| Dataset | CMAP Signatures of Differentially Expressed Genes for Small Molecules |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis) |
| Similar Terms | |
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195 genes differentially expressed following the rofecoxib-205 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
| Symbol | Name |
|---|---|
| ACADS | acyl-CoA dehydrogenase, C-2 to C-3 short chain |
| ADAM22 | ADAM metallopeptidase domain 22 |
| ADARB1 | adenosine deaminase, RNA-specific, B1 |
| ADCY1 | adenylate cyclase 1 (brain) |
| AGFG2 | ArfGAP with FG repeats 2 |
| AHCYL1 | adenosylhomocysteinase-like 1 |
| ALKBH4 | alkB, alkylation repair homolog 4 (E. coli) |
| ALOX12P2 | arachidonate 12-lipoxygenase pseudogene 2 |
| AQP6 | aquaporin 6, kidney specific |
| ARHGAP24 | Rho GTPase activating protein 24 |
| ARMC4 | armadillo repeat containing 4 |
| B3GAT3 | beta-1,3-glucuronyltransferase 3 |
| BCL2 | B-cell CLL/lymphoma 2 |
| BLK | BLK proto-oncogene, Src family tyrosine kinase |
| BRAF | B-Raf proto-oncogene, serine/threonine kinase |
| CACNA1I | calcium channel, voltage-dependent, T type, alpha 1I subunit |
| CAMKV | CaM kinase-like vesicle-associated |
| CCDC176 | coiled-coil domain containing 176 |
| CCNT2 | cyclin T2 |
| CEACAM6 | carcinoembryonic antigen-related cell adhesion molecule 6 (non-specific cross reacting antigen) |
| CEBPE | CCAAT/enhancer binding protein (C/EBP), epsilon |
| CILP | cartilage intermediate layer protein, nucleotide pyrophosphohydrolase |
| COX5B | cytochrome c oxidase subunit Vb |
| CPB1 | carboxypeptidase B1 (tissue) |
| CRMP1 | collapsin response mediator protein 1 |
| CTSO | cathepsin O |
| CUL4B | cullin 4B |
| CYB561 | cytochrome b561 |
| DGCR8 | DGCR8 microprocessor complex subunit |
| DNAAF2 | dynein, axonemal, assembly factor 2 |
| DUSP9 | dual specificity phosphatase 9 |
| ELMO2 | engulfment and cell motility 2 |
| ENOX2 | ecto-NOX disulfide-thiol exchanger 2 |
| EPS8L3 | EPS8-like 3 |
| GEMIN7 | gem (nuclear organelle) associated protein 7 |
| GHRHR | growth hormone releasing hormone receptor |
| GLB1L | galactosidase, beta 1-like |
| GON4L | gon-4-like (C. elegans) |
| GPLD1 | glycosylphosphatidylinositol specific phospholipase D1 |
| GPR176 | G protein-coupled receptor 176 |
| GRIN1 | glutamate receptor, ionotropic, N-methyl D-aspartate 1 |
| GSK3A | glycogen synthase kinase 3 alpha |
| GYPC | glycophorin C (Gerbich blood group) |
| HGF | hepatocyte growth factor (hepapoietin A; scatter factor) |
| HHIPL2 | HHIP-like 2 |
| HOMER3 | homer scaffolding protein 3 |
| HOXD1 | homeobox D1 |
| IL1RN | interleukin 1 receptor antagonist |
| ING4 | inhibitor of growth family, member 4 |
| KIAA0141 | KIAA0141 |
| KIR2DL5A | killer cell immunoglobulin-like receptor, two domains, long cytoplasmic tail, 5A |
| KMT2A | lysine (K)-specific methyltransferase 2A |
| LY6G6D | lymphocyte antigen 6 complex, locus G6D |
| LZTS1 | leucine zipper, putative tumor suppressor 1 |
| MADCAM1 | mucosal vascular addressin cell adhesion molecule 1 |
| MARC2 | mitochondrial amidoxime reducing component 2 |
| MBNL2 | muscleblind-like splicing regulator 2 |
| MIPEP | mitochondrial intermediate peptidase |
| MST1 | macrophage stimulating 1 |
| NFATC1 | nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 1 |
| NHEJ1 | nonhomologous end-joining factor 1 |
| NMT1 | N-myristoyltransferase 1 |
| NTRK3 | neurotrophic tyrosine kinase, receptor, type 3 |
| NUP98 | nucleoporin 98kDa |
| ORC1 | origin recognition complex, subunit 1 |
| PARG | poly (ADP-ribose) glycohydrolase |
| PAX8 | paired box 8 |
| PDCD4 | programmed cell death 4 (neoplastic transformation inhibitor) |
| PLA2G2A | phospholipase A2, group IIA (platelets, synovial fluid) |
| PTCRA | pre T-cell antigen receptor alpha |
| RALB | v-ral simian leukemia viral oncogene homolog B |
| RIC3 | RIC3 acetylcholine receptor chaperone |
| RNASE1 | ribonuclease, RNase A family, 1 (pancreatic) |
| S100A1 | S100 calcium binding protein A1 |
| SASH1 | SAM and SH3 domain containing 1 |
| SEMA6A | sema domain, transmembrane domain (TM), and cytoplasmic domain, (semaphorin) 6A |
| SFTPC | surfactant protein C |
| SGSM3 | small G protein signaling modulator 3 |
| SHPK | sedoheptulokinase |
| SLC10A1 | solute carrier family 10 (sodium/bile acid cotransporter), member 1 |
| SLC2A5 | solute carrier family 2 (facilitated glucose/fructose transporter), member 5 |
| SMYD5 | SMYD family member 5 |
| SPG20 | spastic paraplegia 20 (Troyer syndrome) |
| SYT12 | synaptotagmin XII |
| TBC1D4 | TBC1 domain family, member 4 |
| TCF7 | transcription factor 7 (T-cell specific, HMG-box) |
| TNPO2 | transportin 2 |
| TRAM2 | translocation associated membrane protein 2 |
| TSC22D2 | TSC22 domain family, member 2 |
| VPS39 | vacuolar protein sorting 39 homolog (S. cerevisiae) |
| WDR5B | WD repeat domain 5B |
| WIPF1 | WAS/WASL interacting protein family, member 1 |
| ZAK | sterile alpha motif and leucine zipper containing kinase AZK |
| ZMYM2 | zinc finger, MYM-type 2 |
| ZNF576 | zinc finger protein 576 |
| ZNF609 | zinc finger protein 609 |
| Symbol | Name |
|---|---|
| ADAM9 | ADAM metallopeptidase domain 9 |
| ATF7IP2 | activating transcription factor 7 interacting protein 2 |
| AXIN1 | axin 1 |
| BBC3 | BCL2 binding component 3 |
| BCL2L14 | BCL2-like 14 (apoptosis facilitator) |
| BRS3 | bombesin-like receptor 3 |
| C11ORF80 | chromosome 11 open reading frame 80 |
| C14ORF79 | chromosome 14 open reading frame 79 |
| C19ORF73 | chromosome 19 open reading frame 73 |
| CASP3 | caspase 3, apoptosis-related cysteine peptidase |
| CCDC25 | coiled-coil domain containing 25 |
| CCDC28A | coiled-coil domain containing 28A |
| CCDC94 | coiled-coil domain containing 94 |
| CCNJL | cyclin J-like |
| CD82 | CD82 molecule |
| CDT1 | chromatin licensing and DNA replication factor 1 |
| CES3 | carboxylesterase 3 |
| CLPB | ClpB homolog, mitochondrial AAA ATPase chaperonin |
| CMAS | cytidine monophosphate N-acetylneuraminic acid synthetase |
| CNTD2 | cyclin N-terminal domain containing 2 |
| CNTN1 | contactin 1 |
| COBL | cordon-bleu WH2 repeat protein |
| CORO7 | coronin 7 |
| CTNNBIP1 | catenin, beta interacting protein 1 |
| CYP26A1 | cytochrome P450, family 26, subfamily A, polypeptide 1 |
| DGCR5 | DiGeorge syndrome critical region gene 5 (non-protein coding) |
| DNAJC3 | DnaJ (Hsp40) homolog, subfamily C, member 3 |
| DYRK3 | dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 3 |
| EIF2AK2 | eukaryotic translation initiation factor 2-alpha kinase 2 |
| EPX | eosinophil peroxidase |
| ERCC2 | excision repair cross-complementation group 2 |
| FBXL15 | F-box and leucine-rich repeat protein 15 |
| FGF16 | fibroblast growth factor 16 |
| FGGY | FGGY carbohydrate kinase domain containing |
| FKBP6 | FK506 binding protein 6, 36kDa |
| FRMD1 | FERM domain containing 1 |
| FUZ | fuzzy planar cell polarity protein |
| GCKR | glucokinase (hexokinase 4) regulator |
| GLS2 | glutaminase 2 (liver, mitochondrial) |
| GP6 | glycoprotein VI (platelet) |
| GRIP2 | glutamate receptor interacting protein 2 |
| GRK1 | G protein-coupled receptor kinase 1 |
| HBD | hemoglobin, delta |
| HDAC7 | histone deacetylase 7 |
| HHLA1 | HERV-H LTR-associating 1 |
| IFIT2 | interferon-induced protein with tetratricopeptide repeats 2 |
| IL15RA | interleukin 15 receptor, alpha |
| KCNN1 | potassium channel, calcium activated intermediate/small conductance subfamily N alpha, member 1 |
| KLHL26 | kelch-like family member 26 |
| LHB | luteinizing hormone beta polypeptide |
| LMTK1 | lemur tail kinase 1 |
| LOC100286895 | cell division cycle 27 homolog pseudogene |
| MARC1 | mitochondrial amidoxime reducing component 1 |
| MON1B | MON1 secretory trafficking family member B |
| MTERF4 | mitochondrial transcription termination factor 4 |
| NKAIN1 | Na+/K+ transporting ATPase interacting 1 |
| NKX2-5 | NK2 homeobox 5 |
| NMNAT2 | nicotinamide nucleotide adenylyltransferase 2 |
| NUPL2 | nucleoporin like 2 |
| PAN2 | PAN2 poly(A) specific ribonuclease subunit |
| PCSK7 | proprotein convertase subtilisin/kexin type 7 |
| PDZD7 | PDZ domain containing 7 |
| PIPOX | pipecolic acid oxidase |
| PLCD1 | phospholipase C, delta 1 |
| PLEKHO1 | pleckstrin homology domain containing, family O member 1 |
| PLXNB3 | plexin B3 |
| PROZ | protein Z, vitamin K-dependent plasma glycoprotein |
| PRRG3 | proline rich Gla (G-carboxyglutamic acid) 3 (transmembrane) |
| RAB3A | RAB3A, member RAS oncogene family |
| REM1 | RAS (RAD and GEM)-like GTP-binding 1 |
| RND1 | Rho family GTPase 1 |
| RNF141 | ring finger protein 141 |
| RNF39 | ring finger protein 39 |
| S1PR4 | sphingosine-1-phosphate receptor 4 |
| SLC17A4 | solute carrier family 17, member 4 |
| SLC20A2 | solute carrier family 20 (phosphate transporter), member 2 |
| SLC25A28 | solute carrier family 25 (mitochondrial iron transporter), member 28 |
| SLC6A3 | solute carrier family 6 (neurotransmitter transporter), member 3 |
| SLC9A8 | solute carrier family 9, subfamily A (NHE8, cation proton antiporter 8), member 8 |
| SLCO2A1 | solute carrier organic anion transporter family, member 2A1 |
| SMPD2 | sphingomyelin phosphodiesterase 2, neutral membrane (neutral sphingomyelinase) |
| SNAPC2 | small nuclear RNA activating complex, polypeptide 2, 45kDa |
| SOX21 | SRY (sex determining region Y)-box 21 |
| STAB2 | stabilin 2 |
| SULT4A1 | sulfotransferase family 4A, member 1 |
| SUZ12P1 | suppressor of zeste 12 homolog pseudogene 1 |
| SYNPO | synaptopodin |
| TET3 | tet methylcytosine dioxygenase 3 |
| TGM5 | transglutaminase 5 |
| TMEM242 | transmembrane protein 242 |
| TMPRSS5 | transmembrane protease, serine 5 |
| TRAC | T cell receptor alpha constant |
| USB1 | U6 snRNA biogenesis 1 |
| WDR13 | WD repeat domain 13 |
| WNT10B | wingless-type MMTV integration site family, member 10B |
| ZNF248 | zinc finger protein 248 |
| ZNF652 | zinc finger protein 652 |
| ZNHIT2 | zinc finger, HIT-type containing 2 |
| ZXDC | ZXD family zinc finger C |
