rifampicin-2847 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

195 genes differentially expressed following the rifampicin-2847 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ABCB9 ATP-binding cassette, sub-family B (MDR/TAP), member 9
ACTG2 actin, gamma 2, smooth muscle, enteric
ACVR1B activin A receptor, type IB
ADRBK1 adrenergic, beta, receptor kinase 1
AKAP11 A kinase (PRKA) anchor protein 11
ARVCF armadillo repeat gene deleted in velocardiofacial syndrome
ATM ATM serine/threonine kinase
ATP6V1C1 ATPase, H+ transporting, lysosomal 42kDa, V1 subunit C1
ATPAF2 ATP synthase mitochondrial F1 complex assembly factor 2
C4ORF29 chromosome 4 open reading frame 29
CA5B carbonic anhydrase VB, mitochondrial
CASP2 caspase 2, apoptosis-related cysteine peptidase
CCBL1 cysteine conjugate-beta lyase, cytoplasmic
CCNK cyclin K
CDKAL1 CDK5 regulatory subunit associated protein 1-like 1
CFLAR CASP8 and FADD-like apoptosis regulator
CRKL v-crk avian sarcoma virus CT10 oncogene homolog-like
DCBLD2 discoidin, CUB and LCCL domain containing 2
DGKE diacylglycerol kinase, epsilon 64kDa
ECE1 endothelin converting enzyme 1
EPHB2 EPH receptor B2
FADS2 fatty acid desaturase 2
FRMD1 FERM domain containing 1
FUT2 fucosyltransferase 2 (secretor status included)
FUT6 fucosyltransferase 6 (alpha (1,3) fucosyltransferase)
GABBR2 gamma-aminobutyric acid (GABA) B receptor, 2
GINS4 GINS complex subunit 4 (Sld5 homolog)
GLS glutaminase
GNL3L guanine nucleotide binding protein-like 3 (nucleolar)-like
GPR137 G protein-coupled receptor 137
GUSBP3 glucuronidase, beta pseudogene 3
HIC2 hypermethylated in cancer 2
HIRA histone cell cycle regulator
HIST1H4E histone cluster 1, H4e
HLF hepatic leukemia factor
HMGCS1 3-hydroxy-3-methylglutaryl-CoA synthase 1 (soluble)
HNRNPUL2 heterogeneous nuclear ribonucleoprotein U-like 2
IL11 interleukin 11
IL6ST interleukin 6 signal transducer
IRS2 insulin receptor substrate 2
ITGA8 integrin, alpha 8
JAG1 jagged 1
KHK ketohexokinase (fructokinase)
LHX2 LIM homeobox 2
LOXL2 lysyl oxidase-like 2
LRRC1 leucine rich repeat containing 1
LYL1 lymphoblastic leukemia associated hematopoiesis regulator 1
MAGI1 membrane associated guanylate kinase, WW and PDZ domain containing 1
MAK male germ cell-associated kinase
MED18 mediator complex subunit 18
METTL7A methyltransferase like 7A
MITF microphthalmia-associated transcription factor
MYO1B myosin IB
NCOA2 nuclear receptor coactivator 2
NEAT1 nuclear paraspeckle assembly transcript 1 (non-protein coding)
NKX3-2 NK3 homeobox 2
NNAT neuronatin
NREP neuronal regeneration related protein
PCSK6 proprotein convertase subtilisin/kexin type 6
PIP5K1A phosphatidylinositol-4-phosphate 5-kinase, type I, alpha
PRICKLE3 prickle homolog 3 (Drosophila)
PTHLH parathyroid hormone-like hormone
RALGPS2 Ral GEF with PH domain and SH3 binding motif 2
RBPMS RNA binding protein with multiple splicing
RGS2 regulator of G-protein signaling 2
RHBDD3 rhomboid domain containing 3
RNFT1 ring finger protein, transmembrane 1
RREB1 ras responsive element binding protein 1
SAYSD1 SAYSVFN motif domain containing 1
SCAI suppressor of cancer cell invasion
SCHIP1 schwannomin interacting protein 1
SEMA4D sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4D
SLC24A1 solute carrier family 24 (sodium/potassium/calcium exchanger), member 1
SLC7A11 solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11
SLC9A1 solute carrier family 9, subfamily A (NHE1, cation proton antiporter 1), member 1
SOS2 son of sevenless homolog 2 (Drosophila)
SPATA5L1 spermatogenesis associated 5-like 1
SRRT serrate, RNA effector molecule
SUZ12P1 suppressor of zeste 12 homolog pseudogene 1
TEP1 telomerase-associated protein 1
TEX14 testis expressed 14
TRIM16 tripartite motif containing 16
TUBA3C tubulin, alpha 3c
UBE3A ubiquitin protein ligase E3A
VAMP1 vesicle-associated membrane protein 1 (synaptobrevin 1)
WDR55 WD repeat domain 55
WDR76 WD repeat domain 76
WDTC1 WD and tetratricopeptide repeats 1
WSB1 WD repeat and SOCS box containing 1
ZFP36L1 ZFP36 ring finger protein-like 1
ZFYVE9 zinc finger, FYVE domain containing 9
ZNF606 zinc finger protein 606
ZNF652 zinc finger protein 652
ZNF721 zinc finger protein 721
ZNF821 zinc finger protein 821
ZSCAN12 zinc finger and SCAN domain containing 12

decreased expression

Symbol Name
ACAD10 acyl-CoA dehydrogenase family, member 10
ACSL4 acyl-CoA synthetase long-chain family member 4
AP1G2 adaptor-related protein complex 1, gamma 2 subunit
APOD apolipoprotein D
ARC activity-regulated cytoskeleton-associated protein
ARHGEF17 Rho guanine nucleotide exchange factor (GEF) 17
BAG4 BCL2-associated athanogene 4
C11ORF80 chromosome 11 open reading frame 80
CA5BP1 carbonic anhydrase VB pseudogene 1
CALCOCO1 calcium binding and coiled-coil domain 1
CAPG capping protein (actin filament), gelsolin-like
CCDC88C coiled-coil domain containing 88C
CENPT centromere protein T
CHKB choline kinase beta
CHML choroideremia-like (Rab escort protein 2)
CUZD1 CUB and zona pellucida-like domains 1
DEAF1 DEAF1 transcription factor
DGCR11 DiGeorge syndrome critical region gene 11 (non-protein coding)
DMTN dematin actin binding protein
DNMT3A DNA (cytosine-5-)-methyltransferase 3 alpha
DUSP2 dual specificity phosphatase 2
FAM131A family with sequence similarity 131, member A
FAM169A family with sequence similarity 169, member A
FAM198B family with sequence similarity 198, member B
FAM46C family with sequence similarity 46, member C
GATA4 GATA binding protein 4
GBF1 golgi brefeldin A resistant guanine nucleotide exchange factor 1
GBP2 guanylate binding protein 2, interferon-inducible
GEMIN8 gem (nuclear organelle) associated protein 8
GIT1 G protein-coupled receptor kinase interacting ArfGAP 1
GNAZ guanine nucleotide binding protein (G protein), alpha z polypeptide
H2AFY2 H2A histone family, member Y2
HIST1H4D histone cluster 1, H4d
HLA-J major histocompatibility complex, class I, J (pseudogene)
HSPA1L heat shock 70kDa protein 1-like
INF2 inverted formin, FH2 and WH2 domain containing
INPP5J inositol polyphosphate-5-phosphatase J
IRAK4 interleukin-1 receptor-associated kinase 4
KLK5 kallikrein-related peptidase 5
LAMB3 laminin, beta 3
LHX6 LIM homeobox 6
LNPEP leucyl/cystinyl aminopeptidase
LRP5 low density lipoprotein receptor-related protein 5
LRRC61 leucine rich repeat containing 61
LYPD1 LY6/PLAUR domain containing 1
LZTS3 leucine zipper, putative tumor suppressor family member 3
MAMLD1 mastermind-like domain containing 1
MAN2C1 mannosidase, alpha, class 2C, member 1
MAP4K2 mitogen-activated protein kinase kinase kinase kinase 2
MAST3 microtubule associated serine/threonine kinase 3
MFSD11 major facilitator superfamily domain containing 11
MUM1 melanoma associated antigen (mutated) 1
MYL5 myosin, light chain 5, regulatory
NEK11 NIMA-related kinase 11
NRGN neurogranin (protein kinase C substrate, RC3)
ORAI3 ORAI calcium release-activated calcium modulator 3
PCDHB3 protocadherin beta 3
PIK3C2B phosphatidylinositol-4-phosphate 3-kinase, catalytic subunit type 2 beta
PIM2 Pim-2 proto-oncogene, serine/threonine kinase
PITX2 paired-like homeodomain 2
PKD2 polycystic kidney disease 2 (autosomal dominant)
PLCXD1 phosphatidylinositol-specific phospholipase C, X domain containing 1
PLEKHM2 pleckstrin homology domain containing, family M (with RUN domain) member 2
POLL polymerase (DNA directed), lambda
RASAL1 RAS protein activator like 1 (GAP1 like)
RNF2 ring finger protein 2
RPGR retinitis pigmentosa GTPase regulator
SASH1 SAM and SH3 domain containing 1
SCN1B sodium channel, voltage gated, type I beta subunit
SGTA small glutamine-rich tetratricopeptide repeat (TPR)-containing, alpha
SLC25A22 solute carrier family 25 (mitochondrial carrier: glutamate), member 22
SLC35F5 solute carrier family 35, member F5
SLC44A1 solute carrier family 44 (choline transporter), member 1
SLC8B1 solute carrier family 8 (sodium/lithium/calcium exchanger), member B1
SLC9A8 solute carrier family 9, subfamily A (NHE8, cation proton antiporter 8), member 8
SND1-IT1 SND1 intronic transcript 1
SPINK4 serine peptidase inhibitor, Kazal type 4
SPON2 spondin 2, extracellular matrix protein
SPSB1 splA/ryanodine receptor domain and SOCS box containing 1
SREBF1 sterol regulatory element binding transcription factor 1
STARD3 StAR-related lipid transfer (START) domain containing 3
STARD5 StAR-related lipid transfer (START) domain containing 5
SUPT5H suppressor of Ty 5 homolog (S. cerevisiae)
SUV39H1 suppressor of variegation 3-9 homolog 1 (Drosophila)
TARP TCR gamma alternate reading frame protein
TBX19 T-box 19
THRAP3 thyroid hormone receptor associated protein 3
TMC7 transmembrane channel-like 7
TMEM242 transmembrane protein 242
TOM1 target of myb1 (chicken)
TRPV1 transient receptor potential cation channel, subfamily V, member 1
TTLL1 tubulin tyrosine ligase-like family member 1
USP5 ubiquitin specific peptidase 5 (isopeptidase T)
ZDHHC14 zinc finger, DHHC-type containing 14
ZNF124 zinc finger protein 124
ZNF219 zinc finger protein 219
ZNF623 zinc finger protein 623
ZNF639 zinc finger protein 639
ZSCAN2 zinc finger and SCAN domain containing 2