| Dataset | CMAP Signatures of Differentially Expressed Genes for Small Molecules |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis) |
| Similar Terms | |
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196 genes differentially expressed following the rofecoxib-251 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
| Symbol | Name |
|---|---|
| ABHD2 | abhydrolase domain containing 2 |
| ACADS | acyl-CoA dehydrogenase, C-2 to C-3 short chain |
| ALPK1 | alpha-kinase 1 |
| ASIC4 | acid sensing (proton gated) ion channel family member 4 |
| ATG13 | autophagy related 13 |
| ATXN8OS | ATXN8 opposite strand (non-protein coding) |
| BIN1 | bridging integrator 1 |
| BRF2 | BRF2, RNA polymerase III transcription initiation factor 50 kDa subunit |
| CARTPT | CART prepropeptide |
| CASP10 | caspase 10, apoptosis-related cysteine peptidase |
| CASR | calcium-sensing receptor |
| CCDC87 | coiled-coil domain containing 87 |
| CCKAR | cholecystokinin A receptor |
| CD6 | CD6 molecule |
| CDK10 | cyclin-dependent kinase 10 |
| CEP170 | centrosomal protein 170kDa |
| CHRM5 | cholinergic receptor, muscarinic 5 |
| COX4I1 | cytochrome c oxidase subunit IV isoform 1 |
| CPT1A | carnitine palmitoyltransferase 1A (liver) |
| CXCR6 | chemokine (C-X-C motif) receptor 6 |
| DUSP2 | dual specificity phosphatase 2 |
| ENO2 | enolase 2 (gamma, neuronal) |
| EPOR | erythropoietin receptor |
| ESR2 | estrogen receptor 2 (ER beta) |
| FAM107A | family with sequence similarity 107, member A |
| FAM65A | family with sequence similarity 65, member A |
| FEZ1 | fasciculation and elongation protein zeta 1 (zygin I) |
| FKBP8 | FK506 binding protein 8, 38kDa |
| FN3K | fructosamine 3 kinase |
| FOSL1 | FOS-like antigen 1 |
| FOXRED2 | FAD-dependent oxidoreductase domain containing 2 |
| FRMPD1 | FERM and PDZ domain containing 1 |
| GAL3ST4 | galactose-3-O-sulfotransferase 4 |
| GAS2L1 | growth arrest-specific 2 like 1 |
| GIMAP5 | GTPase, IMAP family member 5 |
| GIT2 | G protein-coupled receptor kinase interacting ArfGAP 2 |
| GLRA2 | glycine receptor, alpha 2 |
| GLS2 | glutaminase 2 (liver, mitochondrial) |
| GNB1L | guanine nucleotide binding protein (G protein), beta polypeptide 1-like |
| GPR3 | G protein-coupled receptor 3 |
| GUCY1A2 | guanylate cyclase 1, soluble, alpha 2 |
| GYPB | glycophorin B (MNS blood group) |
| HMHA1 | histocompatibility (minor) HA-1 |
| HOXC5 | homeobox C5 |
| HPS1 | Hermansky-Pudlak syndrome 1 |
| HRASLS2 | HRAS-like suppressor 2 |
| HSPA6 | heat shock 70kDa protein 6 (HSP70B') |
| ICAM1 | intercellular adhesion molecule 1 |
| IGHG1 | immunoglobulin heavy constant gamma 1 (G1m marker) |
| ING1 | inhibitor of growth family, member 1 |
| INPP4A | inositol polyphosphate-4-phosphatase, type I, 107kDa |
| KAZN | kazrin, periplakin interacting protein |
| KDM8 | lysine (K)-specific demethylase 8 |
| KIFC3 | kinesin family member C3 |
| L1CAM | L1 cell adhesion molecule |
| LMTK2 | lemur tyrosine kinase 2 |
| LTBP4 | latent transforming growth factor beta binding protein 4 |
| LTK | leukocyte receptor tyrosine kinase |
| MAGEA5 | melanoma antigen family A5 |
| MAPK8 | mitogen-activated protein kinase 8 |
| MDC1 | mediator of DNA-damage checkpoint 1 |
| MGC2889 | uncharacterized protein MGC2889 |
| MLXIPL | MLX interacting protein-like |
| NAB2 | NGFI-A binding protein 2 (EGR1 binding protein 2) |
| NR4A1 | nuclear receptor subfamily 4, group A, member 1 |
| NUDT4 | nudix (nucleoside diphosphate linked moiety X)-type motif 4 |
| NXF2 | nuclear RNA export factor 2 |
| ORC4 | origin recognition complex, subunit 4 |
| P2RY11 | purinergic receptor P2Y, G-protein coupled, 11 |
| PAX1 | paired box 1 |
| PDXK | pyridoxal (pyridoxine, vitamin B6) kinase |
| PLXNB3 | plexin B3 |
| PPIL2 | peptidylprolyl isomerase (cyclophilin)-like 2 |
| PPP1R10 | protein phosphatase 1, regulatory subunit 10 |
| PYCRL | pyrroline-5-carboxylate reductase-like |
| PYGM | phosphorylase, glycogen, muscle |
| RASA3 | RAS p21 protein activator 3 |
| RMND5A | required for meiotic nuclear division 5 homolog A (S. cerevisiae) |
| RNF41 | ring finger protein 41, E3 ubiquitin protein ligase |
| RNFT2 | ring finger protein, transmembrane 2 |
| RPL10L | ribosomal protein L10-like |
| SERPINE1 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 |
| SLC22A17 | solute carrier family 22, member 17 |
| SLC30A5 | solute carrier family 30 (zinc transporter), member 5 |
| TESC | tescalcin |
| TICAM1 | toll-like receptor adaptor molecule 1 |
| TMEM140 | transmembrane protein 140 |
| TRAPPC12 | trafficking protein particle complex 12 |
| TRMT2A | tRNA methyltransferase 2 homolog A (S. cerevisiae) |
| TSPAN32 | tetraspanin 32 |
| TXNL4A | thioredoxin-like 4A |
| UTY | ubiquitously transcribed tetratricopeptide repeat containing, Y-linked |
| WIPF1 | WAS/WASL interacting protein family, member 1 |
| WT1-AS | WT1 antisense RNA |
| ZBTB7A | zinc finger and BTB domain containing 7A |
| ZFP64 | ZFP64 zinc finger protein |
| ZNF184 | zinc finger protein 184 |
| ZNF335 | zinc finger protein 335 |
| Symbol | Name |
|---|---|
| AFM | afamin |
| AGPS | alkylglycerone phosphate synthase |
| APOLD1 | apolipoprotein L domain containing 1 |
| ATP8B1 | ATPase, aminophospholipid transporter, class I, type 8B, member 1 |
| C1ORF109 | chromosome 1 open reading frame 109 |
| CAV3 | caveolin 3 |
| CCDC71 | coiled-coil domain containing 71 |
| CCR4 | chemokine (C-C motif) receptor 4 |
| CCS | copper chaperone for superoxide dismutase |
| CDKL3 | cyclin-dependent kinase-like 3 |
| CEP41 | centrosomal protein 41kDa |
| CHRNB2 | cholinergic receptor, nicotinic, beta 2 (neuronal) |
| CLPS | colipase, pancreatic |
| CNTN1 | contactin 1 |
| CYP26A1 | cytochrome P450, family 26, subfamily A, polypeptide 1 |
| CYP2B7P | cytochrome P450, family 2, subfamily B, polypeptide 7, pseudogene |
| DMBT1 | deleted in malignant brain tumors 1 |
| DPP6 | dipeptidyl-peptidase 6 |
| EGR2 | early growth response 2 |
| EXOSC9 | exosome component 9 |
| F3 | coagulation factor III (thromboplastin, tissue factor) |
| FAM110D | family with sequence similarity 110, member D |
| FBXO22 | F-box protein 22 |
| FGFBP1 | fibroblast growth factor binding protein 1 |
| FKBP10 | FK506 binding protein 10, 65 kDa |
| FOLR3 | folate receptor 3 (gamma) |
| FTCD | formimidoyltransferase cyclodeaminase |
| GFPT2 | glutamine-fructose-6-phosphate transaminase 2 |
| GMEB1 | glucocorticoid modulatory element binding protein 1 |
| GPR21 | G protein-coupled receptor 21 |
| HERC6 | HECT and RLD domain containing E3 ubiquitin protein ligase family member 6 |
| IFI27 | interferon, alpha-inducible protein 27 |
| IFIT2 | interferon-induced protein with tetratricopeptide repeats 2 |
| IFT22 | intraflagellar transport 22 |
| IRF8 | interferon regulatory factor 8 |
| KCNJ2 | potassium channel, inwardly rectifying subfamily J, member 2 |
| KDM5D | lysine (K)-specific demethylase 5D |
| KIR2DS1 | killer cell immunoglobulin-like receptor, two domains, short cytoplasmic tail, 1 |
| KRBOX4 | KRAB box domain containing 4 |
| LHX6 | LIM homeobox 6 |
| LOC100127972 | uncharacterized LOC100127972 |
| LPAR6 | lysophosphatidic acid receptor 6 |
| LRCH1 | leucine-rich repeats and calponin homology (CH) domain containing 1 |
| LRP2 | low density lipoprotein receptor-related protein 2 |
| MAGOHB | mago-nashi homolog B (Drosophila) |
| MAOB | monoamine oxidase B |
| MEIS2 | Meis homeobox 2 |
| MFGE8 | milk fat globule-EGF factor 8 protein |
| MTERF4 | mitochondrial transcription termination factor 4 |
| MYL1 | myosin, light chain 1, alkali; skeletal, fast |
| MYOC | myocilin, trabecular meshwork inducible glucocorticoid response |
| NAP1L2 | nucleosome assembly protein 1-like 2 |
| NEIL1 | nei endonuclease VIII-like 1 (E. coli) |
| NELL2 | NEL-like 2 (chicken) |
| NME5 | NME/NM23 family member 5 |
| NMNAT2 | nicotinamide nucleotide adenylyltransferase 2 |
| NOTCH4 | notch 4 |
| NPL | N-acetylneuraminate pyruvate lyase (dihydrodipicolinate synthase) |
| NPTX1 | neuronal pentraxin I |
| NR1I3 | nuclear receptor subfamily 1, group I, member 3 |
| PLA2G2A | phospholipase A2, group IIA (platelets, synovial fluid) |
| PLVAP | plasmalemma vesicle associated protein |
| PRAMEF12 | PRAME family member 12 |
| PRMT8 | protein arginine methyltransferase 8 |
| PRND | prion protein 2 (dublet) |
| RCAN2 | regulator of calcineurin 2 |
| RDH5 | retinol dehydrogenase 5 (11-cis/9-cis) |
| RDH8 | retinol dehydrogenase 8 (all-trans) |
| REM1 | RAS (RAD and GEM)-like GTP-binding 1 |
| RFPL2 | ret finger protein-like 2 |
| RHOH | ras homolog family member H |
| RNF141 | ring finger protein 141 |
| RNF186 | ring finger protein 186 |
| ROBO1 | roundabout, axon guidance receptor, homolog 1 (Drosophila) |
| SERPINA6 | serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 6 |
| SERPINA7 | serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 7 |
| SERPINF2 | serpin peptidase inhibitor, clade F (alpha-2 antiplasmin, pigment epithelium derived factor), member 2 |
| SLC17A9 | solute carrier family 17 (vesicular nucleotide transporter), member 9 |
| SOX21 | SRY (sex determining region Y)-box 21 |
| SPIB | Spi-B transcription factor (Spi-1/PU.1 related) |
| SPP1 | secreted phosphoprotein 1 |
| SPTBN2 | spectrin, beta, non-erythrocytic 2 |
| ST7L | suppression of tumorigenicity 7 like |
| TAF15 | TAF15 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 68kDa |
| TLN1 | talin 1 |
| TM7SF3 | transmembrane 7 superfamily member 3 |
| TMEM53 | transmembrane protein 53 |
| TMSB4Y | thymosin beta 4, Y-linked |
| TSPAN15 | tetraspanin 15 |
| TSPAN7 | tetraspanin 7 |
| TUBG2 | tubulin, gamma 2 |
| UGT8 | UDP glycosyltransferase 8 |
| USP6 | ubiquitin specific peptidase 6 |
| ZBTB44 | zinc finger and BTB domain containing 44 |
| ZC4H2 | zinc finger, C4H2 domain containing |
| ZNF23 | zinc finger protein 23 |
| ZNF484 | zinc finger protein 484 |
| ZNF623 | zinc finger protein 623 |
