| Dataset | CMAP Signatures of Differentially Expressed Genes for Small Molecules |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis) |
| Similar Terms | |
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199 genes differentially expressed following the rilmenidine-5532 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
| Symbol | Name |
|---|---|
| A1CF | APOBEC1 complementation factor |
| AGT | angiotensinogen (serpin peptidase inhibitor, clade A, member 8) |
| AHI1 | Abelson helper integration site 1 |
| AKAP7 | A kinase (PRKA) anchor protein 7 |
| AKR1B1 | aldo-keto reductase family 1, member B1 (aldose reductase) |
| ALOXE3 | arachidonate lipoxygenase 3 |
| APOE | apolipoprotein E |
| ARHGEF10 | Rho guanine nucleotide exchange factor (GEF) 10 |
| BTRC | beta-transducin repeat containing E3 ubiquitin protein ligase |
| C14ORF1 | chromosome 14 open reading frame 1 |
| CEP164 | centrosomal protein 164kDa |
| CHRNA10 | cholinergic receptor, nicotinic, alpha 10 (neuronal) |
| CHRNB3 | cholinergic receptor, nicotinic, beta 3 (neuronal) |
| CLGN | calmegin |
| CNTD2 | cyclin N-terminal domain containing 2 |
| COL21A1 | collagen, type XXI, alpha 1 |
| COX6A2 | cytochrome c oxidase subunit VIa polypeptide 2 |
| CRTC1 | CREB regulated transcription coactivator 1 |
| CSF1 | colony stimulating factor 1 (macrophage) |
| DFNA5 | deafness, autosomal dominant 5 |
| DNAH17 | dynein, axonemal, heavy chain 17 |
| DUSP6 | dual specificity phosphatase 6 |
| EDRF1 | erythroid differentiation regulatory factor 1 |
| ELP6 | elongator acetyltransferase complex subunit 6 |
| EML2 | echinoderm microtubule associated protein like 2 |
| ENTPD7 | ectonucleoside triphosphate diphosphohydrolase 7 |
| ERAP1 | endoplasmic reticulum aminopeptidase 1 |
| FBXO21 | F-box protein 21 |
| FGFR1 | fibroblast growth factor receptor 1 |
| FLT4 | fms-related tyrosine kinase 4 |
| FOXE1 | forkhead box E1 |
| FRZB | frizzled-related protein |
| FZR1 | fizzy/cell division cycle 20 related 1 (Drosophila) |
| GABRA1 | gamma-aminobutyric acid (GABA) A receptor, alpha 1 |
| GAL | galanin/GMAP prepropeptide |
| GALNT12 | polypeptide N-acetylgalactosaminyltransferase 12 |
| GLRX | glutaredoxin (thioltransferase) |
| HDAC6 | histone deacetylase 6 |
| HMOX1 | heme oxygenase 1 |
| HOXA4 | homeobox A4 |
| IFI6 | interferon, alpha-inducible protein 6 |
| ITGB3 | integrin, beta 3 (platelet glycoprotein IIIa, antigen CD61) |
| KHK | ketohexokinase (fructokinase) |
| LAT2 | linker for activation of T cells family, member 2 |
| LRP12 | low density lipoprotein receptor-related protein 12 |
| LRRFIP1 | leucine rich repeat (in FLII) interacting protein 1 |
| MAPKAPK2 | mitogen-activated protein kinase-activated protein kinase 2 |
| MAS1 | MAS1 proto-oncogene, G protein-coupled receptor |
| MAX | MYC associated factor X |
| MBNL2 | muscleblind-like splicing regulator 2 |
| MDM4 | MDM4, p53 regulator |
| MPO | myeloperoxidase |
| MTA1 | metastasis associated 1 |
| NAG18 | NAG18 mRNA |
| NF1 | neurofibromin 1 |
| NUDCD3 | NudC domain containing 3 |
| NXPE3 | neurexophilin and PC-esterase domain family, member 3 |
| PAX5 | paired box 5 |
| PDE6B | phosphodiesterase 6B, cGMP-specific, rod, beta |
| PTGER3 | prostaglandin E receptor 3 (subtype EP3) |
| RANBP10 | RAN binding protein 10 |
| RAPGEF2 | Rap guanine nucleotide exchange factor (GEF) 2 |
| RGS7 | regulator of G-protein signaling 7 |
| RORA | RAR-related orphan receptor A |
| RRBP1 | ribosome binding protein 1 |
| S100A8 | S100 calcium binding protein A8 |
| S100A9 | S100 calcium binding protein A9 |
| SCAI | suppressor of cancer cell invasion |
| SCN2B | sodium channel, voltage gated, type II beta subunit |
| SCUBE3 | signal peptide, CUB domain, EGF-like 3 |
| SEMA7A | semaphorin 7A, GPI membrane anchor (John Milton Hagen blood group) |
| SERPINI1 | serpin peptidase inhibitor, clade I (neuroserpin), member 1 |
| SIT1 | signaling threshold regulating transmembrane adaptor 1 |
| SLC12A6 | solute carrier family 12 (potassium/chloride transporter), member 6 |
| SLC1A4 | solute carrier family 1 (glutamate/neutral amino acid transporter), member 4 |
| SLC25A44 | solute carrier family 25, member 44 |
| SLC2A5 | solute carrier family 2 (facilitated glucose/fructose transporter), member 5 |
| SLC47A1 | solute carrier family 47 (multidrug and toxin extrusion), member 1 |
| SORBS2 | sorbin and SH3 domain containing 2 |
| SPINK5 | serine peptidase inhibitor, Kazal type 5 |
| SPTBN5 | spectrin, beta, non-erythrocytic 5 |
| STAT2 | signal transducer and activator of transcription 2, 113kDa |
| STRN3 | striatin, calmodulin binding protein 3 |
| SYCP1 | synaptonemal complex protein 1 |
| TMEM63A | transmembrane protein 63A |
| TNFSF10 | tumor necrosis factor (ligand) superfamily, member 10 |
| TNRC6B | trinucleotide repeat containing 6B |
| TPSG1 | tryptase gamma 1 |
| TRA2A | transformer 2 alpha homolog (Drosophila) |
| TRIM3 | tripartite motif containing 3 |
| TRIP11 | thyroid hormone receptor interactor 11 |
| USP20 | ubiquitin specific peptidase 20 |
| UTP14A | UTP14, U3 small nucleolar ribonucleoprotein, homolog A (yeast) |
| VAC14 | Vac14 homolog (S. cerevisiae) |
| ZBTB22 | zinc finger and BTB domain containing 22 |
| ZC3H7B | zinc finger CCCH-type containing 7B |
| ZNF204P | zinc finger protein 204, pseudogene |
| ZNF440 | zinc finger protein 440 |
| ZNF778 | zinc finger protein 778 |
| Symbol | Name |
|---|---|
| ACOT8 | acyl-CoA thioesterase 8 |
| ALPK1 | alpha-kinase 1 |
| ANKRD36 | ankyrin repeat domain 36 |
| ATP13A2 | ATPase type 13A2 |
| AXIN1 | axin 1 |
| BCAS1 | breast carcinoma amplified sequence 1 |
| C17ORF70 | chromosome 17 open reading frame 70 |
| CALCOCO1 | calcium binding and coiled-coil domain 1 |
| CAPN15 | calpain 15 |
| CCDC130 | coiled-coil domain containing 130 |
| CCDC28A | coiled-coil domain containing 28A |
| CCDC69 | coiled-coil domain containing 69 |
| CCDC94 | coiled-coil domain containing 94 |
| CCNO | cyclin O |
| CDK20 | cyclin-dependent kinase 20 |
| CENPO | centromere protein O |
| CES3 | carboxylesterase 3 |
| CHKB | choline kinase beta |
| CINP | cyclin-dependent kinase 2 interacting protein |
| CLEC4E | C-type lectin domain family 4, member E |
| CLSPN | claspin |
| CMAS | cytidine monophosphate N-acetylneuraminic acid synthetase |
| CRYBG3 | beta-gamma crystallin domain containing 3 |
| DHRS11 | dehydrogenase/reductase (SDR family) member 11 |
| DNA2 | DNA replication helicase/nuclease 2 |
| DNAJB2 | DnaJ (Hsp40) homolog, subfamily B, member 2 |
| DUSP2 | dual specificity phosphatase 2 |
| EAF2 | ELL associated factor 2 |
| EFNA3 | ephrin-A3 |
| ELSPBP1 | epididymal sperm binding protein 1 |
| ERMAP | erythroblast membrane-associated protein (Scianna blood group) |
| ETNK2 | ethanolamine kinase 2 |
| F2R | coagulation factor II (thrombin) receptor |
| FAM110B | family with sequence similarity 110, member B |
| FAM86C1 | family with sequence similarity 86, member C1 |
| FGD6 | FYVE, RhoGEF and PH domain containing 6 |
| FUT1 | fucosyltransferase 1 (galactoside 2-alpha-L-fucosyltransferase, H blood group) |
| GABPA | GA binding protein transcription factor, alpha subunit 60kDa |
| GAREM | GRB2 associated, regulator of MAPK1 |
| GID4 | GID complex subunit 4 |
| GNB1L | guanine nucleotide binding protein (G protein), beta polypeptide 1-like |
| HIST1H1D | histone cluster 1, H1d |
| HIST1H2BI | histone cluster 1, H2bi |
| HMHA1 | histocompatibility (minor) HA-1 |
| HPS6 | Hermansky-Pudlak syndrome 6 |
| HS1BP3 | HCLS1 binding protein 3 |
| HSD17B11 | hydroxysteroid (17-beta) dehydrogenase 11 |
| HSPA2 | heat shock 70kDa protein 2 |
| HTRA1 | HtrA serine peptidase 1 |
| IFNAR1 | interferon (alpha, beta and omega) receptor 1 |
| IMPACT | impact RWD domain protein |
| KCNF1 | potassium channel, voltage gated modifier subfamily F, member 1 |
| KCNJ3 | potassium channel, inwardly rectifying subfamily J, member 3 |
| KCTD7 | potassium channel tetramerization domain containing 7 |
| KIAA0753 | KIAA0753 |
| LAMA3 | laminin, alpha 3 |
| LAX1 | lymphocyte transmembrane adaptor 1 |
| LHX6 | LIM homeobox 6 |
| LOC202181 | SUMO-interacting motifs containing 1 pseudogene |
| LRRC8E | leucine rich repeat containing 8 family, member E |
| MANBA | mannosidase, beta A, lysosomal |
| MBTPS2 | membrane-bound transcription factor peptidase, site 2 |
| MRPL41 | mitochondrial ribosomal protein L41 |
| NES | nestin |
| NHEJ1 | nonhomologous end-joining factor 1 |
| PADI1 | peptidyl arginine deiminase, type I |
| PARD6A | par-6 family cell polarity regulator alpha |
| PARG | poly (ADP-ribose) glycohydrolase |
| PGPEP1 | pyroglutamyl-peptidase I |
| PLCB3 | phospholipase C, beta 3 (phosphatidylinositol-specific) |
| PLCXD1 | phosphatidylinositol-specific phospholipase C, X domain containing 1 |
| PLEKHM2 | pleckstrin homology domain containing, family M (with RUN domain) member 2 |
| PPIP5K1 | diphosphoinositol pentakisphosphate kinase 1 |
| R3HCC1L | R3H domain and coiled-coil containing 1-like |
| RFTN1 | raftlin, lipid raft linker 1 |
| RGS19 | regulator of G-protein signaling 19 |
| RHPN1-AS1 | RHPN1 antisense RNA 1 (head to head) |
| RNF31 | ring finger protein 31 |
| RNF43 | ring finger protein 43 |
| RPH3AL | rabphilin 3A-like (without C2 domains) |
| SLMO1 | slowmo homolog 1 (Drosophila) |
| SMG9 | SMG9 nonsense mediated mRNA decay factor |
| STAG3 | stromal antigen 3 |
| STAG3L4 | stromal antigen 3-like 4 (pseudogene) |
| TINF2 | TERF1 (TRF1)-interacting nuclear factor 2 |
| TMPRSS3 | transmembrane protease, serine 3 |
| TNFSF9 | tumor necrosis factor (ligand) superfamily, member 9 |
| TOPORS | topoisomerase I binding, arginine/serine-rich, E3 ubiquitin protein ligase |
| TRAF6 | TNF receptor-associated factor 6, E3 ubiquitin protein ligase |
| TRAPPC6A | trafficking protein particle complex 6A |
| TTC33 | tetratricopeptide repeat domain 33 |
| TWF2 | twinfilin actin binding protein 2 |
| VWA1 | von Willebrand factor A domain containing 1 |
| WDR76 | WD repeat domain 76 |
| XAB2 | XPA binding protein 2 |
| ZAK | sterile alpha motif and leucine zipper containing kinase AZK |
| ZNF141 | zinc finger protein 141 |
| ZNF276 | zinc finger protein 276 |
| ZNF446 | zinc finger protein 446 |
| ZSWIM1 | zinc finger, SWIM-type containing 1 |
