ricinine-5725 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

200 genes differentially expressed following the ricinine-5725 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
AAGAB alpha- and gamma-adaptin binding protein
ABCG1 ATP-binding cassette, sub-family G (WHITE), member 1
ABHD8 abhydrolase domain containing 8
ACTA1 actin, alpha 1, skeletal muscle
ACVR1B activin A receptor, type IB
AKAP8L A kinase (PRKA) anchor protein 8-like
ANGPTL2 angiopoietin-like 2
APC adenomatous polyposis coli
ASTN1 astrotactin 1
ATF7IP activating transcription factor 7 interacting protein
BAGE B melanoma antigen
C14ORF93 chromosome 14 open reading frame 93
C2CD2L C2CD2-like
C7ORF69 chromosome 7 open reading frame 69
CASP10 caspase 10, apoptosis-related cysteine peptidase
CCL27 chemokine (C-C motif) ligand 27
CCNK cyclin K
CD1A CD1a molecule
CDC25C cell division cycle 25C
CFTR cystic fibrosis transmembrane conductance regulator (ATP-binding cassette sub-family C, member 7)
CHRNA9 cholinergic receptor, nicotinic, alpha 9 (neuronal)
CLTC clathrin, heavy chain (Hc)
COL10A1 collagen, type X, alpha 1
CORO1A coronin, actin binding protein, 1A
CPB2 carboxypeptidase B2 (plasma)
CST4 cystatin S
CYP1A1 cytochrome P450, family 1, subfamily A, polypeptide 1
CYP1B1 cytochrome P450, family 1, subfamily B, polypeptide 1
CYP2A6 cytochrome P450, family 2, subfamily A, polypeptide 6
DCAKD dephospho-CoA kinase domain containing
DENND2A DENN/MADD domain containing 2A
DMC1 DNA meiotic recombinase 1
DZIP1 DAZ interacting zinc finger protein 1
ECE1 endothelin converting enzyme 1
EDA ectodysplasin A
FGFR2 fibroblast growth factor receptor 2
GOLGA8A golgin A8 family, member A
GPM6A glycoprotein M6A
GPR68 G protein-coupled receptor 68
GRM7 glutamate receptor, metabotropic 7
GRTP1 growth hormone regulated TBC protein 1
GSTA3 glutathione S-transferase alpha 3
H2AFJ H2A histone family, member J
HHLA1 HERV-H LTR-associating 1
HIST1H4F histone cluster 1, H4f
HNRNPA3P1 heterogeneous nuclear ribonucleoprotein A3 pseudogene 1
HTR1B 5-hydroxytryptamine (serotonin) receptor 1B, G protein-coupled
HUS1 HUS1 checkpoint homolog (S. pombe)
IFT38 intraflagellar transport 38
ING4 inhibitor of growth family, member 4
KDM8 lysine (K)-specific demethylase 8
KIAA1456 KIAA1456
KLF4 Kruppel-like factor 4 (gut)
KLRC3 killer cell lectin-like receptor subfamily C, member 3
KRT34 keratin 34, type I
LDHC lactate dehydrogenase C
MAPK8IP1 mitogen-activated protein kinase 8 interacting protein 1
MBD2 methyl-CpG binding domain protein 2
MCOLN3 mucolipin 3
METTL7A methyltransferase like 7A
MINK1 misshapen-like kinase 1
MLLT3 myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 3
MRPL20 mitochondrial ribosomal protein L20
MTMR8 myotubularin related protein 8
N4BP1 NEDD4 binding protein 1
NDUFA5 NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 5
NEK3 NIMA-related kinase 3
NPC1 Niemann-Pick disease, type C1
NPHP1 nephronophthisis 1 (juvenile)
NPIPB3 nuclear pore complex interacting protein family, member B3
NPTX1 neuronal pentraxin I
NR4A2 nuclear receptor subfamily 4, group A, member 2
PAFAH2 platelet-activating factor acetylhydrolase 2, 40kDa
PDE12 phosphodiesterase 12
PDE4D phosphodiesterase 4D, cAMP-specific
PIGQ phosphatidylinositol glycan anchor biosynthesis, class Q
RABEP1 rabaptin, RAB GTPase binding effector protein 1
RASSF4 Ras association (RalGDS/AF-6) domain family member 4
RB1 retinoblastoma 1
RBM12B RNA binding motif protein 12B
RETN resistin
RQCD1 RCD1 required for cell differentiation1 homolog (S. pombe)
RRN3P1 RNA polymerase I transcription factor homolog (S. cerevisiae) pseudogene 1
SEMA3B sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3B
SLC2A1 solute carrier family 2 (facilitated glucose transporter), member 1
SP1 Sp1 transcription factor
SRPK2 SRSF protein kinase 2
TADA3 transcriptional adaptor 3
TBX2 T-box 2
TMPRSS2 transmembrane protease, serine 2
TNKS tankyrase, TRF1-interacting ankyrin-related ADP-ribose polymerase
TTC39A tetratricopeptide repeat domain 39A
VWA5A von Willebrand factor A domain containing 5A
XDH xanthine dehydrogenase
YIPF2 Yip1 domain family, member 2
ZFP36L2 ZFP36 ring finger protein-like 2
ZFP64 ZFP64 zinc finger protein
ZNF639 zinc finger protein 639
ZNF702P zinc finger protein 702, pseudogene
ZSCAN18 zinc finger and SCAN domain containing 18

decreased expression

Symbol Name
ABCA7 ATP-binding cassette, sub-family A (ABC1), member 7
ACTR3B ARP3 actin-related protein 3 homolog B (yeast)
ADTRP androgen-dependent TFPI-regulating protein
AFAP1 actin filament associated protein 1
AMDHD2 amidohydrolase domain containing 2
ANKRD36 ankyrin repeat domain 36
B3GALT4 UDP-Gal:betaGlcNAc beta 1,3-galactosyltransferase, polypeptide 4
C16ORF59 chromosome 16 open reading frame 59
C17ORF53 chromosome 17 open reading frame 53
C22ORF29 chromosome 22 open reading frame 29
CA8 carbonic anhydrase VIII
CBX4 chromobox homolog 4
CCDC186 coiled-coil domain containing 186
CCNJL cyclin J-like
CCT6B chaperonin containing TCP1, subunit 6B (zeta 2)
CDK3 cyclin-dependent kinase 3
CDKN1A cyclin-dependent kinase inhibitor 1A (p21, Cip1)
CHRNA10 cholinergic receptor, nicotinic, alpha 10 (neuronal)
CHST8 carbohydrate (N-acetylgalactosamine 4-0) sulfotransferase 8
CIDEC cell death-inducing DFFA-like effector c
CINP cyclin-dependent kinase 2 interacting protein
CISH cytokine inducible SH2-containing protein
CLN6 ceroid-lipofuscinosis, neuronal 6, late infantile, variant
CNGB3 cyclic nucleotide gated channel beta 3
CORT cortistatin
CREB5 cAMP responsive element binding protein 5
CYP17A1 cytochrome P450, family 17, subfamily A, polypeptide 1
DYRK3 dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 3
EFNB1 ephrin-B1
ESM1 endothelial cell-specific molecule 1
FARP2 FERM, RhoGEF and pleckstrin domain protein 2
FBXO2 F-box protein 2
FGL1 fibrinogen-like 1
FUZ fuzzy planar cell polarity protein
GFPT2 glutamine-fructose-6-phosphate transaminase 2
GLB1L galactosidase, beta 1-like
GLCE glucuronic acid epimerase
GNB1L guanine nucleotide binding protein (G protein), beta polypeptide 1-like
GNG3 guanine nucleotide binding protein (G protein), gamma 3
GPR3 G protein-coupled receptor 3
GPX2 glutathione peroxidase 2
GRAMD1C GRAM domain containing 1C
GTF2A1 general transcription factor IIA, 1, 19/37kDa
HERC5 HECT and RLD domain containing E3 ubiquitin protein ligase 5
HIST1H2BJ histone cluster 1, H2bj
HIST1H2BM histone cluster 1, H2bm
HOOK1 hook microtubule-tethering protein 1
HSD17B8 hydroxysteroid (17-beta) dehydrogenase 8
KIAA0556 KIAA0556
KLC2 kinesin light chain 2
KLF3 Kruppel-like factor 3 (basic)
KRT31 keratin 31, type I
LIFR leukemia inhibitory factor receptor alpha
LIPG lipase, endothelial
LPAR3 lysophosphatidic acid receptor 3
LRFN4 leucine rich repeat and fibronectin type III domain containing 4
MAGEB2 melanoma antigen family B2
MAGEF1 melanoma antigen family F1
MAGEH1 melanoma antigen family H1
MILR1 mast cell immunoglobulin-like receptor 1
MTA2 metastasis associated 1 family, member 2
MVD mevalonate (diphospho) decarboxylase
NOD1 nucleotide-binding oligomerization domain containing 1
NOTCH1 notch 1
NPM3 nucleophosmin/nucleoplasmin 3
OLFML2A olfactomedin-like 2A
OTUD3 OTU deubiquitinase 3
PARD6A par-6 family cell polarity regulator alpha
PCDHGB5 protocadherin gamma subfamily B, 5
PLD3 phospholipase D family, member 3
PMPCA peptidase (mitochondrial processing) alpha
PPP2R3B protein phosphatase 2, regulatory subunit B'', beta
RAB3IL1 RAB3A interacting protein (rabin3)-like 1
RAC3 ras-related C3 botulinum toxin substrate 3 (rho family, small GTP binding protein Rac3)
RAD54L2 RAD54-like 2 (S. cerevisiae)
RNF122 ring finger protein 122
RNF125 ring finger protein 125, E3 ubiquitin protein ligase
SETBP1 SET binding protein 1
SH3TC2 SH3 domain and tetratricopeptide repeats 2
SHPK sedoheptulokinase
SLC12A8 solute carrier family 12, member 8
SLC46A3 solute carrier family 46, member 3
STK16 serine/threonine kinase 16
SULT4A1 sulfotransferase family 4A, member 1
TCEAL2 transcription elongation factor A (SII)-like 2
TENM1 teneurin transmembrane protein 1
TFF2 trefoil factor 2
TINAGL1 tubulointerstitial nephritis antigen-like 1
TMEM57 transmembrane protein 57
TRAF2 TNF receptor-associated factor 2
TRAPPC6A trafficking protein particle complex 6A
TRPC4AP transient receptor potential cation channel, subfamily C, member 4 associated protein
TUBA3C tubulin, alpha 3c
TUBG2 tubulin, gamma 2
UGT8 UDP glycosyltransferase 8
VN1R1 vomeronasal 1 receptor 1
VWA1 von Willebrand factor A domain containing 1
ZFHX2 zinc finger homeobox 2
ZNF137P zinc finger protein 137, pseudogene
ZNF629 zinc finger protein 629