ritonavir Gene Set

Dataset	GeneRIF Biological Term Annotations
Category	structural or functional annotations
Type	biological term
Description	A L-valine derivative in which the alpha-nitrogen of L-valinamide is substituted with a methyl{[2-(propan-2-yl)-1,3-thiazol-4-yl]methyl}carbamoyl group and the amide nitrogen by a (2S,4S,5S)-4-hydroxy-1,6-diphenyl-5-{[(1,3-thiazol-5-ylmethoxy)carbonyl]amino}hexan-2-yl group. An antiretroviral drug from the protease inhibitor class used to treat HIV infection and AIDS, it is often used as a fixed-dose combination with another protease inhibitor, lopinavir. (Chemical Entities of Biological Interest Ontology, CHEBI_45409)
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Genes

9 genes co-occuring with the biological term ritonavir in literature-supported statements describing functions of genes from the GeneRIF Biological Term Annotations dataset.

Symbol	Name
ABCB1	ATP-binding cassette, sub-family B (MDR/TAP), member 1
ACSS2	acyl-CoA synthetase short-chain family member 2
CYP3A	cytochrome P450, family 3, subfamily A
CYP3A4	cytochrome P450, family 3, subfamily A, polypeptide 4
CYP3A5	cytochrome P450, family 3, subfamily A, polypeptide 5
DUSP1	dual specificity phosphatase 1
KBTBD3	kelch repeat and BTB (POZ) domain containing 3
NCEH1	neutral cholesterol ester hydrolase 1
NOS3	nitric oxide synthase 3 (endothelial cell)