Dataset | CMAP Signatures of Differentially Expressed Genes for Small Molecules |
Category | transcriptomics |
Type | small molecule perturbation |
Description | small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis) |
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197 genes differentially expressed following the rifabutin-4349 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
Symbol | Name |
---|---|
AAMDC | adipogenesis associated, Mth938 domain containing |
ACSM3 | acyl-CoA synthetase medium-chain family member 3 |
ADAM19 | ADAM metallopeptidase domain 19 |
ADD3 | adducin 3 (gamma) |
AHNAK2 | AHNAK nucleoprotein 2 |
ANG | angiogenin, ribonuclease, RNase A family, 5 |
ARMCX2 | armadillo repeat containing, X-linked 2 |
ASAP3 | ArfGAP with SH3 domain, ankyrin repeat and PH domain 3 |
ATXN7L1 | ataxin 7-like 1 |
BTN2A2 | butyrophilin, subfamily 2, member A2 |
CCDC88A | coiled-coil domain containing 88A |
CEP112 | centrosomal protein 112kDa |
CITED1 | Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 1 |
CLGN | calmegin |
CSRP2 | cysteine and glycine-rich protein 2 |
CXCR4 | chemokine (C-X-C motif) receptor 4 |
CYLD | cylindromatosis (turban tumor syndrome) |
CYP26B1 | cytochrome P450, family 26, subfamily B, polypeptide 1 |
DHRS2 | dehydrogenase/reductase (SDR family) member 2 |
DNAJC12 | DnaJ (Hsp40) homolog, subfamily C, member 12 |
DPYSL4 | dihydropyrimidinase-like 4 |
EFNB3 | ephrin-B3 |
ELOVL4 | ELOVL fatty acid elongase 4 |
EMP1 | epithelial membrane protein 1 |
EPHB2 | EPH receptor B2 |
FAM105A | family with sequence similarity 105, member A |
FAM184A | family with sequence similarity 184, member A |
FAM49A | family with sequence similarity 49, member A |
FBXL7 | F-box and leucine-rich repeat protein 7 |
FRMD1 | FERM domain containing 1 |
FYN | FYN proto-oncogene, Src family tyrosine kinase |
GABARAPL1 | GABA(A) receptor-associated protein like 1 |
GK | glycerol kinase |
GLDC | glycine dehydrogenase (decarboxylating) |
GLRX | glutaredoxin (thioltransferase) |
GPRC5B | G protein-coupled receptor, class C, group 5, member B |
GRK5 | G protein-coupled receptor kinase 5 |
HEY1 | hes-related family bHLH transcription factor with YRPW motif 1 |
HOXA1 | homeobox A1 |
HPCAL4 | hippocalcin like 4 |
HSD17B11 | hydroxysteroid (17-beta) dehydrogenase 11 |
IFIT1 | interferon-induced protein with tetratricopeptide repeats 1 |
JAG1 | jagged 1 |
KIF21B | kinesin family member 21B |
KIF5C | kinesin family member 5C |
LINC00341 | long intergenic non-protein coding RNA 341 |
LRRC49 | leucine rich repeat containing 49 |
MAN1C1 | mannosidase, alpha, class 1C, member 1 |
MAOA | monoamine oxidase A |
MAP1B | microtubule-associated protein 1B |
METTL7A | methyltransferase like 7A |
MLLT11 | myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 11 |
MMD | monocyte to macrophage differentiation-associated |
MTSS1 | metastasis suppressor 1 |
MUC3B | mucin 3B, cell surface associated |
MXI1 | MAX interactor 1, dimerization protein |
N4BP2L1 | NEDD4 binding protein 2-like 1 |
NAP1L3 | nucleosome assembly protein 1-like 3 |
NME5 | NME/NM23 family member 5 |
NR4A3 | nuclear receptor subfamily 4, group A, member 3 |
PDGFC | platelet derived growth factor C |
PGAM2 | phosphoglycerate mutase 2 (muscle) |
PIK3CD | phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit delta |
PLCG2 | phospholipase C, gamma 2 (phosphatidylinositol-specific) |
PRPH | peripherin |
RAB29 | RAB29, member RAS oncogene family |
RAB8B | RAB8B, member RAS oncogene family |
RAI2 | retinoic acid induced 2 |
RASGRP2 | RAS guanyl releasing protein 2 (calcium and DAG-regulated) |
REEP1 | receptor accessory protein 1 |
RGCC | regulator of cell cycle |
RGL1 | ral guanine nucleotide dissociation stimulator-like 1 |
RNASE4 | ribonuclease, RNase A family, 4 |
RUNDC3B | RUN domain containing 3B |
SEPP1 | selenoprotein P, plasma, 1 |
SERPINB9 | serpin peptidase inhibitor, clade B (ovalbumin), member 9 |
SERPINI1 | serpin peptidase inhibitor, clade I (neuroserpin), member 1 |
SFXN3 | sideroflexin 3 |
SH3GL3 | SH3-domain GRB2-like 3 |
SIRT4 | sirtuin 4 |
SLC1A1 | solute carrier family 1 (neuronal/epithelial high affinity glutamate transporter, system Xag), member 1 |
SLC30A3 | solute carrier family 30 (zinc transporter), member 3 |
SMARCA1 | SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 1 |
ST3GAL5 | ST3 beta-galactoside alpha-2,3-sialyltransferase 5 |
STON1 | stonin 1 |
STYK1 | serine/threonine/tyrosine kinase 1 |
TBXA2R | thromboxane A2 receptor |
TFEB | transcription factor EB |
TNIK | TRAF2 and NCK interacting kinase |
TNS1 | tensin 1 |
TRIM2 | tripartite motif containing 2 |
TRIM36 | tripartite motif containing 36 |
VWA5A | von Willebrand factor A domain containing 5A |
ZBTB18 | zinc finger and BTB domain containing 18 |
ZCCHC24 | zinc finger, CCHC domain containing 24 |
ZMIZ2 | zinc finger, MIZ-type containing 2 |
ZNF204P | zinc finger protein 204, pseudogene |
Symbol | Name |
---|---|
ACIN1 | apoptotic chromatin condensation inducer 1 |
ACTL8 | actin-like 8 |
ADRA2C | adrenoceptor alpha 2C |
AES | amino-terminal enhancer of split |
ALG12 | ALG12, alpha-1,6-mannosyltransferase |
ARFGAP2 | ADP-ribosylation factor GTPase activating protein 2 |
ARHGEF1 | Rho guanine nucleotide exchange factor (GEF) 1 |
ARHGEF16 | Rho guanine nucleotide exchange factor (GEF) 16 |
ASPSCR1 | alveolar soft part sarcoma chromosome region, candidate 1 |
AXIN1 | axin 1 |
B9D2 | B9 protein domain 2 |
C14ORF79 | chromosome 14 open reading frame 79 |
C17ORF70 | chromosome 17 open reading frame 70 |
CAPN15 | calpain 15 |
CBFA2T3 | core-binding factor, runt domain, alpha subunit 2; translocated to, 3 |
CCDC94 | coiled-coil domain containing 94 |
CCND1 | cyclin D1 |
CDT1 | chromatin licensing and DNA replication factor 1 |
CISH | cytokine inducible SH2-containing protein |
CLN6 | ceroid-lipofuscinosis, neuronal 6, late infantile, variant |
CTSD | cathepsin D |
CXCL12 | chemokine (C-X-C motif) ligand 12 |
DDX51 | DEAD (Asp-Glu-Ala-Asp) box polypeptide 51 |
DUSP3 | dual specificity phosphatase 3 |
EFNA1 | ephrin-A1 |
ELMO3 | engulfment and cell motility 3 |
ERMAP | erythroblast membrane-associated protein (Scianna blood group) |
EVPL | envoplakin |
FAAH | fatty acid amide hydrolase |
GALK1 | galactokinase 1 |
GATA4 | GATA binding protein 4 |
GMEB1 | glucocorticoid modulatory element binding protein 1 |
GRWD1 | glutamate-rich WD repeat containing 1 |
GTF2I | general transcription factor IIi |
IGFBP4 | insulin-like growth factor binding protein 4 |
KCTD15 | potassium channel tetramerization domain containing 15 |
KEAP1 | kelch-like ECH-associated protein 1 |
KIAA0319L | KIAA0319-like |
LMNB2 | lamin B2 |
LPAR2 | lysophosphatidic acid receptor 2 |
LRFN4 | leucine rich repeat and fibronectin type III domain containing 4 |
LRRC41 | leucine rich repeat containing 41 |
LTBR | lymphotoxin beta receptor (TNFR superfamily, member 3) |
LY6D | lymphocyte antigen 6 complex, locus D |
LY6G5C | lymphocyte antigen 6 complex, locus G5C |
MARC1 | mitochondrial amidoxime reducing component 1 |
MC1R | melanocortin 1 receptor (alpha melanocyte stimulating hormone receptor) |
MCRS1 | microspherule protein 1 |
MEPCE | methylphosphate capping enzyme |
MLST8 | MTOR associated protein, LST8 homolog (S. cerevisiae) |
MPDU1 | mannose-P-dolichol utilization defect 1 |
MRM1 | mitochondrial rRNA methyltransferase 1 homolog (S. cerevisiae) |
MTG1 | mitochondrial ribosome-associated GTPase 1 |
NABP2 | nucleic acid binding protein 2 |
NIPAL2 | NIPA-like domain containing 2 |
NME6 | NME/NM23 nucleoside diphosphate kinase 6 |
OAS3 | 2'-5'-oligoadenylate synthetase 3, 100kDa |
OGDH | oxoglutarate (alpha-ketoglutarate) dehydrogenase (lipoamide) |
P2RX4 | purinergic receptor P2X, ligand gated ion channel, 4 |
PIEZO1 | piezo-type mechanosensitive ion channel component 1 |
PISD | phosphatidylserine decarboxylase |
POLD1 | polymerase (DNA directed), delta 1, catalytic subunit |
POLL | polymerase (DNA directed), lambda |
POLR3E | polymerase (RNA) III (DNA directed) polypeptide E (80kD) |
PP14571 | uncharacterized LOC100130449 |
PPAN | peter pan homolog (Drosophila) |
PPDPF | pancreatic progenitor cell differentiation and proliferation factor |
PRR4 | proline rich 4 (lacrimal) |
PSD4 | pleckstrin and Sec7 domain containing 4 |
PTGES2 | prostaglandin E synthase 2 |
RAB3D | RAB3D, member RAS oncogene family |
RIPK1 | receptor (TNFRSF)-interacting serine-threonine kinase 1 |
RNF208 | ring finger protein 208 |
RPAP1 | RNA polymerase II associated protein 1 |
SARS2 | seryl-tRNA synthetase 2, mitochondrial |
SERPINH1 | serpin peptidase inhibitor, clade H (heat shock protein 47), member 1, (collagen binding protein 1) |
SKI | SKI proto-oncogene |
SLC35C2 | solute carrier family 35 (GDP-fucose transporter), member C2 |
SLC39A1 | solute carrier family 39 (zinc transporter), member 1 |
SLC52A1 | solute carrier family 52 (riboflavin transporter), member 1 |
SLC9A2 | solute carrier family 9, subfamily A (NHE2, cation proton antiporter 2), member 2 |
SLMO1 | slowmo homolog 1 (Drosophila) |
SMG5 | SMG5 nonsense mediated mRNA decay factor |
SMG9 | SMG9 nonsense mediated mRNA decay factor |
SMPD2 | sphingomyelin phosphodiesterase 2, neutral membrane (neutral sphingomyelinase) |
SNHG3 | small nucleolar RNA host gene 3 |
STRN4 | striatin, calmodulin binding protein 4 |
TARBP2 | TAR (HIV-1) RNA binding protein 2 |
THBS3 | thrombospondin 3 |
TNFRSF12A | tumor necrosis factor receptor superfamily, member 12A |
TRIM25 | tripartite motif containing 25 |
UBTF | upstream binding transcription factor, RNA polymerase I |
UBXN8 | UBX domain protein 8 |
UTP20 | UTP20, small subunit (SSU) processome component, homolog (yeast) |
XRCC1 | X-ray repair complementing defective repair in Chinese hamster cells 1 |
ZBTB3 | zinc finger and BTB domain containing 3 |
ZNF286A | zinc finger protein 286A |
ZNF692 | zinc finger protein 692 |
ZNF747 | zinc finger protein 747 |
ZNF787 | zinc finger protein 787 |