ritodrine-5680 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

194 genes differentially expressed following the ritodrine-5680 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ACOT11 acyl-CoA thioesterase 11
ACRV1 acrosomal vesicle protein 1
ADAM11 ADAM metallopeptidase domain 11
ADAM22 ADAM metallopeptidase domain 22
ADGRA2 adhesion G protein-coupled receptor A2
ADORA3 adenosine A3 receptor
AGER advanced glycosylation end product-specific receptor
AKR1C1 aldo-keto reductase family 1, member C1
AMPD3 adenosine monophosphate deaminase 3
ARHGEF6 Rac/Cdc42 guanine nucleotide exchange factor (GEF) 6
BET1L Bet1 golgi vesicular membrane trafficking protein-like
CCL27 chemokine (C-C motif) ligand 27
CDC25A cell division cycle 25A
CDH4 cadherin 4, type 1, R-cadherin (retinal)
CDKN2D cyclin-dependent kinase inhibitor 2D (p19, inhibits CDK4)
CENPO centromere protein O
CEP250 centrosomal protein 250kDa
CHRNA2 cholinergic receptor, nicotinic, alpha 2 (neuronal)
CLCN4 chloride channel, voltage-sensitive 4
CLEC7A C-type lectin domain family 7, member A
CREBZF CREB/ATF bZIP transcription factor
CRTC1 CREB regulated transcription coactivator 1
CXXC4 CXXC finger protein 4
CYP4B1 cytochrome P450, family 4, subfamily B, polypeptide 1
DCHS2 dachsous cadherin-related 2
DENND1C DENN/MADD domain containing 1C
DPY19L1P1 DPY19L1 pseudogene 1
EDNRA endothelin receptor type A
EDNRB endothelin receptor type B
EGFR epidermal growth factor receptor
FBLN1 fibulin 1
FCER1G Fc fragment of IgE, high affinity I, receptor for; gamma polypeptide
FHL1 four and a half LIM domains 1
FOXN3 forkhead box N3
GABRA2 gamma-aminobutyric acid (GABA) A receptor, alpha 2
GAL3ST4 galactose-3-O-sulfotransferase 4
GAP43 growth associated protein 43
GLI1 GLI family zinc finger 1
GPR21 G protein-coupled receptor 21
GSN gelsolin
GUCA2B guanylate cyclase activator 2B (uroguanylin)
HNF1A HNF1 homeobox A
HOXA7 homeobox A7
ICOSLG inducible T-cell co-stimulator ligand
IDUA iduronidase, alpha-L-
IQCA1 IQ motif containing with AAA domain 1
IRF2BP1 interferon regulatory factor 2 binding protein 1
KCNJ4 potassium channel, inwardly rectifying subfamily J, member 4
KIAA1045 KIAA1045
KLF12 Kruppel-like factor 12
KLHL18 kelch-like family member 18
LOXL2 lysyl oxidase-like 2
LOXL3 lysyl oxidase-like 3
LRRC2 leucine rich repeat containing 2
MAPKBP1 mitogen-activated protein kinase binding protein 1
MAST2 microtubule associated serine/threonine kinase 2
METTL7A methyltransferase like 7A
MYL4 myosin, light chain 4, alkali; atrial, embryonic
NPHP1 nephronophthisis 1 (juvenile)
NR3C1 nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor)
NRSN2 neurensin 2
PBXIP1 pre-B-cell leukemia homeobox interacting protein 1
PER1 period circadian clock 1
PHF7 PHD finger protein 7
PHLPP2 PH domain and leucine rich repeat protein phosphatase 2
PNPLA3 patatin-like phospholipase domain containing 3
PPARD peroxisome proliferator-activated receptor delta
PRKCA protein kinase C, alpha
PRMT8 protein arginine methyltransferase 8
PRSS12 protease, serine, 12 (neurotrypsin, motopsin)
PTGER3 prostaglandin E receptor 3 (subtype EP3)
PTGS1 prostaglandin-endoperoxide synthase 1 (prostaglandin G/H synthase and cyclooxygenase)
PTPRM protein tyrosine phosphatase, receptor type, M
PTX3 pentraxin 3, long
RAB3IL1 RAB3A interacting protein (rabin3)-like 1
RASGRP2 RAS guanyl releasing protein 2 (calcium and DAG-regulated)
RNASE2 ribonuclease, RNase A family, 2 (liver, eosinophil-derived neurotoxin)
RUNX1T1 runt-related transcription factor 1; translocated to, 1 (cyclin D-related)
S100A8 S100 calcium binding protein A8
SEMA6B sema domain, transmembrane domain (TM), and cytoplasmic domain, (semaphorin) 6B
SH3BP2 SH3-domain binding protein 2
SLC16A4 solute carrier family 16, member 4
SLC22A18AS solute carrier family 22 (organic cation transporter), member 18 antisense
SLC34A2 solute carrier family 34 (type II sodium/phosphate cotransporter), member 2
SLCO4C1 solute carrier organic anion transporter family, member 4C1
SNTA1 syntrophin, alpha 1
STAB1 stabilin 1
TCF4 transcription factor 4
TEX13A testis expressed 13A
TNFRSF25 tumor necrosis factor receptor superfamily, member 25
TNFSF10 tumor necrosis factor (ligand) superfamily, member 10
TRBC1 T cell receptor beta constant 1
TRIM3 tripartite motif containing 3
TXNRD3 thioredoxin reductase 3
TYMP thymidine phosphorylase
UPB1 ureidopropionase, beta
WNT1 wingless-type MMTV integration site family, member 1
ZC4H2 zinc finger, C4H2 domain containing

decreased expression

Symbol Name
ACTL8 actin-like 8
ADGRG2 adhesion G protein-coupled receptor G2
ALAS1 5'-aminolevulinate synthase 1
ALDOC aldolase C, fructose-bisphosphate
APBB3 amyloid beta (A4) precursor protein-binding, family B, member 3
ATAD5 ATPase family, AAA domain containing 5
ATP13A2 ATPase type 13A2
B4GALT2 UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 2
BAG4 BCL2-associated athanogene 4
BBS7 Bardet-Biedl syndrome 7
BCL9 B-cell CLL/lymphoma 9
C11ORF95 chromosome 11 open reading frame 95
C5ORF45 chromosome 5 open reading frame 45
C7ORF43 chromosome 7 open reading frame 43
CBX7 chromobox homolog 7
CCDC132 coiled-coil domain containing 132
CCDC186 coiled-coil domain containing 186
CCP110 centriolar coiled coil protein 110kDa
CCT6B chaperonin containing TCP1, subunit 6B (zeta 2)
CGA glycoprotein hormones, alpha polypeptide
CHML choroideremia-like (Rab escort protein 2)
CIDEB cell death-inducing DFFA-like effector b
CLDN1 claudin 1
CLSPN claspin
CNKSR1 connector enhancer of kinase suppressor of Ras 1
CNPY3 canopy FGF signaling regulator 3
CTDP1 CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) phosphatase, subunit 1
CXORF21 chromosome X open reading frame 21
CYP26A1 cytochrome P450, family 26, subfamily A, polypeptide 1
DDIT3 DNA-damage-inducible transcript 3
DEAF1 DEAF1 transcription factor
DGAT1 diacylglycerol O-acyltransferase 1
DGKE diacylglycerol kinase, epsilon 64kDa
DIP2A DIP2 disco-interacting protein 2 homolog A (Drosophila)
ELOVL4 ELOVL fatty acid elongase 4
EPB41L5 erythrocyte membrane protein band 4.1 like 5
EPPK1 epiplakin 1
FAM169A family with sequence similarity 169, member A
GLCE glucuronic acid epimerase
GSTA4 glutathione S-transferase alpha 4
GTPBP2 GTP binding protein 2
HIST1H4D histone cluster 1, H4d
HMHA1 histocompatibility (minor) HA-1
IFT54 intraflagellar transport 54
IKZF5 IKAROS family zinc finger 5 (Pegasus)
ITGA3 integrin, alpha 3 (antigen CD49C, alpha 3 subunit of VLA-3 receptor)
LAIR2 leukocyte-associated immunoglobulin-like receptor 2
LAMA3 laminin, alpha 3
LOC202181 SUMO-interacting motifs containing 1 pseudogene
LRCH1 leucine-rich repeats and calponin homology (CH) domain containing 1
LRRC20 leucine rich repeat containing 20
LZTR1 leucine-zipper-like transcription regulator 1
MICAL1 microtubule associated monooxygenase, calponin and LIM domain containing 1
MUL1 mitochondrial E3 ubiquitin protein ligase 1
NDE1 nudE neurodevelopment protein 1
NDRG4 NDRG family member 4
NFE2L3 nuclear factor, erythroid 2-like 3
NPIPB3 nuclear pore complex interacting protein family, member B3
NXPE3 neurexophilin and PC-esterase domain family, member 3
OCA2 oculocutaneous albinism II
OSMR oncostatin M receptor
PDSS2 prenyl (decaprenyl) diphosphate synthase, subunit 2
PIM1 Pim-1 proto-oncogene, serine/threonine kinase
PLCXD1 phosphatidylinositol-specific phospholipase C, X domain containing 1
POLL polymerase (DNA directed), lambda
POM121 POM121 transmembrane nucleoporin
PTCD2 pentatricopeptide repeat domain 2
RAB3D RAB3D, member RAS oncogene family
RAD51B RAD51 paralog B
RNPEPL1 arginyl aminopeptidase (aminopeptidase B)-like 1
RPGR retinitis pigmentosa GTPase regulator
SCAI suppressor of cancer cell invasion
SECISBP2 SECIS binding protein 2
SLC22A4 solute carrier family 22 (organic cation/zwitterion transporter), member 4
SLC44A1 solute carrier family 44 (choline transporter), member 1
SLC8B1 solute carrier family 8 (sodium/lithium/calcium exchanger), member B1
SP1 Sp1 transcription factor
SPINK5 serine peptidase inhibitor, Kazal type 5
SPRYD7 SPRY domain containing 7
SRPX sushi-repeat containing protein, X-linked
STARD5 StAR-related lipid transfer (START) domain containing 5
TEP1 telomerase-associated protein 1
TMEM2 transmembrane protein 2
TNFRSF11A tumor necrosis factor receptor superfamily, member 11a, NFKB activator
TREM1 triggering receptor expressed on myeloid cells 1
TUBG2 tubulin, gamma 2
USP36 ubiquitin specific peptidase 36
UTP20 UTP20, small subunit (SSU) processome component, homolog (yeast)
WDR60 WD repeat domain 60
XRCC3 X-ray repair complementing defective repair in Chinese hamster cells 3
ZBTB39 zinc finger and BTB domain containing 39
ZCWPW1 zinc finger, CW type with PWWP domain 1
ZNF141 zinc finger protein 141
ZNF286A zinc finger protein 286A
ZNF573 zinc finger protein 573
ZNF747 zinc finger protein 747