ritodrine-1280 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

200 genes differentially expressed following the ritodrine-1280 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ABHD3 abhydrolase domain containing 3
ADAM10 ADAM metallopeptidase domain 10
AKAP13 A kinase (PRKA) anchor protein 13
AP1S1 adaptor-related protein complex 1, sigma 1 subunit
ARIH2 ariadne RBR E3 ubiquitin protein ligase 2
ARL4C ADP-ribosylation factor-like 4C
ASAP1 ArfGAP with SH3 domain, ankyrin repeat and PH domain 1
ATP13A3 ATPase type 13A3
B4GALT4 UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 4
BBS4 Bardet-Biedl syndrome 4
BRIP1 BRCA1 interacting protein C-terminal helicase 1
C6ORF62 chromosome 6 open reading frame 62
CALU calumenin
CCNE2 cyclin E2
CD86 CD86 molecule
CDADC1 cytidine and dCMP deaminase domain containing 1
CDK2 cyclin-dependent kinase 2
CHN2 chimerin 2
CSRP2 cysteine and glycine-rich protein 2
CTAGE9 CTAGE family, member 9
DDX3X DEAD (Asp-Glu-Ala-Asp) box helicase 3, X-linked
DOCK4 dedicator of cytokinesis 4
DSTYK dual serine/threonine and tyrosine protein kinase
DTNA dystrobrevin, alpha
DUSP4 dual specificity phosphatase 4
EEF1D eukaryotic translation elongation factor 1 delta (guanine nucleotide exchange protein)
EIF4EBP2 eukaryotic translation initiation factor 4E binding protein 2
EMILIN2 elastin microfibril interfacer 2
ERO1L ERO1-like (S. cerevisiae)
FAM131A family with sequence similarity 131, member A
FAM13A family with sequence similarity 13, member A
FAS Fas cell surface death receptor
FCF1 FCF1 rRNA-processing protein
FGFR1OP FGFR1 oncogene partner
FKBPL FK506 binding protein like
FTH1 ferritin, heavy polypeptide 1
GNA13 guanine nucleotide binding protein (G protein), alpha 13
GNG11 guanine nucleotide binding protein (G protein), gamma 11
HCFC1R1 host cell factor C1 regulator 1 (XPO1 dependent)
HERC4 HECT and RLD domain containing E3 ubiquitin protein ligase 4
IDS iduronate 2-sulfatase
IFI30 interferon, gamma-inducible protein 30
IL1B interleukin 1, beta
IL1RAP interleukin 1 receptor accessory protein
IL1RN interleukin 1 receptor antagonist
ISG20 interferon stimulated exonuclease gene 20kDa
ITGAV integrin, alpha V
ITM2B integral membrane protein 2B
KYNU kynureninase
MAP3K2 mitogen-activated protein kinase kinase kinase 2
MEF2C myocyte enhancer factor 2C
MGEA5 meningioma expressed antigen 5 (hyaluronidase)
MID1 midline 1
NCBP1 nuclear cap binding protein subunit 1, 80kDa
NCOA3 nuclear receptor coactivator 3
NEK2 NIMA-related kinase 2
NEK9 NIMA-related kinase 9
NFYA nuclear transcription factor Y, alpha
NR4A1 nuclear receptor subfamily 4, group A, member 1
NR4A2 nuclear receptor subfamily 4, group A, member 2
NR4A3 nuclear receptor subfamily 4, group A, member 3
NXT2 nuclear transport factor 2-like export factor 2
OASL 2'-5'-oligoadenylate synthetase-like
OPA3 optic atrophy 3 (autosomal recessive, with chorea and spastic paraplegia)
PAPOLA poly(A) polymerase alpha
PCGF2 polycomb group ring finger 2
PDE3B phosphodiesterase 3B, cGMP-inhibited
PDE4B phosphodiesterase 4B, cAMP-specific
PFDN1 prefoldin subunit 1
PIP5K1A phosphatidylinositol-4-phosphate 5-kinase, type I, alpha
PLK4 polo-like kinase 4
PLSCR1 phospholipid scramblase 1
PRKAR1A protein kinase, cAMP-dependent, regulatory, type I, alpha
PRKD3 protein kinase D3
PRNP prion protein
PSEN1 presenilin 1
QKI QKI, KH domain containing, RNA binding
SAP30 Sin3A-associated protein, 30kDa
SAT1 spermidine/spermine N1-acetyltransferase 1
SCAMP1 secretory carrier membrane protein 1
SDC2 syndecan 2
SEC23A Sec23 homolog A (S. cerevisiae)
SGPL1 sphingosine-1-phosphate lyase 1
SLITRK5 SLIT and NTRK-like family, member 5
SNAP23 synaptosomal-associated protein, 23kDa
STAG3L4 stromal antigen 3-like 4 (pseudogene)
STRN3 striatin, calmodulin binding protein 3
STX6 syntaxin 6
THBS1 thrombospondin 1
TMEM134 transmembrane protein 134
TNFRSF12A tumor necrosis factor receptor superfamily, member 12A
TNFRSF21 tumor necrosis factor receptor superfamily, member 21
TPR translocated promoter region, nuclear basket protein
TRIM23 tripartite motif containing 23
TXNL4A thioredoxin-like 4A
VCAN versican
VDAC3 voltage-dependent anion channel 3
WDR33 WD repeat domain 33
WDR59 WD repeat domain 59
ZNF45 zinc finger protein 45

decreased expression

Symbol Name
ACAD10 acyl-CoA dehydrogenase family, member 10
ADTRP androgen-dependent TFPI-regulating protein
AGPAT3 1-acylglycerol-3-phosphate O-acyltransferase 3
AIM2 absent in melanoma 2
AP4M1 adaptor-related protein complex 4, mu 1 subunit
APH1B APH1B gamma secretase subunit
ARHGEF1 Rho guanine nucleotide exchange factor (GEF) 1
ARHGEF10L Rho guanine nucleotide exchange factor (GEF) 10-like
ARMC6 armadillo repeat containing 6
ATP8B1 ATPase, aminophospholipid transporter, class I, type 8B, member 1
BATF basic leucine zipper transcription factor, ATF-like
BBC3 BCL2 binding component 3
BRAF B-Raf proto-oncogene, serine/threonine kinase
BZRAP1 benzodiazepine receptor (peripheral) associated protein 1
C11ORF95 chromosome 11 open reading frame 95
C14ORF159 chromosome 14 open reading frame 159
C19ORF24 chromosome 19 open reading frame 24
C5ORF45 chromosome 5 open reading frame 45
CAD carbamoyl-phosphate synthetase 2, aspartate transcarbamylase, and dihydroorotase
CAPN15 calpain 15
CCDC86 coiled-coil domain containing 86
CD3D CD3d molecule, delta (CD3-TCR complex)
CEP170B centrosomal protein 170B
CHKB choline kinase beta
CORO2A coronin, actin binding protein, 2A
CORO7 coronin 7
CPPED1 calcineurin-like phosphoesterase domain containing 1
DDX31 DEAD (Asp-Glu-Ala-Asp) box polypeptide 31
DEAF1 DEAF1 transcription factor
DFFB DNA fragmentation factor, 40kDa, beta polypeptide (caspase-activated DNase)
DHRS9 dehydrogenase/reductase (SDR family) member 9
DNAJC17 DnaJ (Hsp40) homolog, subfamily C, member 17
EEF1A2 eukaryotic translation elongation factor 1 alpha 2
FCHO1 FCH domain only 1
FES FES proto-oncogene, tyrosine kinase
FILIP1L filamin A interacting protein 1-like
FOSL1 FOS-like antigen 1
FURIN furin (paired basic amino acid cleaving enzyme)
GRWD1 glutamate-rich WD repeat containing 1
GTF2IRD1 GTF2I repeat domain containing 1
HDAC9 histone deacetylase 9
IFITM3 interferon induced transmembrane protein 3
IPO4 importin 4
IRF8 interferon regulatory factor 8
KCTD7 potassium channel tetramerization domain containing 7
L2HGDH L-2-hydroxyglutarate dehydrogenase
MED24 mediator complex subunit 24
MLC1 megalencephalic leukoencephalopathy with subcortical cysts 1
MRPS34 mitochondrial ribosomal protein S34
MYL5 myosin, light chain 5, regulatory
N4BP2L2-IT2 N4BPL2 intronic transcript 2
NMB neuromedin B
NPDC1 neural proliferation, differentiation and control, 1
NRGN neurogranin (protein kinase C substrate, RC3)
NSMF NMDA receptor synaptonuclear signaling and neuronal migration factor
NUBP2 nucleotide binding protein 2
PCOLCE2 procollagen C-endopeptidase enhancer 2
PCYT2 phosphate cytidylyltransferase 2, ethanolamine
PLCB3 phospholipase C, beta 3 (phosphatidylinositol-specific)
PNPLA6 patatin-like phospholipase domain containing 6
POLR3D polymerase (RNA) III (DNA directed) polypeptide D, 44kDa
PRKCSH protein kinase C substrate 80K-H
PYCR1 pyrroline-5-carboxylate reductase 1
RAD54L2 RAD54-like 2 (S. cerevisiae)
RHOBTB1 Rho-related BTB domain containing 1
RPL23AP32 ribosomal protein L23a pseudogene 32
RSAD1 radical S-adenosyl methionine domain containing 1
S1PR4 sphingosine-1-phosphate receptor 4
SCML2 sex comb on midleg-like 2 (Drosophila)
SCRIB scribbled planar cell polarity protein
SEMA4A sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4A
SHPK sedoheptulokinase
SLC12A9 solute carrier family 12, member 9
SLC17A9 solute carrier family 17 (vesicular nucleotide transporter), member 9
SLC25A22 solute carrier family 25 (mitochondrial carrier: glutamate), member 22
SLC29A2 solute carrier family 29 (equilibrative nucleoside transporter), member 2
SLC39A14 solute carrier family 39 (zinc transporter), member 14
SLPI secretory leukocyte peptidase inhibitor
STAG3L1 stromal antigen 3-like 1 (pseudogene)
STAR steroidogenic acute regulatory protein
TCTA T-cell leukemia translocation altered
TERT telomerase reverse transcriptase
THEM6 thioesterase superfamily member 6
THOP1 thimet oligopeptidase 1
TINF2 TERF1 (TRF1)-interacting nuclear factor 2
TMEM120B transmembrane protein 120B
TNNT1 troponin T type 1 (skeletal, slow)
TPRA1 transmembrane protein, adipocyte asscociated 1
TRMT2A tRNA methyltransferase 2 homolog A (S. cerevisiae)
TRPC4AP transient receptor potential cation channel, subfamily C, member 4 associated protein
TUBA3C tubulin, alpha 3c
ULK1 unc-51 like autophagy activating kinase 1
UPB1 ureidopropionase, beta
USB1 U6 snRNA biogenesis 1
VSIG4 V-set and immunoglobulin domain containing 4
WT1-AS WT1 antisense RNA
XPC xeroderma pigmentosum, complementation group C
ZBTB44 zinc finger and BTB domain containing 44
ZNF248 zinc finger protein 248
ZNF701 zinc finger protein 701