consensus Signatures
Category transcriptomics
Type small molecule perturbation
Description An amino cyclitol glycoside that is 4,6-diaminocyclohexane-1,2,3-triol having a 2,6-diamino-2,6-dideoxy-alpha-D-glucosyl residue attached at position 1 and a beta-D-ribosyl residue attached at position 2. It is an antibiotic produced by Streptomyces ribosidificus (formerly S. thermoflavus). (Chemical Entities of Biological Interest Ontology, CHEBI_45257)
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Genes

10 genes differentially expressed following the ribostamycin small molecule perturbation from the LINCS L1000 CMAP Chemical Perturbation Consensus Signatures dataset.

increased expression

Symbol Name Standardized Value
CASK calcium/calmodulin-dependent serine protein kinase (MAGUK family) 3.63923
XIC X chromosome inactivation center 3.53842
SYNGR3 synaptogyrin 3 3.37137
MYL7 myosin, light chain 7, regulatory 3.36221
FABP3 fatty acid binding protein 3, muscle and heart 3.22229
CDC42 cell division cycle 42 3.15581

decreased expression

Symbol Name Standardized Value
MNAT1 MNAT CDK-activating kinase assembly factor 1 -3.68644
SH2D3C SH2 domain containing 3C -3.14132
ZFY zinc finger protein, Y-linked -3.02943
ULK4 unc-51 like kinase 4 -3.0024