| Dataset | GeneRIF Biological Term Annotations |
| Category | structural or functional annotations |
| Type | biological term |
| Description | receptor-interacting serine-threonine kinase 3|The product of this gene is a member of the receptor-interacting protein (RIP) family of serine/threonine protein kinases, and contains a C-terminal domain unique from other RIP family members. The encoded protein is predominantly localized to the cytoplasm, and can undergo nucleocytoplasmic shuttling dependent on novel nuclear localization and export signals. It is a component of the tumor necrosis factor (TNF) receptor-I signaling complex, and can induce apoptosis and weakly activate the NF-kappaB transcription factor. [provided by RefSeq, Jul 2008] (NCBI Entrez Gene Database, 11035) |
| Similar Terms | |
| Downloads & Tools |
4 genes co-occuring with the biological term ripk3 in literature-supported statements describing functions of genes from the GeneRIF Biological Term Annotations dataset.
