risc complex Gene Set

Dataset COMPARTMENTS Curated Protein Localization Evidence Scores
Category structural or functional annotations
Type cellular component
Description A ribonucleoprotein complex that contains members of the Argonaute family of proteins, small interfering RNAs (siRNAs) or microRNAs (miRNAs), and miRNA or siRNA-complementary mRNAs, in addition to a number of accessory factors. The RISC complex is involved in posttranscriptional repression of gene expression through downregulation of translation or induction of mRNA degradation. (Gene Ontology, GO_0016442)
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10 proteins localized to the risc complex cellular component from the COMPARTMENTS Curated Protein Localization Evidence Scores dataset.

Symbol Name Standardized Value
DCP2 decapping mRNA 2 0.663342
EIF4E eukaryotic translation initiation factor 4E 0.663342
DICER1 dicer 1, ribonuclease type III 0.663342
LIMD1 LIM domains containing 1 0.663342
DDX6 DEAD (Asp-Glu-Ala-Asp) box helicase 6 0.663342
TARBP2 TAR (HIV-1) RNA binding protein 2 0.663342
AGO2 argonaute RISC catalytic component 2 0.663342
AGO3 argonaute RISC catalytic component 3 0.03318
AGO4 argonaute RISC catalytic component 4 0.03318
SND1 staphylococcal nuclease and tudor domain containing 1 0.03318