ripoptosome Gene Set

Dataset	COMPARTMENTS Text-mining Protein Localization Evidence Scores
Category	structural or functional annotations
Type	cellular component
Description	A protein complex whose core components are the receptor-interacting serine/threonine-protein kinases RIPK1 and RIPK3 (also called RIP1 and RIP3). Formation of the ripoptosome can induce an extrinsic apoptotic signaling pathway or a necroptotic signaling pathway. The composition of this protein complex may depend on several factors including nature of the signal, cell type and more. (Gene Ontology, GO_0097342)
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Genes

19 proteins co-occuring with the ripoptosome cellular component in abstracts of biomedical publications from the COMPARTMENTS Text-mining Protein Localization Evidence Scores dataset.

Symbol	Name	Standardized Value
BIRC2	baculoviral IAP repeat containing 2	1.21376
BIRC3	baculoviral IAP repeat containing 3	1.1952
RIPK1	receptor (TNFRSF)-interacting serine-threonine kinase 1	1.17004
FADD	Fas (TNFRSF6)-associated via death domain	1.15774
CASP8	caspase 8, apoptosis-related cysteine peptidase	1.11276
MLKL	mixed lineage kinase domain-like	0.955917
DIABLO	diablo, IAP-binding mitochondrial protein	0.93596
XIAP	X-linked inhibitor of apoptosis, E3 ubiquitin protein ligase	0.93596
CFLAR	CASP8 and FADD-like apoptosis regulator	0.867206
RIPK3	receptor-interacting serine-threonine kinase 3	0.823582
TNFRSF1A	tumor necrosis factor receptor superfamily, member 1A	0.640145
CASP10	caspase 10, apoptosis-related cysteine peptidase	0.580504
TLR3	toll-like receptor 3	0.528798
TRADD	TNFRSF1A-associated via death domain	0.446862
FASLG	Fas ligand (TNF superfamily, member 6)	0.355563
TNF	tumor necrosis factor	0.265677
ATG7	autophagy related 7	0.262755
NLRP3	NLR family, pyrin domain containing 3	0.246046
PPIF	peptidylprolyl isomerase F	0.21646