| Dataset | CMAP Signatures of Differentially Expressed Genes for Small Molecules |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis) |
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196 genes differentially expressed following the riluzole-4689 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
| Symbol | Name |
|---|---|
| ABCB6 | ATP-binding cassette, sub-family B (MDR/TAP), member 6 (Langereis blood group) |
| ABCB9 | ATP-binding cassette, sub-family B (MDR/TAP), member 9 |
| ADGRG2 | adhesion G protein-coupled receptor G2 |
| ADM | adrenomedullin |
| AKAP8L | A kinase (PRKA) anchor protein 8-like |
| ALDH3A1 | aldehyde dehydrogenase 3 family, member A1 |
| ALPPL2 | alkaline phosphatase, placental-like 2 |
| AMACR | alpha-methylacyl-CoA racemase |
| ANGEL2 | angel homolog 2 (Drosophila) |
| ANP32A-IT1 | ANP32A intronic transcript 1 |
| APOLD1 | apolipoprotein L domain containing 1 |
| AQP3 | aquaporin 3 (Gill blood group) |
| BMP1 | bone morphogenetic protein 1 |
| BRINP2 | bone morphogenetic protein/retinoic acid inducible neural-specific 2 |
| C2ORF72 | chromosome 2 open reading frame 72 |
| CAMK4 | calcium/calmodulin-dependent protein kinase IV |
| CFAP45 | cilia and flagella associated protein 45 |
| CFHR4 | complement factor H-related 4 |
| CTBP2 | C-terminal binding protein 2 |
| DFFB | DNA fragmentation factor, 40kDa, beta polypeptide (caspase-activated DNase) |
| DMTN | dematin actin binding protein |
| DNM3 | dynamin 3 |
| EPHB2 | EPH receptor B2 |
| ERO1LB | ERO1-like beta (S. cerevisiae) |
| FAM149A | family with sequence similarity 149, member A |
| FCN1 | ficolin (collagen/fibrinogen domain containing) 1 |
| FRMD4A | FERM domain containing 4A |
| GABRA2 | gamma-aminobutyric acid (GABA) A receptor, alpha 2 |
| GIT2 | G protein-coupled receptor kinase interacting ArfGAP 2 |
| GRB10 | growth factor receptor-bound protein 10 |
| GRIP2 | glutamate receptor interacting protein 2 |
| GRK5 | G protein-coupled receptor kinase 5 |
| HIST1H3E | histone cluster 1, H3e |
| HSPA6 | heat shock 70kDa protein 6 (HSP70B') |
| ICOSLG | inducible T-cell co-stimulator ligand |
| IL5RA | interleukin 5 receptor, alpha |
| KLF2 | Kruppel-like factor 2 |
| LAIR1 | leukocyte-associated immunoglobulin-like receptor 1 |
| LAMC2 | laminin, gamma 2 |
| LAMP1 | lysosomal-associated membrane protein 1 |
| LARP7 | La ribonucleoprotein domain family, member 7 |
| LLPH | LLP homolog, long-term synaptic facilitation (Aplysia) |
| LOC644450 | uncharacterized LOC644450 |
| LRRN3 | leucine rich repeat neuronal 3 |
| MAK | male germ cell-associated kinase |
| MCAM | melanoma cell adhesion molecule |
| MEGF8 | multiple EGF-like-domains 8 |
| MUC6 | mucin 6, oligomeric mucus/gel-forming |
| NFATC3 | nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 3 |
| NFKBIL1 | nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor-like 1 |
| NPR2 | natriuretic peptide receptor 2 |
| NPY4R | neuropeptide Y receptor Y4 |
| NR3C1 | nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor) |
| PALM | paralemmin |
| PAOX | polyamine oxidase (exo-N4-amino) |
| PARD6B | par-6 family cell polarity regulator beta |
| PCDHB13 | protocadherin beta 13 |
| PCSK7 | proprotein convertase subtilisin/kexin type 7 |
| PHF20 | PHD finger protein 20 |
| PLA2G4C | phospholipase A2, group IVC (cytosolic, calcium-independent) |
| PLD2 | phospholipase D2 |
| PLEKHS1 | pleckstrin homology domain containing, family S member 1 |
| PMS2P3 | postmeiotic segregation increased 2 pseudogene 3 |
| PPIP5K1 | diphosphoinositol pentakisphosphate kinase 1 |
| PRDM2 | PR domain containing 2, with ZNF domain |
| PVR | poliovirus receptor |
| RAB3B | RAB3B, member RAS oncogene family |
| RALGPS2 | Ral GEF with PH domain and SH3 binding motif 2 |
| RHAG | Rh-associated glycoprotein |
| RMND5A | required for meiotic nuclear division 5 homolog A (S. cerevisiae) |
| RND1 | Rho family GTPase 1 |
| RNF122 | ring finger protein 122 |
| SAP30 | Sin3A-associated protein, 30kDa |
| SCAND2P | SCAN domain containing 2 pseudogene |
| SCD5 | stearoyl-CoA desaturase 5 |
| SCN10A | sodium channel, voltage gated, type X alpha subunit |
| SCRN3 | secernin 3 |
| SERHL2 | serine hydrolase-like 2 |
| SERPINI1 | serpin peptidase inhibitor, clade I (neuroserpin), member 1 |
| SIDT2 | SID1 transmembrane family, member 2 |
| SMARCD3 | SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily d, member 3 |
| SPRY4 | sprouty homolog 4 (Drosophila) |
| SRSF6 | serine/arginine-rich splicing factor 6 |
| ST5 | suppression of tumorigenicity 5 |
| TAOK1 | TAO kinase 1 |
| TEP1 | telomerase-associated protein 1 |
| TESC | tescalcin |
| TFEB | transcription factor EB |
| TOP3B | topoisomerase (DNA) III beta |
| TRIM15 | tripartite motif containing 15 |
| TROVE2 | TROVE domain family, member 2 |
| TUBA3C | tubulin, alpha 3c |
| TYRP1 | tyrosinase-related protein 1 |
| UHRF1BP1L | UHRF1 binding protein 1-like |
| WIPI2 | WD repeat domain, phosphoinositide interacting 2 |
| XRCC6 | X-ray repair complementing defective repair in Chinese hamster cells 6 |
| YTHDC2 | YTH domain containing 2 |
| ZFP37 | ZFP37 zinc finger protein |
| ZNF287 | zinc finger protein 287 |
| Symbol | Name |
|---|---|
| A4GALT | alpha 1,4-galactosyltransferase |
| ACSL4 | acyl-CoA synthetase long-chain family member 4 |
| ANKEF1 | ankyrin repeat and EF-hand domain containing 1 |
| ARHGEF17 | Rho guanine nucleotide exchange factor (GEF) 17 |
| ASAP1-IT1 | ASAP1 intronic transcript 1 |
| ATAD5 | ATPase family, AAA domain containing 5 |
| BGLAP | bone gamma-carboxyglutamate (gla) protein |
| C7ORF69 | chromosome 7 open reading frame 69 |
| CACNA1H | calcium channel, voltage-dependent, T type, alpha 1H subunit |
| CCDC69 | coiled-coil domain containing 69 |
| CD2AP | CD2-associated protein |
| CD3D | CD3d molecule, delta (CD3-TCR complex) |
| CD79A | CD79a molecule, immunoglobulin-associated alpha |
| CLIC2 | chloride intracellular channel 2 |
| CORT | cortistatin |
| CRABP1 | cellular retinoic acid binding protein 1 |
| CRIP1 | cysteine-rich protein 1 (intestinal) |
| CRYGC | crystallin, gamma C |
| CYP4F11 | cytochrome P450, family 4, subfamily F, polypeptide 11 |
| DEF6 | differentially expressed in FDCP 6 homolog (mouse) |
| DNALI1 | dynein, axonemal, light intermediate chain 1 |
| DOC2A | double C2-like domains, alpha |
| DRD1 | dopamine receptor D1 |
| DTX4 | deltex 4, E3 ubiquitin ligase |
| ENTPD5 | ectonucleoside triphosphate diphosphohydrolase 5 |
| FBRS | fibrosin |
| FLJ21369 | uncharacterized protein FLJ21369 |
| FOXRED2 | FAD-dependent oxidoreductase domain containing 2 |
| GLRA1 | glycine receptor, alpha 1 |
| GNG4 | guanine nucleotide binding protein (G protein), gamma 4 |
| GTF2A1 | general transcription factor IIA, 1, 19/37kDa |
| HIST1H1D | histone cluster 1, H1d |
| HIST1H2AJ | histone cluster 1, H2aj |
| HIST1H2AL | histone cluster 1, H2al |
| HLA-J | major histocompatibility complex, class I, J (pseudogene) |
| INF2 | inverted formin, FH2 and WH2 domain containing |
| JADE3 | jade family PHD finger 3 |
| KBTBD11 | kelch repeat and BTB (POZ) domain containing 11 |
| KCNMB3 | potassium channel subfamily M regulatory beta subunit 3 |
| KIAA0894 | KIAA0894 protein |
| LHX6 | LIM homeobox 6 |
| LIME1 | Lck interacting transmembrane adaptor 1 |
| LIN7A | lin-7 homolog A (C. elegans) |
| LOC202181 | SUMO-interacting motifs containing 1 pseudogene |
| LOC257152 | uncharacterized LOC257152 |
| LRRC20 | leucine rich repeat containing 20 |
| LRRC37A2 | leucine rich repeat containing 37, member A2 |
| MAPK12 | mitogen-activated protein kinase 12 |
| MAST3 | microtubule associated serine/threonine kinase 3 |
| MBL1P | mannose-binding lectin (protein A) 1, pseudogene |
| MRPL41 | mitochondrial ribosomal protein L41 |
| MTA2 | metastasis associated 1 family, member 2 |
| MUC3B | mucin 3B, cell surface associated |
| MVP | major vault protein |
| MYLK | myosin light chain kinase |
| NECAB3 | N-terminal EF-hand calcium binding protein 3 |
| NEUROD1 | neuronal differentiation 1 |
| NPFFR1 | neuropeptide FF receptor 1 |
| NPM3 | nucleophosmin/nucleoplasmin 3 |
| OR7E156P | olfactory receptor, family 7, subfamily E, member 156 pseudogene |
| PDP1 | pyruvate dehyrogenase phosphatase catalytic subunit 1 |
| PLA2G15 | phospholipase A2, group XV |
| PPP1R3C | protein phosphatase 1, regulatory subunit 3C |
| PRB3 | proline-rich protein BstNI subfamily 3 |
| PRKACG | protein kinase, cAMP-dependent, catalytic, gamma |
| PRSS53 | protease, serine, 53 |
| PTPRCAP | protein tyrosine phosphatase, receptor type, C-associated protein |
| RAB33B | RAB33B, member RAS oncogene family |
| RAB3A | RAB3A, member RAS oncogene family |
| RCN1 | reticulocalbin 1, EF-hand calcium binding domain |
| RELB | v-rel avian reticuloendotheliosis viral oncogene homolog B |
| RNF126P1 | ring finger protein 126 pseudogene 1 |
| SAMD9 | sterile alpha motif domain containing 9 |
| SEMA4D | sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4D |
| SLC25A23 | solute carrier family 25 (mitochondrial carrier; phosphate carrier), member 23 |
| SNTA1 | syntrophin, alpha 1 |
| SPRR2B | small proline-rich protein 2B |
| SPRY2 | sprouty homolog 2 (Drosophila) |
| SPTLC3 | serine palmitoyltransferase, long chain base subunit 3 |
| STAG3 | stromal antigen 3 |
| TAB1 | TGF-beta activated kinase 1/MAP3K7 binding protein 1 |
| TMC5 | transmembrane channel-like 5 |
| TMEM158 | transmembrane protein 158 (gene/pseudogene) |
| TMEM212 | transmembrane protein 212 |
| TUBA3D | tubulin, alpha 3d |
| TUBB2B | tubulin, beta 2B class IIb |
| TUT1 | terminal uridylyl transferase 1, U6 snRNA-specific |
| USB1 | U6 snRNA biogenesis 1 |
| USP27X | ubiquitin specific peptidase 27, X-linked |
| VASH1 | vasohibin 1 |
| VASH2 | vasohibin 2 |
| VAX2 | ventral anterior homeobox 2 |
| VIM | vimentin |
| ZNF350 | zinc finger protein 350 |
| ZNF37BP | zinc finger protein 37B, pseudogene |
| ZNF446 | zinc finger protein 446 |
| ZNF665 | zinc finger protein 665 |