rilmenidine-5107 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

195 genes differentially expressed following the rilmenidine-5107 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ABCB6 ATP-binding cassette, sub-family B (MDR/TAP), member 6 (Langereis blood group)
ABCG1 ATP-binding cassette, sub-family G (WHITE), member 1
ADCY9 adenylate cyclase 9
ADGRA3 adhesion G protein-coupled receptor A3
ARHGAP22 Rho GTPase activating protein 22
ARID5A AT rich interactive domain 5A (MRF1-like)
ARMCX4 armadillo repeat containing, X-linked 4
ATF7IP activating transcription factor 7 interacting protein
BMP1 bone morphogenetic protein 1
C11ORF63 chromosome 11 open reading frame 63
CACNG4 calcium channel, voltage-dependent, gamma subunit 4
CAMKMT calmodulin-lysine N-methyltransferase
CCDC28B coiled-coil domain containing 28B
CENPT centromere protein T
CHMP6 charged multivesicular body protein 6
CLDN15 claudin 15
CNOT4 CCR4-NOT transcription complex, subunit 4
COQ7 coenzyme Q7 homolog, ubiquinone (yeast)
CYP1A1 cytochrome P450, family 1, subfamily A, polypeptide 1
DBNDD1 dysbindin (dystrobrevin binding protein 1) domain containing 1
DHODH dihydroorotate dehydrogenase (quinone)
DNAJB12 DnaJ (Hsp40) homolog, subfamily B, member 12
DUS2 dihydrouridine synthase 2
EFNB1 ephrin-B1
EGLN2 egl-9 family hypoxia-inducible factor 2
ELK4 ELK4, ETS-domain protein (SRF accessory protein 1)
EPB41L1 erythrocyte membrane protein band 4.1-like 1
EPS8L1 EPS8-like 1
FABP4 fatty acid binding protein 4, adipocyte
FAM53B family with sequence similarity 53, member B
FAM63B family with sequence similarity 63, member B
GUSBP3 glucuronidase, beta pseudogene 3
HERC6 HECT and RLD domain containing E3 ubiquitin protein ligase family member 6
HRH2 histamine receptor H2
HSPA12A heat shock 70kDa protein 12A
HSPA6 heat shock 70kDa protein 6 (HSP70B')
HSPG2 heparan sulfate proteoglycan 2
IDUA iduronidase, alpha-L-
IL17RB interleukin 17 receptor B
INADL InaD-like (Drosophila)
JRK Jrk homolog (mouse)
KCNAB2 potassium channel, voltage gated subfamily A regulatory beta subunit 2
KCTD13 potassium channel tetramerization domain containing 13
KHSRP KH-type splicing regulatory protein
LIG3 ligase III, DNA, ATP-dependent
LIPG lipase, endothelial
LRP2 low density lipoprotein receptor-related protein 2
LRRC1 leucine rich repeat containing 1
MFAP3L microfibrillar-associated protein 3-like
MPPE1 metallophosphoesterase 1
NDNF neuron-derived neurotrophic factor
ONECUT2 one cut homeobox 2
OR2B6 olfactory receptor, family 2, subfamily B, member 6
PELI2 pellino E3 ubiquitin protein ligase family member 2
PPP3R1 protein phosphatase 3, regulatory subunit B, alpha
PTK2B protein tyrosine kinase 2 beta
PTPRF protein tyrosine phosphatase, receptor type, F
PVR poliovirus receptor
QPCTL glutaminyl-peptide cyclotransferase-like
RABGAP1 RAB GTPase activating protein 1
RB1 retinoblastoma 1
RBFOX1 RNA binding protein, fox-1 homolog (C. elegans) 1
RCN3 reticulocalbin 3, EF-hand calcium binding domain
RGS10 regulator of G-protein signaling 10
RNGTT RNA guanylyltransferase and 5'-phosphatase
RPL35A ribosomal protein L35a
RPS6KA2 ribosomal protein S6 kinase, 90kDa, polypeptide 2
RPS9 ribosomal protein S9
RUSC2 RUN and SH3 domain containing 2
SARM1 sterile alpha and TIR motif containing 1
SETDB1 SET domain, bifurcated 1
SFXN3 sideroflexin 3
SIRPA signal-regulatory protein alpha
SLC25A44 solute carrier family 25, member 44
SLC4A3 solute carrier family 4 (anion exchanger), member 3
SLC9A8 solute carrier family 9, subfamily A (NHE8, cation proton antiporter 8), member 8
SORBS1 sorbin and SH3 domain containing 1
SPTB spectrin, beta, erythrocytic
ST8SIA3 ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 3
STOM stomatin
STXBP6 syntaxin binding protein 6 (amisyn)
SYNPO2L synaptopodin 2-like
TBC1D30 TBC1 domain family, member 30
TBC1D8B TBC1 domain family, member 8B (with GRAM domain)
TBC1D9B TBC1 domain family, member 9B (with GRAM domain)
TLN2 talin 2
TOB2 transducer of ERBB2, 2
TSKU tsukushi, small leucine rich proteoglycan
TTC30A tetratricopeptide repeat domain 30A
TTLL5 tubulin tyrosine ligase-like family member 5
TXNRD3 thioredoxin reductase 3
UNC119 unc-119 homolog (C. elegans)
URB1 URB1 ribosome biogenesis 1 homolog (S. cerevisiae)
VPRBP Vpr (HIV-1) binding protein
XPNPEP1 X-prolyl aminopeptidase (aminopeptidase P) 1, soluble
ZCCHC11 zinc finger, CCHC domain containing 11
ZFHX3 zinc finger homeobox 3
ZFP36L1 ZFP36 ring finger protein-like 1

decreased expression

Symbol Name
APOLD1 apolipoprotein L domain containing 1
ARSB arylsulfatase B
ASCC1 activating signal cointegrator 1 complex subunit 1
ASPSCR1 alveolar soft part sarcoma chromosome region, candidate 1
ATAT1 alpha tubulin acetyltransferase 1
B3GALT4 UDP-Gal:betaGlcNAc beta 1,3-galactosyltransferase, polypeptide 4
B9D2 B9 protein domain 2
BEND5 BEN domain containing 5
BTC betacellulin
C14ORF105 chromosome 14 open reading frame 105
C1ORF21 chromosome 1 open reading frame 21
C4ORF19 chromosome 4 open reading frame 19
CABYR calcium binding tyrosine-(Y)-phosphorylation regulated
CDIP1 cell death-inducing p53 target 1
CDK6 cyclin-dependent kinase 6
CDKL3 cyclin-dependent kinase-like 3
CDON cell adhesion associated, oncogene regulated
CHM choroideremia (Rab escort protein 1)
CLDN11 claudin 11
COX6A2 cytochrome c oxidase subunit VIa polypeptide 2
CST6 cystatin E/M
CTAGE9 CTAGE family, member 9
CYBRD1 cytochrome b reductase 1
DEPTOR DEP domain containing MTOR-interacting protein
DSPP dentin sialophosphoprotein
EDIL3 EGF-like repeats and discoidin I-like domains 3
EYA3 EYA transcriptional coactivator and phosphatase 3
FAM186A family with sequence similarity 186, member A
FBXO2 F-box protein 2
GDAP1 ganglioside induced differentiation associated protein 1
GEMIN8 gem (nuclear organelle) associated protein 8
GLTSCR1 glioma tumor suppressor candidate region gene 1
GNA13 guanine nucleotide binding protein (G protein), alpha 13
GNA14 guanine nucleotide binding protein (G protein), alpha 14
GPRIN2 G protein regulated inducer of neurite outgrowth 2
GPX2 glutathione peroxidase 2
GTF2I general transcription factor IIi
GUCY1B2 guanylate cyclase 1, soluble, beta 2 (pseudogene)
HIST1H2AJ histone cluster 1, H2aj
HYMAI hydatidiform mole associated and imprinted (non-protein coding)
IFI6 interferon, alpha-inducible protein 6
IFIT2 interferon-induced protein with tetratricopeptide repeats 2
IFNA2 interferon, alpha 2
IFNAR1 interferon (alpha, beta and omega) receptor 1
INCENP inner centromere protein antigens 135/155kDa
IQSEC2 IQ motif and Sec7 domain 2
IRAK4 interleukin-1 receptor-associated kinase 4
KCNN1 potassium channel, calcium activated intermediate/small conductance subfamily N alpha, member 1
KIAA1549L KIAA1549-like
KPNA5 karyopherin alpha 5 (importin alpha 6)
LINC00339 long intergenic non-protein coding RNA 339
LRP3 low density lipoprotein receptor-related protein 3
MT1M metallothionein 1M
MUC3A mucin 3A, cell surface associated
MUC3B mucin 3B, cell surface associated
MXRA8 matrix-remodelling associated 8
MYL9 myosin, light chain 9, regulatory
NINJ1 ninjurin 1
NPM3 nucleophosmin/nucleoplasmin 3
NT5M 5',3'-nucleotidase, mitochondrial
NTF3 neurotrophin 3
OSMR oncostatin M receptor
PACS1 phosphofurin acidic cluster sorting protein 1
PAK3 p21 protein (Cdc42/Rac)-activated kinase 3
PER3 period circadian clock 3
PRSS22 protease, serine, 22
QSER1 glutamine and serine rich 1
RAB17 RAB17, member RAS oncogene family
RAB3IL1 RAB3A interacting protein (rabin3)-like 1
RAC3 ras-related C3 botulinum toxin substrate 3 (rho family, small GTP binding protein Rac3)
RARRES3 retinoic acid receptor responder (tazarotene induced) 3
RSPH14 radial spoke head 14 homolog (Chlamydomonas)
SAYSD1 SAYSVFN motif domain containing 1
SCEL sciellin
SENP7 SUMO1/sentrin specific peptidase 7
SLC17A2 solute carrier family 17, member 2
SLC35F6 solute carrier family 35, member F6
SLC3A1 solute carrier family 3 (amino acid transporter heavy chain), member 1
SLC44A1 solute carrier family 44 (choline transporter), member 1
SLN sarcolipin
STAG3 stromal antigen 3
SULT2B1 sulfotransferase family, cytosolic, 2B, member 1
TAF15 TAF15 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 68kDa
TBXAS1 thromboxane A synthase 1 (platelet)
TFAP4 transcription factor AP-4 (activating enhancer binding protein 4)
TIGD6 tigger transposable element derived 6
TMEM212 transmembrane protein 212
TRIM25 tripartite motif containing 25
TTLL1 tubulin tyrosine ligase-like family member 1
USP18 ubiquitin specific peptidase 18
USP20 ubiquitin specific peptidase 20
USP27X ubiquitin specific peptidase 27, X-linked
UTRN utrophin
ZNF141 zinc finger protein 141
ZNF205 zinc finger protein 205
ZNF442 zinc finger protein 442
ZNF671 zinc finger protein 671