risperidone-2947 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

199 genes differentially expressed following the risperidone-2947 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ACACB acetyl-CoA carboxylase beta
ADAMTS5 ADAM metallopeptidase with thrombospondin type 1 motif, 5
AIMP2 aminoacyl tRNA synthetase complex-interacting multifunctional protein 2
ARHGAP26 Rho GTPase activating protein 26
ATF7IP activating transcription factor 7 interacting protein
AURKA aurora kinase A
BMP8A bone morphogenetic protein 8a
CACNB3 calcium channel, voltage-dependent, beta 3 subunit
CDKL1 cyclin-dependent kinase-like 1 (CDC2-related kinase)
CELSR3 cadherin, EGF LAG seven-pass G-type receptor 3
CEP250 centrosomal protein 250kDa
CHD9 chromodomain helicase DNA binding protein 9
CNOT4 CCR4-NOT transcription complex, subunit 4
CNTD2 cyclin N-terminal domain containing 2
COX6A2 cytochrome c oxidase subunit VIa polypeptide 2
CPNE7 copine VII
CRABP2 cellular retinoic acid binding protein 2
CUX2 cut-like homeobox 2
DCAF13 DDB1 and CUL4 associated factor 13
DDR1-AS1 DDR1 antisense RNA 1 (head to head)
DMP1 dentin matrix acidic phosphoprotein 1
DMRT1 doublesex and mab-3 related transcription factor 1
DOK3 docking protein 3
E2F4 E2F transcription factor 4, p107/p130-binding
ELN elastin
EPN2 epsin 2
EXTL3 exostosin-like glycosyltransferase 3
FLRT1 fibronectin leucine rich transmembrane protein 1
FRMD1 FERM domain containing 1
FSTL3 follistatin-like 3 (secreted glycoprotein)
GALNT10 polypeptide N-acetylgalactosaminyltransferase 10
GALNT3 polypeptide N-acetylgalactosaminyltransferase 3
GATM glycine amidinotransferase (L-arginine:glycine amidinotransferase)
GCFC2 GC-rich sequence DNA-binding factor 2
GPR15 G protein-coupled receptor 15
HOXD1 homeobox D1
HSPA2 heat shock 70kDa protein 2
ICAM1 intercellular adhesion molecule 1
IDH3G isocitrate dehydrogenase 3 (NAD+) gamma
IDUA iduronidase, alpha-L-
IGFBP2 insulin-like growth factor binding protein 2, 36kDa
IGL immunoglobulin lambda locus
IGLL3P immunoglobulin lambda-like polypeptide 3, pseudogene
IL12RB1 interleukin 12 receptor, beta 1
INO80B INO80 complex subunit B
KCNS1 potassium voltage-gated channel, modifier subfamily S, member 1
KIF17 kinesin family member 17
KIF1A kinesin family member 1A
KIF5C kinesin family member 5C
LMNA lamin A/C
LOC100287590 uncharacterized LOC100287590
LRRC75B leucine rich repeat containing 75B
LSM4 LSM4 homolog, U6 small nuclear RNA associated (S. cerevisiae)
MED14 mediator complex subunit 14
MEFV Mediterranean fever
MLLT3 myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 3
MLLT4 myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 4
MR1 major histocompatibility complex, class I-related
MTA1 metastasis associated 1
MUL1 mitochondrial E3 ubiquitin protein ligase 1
MYH10 myosin, heavy chain 10, non-muscle
NFKBIB nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, beta
NOL12 nucleolar protein 12
NRP1 neuropilin 1
NSUN6 NOP2/Sun domain family, member 6
NUP88 nucleoporin 88kDa
PDLIM2 PDZ and LIM domain 2 (mystique)
PDPN podoplanin
PIGQ phosphatidylinositol glycan anchor biosynthesis, class Q
PKNOX1 PBX/knotted 1 homeobox 1
PQLC2 PQ loop repeat containing 2
PRLR prolactin receptor
PSG4 pregnancy specific beta-1-glycoprotein 4
RAB2A RAB2A, member RAS oncogene family
RAB6A RAB6A, member RAS oncogene family
RAD54L2 RAD54-like 2 (S. cerevisiae)
RASGRP2 RAS guanyl releasing protein 2 (calcium and DAG-regulated)
RPS6KA4 ribosomal protein S6 kinase, 90kDa, polypeptide 4
RSU1 Ras suppressor protein 1
RYR1 ryanodine receptor 1 (skeletal)
SIKE1 suppressor of IKBKE 1
SLC10A3 solute carrier family 10, member 3
SLC15A3 solute carrier family 15 (oligopeptide transporter), member 3
SLC44A1 solute carrier family 44 (choline transporter), member 1
SNRNP200 small nuclear ribonucleoprotein 200kDa (U5)
SNX13 sorting nexin 13
SOX12 SRY (sex determining region Y)-box 12
TBRG4 transforming growth factor beta regulator 4
TFR2 transferrin receptor 2
TGFBR1 transforming growth factor, beta receptor 1
TMEM212 transmembrane protein 212
TMEM63A transmembrane protein 63A
TRABD TraB domain containing
TRIM16 tripartite motif containing 16
UPK3B uroplakin 3B
VPS13B vacuolar protein sorting 13 homolog B (yeast)
XIAP X-linked inhibitor of apoptosis, E3 ubiquitin protein ligase
ZBTB22 zinc finger and BTB domain containing 22
ZNF492 zinc finger protein 492

decreased expression

Symbol Name
ABCB4 ATP-binding cassette, sub-family B (MDR/TAP), member 4
ABHD4 abhydrolase domain containing 4
AEN apoptosis enhancing nuclease
AOAH acyloxyacyl hydrolase (neutrophil)
APH1B APH1B gamma secretase subunit
ARFGAP1 ADP-ribosylation factor GTPase activating protein 1
ARID5A AT rich interactive domain 5A (MRF1-like)
ASGR2 asialoglycoprotein receptor 2
ATG9A autophagy related 9A
BBS10 Bardet-Biedl syndrome 10
C1ORF21 chromosome 1 open reading frame 21
C2CD2 C2 calcium-dependent domain containing 2
C3 complement component 3
C8ORF60 chromosome 8 open reading frame 60
CCDC69 coiled-coil domain containing 69
CEL carboxyl ester lipase
CEP295 centrosomal protein 295kDa
DDB2 damage-specific DNA binding protein 2, 48kDa
DENND1C DENN/MADD domain containing 1C
DENND4C DENN/MADD domain containing 4C
DHX35 DEAH (Asp-Glu-Ala-His) box polypeptide 35
DNA2 DNA replication helicase/nuclease 2
DOK2 docking protein 2, 56kDa
DUSP2 dual specificity phosphatase 2
DUSP4 dual specificity phosphatase 4
EEF2KMT eukaryotic elongation factor 2 lysine methyltransferase
ENAH enabled homolog (Drosophila)
EPHA4 EPH receptor A4
ERMAP erythroblast membrane-associated protein (Scianna blood group)
FAM172A family with sequence similarity 172, member A
FPGS folylpolyglutamate synthase
GJA1 gap junction protein, alpha 1, 43kDa
GPNMB glycoprotein (transmembrane) nmb
GPR137B G protein-coupled receptor 137B
HCAR3 hydroxycarboxylic acid receptor 3
HHLA3 HERV-H LTR-associating 3
HIST1H2AJ histone cluster 1, H2aj
HSPA6 heat shock 70kDa protein 6 (HSP70B')
IFI6 interferon, alpha-inducible protein 6
IFNAR1 interferon (alpha, beta and omega) receptor 1
IL11RA interleukin 11 receptor, alpha
ING4 inhibitor of growth family, member 4
IP6K1 inositol hexakisphosphate kinase 1
IPPK inositol 1,3,4,5,6-pentakisphosphate 2-kinase
ITGA2 integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor)
ITGAX integrin, alpha X (complement component 3 receptor 4 subunit)
KIAA1107 KIAA1107
LRP3 low density lipoprotein receptor-related protein 3
MAP4K3 mitogen-activated protein kinase kinase kinase kinase 3
MED22 mediator complex subunit 22
MKNK2 MAP kinase interacting serine/threonine kinase 2
MRPL44 mitochondrial ribosomal protein L44
MTCP1 mature T-cell proliferation 1
MYO19 myosin XIX
NARFL nuclear prelamin A recognition factor-like
OTUD3 OTU deubiquitinase 3
PDZD8 PDZ domain containing 8
PIAS3 protein inhibitor of activated STAT, 3
PITPNM1 phosphatidylinositol transfer protein, membrane-associated 1
PLOD1 procollagen-lysine, 2-oxoglutarate 5-dioxygenase 1
PLOD2 procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2
PNOC prepronociceptin
POMT1 protein-O-mannosyltransferase 1
PPFIA4 protein tyrosine phosphatase, receptor type, f polypeptide (PTPRF), interacting protein (liprin), alpha 4
PSKH1 protein serine kinase H1
RAB33B RAB33B, member RAS oncogene family
RABL6 RAB, member RAS oncogene family-like 6
RECQL4 RecQ protein-like 4
RGS13 regulator of G-protein signaling 13
RHBDF1 rhomboid 5 homolog 1 (Drosophila)
RHOH ras homolog family member H
RPL23AP7 ribosomal protein L23a pseudogene 7
SALL2 spalt-like transcription factor 2
SCAMP4 secretory carrier membrane protein 4
SCD5 stearoyl-CoA desaturase 5
SLC25A10 solute carrier family 25 (mitochondrial carrier; dicarboxylate transporter), member 10
SLC29A3 solute carrier family 29 (equilibrative nucleoside transporter), member 3
SMYD5 SMYD family member 5
SPIDR scaffolding protein involved in DNA repair
STON1 stonin 1
STX17 syntaxin 17
SYNGR2 synaptogyrin 2
TMEM158 transmembrane protein 158 (gene/pseudogene)
TMEM45A transmembrane protein 45A
TNFRSF10D tumor necrosis factor receptor superfamily, member 10d, decoy with truncated death domain
TNRC6B trinucleotide repeat containing 6B
TPCN1 two pore segment channel 1
TRIM36 tripartite motif containing 36
TRPC4AP transient receptor potential cation channel, subfamily C, member 4 associated protein
UPP1 uridine phosphorylase 1
USP11 ubiquitin specific peptidase 11
VPS8 vacuolar protein sorting 8 homolog (S. cerevisiae)
XYLT2 xylosyltransferase II
YY2 YY2 transcription factor
ZFP30 ZFP30 zinc finger protein
ZNF134 zinc finger protein 134
ZNF282 zinc finger protein 282
ZNF468 zinc finger protein 468
ZNF506 zinc finger protein 506
ZNF862 zinc finger protein 862