rickets Gene Set

Dataset DISEASES Text-mining Gene-Disease Association Evidence Scores
Category disease or phenotype associations
Type disease
Description A bone remodeling disease that has_material_basis_in a vitamin D deficiency in children which results_in softening and deformity located_in bone. (Experimental Factor Ontology, EFO_0005583)
Similar Terms
Downloads & Tools

Genes

110 genes co-occuring with the disease rickets in abstracts of biomedical publications from the DISEASES Text-mining Gene-Disease Assocation Evidence Scores dataset.

Symbol Name Standardized Value
CYP27B1 cytochrome P450, family 27, subfamily B, polypeptide 1 2.4124
PHEX phosphate regulating endopeptidase homolog, X-linked 2.35149
FGF23 fibroblast growth factor 23 2.28421
VDR vitamin D (1,25- dihydroxyvitamin D3) receptor 2.26692
ALPL alkaline phosphatase, liver/bone/kidney 2.25054
ALPPL2 alkaline phosphatase, placental-like 2 2.23406
ALPP alkaline phosphatase, placental 2.23353
PTH parathyroid hormone 2.13567
SLC34A3 solute carrier family 34 (type II sodium/phosphate cotransporter), member 3 1.95065
CLCN5 chloride channel, voltage-sensitive 5 1.73413
EMP1 epithelial membrane protein 1 1.53084
CYP2R1 cytochrome P450, family 2, subfamily R, polypeptide 1 1.47725
MEPE matrix extracellular phosphoglycoprotein 1.44474
SPTA1 spectrin, alpha, erythrocytic 1 1.37905
HEBP1 heme binding protein 1 1.27083
BGLAP bone gamma-carboxyglutamate (gla) protein 1.19704
CYP24A1 cytochrome P450, family 24, subfamily A, polypeptide 1 1.18281
FAH fumarylacetoacetate hydrolase (fumarylacetoacetase) 1.18066
S100G S100 calcium binding protein G 1.17937
KL klotho 1.17378
DMP1 dentin matrix acidic phosphoprotein 1 1.15283
NADSYN1 NAD synthetase 1 1.13924
C10ORF88 chromosome 10 open reading frame 88 1.10678
SLC34A1 solute carrier family 34 (type II sodium/phosphate cotransporter), member 1 1.1051
TRPV5 transient receptor potential cation channel, subfamily V, member 5 1.09251
TRPV6 transient receptor potential cation channel, subfamily V, member 6 1.04588
GC group-specific component (vitamin D binding protein) 1.0265
OCRL oculocerebrorenal syndrome of Lowe 1.0168
ENPP1 ectonucleotide pyrophosphatase/phosphodiesterase 1 0.99233
MED1 mediator complex subunit 1 0.937459
FGF1 fibroblast growth factor 1 (acidic) 0.91308
HACD3 3-hydroxyacyl-CoA dehydratase 3 0.897461
FAM20C family with sequence similarity 20, member C 0.89541
CALB1 calbindin 1, 28kDa 0.890488
ACYP1 acylphosphatase 1, erythrocyte (common) type 0.790081
CALCA calcitonin-related polypeptide alpha 0.788033
SKA1 spindle and kinetochore associated complex subunit 1 0.779023
SLC9C1 solute carrier family 9, subfamily C (Na+-transporting carboxylic acid decarboxylase), member 1 0.760231
GNPTAB N-acetylglucosamine-1-phosphate transferase, alpha and beta subunits 0.745578
CASR calcium-sensing receptor 0.735838
SLC2A2 solute carrier family 2 (facilitated glucose transporter), member 2 0.725311
ACYP2 acylphosphatase 2, muscle type 0.690293
MGAM maltase-glucoamylase 0.654067
KHDRBS3 KH domain containing, RNA binding, signal transduction associated 3 0.650903
CABP1 calcium binding protein 1 0.648533
SDF4 stromal cell derived factor 4 0.620617
ATP6V0A2 ATPase, H+ transporting, lysosomal V0 subunit a2 0.615138
SLC9B2 solute carrier family 9, subfamily B (NHA2, cation proton antiporter 2), member 2 0.597571
MED4 mediator complex subunit 4 0.592506
CLDN16 claudin 16 0.580439
HSD3B7 hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 7 0.546644
CFAP20 cilia and flagella associated protein 20 0.525746
ACADSB acyl-CoA dehydrogenase, short/branched chain 0.513417
LIN37 lin-37 DREAM MuvB core complex component 0.495029
ATP6V1B1 ATPase, H+ transporting, lysosomal 56/58kDa, V1 subunit B1 0.483604
CKAP2 cytoskeleton associated protein 2 0.478289
TRPM6 transient receptor potential cation channel, subfamily M, member 6 0.467306
ACPP acid phosphatase, prostate 0.461639
AMELY amelogenin, Y-linked 0.449571
SOST sclerostin 0.435651
KCNJ1 potassium channel, inwardly rectifying subfamily J, member 1 0.433772
CAPNS1 calpain, small subunit 1 0.42289
AMELX amelogenin, X-linked 0.418394
FDX1 ferredoxin 1 0.412779
BSND barttin CLCNK-type chloride channel accessory beta subunit 0.398962
NANS N-acetylneuraminic acid synthase 0.397471
CLCN3 chloride channel, voltage-sensitive 3 0.392257
PHKG2 phosphorylase kinase, gamma 2 (testis) 0.371477
PHKB phosphorylase kinase, beta 0.36741
CFL1 cofilin 1 (non-muscle) 0.362609
SOSTDC1 sclerostin domain containing 1 0.352659
TPSG1 tryptase gamma 1 0.319363
SPP1 secreted phosphoprotein 1 0.307395
DSPP dentin sialophosphoprotein 0.305587
PTHLH parathyroid hormone-like hormone 0.304503
ALB albumin 0.302698
USO1 USO1 vesicle transport factor 0.300533
EDARADD EDAR-associated death domain 0.299812
CPS1 carbamoyl-phosphate synthase 1, mitochondrial 0.299452
CTNS cystinosin, lysosomal cystine transporter 0.299452
IGF1 insulin-like growth factor 1 (somatomedin C) 0.29118
CP ceruloplasmin (ferroxidase) 0.289386
CLCNKB chloride channel, voltage-sensitive Kb 0.286519
FDXR ferredoxin reductase 0.24996
SLC20A2 solute carrier family 20 (phosphate transporter), member 2 0.244345
FRZB frizzled-related protein 0.244345
KNTC1 kinetochore associated 1 0.240847
MSX2 msh homeobox 2 0.234573
TRPV4 transient receptor potential cation channel, subfamily V, member 4 0.227988
LOR loricrin 0.224884
PHKA2 phosphorylase kinase, alpha 2 (liver) 0.22145
DHCR7 7-dehydrocholesterol reductase 0.213959
MME membrane metallo-endopeptidase 0.213283
TRPM3 transient receptor potential cation channel, subfamily M, member 3 0.213283
SMS spermine synthase 0.208245
ATP6V0A4 ATPase, H+ transporting, lysosomal V0 subunit a4 0.20658
FGFR1 fibroblast growth factor receptor 1 0.204593
CTSK cathepsin K 0.196459
HPR haptoglobin-related protein 0.194548
AMBN ameloblastin (enamel matrix protein) 0.189551
GCM2 glial cells missing homolog 2 (Drosophila) 0.188632
IGFBP3 insulin-like growth factor binding protein 3 0.18472
RARG retinoic acid receptor, gamma 0.176485
GSAP gamma-secretase activating protein 0.172291
SLC25A18 solute carrier family 25 (glutamate carrier), member 18 0.169812
CAMP cathelicidin antimicrobial peptide 0.169571
SOX5 SRY (sex determining region Y)-box 5 0.168854
FGF19 fibroblast growth factor 19 0.160203
ZP3 zona pellucida glycoprotein 3 (sperm receptor) 0.159838
IGFBP4 insulin-like growth factor binding protein 4 0.157929