A protein complex whose core components are the receptor-interacting serine/threonine-protein kinases RIPK1 and RIPK3 (also called RIP1 and RIP3). Formation of the ripoptosome can induce an extrinsic apoptotic signaling pathway or a necroptotic signaling pathway. The composition of this protein complex may depend on several factors including nature of the signal, cell type and more. (Gene Ontology, GO_0097342)
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7 proteins localized to the ripoptosome cellular component from the COMPARTMENTS Curated Protein Localization Evidence Scores dataset.
