risperidone-3508 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

196 genes differentially expressed following the risperidone-3508 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ADAM22 ADAM metallopeptidase domain 22
ADORA3 adenosine A3 receptor
AK2 adenylate kinase 2
ALDH1A3 aldehyde dehydrogenase 1 family, member A3
ALDH3B1 aldehyde dehydrogenase 3 family, member B1
ALS2CL ALS2 C-terminal like
AP1S1 adaptor-related protein complex 1, sigma 1 subunit
AP2B1 adaptor-related protein complex 2, beta 1 subunit
ARMC4 armadillo repeat containing 4
ARTN artemin
ATAT1 alpha tubulin acetyltransferase 1
ATF6B activating transcription factor 6 beta
ATP2B4 ATPase, Ca++ transporting, plasma membrane 4
BMP6 bone morphogenetic protein 6
BTD biotinidase
CABYR calcium binding tyrosine-(Y)-phosphorylation regulated
CACNA2D2 calcium channel, voltage-dependent, alpha 2/delta subunit 2
CBL Cbl proto-oncogene, E3 ubiquitin protein ligase
CD82 CD82 molecule
CDKN2D cyclin-dependent kinase inhibitor 2D (p19, inhibits CDK4)
CDRT1 CMT1A duplicated region transcript 1
CFAP45 cilia and flagella associated protein 45
CLEC11A C-type lectin domain family 11, member A
CLMN calmin (calponin-like, transmembrane)
CRHR2 corticotropin releasing hormone receptor 2
CRIP1 cysteine-rich protein 1 (intestinal)
CRMP1 collapsin response mediator protein 1
CYP1A1 cytochrome P450, family 1, subfamily A, polypeptide 1
CYP1B1 cytochrome P450, family 1, subfamily B, polypeptide 1
DCAKD dephospho-CoA kinase domain containing
DDIT3 DNA-damage-inducible transcript 3
DOCK6 dedicator of cytokinesis 6
DTX2P1-UPK3BP1-PMS2P11 DTX2P1-UPK3BP1-PMS2P11 readthrough transcribed pseudogene
ENTPD4 ectonucleoside triphosphate diphosphohydrolase 4
ETNK2 ethanolamine kinase 2
ETV6 ets variant 6
FOXI1 forkhead box I1
GABRR2 gamma-aminobutyric acid (GABA) A receptor, rho 2
GLYR1 glyoxylate reductase 1 homolog (Arabidopsis)
GOSR1 golgi SNAP receptor complex member 1
GSPT1 G1 to S phase transition 1
HIST1H4C histone cluster 1, H4c
IFT140 intraflagellar transport 140
IGLJ3 immunoglobulin lambda joining 3
IL5RA interleukin 5 receptor, alpha
ITPR1 inositol 1,4,5-trisphosphate receptor, type 1
KATNB1 katanin p80 (WD repeat containing) subunit B 1
KCTD17 potassium channel tetramerization domain containing 17
KMT2A lysine (K)-specific methyltransferase 2A
LAMB3 laminin, beta 3
LIMCH1 LIM and calponin homology domains 1
MALT1 MALT1 paracaspase
MARS methionyl-tRNA synthetase
MDM2 MDM2 proto-oncogene, E3 ubiquitin protein ligase
MTMR3 myotubularin related protein 3
MUC1 mucin 1, cell surface associated
MYL4 myosin, light chain 4, alkali; atrial, embryonic
MYO1C myosin IC
NF2 neurofibromin 2 (merlin)
NFATC1 nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 1
NOX5 NADPH oxidase, EF-hand calcium binding domain 5
OAS3 2'-5'-oligoadenylate synthetase 3, 100kDa
OR12D2 olfactory receptor, family 12, subfamily D, member 2 (gene/pseudogene)
ORAI2 ORAI calcium release-activated calcium modulator 2
PIP5K1A phosphatidylinositol-4-phosphate 5-kinase, type I, alpha
PLCB1 phospholipase C, beta 1 (phosphoinositide-specific)
PLEKHA2 pleckstrin homology domain containing, family A (phosphoinositide binding specific) member 2
PLEKHF1 pleckstrin homology domain containing, family F (with FYVE domain) member 1
PLSCR3 phospholipid scramblase 3
POU2F3 POU class 2 homeobox 3
PPP3R1 protein phosphatase 3, regulatory subunit B, alpha
PXN paxillin
RAD50 RAD50 homolog (S. cerevisiae)
RARG retinoic acid receptor, gamma
REL v-rel avian reticuloendotheliosis viral oncogene homolog
RELB v-rel avian reticuloendotheliosis viral oncogene homolog B
RHOT2 ras homolog family member T2
RPH3AL rabphilin 3A-like (without C2 domains)
SDC3 syndecan 3
SELL selectin L
SETD1A SET domain containing 1A
SLC35D1 solute carrier family 35 (UDP-GlcA/UDP-GalNAc transporter), member D1
SOX4 SRY (sex determining region Y)-box 4
SPDEF SAM pointed domain containing ETS transcription factor
SPRY4 sprouty homolog 4 (Drosophila)
SVIL supervillin
TAF6L TAF6-like RNA polymerase II, p300/CBP-associated factor (PCAF)-associated factor, 65kDa
TLK1 tousled-like kinase 1
TMC6 transmembrane channel-like 6
TNFRSF4 tumor necrosis factor receptor superfamily, member 4
TONSL tonsoku-like, DNA repair protein
TREX1 three prime repair exonuclease 1
TSC2 tuberous sclerosis 2
UTRN utrophin
ZC3H13 zinc finger CCCH-type containing 13
ZCCHC11 zinc finger, CCHC domain containing 11
ZNF609 zinc finger protein 609
ZNF816 zinc finger protein 816

decreased expression

Symbol Name
ABCC4 ATP-binding cassette, sub-family C (CFTR/MRP), member 4
ABI3BP ABI family, member 3 (NESH) binding protein
ACSBG2 acyl-CoA synthetase bubblegum family member 2
ACSL4 acyl-CoA synthetase long-chain family member 4
ADGRE5 adhesion G protein-coupled receptor E5
ADGRG2 adhesion G protein-coupled receptor G2
ANKRD2 ankyrin repeat domain 2 (stretch responsive muscle)
APOBEC2 apolipoprotein B mRNA editing enzyme, catalytic polypeptide-like 2
ASPN asporin
BANK1 B-cell scaffold protein with ankyrin repeats 1
BEGAIN brain-enriched guanylate kinase-associated
C10ORF95 chromosome 10 open reading frame 95
C22ORF46 chromosome 22 open reading frame 46
C9ORF9 chromosome 9 open reading frame 9
CAPN5 calpain 5
CASZ1 castor zinc finger 1
CCDC121 coiled-coil domain containing 121
CCDC25 coiled-coil domain containing 25
CENPO centromere protein O
CIDEB cell death-inducing DFFA-like effector b
CINP cyclin-dependent kinase 2 interacting protein
CLEC16A C-type lectin domain family 16, member A
COX6A2 cytochrome c oxidase subunit VIa polypeptide 2
CUZD1 CUB and zona pellucida-like domains 1
DAGLA diacylglycerol lipase, alpha
DDX54 DEAD (Asp-Glu-Ala-Asp) box polypeptide 54
DOC2A double C2-like domains, alpha
EMID1 EMI domain containing 1
FABP6 fatty acid binding protein 6, ileal
FAM160B2 family with sequence similarity 160, member B2
FANCE Fanconi anemia, complementation group E
FLT4 fms-related tyrosine kinase 4
FRS2 fibroblast growth factor receptor substrate 2
FSTL3 follistatin-like 3 (secreted glycoprotein)
GABRB2 gamma-aminobutyric acid (GABA) A receptor, beta 2
GLS2 glutaminase 2 (liver, mitochondrial)
GNAT2 guanine nucleotide binding protein (G protein), alpha transducing activity polypeptide 2
GSTCD glutathione S-transferase, C-terminal domain containing
GTPBP2 GTP binding protein 2
HIST1H2AJ histone cluster 1, H2aj
HIST1H2BO histone cluster 1, H2bo
HIST2H2AA3 histone cluster 2, H2aa3
HNRNPA3P1 heterogeneous nuclear ribonucleoprotein A3 pseudogene 1
INO80D INO80 complex subunit D
IRF2BP1 interferon regulatory factor 2 binding protein 1
KLF3 Kruppel-like factor 3 (basic)
LAX1 lymphocyte transmembrane adaptor 1
LHX1 LIM homeobox 1
LHX6 LIM homeobox 6
LIG4 ligase IV, DNA, ATP-dependent
LIN7A lin-7 homolog A (C. elegans)
LOC202181 SUMO-interacting motifs containing 1 pseudogene
LOC730101 uncharacterized LOC730101
MAGEA6 melanoma antigen family A6
MGC12488
MMP15 matrix metallopeptidase 15 (membrane-inserted)
MMP2 matrix metallopeptidase 2
MT1H metallothionein 1H
NACA2 nascent polypeptide-associated complex alpha subunit 2
NKX3-2 NK3 homeobox 2
NPFFR1 neuropeptide FF receptor 1
NPTX1 neuronal pentraxin I
NT5DC3 5'-nucleotidase domain containing 3
NUDT18 nudix (nucleoside diphosphate linked moiety X)-type motif 18
ONECUT2 one cut homeobox 2
OR7E156P olfactory receptor, family 7, subfamily E, member 156 pseudogene
OTUB2 OTU deubiquitinase, ubiquitin aldehyde binding 2
OVGP1 oviductal glycoprotein 1, 120kDa
PDE8B phosphodiesterase 8B
POLR1B polymerase (RNA) I polypeptide B, 128kDa
PRR14L proline rich 14-like
RASL11B RAS-like, family 11, member B
RNF126P1 ring finger protein 126 pseudogene 1
RNF19A ring finger protein 19A, RBR E3 ubiquitin protein ligase
RPAP1 RNA polymerase II associated protein 1
SEMA6D sema domain, transmembrane domain (TM), and cytoplasmic domain, (semaphorin) 6D
SLMO1 slowmo homolog 1 (Drosophila)
SP1 Sp1 transcription factor
TCP10 t-complex 10
TCTN2 tectonic family member 2
TMLHE trimethyllysine hydroxylase, epsilon
TSC22D4 TSC22 domain family, member 4
TUBA3D tubulin, alpha 3d
UBQLN4 ubiquilin 4
ULBP2 UL16 binding protein 2
VEGFC vascular endothelial growth factor C
WLS wntless Wnt ligand secretion mediator
ZBTB39 zinc finger and BTB domain containing 39
ZCWPW1 zinc finger, CW type with PWWP domain 1
ZNF205 zinc finger protein 205
ZNF250 zinc finger protein 250
ZNF324 zinc finger protein 324
ZNF37BP zinc finger protein 37B, pseudogene
ZNF586 zinc finger protein 586
ZNF639 zinc finger protein 639
ZNF652 zinc finger protein 652
ZNF701 zinc finger protein 701
ZNF750 zinc finger protein 750