rimexolone-2955 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

195 genes differentially expressed following the rimexolone-2955 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ABCA3 ATP-binding cassette, sub-family A (ABC1), member 3
ADGRG2 adhesion G protein-coupled receptor G2
ADORA3 adenosine A3 receptor
AGAP2 ArfGAP with GTPase domain, ankyrin repeat and PH domain 2
AGPAT3 1-acylglycerol-3-phosphate O-acyltransferase 3
ALDH1L1 aldehyde dehydrogenase 1 family, member L1
APOE apolipoprotein E
AREG amphiregulin
ATP11A ATPase, class VI, type 11A
BIN1 bridging integrator 1
C20ORF27 chromosome 20 open reading frame 27
CACNB1 calcium channel, voltage-dependent, beta 1 subunit
CAMSAP1 calmodulin regulated spectrin-associated protein 1
CCDC106 coiled-coil domain containing 106
CCL20 chemokine (C-C motif) ligand 20
CD80 CD80 molecule
CDS1 CDP-diacylglycerol synthase (phosphatidate cytidylyltransferase) 1
CHRNA10 cholinergic receptor, nicotinic, alpha 10 (neuronal)
COL4A2 collagen, type IV, alpha 2
COL6A1 collagen, type VI, alpha 1
COLQ collagen-like tail subunit (single strand of homotrimer) of asymmetric acetylcholinesterase
DCAF15 DDB1 and CUL4 associated factor 15
DLG3 discs, large homolog 3 (Drosophila)
DUSP1 dual specificity phosphatase 1
DZIP3 DAZ interacting zinc finger protein 3
EDDM3A epididymal protein 3A
EFNA3 ephrin-A3
EFNA5 ephrin-A5
ESR1 estrogen receptor 1
EXD3 exonuclease 3'-5' domain containing 3
FASTK Fas-activated serine/threonine kinase
FCMR Fc fragment of IgM receptor
FGR FGR proto-oncogene, Src family tyrosine kinase
FKBP5 FK506 binding protein 5
FLRT2 fibronectin leucine rich transmembrane protein 2
FMO5 flavin containing monooxygenase 5
FPR1 formyl peptide receptor 1
GNB1L guanine nucleotide binding protein (G protein), beta polypeptide 1-like
GPR21 G protein-coupled receptor 21
HIST1H3G histone cluster 1, H3g
HLA-DPA1 major histocompatibility complex, class II, DP alpha 1
HNF1A HNF1 homeobox A
HOMER3 homer scaffolding protein 3
ICOSLG inducible T-cell co-stimulator ligand
IDUA iduronidase, alpha-L-
IL1R2 interleukin 1 receptor, type II
IL24 interleukin 24
IL6ST interleukin 6 signal transducer
INHBA inhibin, beta A
INPP4A inositol polyphosphate-4-phosphatase, type I, 107kDa
IQCA1 IQ motif containing with AAA domain 1
JAG1 jagged 1
KYNU kynureninase
LOC729164 hCG1732469
LRRC40 leucine rich repeat containing 40
MAP3K1 mitogen-activated protein kinase kinase kinase 1, E3 ubiquitin protein ligase
MLLT10 myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 10
MTA1 metastasis associated 1
PDLIM2 PDZ and LIM domain 2 (mystique)
PER1 period circadian clock 1
PICK1 protein interacting with PRKCA 1
PIN1P1 peptidylprolyl cis/trans isomerase, NIMA-interacting 1 pseudogene 1
PLCL1 phospholipase C-like 1
PPT2 palmitoyl-protein thioesterase 2
PRR7 proline rich 7 (synaptic)
PYGB phosphorylase, glycogen; brain
RNF39 ring finger protein 39
SAG S-antigen; retina and pineal gland (arrestin)
SDC2 syndecan 2
SH3TC1 SH3 domain and tetratricopeptide repeats 1
SIRPA signal-regulatory protein alpha
SLC11A1 solute carrier family 11 (proton-coupled divalent metal ion transporter), member 1
SLC13A3 solute carrier family 13 (sodium-dependent dicarboxylate transporter), member 3
SLC22A18AS solute carrier family 22 (organic cation transporter), member 18 antisense
SLC23A2 solute carrier family 23 (ascorbic acid transporter), member 2
SLC2A1 solute carrier family 2 (facilitated glucose transporter), member 1
SLC30A5 solute carrier family 30 (zinc transporter), member 5
SMAD3 SMAD family member 3
SPTB spectrin, beta, erythrocytic
ST8SIA5 ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 5
TAGLN3 transgelin 3
TAPT1 transmembrane anterior posterior transformation 1
TBX6 T-box 6
THBS1 thrombospondin 1
TINF2 TERF1 (TRF1)-interacting nuclear factor 2
TMC7 transmembrane channel-like 7
TMOD1 tropomodulin 1
TRIM29 tripartite motif containing 29
TSC22D3 TSC22 domain family, member 3
TUBA3C tubulin, alpha 3c
VEGFB vascular endothelial growth factor B
VIPR2 vasoactive intestinal peptide receptor 2
WAS Wiskott-Aldrich syndrome
YTHDC2 YTH domain containing 2
ZBTB16 zinc finger and BTB domain containing 16
ZBTB33 zinc finger and BTB domain containing 33

decreased expression

Symbol Name
ADM adrenomedullin
ADRB2 adrenoceptor beta 2, surface
AMIGO2 adhesion molecule with Ig-like domain 2
APBB3 amyloid beta (A4) precursor protein-binding, family B, member 3
ASTE1 asteroid homolog 1 (Drosophila)
ATF3 activating transcription factor 3
BBS1 Bardet-Biedl syndrome 1
BCL2A1 BCL2-related protein A1
BNIP3 BCL2/adenovirus E1B 19kDa interacting protein 3
CA5BP1 carbonic anhydrase VB pseudogene 1
CCL2 chemokine (C-C motif) ligand 2
CD69 CD69 molecule
CDKN1A cyclin-dependent kinase inhibitor 1A (p21, Cip1)
CDKN2D cyclin-dependent kinase inhibitor 2D (p19, inhibits CDK4)
CENPQ centromere protein Q
CFAP44 cilia and flagella associated protein 44
CLGN calmegin
CLK1 CDC-like kinase 1
CSAD cysteine sulfinic acid decarboxylase
CX3CR1 chemokine (C-X3-C motif) receptor 1
CXCL8 chemokine (C-X-C motif) ligand 8
CYTIP cytohesin 1 interacting protein
DHRS3 dehydrogenase/reductase (SDR family) member 3
DNMBP dynamin binding protein
DPY19L2P2 DPY19L2 pseudogene 2
DUSP5 dual specificity phosphatase 5
EGR1 early growth response 1
ENO2 enolase 2 (gamma, neuronal)
ERCC6 excision repair cross-complementation group 6
ETV4 ets variant 4
FAM188A family with sequence similarity 188, member A
FAM53C family with sequence similarity 53, member C
FAM8A1 family with sequence similarity 8, member A1
FBXO3 F-box protein 3
FCGR2B Fc fragment of IgG, low affinity IIb, receptor (CD32)
GATB glutamyl-tRNA(Gln) amidotransferase, subunit B
GPNMB glycoprotein (transmembrane) nmb
HCAR3 hydroxycarboxylic acid receptor 3
HILPDA hypoxia inducible lipid droplet-associated
HIST1H2BI histone cluster 1, H2bi
HIVEP1 human immunodeficiency virus type I enhancer binding protein 1
HOPX HOP homeobox
HRAS Harvey rat sarcoma viral oncogene homolog
HSPA4L heat shock 70kDa protein 4-like
IL1B interleukin 1, beta
IMPACT impact RWD domain protein
ITGA2 integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor)
JUN jun proto-oncogene
KANSL1L KAT8 regulatory NSL complex subunit 1-like
KDM3A lysine (K)-specific demethylase 3A
KLF10 Kruppel-like factor 10
LY75 lymphocyte antigen 75
MAP4K3 mitogen-activated protein kinase kinase kinase kinase 3
MCM9 minichromosome maintenance complex component 9
MED9 mediator complex subunit 9
MKNK2 MAP kinase interacting serine/threonine kinase 2
MOAP1 modulator of apoptosis 1
NDRG1 N-myc downstream regulated 1
NEIL3 nei endonuclease VIII-like 3 (E. coli)
NOL6 nucleolar protein 6 (RNA-associated)
NUPL1 nucleoporin like 1
P4HA1 prolyl 4-hydroxylase, alpha polypeptide I
PCNXL4 pecanex-like 4 (Drosophila)
PFKFB3 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 3
PHACTR1 phosphatase and actin regulator 1
PIM1 Pim-1 proto-oncogene, serine/threonine kinase
PLOD2 procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2
PNOC prepronociceptin
POLM polymerase (DNA directed), mu
PTGS2 prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase)
RAB23 RAB23, member RAS oncogene family
RBM47 RNA binding motif protein 47
RCBTB2 regulator of chromosome condensation (RCC1) and BTB (POZ) domain containing protein 2
RGS13 regulator of G-protein signaling 13
RGS2 regulator of G-protein signaling 2
SCRIB scribbled planar cell polarity protein
SERPINE2 serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2
SLC2A5 solute carrier family 2 (facilitated glucose/fructose transporter), member 5
SLC38A6 solute carrier family 38, member 6
SLC6A8 solute carrier family 6 (neurotransmitter transporter), member 8
SLC9A3R1 solute carrier family 9, subfamily A (NHE3, cation proton antiporter 3), member 3 regulator 1
SLFN12 schlafen family member 12
SND1-IT1 SND1 intronic transcript 1
SP1 Sp1 transcription factor
SPI1 Spi-1 proto-oncogene
SPP1 secreted phosphoprotein 1
THBS4 thrombospondin 4
TMEM45A transmembrane protein 45A
TNRC6B trinucleotide repeat containing 6B
TRAPPC6A trafficking protein particle complex 6A
TRHDE thyrotropin-releasing hormone degrading enzyme
TTC26 tetratricopeptide repeat domain 26
YEATS4 YEATS domain containing 4
ZBTB10 zinc finger and BTB domain containing 10
ZMYM1 zinc finger, MYM-type 1
ZNF10 zinc finger protein 10
ZNF37BP zinc finger protein 37B, pseudogene
ZNF468 zinc finger protein 468
ZNF611 zinc finger protein 611