rifampicin-4008 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

194 genes differentially expressed following the rifampicin-4008 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ABCB9 ATP-binding cassette, sub-family B (MDR/TAP), member 9
ABCC2 ATP-binding cassette, sub-family C (CFTR/MRP), member 2
ABCC9 ATP-binding cassette, sub-family C (CFTR/MRP), member 9
ADAM23 ADAM metallopeptidase domain 23
ADGRB2 adhesion G protein-coupled receptor B2
ALDH3B1 aldehyde dehydrogenase 3 family, member B1
ALOX5AP arachidonate 5-lipoxygenase-activating protein
ATG10 autophagy related 10
ATP8A2 ATPase, aminophospholipid transporter, class I, type 8A, member 2
BEND5 BEN domain containing 5
C14ORF79 chromosome 14 open reading frame 79
CACFD1 calcium channel flower domain containing 1
CADM3 cell adhesion molecule 3
CD6 CD6 molecule
CDC42 cell division cycle 42
CDKAL1 CDK5 regulatory subunit associated protein 1-like 1
CEACAM6 carcinoembryonic antigen-related cell adhesion molecule 6 (non-specific cross reacting antigen)
COX6A2 cytochrome c oxidase subunit VIa polypeptide 2
CT62 cancer/testis antigen 62
DBNDD1 dysbindin (dystrobrevin binding protein 1) domain containing 1
DNAJB12 DnaJ (Hsp40) homolog, subfamily B, member 12
DNASE1L3 deoxyribonuclease I-like 3
DNMT3A DNA (cytosine-5-)-methyltransferase 3 alpha
EML3 echinoderm microtubule associated protein like 3
EPHA5 EPH receptor A5
ESR1 estrogen receptor 1
ETV6 ets variant 6
FBXO22 F-box protein 22
FCN1 ficolin (collagen/fibrinogen domain containing) 1
FGF22 fibroblast growth factor 22
FLRT2 fibronectin leucine rich transmembrane protein 2
G3BP1 GTPase activating protein (SH3 domain) binding protein 1
GAS2 growth arrest-specific 2
GFI1 growth factor independent 1 transcription repressor
GLP1R glucagon-like peptide 1 receptor
GLYAT glycine-N-acyltransferase
GPM6B glycoprotein M6B
GPR15 G protein-coupled receptor 15
GSTCD glutathione S-transferase, C-terminal domain containing
GSTM5 glutathione S-transferase mu 5
GYPB glycophorin B (MNS blood group)
HBE1 hemoglobin, epsilon 1
HNF1B HNF1 homeobox B
HOXC11 homeobox C11
HOXC4 homeobox C4
ICA1 islet cell autoantigen 1, 69kDa
IL12A interleukin 12A
IL1RN interleukin 1 receptor antagonist
IL2RA interleukin 2 receptor, alpha
IRF8 interferon regulatory factor 8
LAT2 linker for activation of T cells family, member 2
LDB1 LIM domain binding 1
MAGEA12 melanoma antigen family A12
MAGEA6 melanoma antigen family A6
MAGI1 membrane associated guanylate kinase, WW and PDZ domain containing 1
MBTD1 mbt domain containing 1
MEP1B meprin A, beta
MERTK MER proto-oncogene, tyrosine kinase
MLLT10 myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 10
MMP16 matrix metallopeptidase 16 (membrane-inserted)
MTSS1 metastasis suppressor 1
MUC7 mucin 7, secreted
MYBPC3 myosin binding protein C, cardiac
NEURL1 neuralized E3 ubiquitin protein ligase 1
NLE1 notchless homolog 1 (Drosophila)
NOVA2 neuro-oncological ventral antigen 2
OAZ3 ornithine decarboxylase antizyme 3
PAPPA2 pappalysin 2
PDGFA platelet-derived growth factor alpha polypeptide
PHF20L1 PHD finger protein 20-like 1
PHLDB1 pleckstrin homology-like domain, family B, member 1
PI4K2A phosphatidylinositol 4-kinase type 2 alpha
PIK3IP1 phosphoinositide-3-kinase interacting protein 1
PLXND1 plexin D1
POU6F1 POU class 6 homeobox 1
PRKCI protein kinase C, iota
PRSS22 protease, serine, 22
PTN pleiotrophin
PTPRN2 protein tyrosine phosphatase, receptor type, N polypeptide 2
RGS4 regulator of G-protein signaling 4
SERPINB3 serpin peptidase inhibitor, clade B (ovalbumin), member 3
SIKE1 suppressor of IKBKE 1
SLC12A4 solute carrier family 12 (potassium/chloride transporter), member 4
SLC26A4 solute carrier family 26 (anion exchanger), member 4
SLC2A1 solute carrier family 2 (facilitated glucose transporter), member 1
SLMO1 slowmo homolog 1 (Drosophila)
SMAD4 SMAD family member 4
SPTAN1 spectrin, alpha, non-erythrocytic 1
STAG3L4 stromal antigen 3-like 4 (pseudogene)
THOP1 thimet oligopeptidase 1
TLK1 tousled-like kinase 1
TMEM206 transmembrane protein 206
TSPAN9 tetraspanin 9
TUBA3C tubulin, alpha 3c
ULBP1 UL16 binding protein 1
VCX2 variable charge, X-linked 2
WNT6 wingless-type MMTV integration site family, member 6
ZFPL1 zinc finger protein-like 1
ZNF518A zinc finger protein 518A

decreased expression

Symbol Name
ABL2 ABL proto-oncogene 2, non-receptor tyrosine kinase
ADGRF1 adhesion G protein-coupled receptor F1
AGMAT agmatine ureohydrolase (agmatinase)
ALOX12 arachidonate 12-lipoxygenase
ARHGAP24 Rho GTPase activating protein 24
BTF3P11 basic transcription factor 3 pseudogene 11
C14ORF105 chromosome 14 open reading frame 105
CA9 carbonic anhydrase IX
CEL carboxyl ester lipase
CINP cyclin-dependent kinase 2 interacting protein
CLN6 ceroid-lipofuscinosis, neuronal 6, late infantile, variant
CNGB3 cyclic nucleotide gated channel beta 3
CNR2 cannabinoid receptor 2 (macrophage)
CREB5 cAMP responsive element binding protein 5
CRYBA2 crystallin, beta A2
CUZD1 CUB and zona pellucida-like domains 1
CYB5R2 cytochrome b5 reductase 2
DAGLA diacylglycerol lipase, alpha
DBF4B DBF4 zinc finger B
DGCR11 DiGeorge syndrome critical region gene 11 (non-protein coding)
DNAH7 dynein, axonemal, heavy chain 7
EFNA3 ephrin-A3
ETS1 v-ets avian erythroblastosis virus E26 oncogene homolog 1
FA2H fatty acid 2-hydroxylase
FAM120C family with sequence similarity 120C
FGF23 fibroblast growth factor 23
FLT4 fms-related tyrosine kinase 4
FRMPD1 FERM and PDZ domain containing 1
FRS3 fibroblast growth factor receptor substrate 3
FSD1 fibronectin type III and SPRY domain containing 1
GALK1 galactokinase 1
GNA14 guanine nucleotide binding protein (G protein), alpha 14
GPC3 glypican 3
GUCY1A2 guanylate cyclase 1, soluble, alpha 2
HIST1H1D histone cluster 1, H1d
ITGAL integrin, alpha L (antigen CD11A (p180), lymphocyte function-associated antigen 1; alpha polypeptide)
ITGB7 integrin, beta 7
KIAA1456 KIAA1456
KLHL28 kelch-like family member 28
LIME1 Lck interacting transmembrane adaptor 1
LPAR4 lysophosphatidic acid receptor 4
LY6D lymphocyte antigen 6 complex, locus D
LYPD3 LY6/PLAUR domain containing 3
MAGEF1 melanoma antigen family F1
MAST3 microtubule associated serine/threonine kinase 3
MBL1P mannose-binding lectin (protein A) 1, pseudogene
MMP3 matrix metallopeptidase 3
MNMIP1 manchette microtubule inner protein 1
MTA2 metastasis associated 1 family, member 2
MYO1F myosin IF
NIPAL2 NIPA-like domain containing 2
NOL12 nucleolar protein 12
NPM3 nucleophosmin/nucleoplasmin 3
NTSR1 neurotensin receptor 1 (high affinity)
OBSCN obscurin, cytoskeletal calmodulin and titin-interacting RhoGEF
OR2F1 olfactory receptor, family 2, subfamily F, member 1 (gene/pseudogene)
PADI1 peptidyl arginine deiminase, type I
PDK4 pyruvate dehydrogenase kinase, isozyme 4
PIGZ phosphatidylinositol glycan anchor biosynthesis, class Z
PIP prolactin-induced protein
PLAG1 pleiomorphic adenoma gene 1
PLBD1 phospholipase B domain containing 1
PLD2 phospholipase D2
PRSS53 protease, serine, 53
PRSS8 protease, serine, 8
PSORS1C1 psoriasis susceptibility 1 candidate 1
RABGGTA Rab geranylgeranyltransferase, alpha subunit
REM1 RAS (RAD and GEM)-like GTP-binding 1
RNF126P1 ring finger protein 126 pseudogene 1
RNF19A ring finger protein 19A, RBR E3 ubiquitin protein ligase
RNPEPL1 arginyl aminopeptidase (aminopeptidase B)-like 1
RPRM reprimo, TP53 dependent G2 arrest mediator candidate
SCUBE3 signal peptide, CUB domain, EGF-like 3
SLAMF7 SLAM family member 7
SLC3A1 solute carrier family 3 (amino acid transporter heavy chain), member 1
SLC6A9 solute carrier family 6 (neurotransmitter transporter, glycine), member 9
SLC9A5 solute carrier family 9, subfamily A (NHE5, cation proton antiporter 5), member 5
SNRPN small nuclear ribonucleoprotein polypeptide N
SPATA1 spermatogenesis associated 1
SSTR4 somatostatin receptor 4
STAB2 stabilin 2
STEAP4 STEAP family member 4
STIM1 stromal interaction molecule 1
TBC1D8B TBC1 domain family, member 8B (with GRAM domain)
TCTN2 tectonic family member 2
TESPA1 thymocyte expressed, positive selection associated 1
TIGD6 tigger transposable element derived 6
TSKU tsukushi, small leucine rich proteoglycan
TUT1 terminal uridylyl transferase 1, U6 snRNA-specific
UBQLN4 ubiquilin 4
USP27X ubiquitin specific peptidase 27, X-linked
ZNF276 zinc finger protein 276
ZNF32 zinc finger protein 32
ZNF528 zinc finger protein 528
ZNF862 zinc finger protein 862