| Dataset | CMAP Signatures of Differentially Expressed Genes for Small Molecules |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis) |
| Similar Terms | |
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197 genes differentially expressed following the rofecoxib-166 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
| Symbol | Name |
|---|---|
| AKR7A3 | aldo-keto reductase family 7, member A3 (aflatoxin aldehyde reductase) |
| APBB2 | amyloid beta (A4) precursor protein-binding, family B, member 2 |
| AQP2 | aquaporin 2 (collecting duct) |
| ARMC4 | armadillo repeat containing 4 |
| ATXN2L | ataxin 2-like |
| AXIN1 | axin 1 |
| B3GAT3 | beta-1,3-glucuronyltransferase 3 |
| BAZ2A | bromodomain adjacent to zinc finger domain, 2A |
| BICD1 | bicaudal D homolog 1 (Drosophila) |
| BMP7 | bone morphogenetic protein 7 |
| CAMK2G | calcium/calmodulin-dependent protein kinase II gamma |
| CCBL2 | cysteine conjugate-beta lyase 2 |
| CCRN4L | CCR4 carbon catabolite repression 4-like (S. cerevisiae) |
| CCS | copper chaperone for superoxide dismutase |
| CHMP5 | charged multivesicular body protein 5 |
| CHRNA2 | cholinergic receptor, nicotinic, alpha 2 (neuronal) |
| CLIC4 | chloride intracellular channel 4 |
| CLIP1 | CAP-GLY domain containing linker protein 1 |
| CNNM2 | cyclin and CBS domain divalent metal cation transport mediator 2 |
| CNTD2 | cyclin N-terminal domain containing 2 |
| COQ3 | coenzyme Q3 methyltransferase |
| COX5B | cytochrome c oxidase subunit Vb |
| CREBL2 | cAMP responsive element binding protein-like 2 |
| CUL4B | cullin 4B |
| CYP2A6 | cytochrome P450, family 2, subfamily A, polypeptide 6 |
| DMWD | dystrophia myotonica, WD repeat containing |
| DNAJC4 | DnaJ (Hsp40) homolog, subfamily C, member 4 |
| ECHDC1 | ethylmalonyl-CoA decarboxylase 1 |
| EGR4 | early growth response 4 |
| ERN2 | endoplasmic reticulum to nucleus signaling 2 |
| FGFR1 | fibroblast growth factor receptor 1 |
| FMOD | fibromodulin |
| GGA1 | golgi-associated, gamma adaptin ear containing, ARF binding protein 1 |
| GLI3 | GLI family zinc finger 3 |
| GLRX3 | glutaredoxin 3 |
| GLUL | glutamate-ammonia ligase |
| GNAQ | guanine nucleotide binding protein (G protein), q polypeptide |
| GRK5 | G protein-coupled receptor kinase 5 |
| GRK6 | G protein-coupled receptor kinase 6 |
| GTPBP2 | GTP binding protein 2 |
| GTSE1 | G-2 and S-phase expressed 1 |
| HFE | hemochromatosis |
| HIGD1A | HIG1 hypoxia inducible domain family, member 1A |
| HLA-DRB6 | major histocompatibility complex, class II, DR beta 6 (pseudogene) |
| HLA-G | major histocompatibility complex, class I, G |
| IDUA | iduronidase, alpha-L- |
| IKZF1 | IKAROS family zinc finger 1 (Ikaros) |
| KCNAB2 | potassium channel, voltage gated subfamily A regulatory beta subunit 2 |
| LMNA | lamin A/C |
| MEFV | Mediterranean fever |
| MINK1 | misshapen-like kinase 1 |
| MT1H | metallothionein 1H |
| MYL4 | myosin, light chain 4, alkali; atrial, embryonic |
| MYO19 | myosin XIX |
| NEURL1 | neuralized E3 ubiquitin protein ligase 1 |
| NOL6 | nucleolar protein 6 (RNA-associated) |
| NUMA1 | nuclear mitotic apparatus protein 1 |
| OAS3 | 2'-5'-oligoadenylate synthetase 3, 100kDa |
| OPHN1 | oligophrenin 1 |
| OSBPL2 | oxysterol binding protein-like 2 |
| PAFAH1B2 | platelet-activating factor acetylhydrolase 1b, catalytic subunit 2 (30kDa) |
| PDXK | pyridoxal (pyridoxine, vitamin B6) kinase |
| PLD2 | phospholipase D2 |
| PLEKHG3 | pleckstrin homology domain containing, family G (with RhoGef domain) member 3 |
| PODXL | podocalyxin-like |
| PPT2 | palmitoyl-protein thioesterase 2 |
| PTCRA | pre T-cell antigen receptor alpha |
| RAB29 | RAB29, member RAS oncogene family |
| RAB4B | RAB4B, member RAS oncogene family |
| RECK | reversion-inducing-cysteine-rich protein with kazal motifs |
| RNF208 | ring finger protein 208 |
| SCAMP1 | secretory carrier membrane protein 1 |
| SCD5 | stearoyl-CoA desaturase 5 |
| SEMA7A | semaphorin 7A, GPI membrane anchor (John Milton Hagen blood group) |
| SIGLEC6 | sialic acid binding Ig-like lectin 6 |
| SLC17A5 | solute carrier family 17 (acidic sugar transporter), member 5 |
| SPN | sialophorin |
| SPRR1A | small proline-rich protein 1A |
| SYF2 | SYF2 pre-mRNA-splicing factor |
| TAF1C | TATA box binding protein (TBP)-associated factor, RNA polymerase I, C, 110kDa |
| TAF6L | TAF6-like RNA polymerase II, p300/CBP-associated factor (PCAF)-associated factor, 65kDa |
| TFG | TRK-fused gene |
| TGS1 | trimethylguanosine synthase 1 |
| TIMP3 | TIMP metallopeptidase inhibitor 3 |
| TLN1 | talin 1 |
| TMPRSS6 | transmembrane protease, serine 6 |
| TSPAN1 | tetraspanin 1 |
| TSPAN9 | tetraspanin 9 |
| TUBA4B | tubulin, alpha 4b |
| VPS13D | vacuolar protein sorting 13 homolog D (S. cerevisiae) |
| ZBTB40 | zinc finger and BTB domain containing 40 |
| ZC3H3 | zinc finger CCCH-type containing 3 |
| ZFHX2 | zinc finger homeobox 2 |
| ZNF117 | zinc finger protein 117 |
| ZNF576 | zinc finger protein 576 |
| ZNF586 | zinc finger protein 586 |
| ZNF747 | zinc finger protein 747 |
| Symbol | Name |
|---|---|
| ADCK3 | aarF domain containing kinase 3 |
| ADIRF | adipogenesis regulatory factor |
| AMMECR1 | Alport syndrome, mental retardation, midface hypoplasia and elliptocytosis chromosomal region gene 1 |
| ANKRD40 | ankyrin repeat domain 40 |
| ANXA6 | annexin A6 |
| APP | amyloid beta (A4) precursor protein |
| ATAD3A | ATPase family, AAA domain containing 3A |
| BBC3 | BCL2 binding component 3 |
| BCCIP | BRCA2 and CDKN1A interacting protein |
| BCL9 | B-cell CLL/lymphoma 9 |
| C11ORF68 | chromosome 11 open reading frame 68 |
| C12ORF43 | chromosome 12 open reading frame 43 |
| C2CD5 | C2 calcium-dependent domain containing 5 |
| C5ORF22 | chromosome 5 open reading frame 22 |
| C9ORF78 | chromosome 9 open reading frame 78 |
| CCDC59 | coiled-coil domain containing 59 |
| CD53 | CD53 molecule |
| CD82 | CD82 molecule |
| CDC23 | cell division cycle 23 |
| CDT1 | chromatin licensing and DNA replication factor 1 |
| COBL | cordon-bleu WH2 repeat protein |
| COMMD8 | COMM domain containing 8 |
| CRBN | cereblon |
| CROT | carnitine O-octanoyltransferase |
| CRYZ | crystallin, zeta (quinone reductase) |
| DAXX | death-domain associated protein |
| DDA1 | DET1 and DDB1 associated 1 |
| DGKD | diacylglycerol kinase, delta 130kDa |
| DONSON | downstream neighbor of SON |
| DPH2 | DPH2 homolog (S. cerevisiae) |
| DSG2 | desmoglein 2 |
| DTX4 | deltex 4, E3 ubiquitin ligase |
| EVPL | envoplakin |
| EXOSC9 | exosome component 9 |
| FAH | fumarylacetoacetate hydrolase (fumarylacetoacetase) |
| FKBPL | FK506 binding protein like |
| FUZ | fuzzy planar cell polarity protein |
| FZD2 | frizzled class receptor 2 |
| GNA12 | guanine nucleotide binding protein (G protein) alpha 12 |
| GNPDA1 | glucosamine-6-phosphate deaminase 1 |
| HECTD3 | HECT domain containing E3 ubiquitin protein ligase 3 |
| HTRA1 | HtrA serine peptidase 1 |
| IL17RA | interleukin 17 receptor A |
| ING3 | inhibitor of growth family, member 3 |
| IPP | intracisternal A particle-promoted polypeptide |
| ITGA5 | integrin, alpha 5 (fibronectin receptor, alpha polypeptide) |
| KIF3B | kinesin family member 3B |
| LGMN | legumain |
| LMNB1 | lamin B1 |
| LSM14B | LSM14B, SCD6 homolog B (S. cerevisiae) |
| LTBR | lymphotoxin beta receptor (TNFR superfamily, member 3) |
| LYPD3 | LY6/PLAUR domain containing 3 |
| MAP3K2 | mitogen-activated protein kinase kinase kinase 2 |
| MAPK3 | mitogen-activated protein kinase 3 |
| MMP17 | matrix metallopeptidase 17 (membrane-inserted) |
| MUL1 | mitochondrial E3 ubiquitin protein ligase 1 |
| NARF | nuclear prelamin A recognition factor |
| NCS1 | neuronal calcium sensor 1 |
| NEMF | nuclear export mediator factor |
| NSD1 | nuclear receptor binding SET domain protein 1 |
| PDLIM2 | PDZ and LIM domain 2 (mystique) |
| PDSS2 | prenyl (decaprenyl) diphosphate synthase, subunit 2 |
| PFKFB3 | 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 3 |
| PGM3 | phosphoglucomutase 3 |
| PHF11 | PHD finger protein 11 |
| PHLDA2 | pleckstrin homology-like domain, family A, member 2 |
| PIGB | phosphatidylinositol glycan anchor biosynthesis, class B |
| PIM2 | Pim-2 proto-oncogene, serine/threonine kinase |
| PLEK2 | pleckstrin 2 |
| PMP22 | peripheral myelin protein 22 |
| POLR1B | polymerase (RNA) I polypeptide B, 128kDa |
| R3HDM2 | R3H domain containing 2 |
| RAB20 | RAB20, member RAS oncogene family |
| RACGAP1 | Rac GTPase activating protein 1 |
| RBM14 | RNA binding motif protein 14 |
| RNF121 | ring finger protein 121 |
| RPAP1 | RNA polymerase II associated protein 1 |
| RPS6KA1 | ribosomal protein S6 kinase, 90kDa, polypeptide 1 |
| S100A7 | S100 calcium binding protein A7 |
| SLC43A1 | solute carrier family 43 (amino acid system L transporter), member 1 |
| SLC9A1 | solute carrier family 9, subfamily A (NHE1, cation proton antiporter 1), member 1 |
| SMU1 | smu-1 suppressor of mec-8 and unc-52 homolog (C. elegans) |
| SMYD5 | SMYD family member 5 |
| SPIN1 | spindlin 1 |
| SSSCA1 | Sjogren syndrome/scleroderma autoantigen 1 |
| STT3A | STT3A, subunit of the oligosaccharyltransferase complex (catalytic) |
| TAOK1 | TAO kinase 1 |
| TBC1D15 | TBC1 domain family, member 15 |
| TBCC | tubulin folding cofactor C |
| TOE1 | target of EGR1, member 1 (nuclear) |
| TSPYL4 | TSPY-like 4 |
| TTC4 | tetratricopeptide repeat domain 4 |
| UBXN8 | UBX domain protein 8 |
| UNC119B | unc-119 homolog B (C. elegans) |
| UPK3B | uroplakin 3B |
| WDR13 | WD repeat domain 13 |
| XRCC2 | X-ray repair complementing defective repair in Chinese hamster cells 2 |
| ZHX2 | zinc fingers and homeoboxes 2 |
| ZMAT3 | zinc finger, matrin-type 3 |
| ZNF443 | zinc finger protein 443 |
